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Mbarara University of Science and Technology (MUST)Mbarara University of Science and Technology (MUST)
Pharm-Biotechnology and Traditional Medicine Centre
An Eastern and Southern Africa Higher Education Centers of Excellence
Project
Mbarara University of Science and Technology
NATIONAL LAUNCH PRESENTATION - 15th NOVEMBER 2017, PRESIDENT’S OFFICE – KAMPALA, UGANDA
Casim Umba Tolo (Ph.D)Director/Centre Leader, PHARMBIOTRAC
Background
● Realising that regional approach to African higher education offers the best leverage to build and sustain excellence required to address key development challenges, ACEII Project come in to fill this gap to realise this potential
● PHARMBIOTRAC focuses on addressing Africa’s low life expectancy and productivity by traditional means…….
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Background…
● Africa’s social, cultural and economic systems are based on her rich biodiversity that remains economically/productively untapped
● Traditional Medicine (TM) and Traditional Medicine Knowledge (TMK) systems form part of this wealth/heritage.
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Background…
● Inadequate number of scientists specialized in TM and pharm-biotechnology is a key challenge in harnessing the benefit of Africa’s biodiversity-to enhance life expectancy & productivity
● In response, MUST through the World Bank’s ACE II Initiative has created, in the region, a unique framework by establishing
“Pharm-Biotechnology and Traditional Medicine Centre” (PHARMBIOTRAC).
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Objectives
Build a critical mass of
specialized and skilled
human resource that can
advance traditional medicine
and Pharm-Biotechnology
for socio-economic
development of Africa,
To Strengthen capacity
in the region to engage
in cutting edge research
in TM and systems
biology for health
products development
To Advance the practices
of TM/TMK in the region
and promote
domestication and
sustainable utilization of
medicinal species
To Create capacity in
collaboration with private sector
industry for development,
production and commercialization
of TM, biopharmaceuticals and
nutraceuticals from research
outputs
To Strengthen capacity in
the region to train highly
skilled and specialized
professionals in traditional
medicine and Bio-
pharmaceuticals,
PHARMBIOTRAC Framework
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Partner engagement
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Envisaged Impact
● Society benefits: Trained TM practitioners
● Industries: Skilled man power in TM and Pharm-Biotechnology, research products for commercialisation
● Academia: Building capacity of staff (MSc and PhD), research capacity (equipment and specialist skills), income from research, training and royalties
● Governments: Facilitate the integration of TM in national health systems
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Mbarara University of Science and Technology (MUST)Mbarara University of Science and Technology (MUST)
Presentation Part II
Patrick Engeu Ogwang, PhDDeputy Centre Leader / Principal Investigator
NATIONAL LAUNCH PRESENTATION
15th NOVEMBER 2017, PRESIDENT’S OFFICE -KAMPALA
Background
● Africa is still the least developed continent in the world
● One of Africa’s development challenges is high burden of diseases and inadequate medicines/solutions .
● Imported solutions to Africa have not helped much, Africa needs her own sustainable solutions.
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http://images.tildacdn.info/e3612829-47c6-408b-8947-46d4f40accd2/GDP_per_capita_clustered_by_continents_Africa_Asia_Europe_North_America_Oceania_South_America_chartbuilder.png
Africa’s Untapped Biodiversity and Knowledge wealth
• Africa has a rich
-Biodiversity of life forms
-Traditional medicine (TM)
-Traditional Medicine Knowledge (TMK) systems
-But these have not been science driven to improve quality of life and productivity in the Africa
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● Examples of medicinal plants in Uganda under testing and development
● ‘Lapena’ ‘Ejobyo’, ‘Omuhoko’‘Emoros’ etc
● Very rich in Active pharmaceutical Ingredients
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Gynadropsis gynadraAfrican Spider Plant - Gasaya
Cajanus cajan - Pigeon pea - Lapena Rumex spp - Dock
Application of Science and Technology—Malaria prevention medicine
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Core Ingredients
Final
Product
Plant based medicine against malaria
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• Reduces malaria and fevers by more than 80% (Ogwang et al 2011, 2012)
• Prof Chang-Hee, (MSU, USA) has run tests in her lab found immune system effects
• 2 PhD candidates working on it is pharmacokinetics and detailed safety in children and pregnant mothers)
• Uganda loses over 600million USD due to malaria. This product can save Uganda 480 million USD every year.
Pharm-biotechnology-Isolation and production of Active Pharmaceutical Ingredients
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Mbarara University of Science and Technology (MUST)
PHARMBIOTRAC Programme at MUST
Core team members
Prof. Celestino
Obua (VC),
Dr. Casim
Umba ToloDr. Ogwang
Patrick Engeu
Eng. Anke
Weisheit
How will the center achieve the aims
● Review of existing curriculum and redesign Masters and PhD programmes to meet Africa’s industry needs
● Introduction of relevant short courses for health-workers and pharmaceutical industry workforce in Africa
● Introduction of short courses for Traditional health practitioners to better their primary healthcare inputs
● Collaborate with national, regional and international academic, research and industry experts as partners to offer best training to students at Masters and PhD level
● Carry out applied research in collaboration with industry and traditional health practitioners
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Current achievements
● Development of three new masters programmes
o Clinical Pharmacy and Alternative medicines
o Pharmaceutical Analysis
o Pharmacognosy and Herbal Drug Production
● Attracted 24 PhDs (8 foreign students from West, Eastern and southern Africa), and 7 masters (3 foreign)
● One resident Professor of Pharmacy from USA
● One applied research funding from Action for Natural Medicines –Germany
● Purchase of modern research equipment and small scale drug manufacturing equipment
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Mbarara University of Science and Technology (MUST)
In the next 5-10 years we want contribute to integration of validated Traditional
Medicine Knowledge and Herbal products into the Healthcare systems in Africa
We thank Governments of Africa in particular Uganda and the world bank for funding our centers of excellence to
develop solutions in Africa for the world
Thank you very much
Mbarara University of Science and Technology (MUST)Mbarara University of Science and Technology (MUST)
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Acknowledgements
Host University: MUST
All PHARMBIOTRAC Partners
(at National, Regional & Internal Level)
Mbarara University of Science and Technology (MUST)
Contact
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Dr. Ogwang Patrick Engeu(B.Pharm, Msc Pharmacol, PhD natural products)
Head of Pharmacy Department, Faculty of Medicine,
Principal Investigator and Deputy Center Leader
Pharm-Bio Technology and Traditional Medicine Centre (PHARMBIOTRAC)
Mbarara University of Science and Technology, Mbarara, Uganda
Mobile line +256-779-617612, +256-703-694244
Emails: [email protected], [email protected]
