PersonnelPlacement

SCIENCE publishes each Friday, except the last Fridayof the year. Advertising is accepted only in writing; noabbreviations. Any deadline in ad must be at least 2weeks after date of issue in which ad appears. Also,personnel advertising is accepted only with the under-standing that the advertiser does not discriminateamong applicants on the basis of race, sex, religion,age, color, national origin, handicap, or sexual prefer-ence. SCIENCE reserves the right, in its discretion, todecline to publish advertisements submitted to it.

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POSITIONS WANTED

Biochemist/Cell Biologist-Ph.D. Experience: tissueculture, protein purification, HPLC/FPLC, PPAGE,PIEF, immunoblot, light and electronmicroscopy, ani-mal models of human cecal/hepatic disease, immuno-staining, isoenzyme analyses, lymphocyte purification,EM facility management, supervision of laboratory per-sonnel, teaching undergraduate/postgraduate biochemis-try/immunology. Seeks teaching/research position. Box98, SCIENCE.

Biochemist/Cell Biologist, Ph.D. Flow cytometry, cellculture, intermediary metabolism, and enzymology expe-rience. Pulmonary biochemistry background. Good pub-lication and funding record. Experience in teachingundergraduate, graduate, and medical students. Seekslong-term position in academia or industry in PacificNorthwest. Box 99, SCIENCE.

POSITIONS WANTED

Cellular Immunologist, Ph.D. Ten years of experiencein immunoregulation, animal models and genetics ofautoimmune disease. Seeks challenging position in aca-demia or industry, New Jersey/Pennsylvania. Experi-enced in research, teaching, grant and publication prepa-ration. Box 100, SCIENCE.

Free-Lance Computer Programmer for research labo-ratories. Reasonable rates. Prefer C on a PC in New YorkMetro area. Background in neuroscience and behavioralpharmacology. Pat O'Connor, 1649 Springfield Avenue,Maplewood, NJ 07040.

Immunologist, Ph.D. Experienced senior-level scientistwith broad-based experience in industry and academiaseeking responsible position in established or start-upbiotechnology company. In-depth experience in tumorimmunology, hybridomas, and large-scale cell culture.Significant project management experience. Box 93,SCIENCE.

M.B.B.S., Ph.D. Experienced in neuropathology ofpoliovirus simian nervous system, potency/field usage ofviral vaccines. Enzymes radio-immunoassays hepatitisviruses/AIDS in hyperendemic regions. Seeks visiting/staff position. Box 102, SCIENCE.

M.D., early retired (age 55) from drug industry seekspart-time or projects; excellent at data interpretation andmedical writing for NDAs, etc. Telephone: 215-794-5581 or Box 86, SCIENCE.

Mass Spectroscopist, Ph.D. Broad and productive re-search experience applying mass spectrometry in thechemical and biolocal sciences. Many publications.Excellent wnting an interpersonal skills. Experienced inall aspects of NIH grant processes. Seeks interdisciplin-ary opportunity at the mid- to senior professional levelin academia, government, or private sector. Box 81,SCIENCE.

Ph.D. Several years of experience in RIA, GC, HPLC,immunoassay development. Over 10 years in reproduc-tive endocrinology research. Last 5 years involved inANF research. Excellent references and publications.Seek academic, industrial, or clinical research position.Box 95, SCIENCE.

Pharmacokinetic, M.A., Ph.D., M.D., 3 years of post-doctoral research, seven publications, experienced indrug delivery/testing in animals, animal surgery, workingknowledge in TLC, HPLC, GC-mass spectrometry pro-tein characterization (including sequencing) desires in-dustrial position; will relocate and travel. Box 103,SCIENCE.

Toxicologist, Ph.D., Board-certified with 10-plus yearsof industrial experience seeks position in Caornia:chemical, consumer product, pharmaceutical, and haz-ardous waste site experience. Box 71, SCIENCE.

POSITIONS OPEN

ACADEMIC HEMATOLOGIST-The Universityof Vermont. Full-time faculty position in the Depart-ment of Medicine in conjunction with the VermontSpecialized Center of Research in Thrombosis. Candi-dates should have documented research performance inhemostasis and thrombosis and/or thrombolysis. Mostlikely, the successful candidate will be a B.E./B.C. physi-cian in an appropriate specialty of medicine or an excep-tionally qualified basic scientist. The application mustprovide evidence of continuing research, support, andmaintenance of an independent research program. Aca-demic rank and salary will be consistent with the appli-cant's qualifications. Please direct inquiries with curricu-lum vitae and names and addresses of three references to:Richard Branda, M.D., Director, Hematology/Oncol-ogy, 32 North Prospect Street, Burlington, VT05401. UVM is an Equal Opportunity/Affirmative ActionEmployer. Women and minorities are encouraged to apply.Applications will be accepted until the position is filled.

POSITIONS OPEN

ANALYTICAL CHEMISTRY MANAGER. Su-pervise chemistry staff and work in full-service laboratorywith GC, GC-MS, A's, and various other equipment.Experience with QA-QC, environmental regulations pre-ferred. Consulting with parent corporation and otherclients in Florida. Full-time, company benefits. Salary to$45,000. Ph.D. or M.S. in chemistry. Resume andreferences to: Environmental Quality Laboratory,Inc., 1009 Tamiami Trail, Port Charlotte, FL 33953.

ASSISTANT DIRECTOR, ACADEMIC AF-FAIRS, College of Agriculture and Life Sciences; 12-month appointment with academic rank of associate orfull professor; minimum of 5 years of teaching, research,and academic advising experience; previous administra-tive experience desirable; preference will be given tocandidates with a background in life sciences. Dutiesinclude working with other members of the administra-tive team, student recruitment, interaction with studentorganizations, and other assignments appropriate to theacademic office of a major colege in a land-grant institu-tion. Nominations and applications should be sent to:Search Committee for Assistant Director-AAS, Box7615, North Carolina State University, Raleigh, NC27695-7615.

Applications should include a complete curriculumvitae and employment history, a statement not to exceedone page describing the applicant's administrative philos-ophy, and the names, addesses, and telephone numbersof three persons who may be contacted by the searchcommittee to evaluate the candidate. Proper documenta-tion of identity and employability will be required beforethe hiring process can be finalized. Closing date forall applications is 15 September 1989. North CarolinaState University is an Afirmative Action/Equal OpportunityEmployer.

ASSISTANT PROFESSORDEPARTMENT OF PHYSIOLOGY

QUEEN'S UNIVERSITYThe Department of Physiology, Queen's University, is

seeking an individual with research accomplishments andinterests in the molecular biology of nerve regenerationto be appointed as an assistant professor. Priority willbe given to an applicant with experience in immunocyto-chemical and in situ hybridization techniques. The suc-cessful applicant will be expected to acquire salary andresearch support through applications to the MedicalResearch Council or other agencies. Candidates of bothsexes are equally encouraged to apply. Applicants shouldsubmit curriculum vitae, a brief statement of their re-search interests and objectives, selected reprints, and thenames of three referees from whom a confidential as-sessment of research and teaching abilities may be ob-tained to: Dr. M. A. Bisby, Department ofPhysiology,Queen's University, Kingston, Ontario, Canada K7L3N6.

Applications will be accepted until 31 August 1989.

ASSISTANT PROFESSORDEPARTMENT OF PHYSIOLOGY

QUEEN'S UNIVERSITYThe Department of Physiology, Queen's University,

wishes to recruit an assistant professor who will conductan independent, externally funded research program andcontribute to the teaching duties of the Department.While preference may be given to applicants working inthe cardiovascular area, those expert in endocrine, gastro-intestinal, respiratory, or renal physiology are also en-couraged to apply. This is a funded special appointmentfor up to a 5-year term, but the successful candidate isexpected to apply to appropriate agencies for scholarshipsupport. Catndidates of both sexes are equally encouraged toapply. In accordance with Canadian Immigration requirements,this advertisement is directed to Canadian citizens andpermanentresidents. Applicants should submit curriculum vitae, abrief statement of their research interests and objectives,selected reprints, and the names of three referees fromwhom a confidential assessment ofresearch and teachingabilities may be obtained to: Dr. M. A. Bisby, Depart-ment of Physiology, Queen's University, Kingston,Ontario, Canada K7L 3N6.

Applications will be accepted until 15 September1989.

PERSONNEL PLACEMENT 877 JULY I989

POSITIONS OPEN

ASSISTANT PROFESSOR-The Department ofAnatomv is seeking applications for a tenure-track assist-ant professor position with teaching in either grossanatomy or histology/neuroscience. A strong researchprogram is essential. Research area is open, althoughpreference wiU be given to candidates in cellular/molecu-lar biology or neurobiology. Ph.D., M.D./Ph.D. orequivalent degrees, at least 2 years of postdoctoral re-search, and a funded or fundable research program arerequired. Submit curriculum vitae and arrange for threeletters of recommendation to be sent by 1 November1989 to: Dr. Joseph T. Weber, Department ofAnato-my, Tulane Medical School, 1430 Tulane Avenue,New Orleans, LA 70112. Tulane is an Equal Opportuni-ty/Affirmative Actiont Employer. Applications from qualifiedvometn atnd ninorities are encouraged.

ASSISTANT PROFESSORDEPARTMENT OF PHYSIOLOGY

QUEEN'S UNIVERSITYThe Department of Physiology, Queen's University,

wishes to recruit an assistant professor in cell physiologywho will conduct an independent, externally fundedresearch program and contribute to the teaching dutiesof the Department. While the excellence of the candidatewill be the most important factor, some preference maybe given to those working in areas that complementexisting strengths in cardiovascular, respiratory, endo-crine, and neurophysiology. Appointment is conditionalupon acquisition of scholarship support from an appro-priate agency. Candidates ofboth sexes are equally encouragedto apply. Itn accordance with Canadian Immigration require-metits, this advertisementt is directed to Canadian citizens andpennatiett residetnts. Applicants should submit curriculumvitae, a brief statement of their research interests andobjectives, selected reprints, and the names of threereferees from whom a confidential assessment of researchand teaching abilities may be obtained to: Dr. M. A.Bisby, Department of Physiology, Queen's Universi-ty, Kingston, Ontario, Canada K7L 3N6.

Applications will be accepted until 15 September1989.

ASSISTANT PROFESSOR, MICROBIOLOGY.The Department of Microbiology and Immunology,University of North Dakota School of Medicine, invitesapplications for a tenure-track position at the level ofassistant professor. Candidates should have a Ph.D. andpostdoctoral experience. The appointee is expected todevelop a competitive research program, participate inthe teaching of medical and general microbiology, anddevelop a course in his/her specialty. Although researchinvolving a molecular approach to microbial pathogene-sis, microbial biochemistry/physiology, or environmentalmicrobiology is preferred, other research areas will beconsidered. Review of applications will begin 15 Sep-tember 1989. Applicants are to provide a letter ofapplication, curriculum vitae, a statement of researchwith representative publications, and the names andtelephone numbers of three references to: Dr. James J.Kelleher, Chairman, Department of Microbiologyand Immunology, Schoofof Medicine, University ofNorth Dakota, Grand Forks, ND 58202.UND is an Equal Opportunity/Affirmative Action Employer.

ASSISTANT/ASSOCIATE PROFESSOROF ANATOMY AND CELL BIOLOGY

The Department of Anatomv and Cell Biologv atWayne State Universitv invites applications for a tenure-track position at the assistant/associate professor level.The department is seeking an individual whose researchwill complement the interests of the present faculty. Thetwo major areas of research are developmental neurosci-ences and vision research. Applications are invited fromcandidates utilizing genetic, molecular, or cellular meth-odologies. The successful candidate will be expected toparticipate actively in the teaching program and toestablish a funded, independent research program. Excel-lent start-up funds and laboratory space are available.Intra- and interdepartmental collaboration is fostered bya core vision grant to the department and a neurosciencesprogram. Applicants should have a Ph.D. or an M.D.degree and several vears of postdoctoral training. Pleasesubmit a covering letter with curriculum vitae and thenames of three references to: Dr. Harry Maisel, Chair-man, Department of Anatomy and Cell Biology,Wayne State University School ofMedicine, 540 EastCanfield, Detroit, MI 48201.

Affirmative Action/Equal Opportutnity Employer.

POSITIONS OPEN

ASSISTANT PROFESSORPHYSIOLOGY AND BIOPHYSICS

Applications are being accepted for a tenure-trackposition at the assistant professor level. Responsibilitieswill include participation in team teaching medical andundergraduate physiology, graduate education, and es-tablishment of an extramurally funded research program.Applicants should have the M.D. or Ph.D. degree andpostdoctoral experience. We encourage candidates whoseresearch interest is in the neurosciences, but will considercreative work in other contemporary areas of physiologi-cal research. Review of applications will begin 1 October1989 and continue until the position is filled. Curricu-lum vitae, a brief description of current and futureresearch interests, and names of three or more referencesshould be sent to: Dr. Rex Stith, Department ofPhysiology and Biophysics, University of OklahomaHealth Sciences Center, P.O. Box 26901, OklahomaCity, OK 73190.An Equal Opportunity/Affirmative Action Employer. Wom-

en atid mitnorities are encouraged to apply.

ASSISTANT PROFESSORVISUAL CORTICAL NEUROPHYSIOLOGYApplications are invited for a tenure-track position in

the Department of Neuroscience at the University ofFlorida College of Medicine in Gainesville. Applicantsshould have an M.D. or Ph.D. and postdoctoral experi-ence. Evidence of an active, independent research pro-gram in the awake behaving primate would be particular-ly welcome. Anticipated start date will be 1 January1990. Please send curriculum vitae, statement of researchinterests, and three letters of reference before 31 July1989 to: Christiana M. Leonard, Chair, Visual Neu-roscience Search Committee, Department of Neuro-science, Box J-244, J. Hillis Miller Health Center,Gainesville, FL 32610-0244. An Equal Opportunity/Afirmative Action Employer.

HARVARD UNIVERSITYDepartment of Earth and Planetary Sciences invites

applications for TWO ASSISTANT PROFESSORPOSITIONS in seismology. We hope to build on ourstrength in the studies of earth structure, earthquakeprocesses, and geodvnamics. We expect that full benefitfrom the data recorded by the global, regional, andtemporarily deployed digital seismograph networks willinvolve advanced methods of waveform analysis. There-fore, we are primarily interested in candidates withsubstantial theoretical abilities and experience in model-ing wave propagation in laterally heterogeneous media.

Applicants should send a statement of research inter-ests, resume, and names of at least three references to:Professor Adam M. Dziewonski, Chairman, SearchCommittee, Department of Earth and Planetary Sci-ences, Harvard University, 20 Oxford Street, Cam-bridge, MA 02138.

ASSISTANT RESEARCH MICROBIOLOGISTA process-oriented microbial ecologist is sought for a

non-tenure-track, grant-funded research position to in-vestigate microbial transformations of detrital lignocellu-loses in aquatic ecosystems. Ph.D. in ecology and post-doctoral experience required. Candidate will have experi-ence in the preparation and use of radiolabeled lignocel-luloses in geochemical and trophodynamic studies and insimulation modeling of detritus dynamics. Send curricu-lum vitae and three letters of recommendation by 31August 1989 to: R. E. Hodson, Department ofMscro-biology, University of Georgia, Athens, GA 30602.The Untiversity of Georgia is an Equal Opportunity/Affinna-tive Action Institution.

CARDIAC MEMBRANE STRUCTURE ANDFUNCTION. NIH-finded postdoctoral training posi-tions available 1 Julv 1989 for up to 3 years in researchtraining in cardiac physiology, pharmacology, biochem-istry, and biophysics at NIH stipend levels. Minimumrequirements: Ph.D. or M.D. degree. Qualified mitnoritycandidates are encouraged to apply. For fither information,contact: Arnold M. Katz, M.D., Cardiology Division,University of Connecticut Health Center, Farming-ton, CT 06032.An Afirmative Action/Equal Opportunity Employer

M/W/H.

POSITIONS OPEN

ASSISTANT PROFESSORMOLECULAR BIOLOGY

Well-trained molecular biologist to join active researchlaboratory investigating the regulation by certain cyto-kines and growth factors ofgene expression in cells of theimmune system. Knowledge of gene cloning, sequenc-ing, vector construction, site-directed mutagenesis, SInucleus mapping, nuclear binding (footprinting, etc.)and other molecular techniques necessary. Tenure-trackposition available to the successful candidate. Send cur-riculum vitae, research experience, and names of threereferences to:

M ()RIAI INSI'li If

Institute DirectorRoswell Park Memorial Institute

Elm and Carlton StreetsBuffalo, NY 14263

RPMI is atn Affirmative Action Employer.

DIVISION OF NUTRITIONAND ENDOCRINOLOGY

ASSISTANT OR ASSOCIATE RESEARCHSCIENTIST (B.S./M.S.) to carry out studies concernedwith the role of hormones in breast cancer and thebiological action of a new antiestrogen for breast cancertreatment. The position requires a knowledge of serumhormone and receptor assays, and specificalvy, expertisein radioimmunoassay.

This appointment is wvell-suited to an individual seek-ing either a career in clinical laboratory endocrinology orbasic endocrine research at a modern, well-equippedresearch facility located in a northern suburb of NewYork City. Please submit curriculum vitae to:

Dr. David P. Rose, Division ChiefAmerican Health Foundation

Division of Nutrition and Endocrinology1 Dana Road

Valhalla, NY 10595An Equal Opportunity Emnployer M/F/H/V.

BIOCHEMISTRY/MOLECULAR BIOLOGYMEHARRY MEDICAL COLLEGE

FACULTY POSITIONS are expected to be availablein 1990 in the Department of Biochemistrv at the level ofassistant or associate professor for well-trained or experi-enced candidates in the following areas: (i) molecularbiology of eukaryotic systems, (ii) membrane biochemis-try or molecular biology of signal transduction, and (iii)regulatory aspects of cellular and/or metabolic biochem-ist. Successful applicants will be expected to developandor maintain a funded research program of higquality, to participate in the graduate and professional(medical, dental, and allied health) school teaching pro-grams of the Department, and to interact with institu-tional programs in neuroscience and ceWllmolecular biolo-gy.Applicants should send curriculum vitae, names ofour in ividuals who may be contacted for reference, anda summary of potential research projects to: Ifeanyi J.Arinze, Ph.D., Chairman, Department of Biochemis-try, Meharry Medical College, Nashville, TN 37208.Meharry Medical College is ani Equal Opportunity/AffirnativeAction Employer.

DIRECTOR, MICROSCOPY FACILITY, assist-ant or associate research biologist level (DOE). Dutiesinclude supervising staff, training students, and assistingin research. Requires familiarity with latest techniques oflight and electron microscopy. Appointrnent will be for 1year with the possibility of reappointment on an annualbasis in accordance with applicable personnel policiesand availability of funding. Funding for one-half positionis to be generated by the applicant. Requires Ph.D. inbiological field and 1 to 2 years of experience. Submitcurriculum vitae and names of three references to: Dr.Leslie Wilson, Chairman, Department of BiologicalSciences, University of California, Santa Barbara, CA93106, by 1 September 1989. Proof of U.S. citizenshipor eligibility for U.S. employment will be required priorto employmenit. An Equal Opportunity/Affirmative ActionEmployer.

SCIENCE, VOL. 24588

POSITIONS OPEN

DEPUTY DIRECTOR GENERALDIRECTOR OF RESEARCH

A Central American-based Agricultural Research Cen-ter actively involved in experimental station and on farmresearch for various tropical fruits and vegetables such asbananas and plantains, winter squash, raspberries, on-ions, lima beans, asparagus, mangos, cacao, etc. is look-ing for:A DEPUTY DIRECTOR GENERAL to plan, di-

rect, supervise, and evaluate the administrative/technicaloperations of the institution, supervise/oversee the ap-propriate use of fiscal, financial, and human resources;assist in the preparation of the Annual Plan ofWork andBudget.A DIRECTOR OF RESEARCH to plan, develop,

and supervise programs and projects for research; super-vise the oprational units to ensure proper developmentof plan o work, research activities, communications, andtececal services.

Candidates must have a Ph.D. or master's in one oftheagricultural sciences; minimum of 5 years of experiencein agricultural research and research administration; befluent in both English and Spanish.

Interested candidates shoud send resume, references,and salary history to: C. H. Smith, Arthur Young,3000 K Street, NW, Washington, DC 20007 (no callsplease).

DIRECTOR OF ANATOMIC PATHOLOGY-University of California School of Medicine at SanFrancisco is seeking a full-time academic pathologist atthe associate or full professor tenure-level or the UCSFMoffitt-Long Hospital. Candidate expected to share inservice and teaching; subspeciality pathology interestdesirable. The option exists to be Director of SurgicalPathology. Anatomic Pathology Board certification andCalifornia license are required. Send curriculum vitae to:Surgical Pathology Search Committee, Departmentof Pathology, Umversity ofCalifornia, San Francisco,CA 94143-0506. UCSF is an Equal Opportunity/Af-firmative Action Employer. Women and minorities encouragedto apply.

ECOTOXICOLOGISTExxon Biomedical Sciences, Inc. has an immnediate

opening for a qualified individual specializing in ecotoxi-cology and environmental hazard assessment. The suc-cessful candidate will have a Ph.D. in ecotoxicology or inan environmentally related field with 0 to 2 years ofpostdoctoral expenence. Experience in or a knowledge ofthe application of both effects and fate data to real worldconcerns as well as knowledge ofregulatory requirements(TSCA/PMN) would be desired.Exxon Biomedical Sciences, Inc. performs both con-

sulting and laboratory toxicology for affiliates around theworld. Its resources include state-of-the-art aquatic toxi-cology, environmental chemistry, and mammalian toxi-cology laboratories. The candidate will perform as astudy monitor and internal consulting toxicologist. Cli-ent interactions are an important aspect ofour work, andthus, we are also seeking an individual who has excellentcommunication skills. Please forward resumr to: HumanResources:

Exxon Biomedical Sciences, Inc.CN 2350, Mettlers Road

East Millstone, NJ 08875-2350Equal Opportunity Employer M/F/H/V

EUKARYOTIC MOLECULAR BIOLOGISTAssistant professor, tenure-track position at Kenyon

College. Candidates should have a Ph.D., active researchprogram that will involve undergraduates, and evidenceof excellence in teaching. Consideration will be given toall types of eukaryotic research utilizing tools of molecu-lar genetics and/or molecular immunology irrespective ofthe eukaryotic organism of study. Teaching duties in-clude molecular biology and introductory courses. Thecollege provides support for start-up costs. Interestedindividuals should submit curriculum vitae, graduate andundergraduate transcripts, three letters of reference, anda description of teaching and research interests by 1November 1989 to: Dr. Dorothy Jegla, Biology De-partment, Kenyon College, Gambier, OH 43022.

An Equal Opportunity Employer.

The Institute for Arthritis and Autoimmunity (IAA) is engaged in amajor expansion of its staff. IAA is the newest of four major researchgroups located at the newly-formed Miles Research Center in WestHaven, CT near the Yale University Campus. The Center functions as amajor research resource of Bayer AG of West Germany and its subsi-diary, Miles Inc.IAA is seeking applicants with a BS or MS to participate in researchprograms devoted to the study and treatment of inflammatory dis-eases. Specific areas of our research interest are described below:

U Leukocyte Biology GroupWe are seeking an individual who will conduct studies concerned withthe physiology, biochemistry and molecular biology ofmammalian andhuman leukocytes. This individual should possess an MS with 3 yearsor a BS degree with 5 or more years of laboratory experience in eitherimmunology, biochemistry, or cell biology. Experience in cell culture,protein purification and characterization by various electrophoretictechniques, as well as enzymology is imperative. Additional experiencein the isolation of cells from blood and exudate, immunological, molecu-lar biological, and biochemical characterization of effector cells wouldbe useful.

* Cartilage Metabolism GroupPosition available immediately to study the involvement of metallo-proteases in cartilage metabolism with special regard to osteoarthri-tis. Applicants should possess a BS and/or MS degree and 2-3 years oflaboratory experience in recombinant DNA and/or protein biochemis-try. A strong background in screening cDNA libraries, DNA sequencing,northern, southern and western blotting, transfection, and/or proteinpurification, enzyme assays, and tissue culture is desirable.

U Histology GroupIAA is seeking a BS or MS with 5 or more years of experience inhistology. This individual will be responsible for establishing and oper-ating a histology laboratory. Experience with either frozen or hardtissue sectioning is required.The positions offer attractive compensation commensurate with qual-ifications, generous benefits, and an excellent opportunity for personalgrowth and professional satisfaction. Resumes should be forwardedto: Department ACE, Miles Research Center, 400 Morgan Lane, WestHaven, CT 06516.

An Equal Opportunity Employer M/F/H/V

7 JULY I989

I

lots

I

PRODUCTDEVELOPMENTSPECIALIST

Amgen, an innovative leader in the development ofhuman pharmaceuticals through applied recombinantDNA technology, has an immediate opportunity in ourTherapeutic Group for a Product Development Spe-cialist. Responsibilities will include assisting in logisticsplanning and management of various aspects ofG-CSF development, including clinical studies,research, preclinical investigation, manufacturing,supply and registration.

Candidates for this position must have 3 to 4 years'experience in the pharmaceutical or health care indus-try, preferably in clinical studies monitoring or studycoordination. Previous experience in the managementof clinical studies is desirable but not essential.

Amgen offers a stimulating and challenging environ-ment on the leading edge of pharmaceutical develop-ment as well as an excellent compensation package. Ifyou have the necessary qualifications and would like tobe a part of a rapidly growing company, please send aresume, in confidence, to:

AMGEN, INC.Recruitment, Dept. #3971900 Oak Terrace LaneThousand OaksCA 91320EqualOpportunityEmployer AMOEN

Postdoctoral TrainingToxicology and Carcinogenesis

Positions available for study in various aspects of cancerresearch and toxicology through the Departments ofBiochemistry, Chemistry, Medicine, Pharmacology, andPathology. Areas of investigation include syntheticchemistry related to toxic chemicals, mechanistic bio-organic chemistry, chemistry of heavy metal antidotes,DNA-carcinogen physical interactions, enzymology ofanimal and human cytochromes P-450 and chromatinproteins, the basis of metal carcinogenesis, chromatinfunction, hepatocarcinogenesis, eicosanoids, regulationof glutathione metabolism, and NMR and mass spectro-metry. Salaries are negotiable.

Ian A. BlairRobert C. BriggsRaymond F. BurkPeter GettinsF. Peter Guengerich

Thomas M. HarrisMark M. JonesR. Stephen LloydLawrence J. Mamett

Applicants should submit curriculum vitae and threeletters of recommendation to Dr. F. P. Guengerich,Director, Center in Molecular Toxicology, VanderbiltUniversity, School of Medicine, Nashville, TN 37232.

An Affirmative Action/Equal Opportunity Employer

CURRENT DISTRIBUTION 160,000

Project LeaderNatural Products ChemistryPfizer is recognized as a worldwide leader in the discov-ery and development of novel pharmaceuticals. Wecurrently have an exceptional opportunity available for anexperienced PhD Chemist to join the Natural ProductsDiscovery and Screening Department as a project leaderin natural products chemistry. Located at our expandingCentral Research facilities in Groton, Connecticut, you willbe responsible for coordinating the activities of a group ofscientists engaged in the isolation and structure determi-nation of natural products expressing biological activity ina variety of therapeutic areas. The position requires strongcommunication and interpersonal skills in addition to tech-nical competence in contemporary structure elucidationmethods and separation techniques.Pfizer offers an excellent salary and comprehensive bene-fits package as well as the opportunity to pursue a stimu-lating career in an atmosphere created for the encourage-ment of interdisciplinary cooperation and professionalachievement.

For consideration, please submit your resume to:Charles P. Norris, Supervisor Employee Resources, PfizerInc., Central Research Laboratories, Eastern Point Road,Groton, Connecticut 06340. An equal opportunityemployer.

THE

SCIENCERECRUITMENT

"FOUR DAY CLOSE"NOW YOU CAN SEE YOUR AD IN SCiENCE

FOUR DAYS AFTER SUBMISSIONScientific Recruiters can now advertise positions almost assoon as the need arises. Instead of reserving space a month ormore in advance, you can now place your ad four days beforethe magazine mailing date. SCiENCE is mailed on the cover date.Film (right-reading, emulsion face down) or full camera readyart and insertion order must reach: SCIENCE, Short Close Desk,1515 Broadway, New York, NY 10036 by NOON Mondays(except for legal holidays when material must reach New Yorkby Noon Fridays). Because space is limited, the four-day closepage will be reserved on a first-come, first-served basis, at a15% premium. 1/4 and 1/2 page ads only.Now you don't have to wait to find the researchers you needimmediately, nor must you advertise in a Sunday paper thatpans a lot of sand, but not much gold. Scientific employersknow that SCiENCFE ads fill the job better. Now they fill it fastertoo.You can call it "INSTANT RECRUITMENT."For further information, telephone Ed. Keller, Recruitment Ad-vertising Manager, or Donna Rivera, Production Manager atSCiENCE: 212-730-1050, or write to: SCiENCE, 1515 Broadway,NY, NY 10036.

I

V~ V~I f 11k- f0 fS: A2 A'mt:: ~w w w w w w

ANNOUNCINGNATIONAL RESEARCH COUNCIL

POSTDOCTORAL RESEARCH ASSOCIATESHIP AWARDS IN

BIOTECHNOLOGYAT THE NATIONAL INSTITUTES OF HEALTH

Research opportunities include:* MOLECULAR BIOLOGY * CELL & STRUCTURAL BIOLOGY * CHEMICAL PHYSICS* MOLECULAR GENETICS * PHYSIOLOGY * COMPUTER SCIENCE* BIOCHEMISTRY * IMMUNOLOGY * MATHEMATICS

The National Research Council in cooperation with the National Institutes of Health conducts three annual com-petitions for research awards for independent scientific research. Recipients will be free to pursue research prob-lems of their own choice as guest investigators at NIH. Duration of award is one year renewable to a maximumof three. Annual stipends start at $28,000. Relocation reimbursement and funds for professional travel on tenureare available, and a health insurance program is provided.

Deadlines for application: August 15, 1989, January 15, April 15 and August 15, 1990 for competitions to beheld in October 1989 and February, June and October 1990 respectively.

For application materials and further information concerning specific participating Institutes and Laboratories, write to:Associateship Programs

(GR 430A/H)NATIONAL RESEARCH COUNCIL

2101 Constitution Avenue, NW * Washington, DC 20418 * FAX: (202) 334-2759

BUILDING ANEW LAB?

LET THE SCIENCE FREE PRODUCTINFORMATION SERVICE PUT YOU INTOUCH WITH THE VENDORS WHOSEPRODUCTS YOU WILL NEED.

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Applications are invited for a chair in

CHEMICAL CRYSTALLOGRAPHYat the Organic Chemistry Laboratory of the ETHZurich.

The post requires participation in teaching chemis-try at the undergraduate level. In research the newprofessor is expected to apply crystallographicmethods to the solution of problems of structureand reactivity involving low and high molecularweight compounds, including those of biologicalrelevance, and to interact with other researchgroups.

Candidates will have an advanced university de-gree, internationally recognized contributions toone of the above mentioned fields and a provenability to conduct high quality research. Enthusi-asm to teach at all university levels and willingnessto cooperate with colleagues within and outsidethe university are indispensable.Applications with curriculum vitae and list of publi-cations (no publications) should be submitted be-fore September 15, 1989, to the President of ETHZurich, Prof. Dr. H. BuhImann, ETH-Zentrum, CH-8092 Zurich.

m J.U -I I

POSITIONS OPEN

FACULTY IN BIOTECHNOLOGYApplications are invited for tenure-track faculty in the

Department of Biology, Indiana University-PurdueUniversity at Indianapolis. Applicants for the positionsshould have a Ph.D. degree, postdoctoral training, andexperience in state-of-the-art mammalian molecular ge-netics or protein biochemistry; a history ofgrant supportis highly desirable. Successfu candidates will be expectedto establish cooperative educational initiatives with Indi-anapolis industry; develop an active, externally fundedresearch program; and contribute to the continued devel-opment of the M.S. and Ph.D. programs in biotechnolo-gy. The position will require a substantial teachingcommitment. Individuals with a record of outstandingscientific achievement may be appointed to the rank ofassociate professor. The review ot applications will begin1 September 1989 and continue until the positions arefilled. Applicants should send their curriculum vitae, astatement of their research interests, reprints of recentpublications, and four letters ofrecommendation to: Dr.Charles Schauf, Professor and Chairman, Depart-ment of Biology, Purdue University School of Sci-ence, 1125 East 38th Street, Indianapolis, IN 46205.Indiana University is an Equal Opportunity/Affirmative AaionEmployer. Women and minority candidates are particularlyencouraged to apply.

FACULTY POSMONDirector, Core Facility in Protein Chemistry. The

University ofTexas Heal= Science Center, San Antonio,invites applications for a faculty-level position to direct aCore Facility for protein isolation. anddates will beexpected to have training and expertise in protein chem-istry and the operation of state-of-the-art equipment forprotein ricrosequencing, peptide synthesis, and aminoacid analysis. Equipment avaiable in this core include anABI 477A pulsed liquid phase protein microsequencer,an ABI 431 peptide synthesizer, a Micro-VAX 2000-based Waters 860 chromatography data analysis system,Waters pico-tag amino acid analysis system, and numer-ous other HPLC systems. The successfil candidate willhave opportunities to develop an independent programof research. Submit curriculum vitae and brief descrip-tion of research interests to: Dr. Gregory R. Mundy,Professor and Head, Division of Endocrinology andMetabolism, University ofTexas Health Science Cen-ter, 7703 Floyd Curl Drive, San Antonio, TX 78284-7877. The University of Texas Health Science Center is anEqual Opportunity/Affirmative Action Employer.

UNIVERSITY OF TEXASSOUTHWESTERN MEDICAL CENTER

FACULTY POSMIION in biochemistry and molecu-lar biology. The Department ofBiochemistry is seeking atalented individual for a tenured position as professoravailable in fall 1989. Applicants must have a provenrecord of accomplishment in research in the genetics andmolecular biology of organelle biogenesis. Applicantsshould be interested in teaching medical and graduatestudents in selected areas of biochemistry, genetics, andmolecular biology. In addition, applicants should bewilling to assume responsibilities in graduate recruitmentand administration. Applicants should submit curricu-lum vitae, brief summary of research accomplishments,and three letters of reference by 15 August 1989 to:Faculty Search Committee, Department of Biochem-istry, University ofTexas Southwestern Medical Cen-ter, Dallas, TX 75235-9038. An Equal OpportunityEmployer.

HEAD, DEPARTMENT OF BIOCHEMISTRY.Oklahoma State University invites applications and nom-inations for the position of Head, Department of Bio-chemistry. Candidates should have a distinguished re-cord in research and teaching. Applicants should sendcurriculum vitae including information about adminis-trative experience, names and addresses offive references,and a letter describing the candidate's strengths for theposition. Minorities and women are encouraged to apply.Nominations, applications, and requests for additionalinformation should be sent to: Margaret Essenberg,Chair, Search and Screen Committee, OklahomaStatc University, Stillwater, OK 74078-0454. Tele-phone: 405-744-6189. Review of applications willbegin 15 September 1989.

92

FACULTY POSITION INATMOSPHERIC CHEMISTRY

Applications are invited for an open-level, tenure-trackatmospheric chemistry position. Position is joint be-tween Department of Soil and Environmental Sciences(67% teaching) and Statewide Air Pollution ResearchCenter (33% research). Appointee is expected to developan independent research program related to the forma-tion and fates of airborne constituents and to teachundergraduate and graduate courses in the science ofpolluted air. Candidates for appointment with tenuremust have clearly demonstrated strengths in research andteaching. Potential candidates are requested to submitcurriculum vitae, a statement of teaching/research inter-ests, any supporting documentation, and names, address-es, and telephone numbers of at least three references to:L. J. Lund, Chairman, Department of Soil and Envi-ronmental Sciences, University of California, River-side, CA 92521. Applications will be accepted until 1September 1989. UC is an Equal Opportunity/AffirmativeAction Employer.

FACULTY POSITION IN CELL BIOLOGY.Tenure-track assistant/associate professor position avail-able June 1990 for applicants with a cef or molecularapproach to mammalian biology. Research interests inthe department include cell-cell communication, molecu-lar endocrinology, developmental reproductive biology,or cellular neurobiology. Teaching responsibility in cellbiology/histology. Send curriculum vitae and three let-ters of reference to: Reid L. Norman, Cell Biology andAnatomy, Texas Tech University Health SciencesCenter, Lubbock, TX 79430. TTUHSC is an EqualOpportunity/Afirmative Action Employer.

INFECTIOUS DISEASES/MOLECULAR BIOLOGIST

TENURE-TRACK FACULTY POSITIONThe Department ofPathobiological Sciences is seeking

an individual with trainigin imolecular asnects of infec-tious disease research, preferably bacterial diseases. Salaryand rank commensurate with trainng and experience.Send curriculum vitae and names of at least three refer-ences to: Dr. R. D. Schultz, Professor and Chairman,Department of Pathobiological Sciences, School ofVeterinary Medicine, University ofWisconsin-Madi-son, 2015 Linden Drive West, Madison, WI 53706.Telephone: 608-263-9888. Equal Opportunity/Affirma-tive Action Employer.

MARINE MINERALS COORDINATORFull-time permanent position. Starting salary approxi-

mately $2200 to $2500 per month plus generous frnge:available 1 October 1989. Location is Portland, Oregon.Graduate degree and marine minerals experience re-quired. Minimum of4 years of progressively responsibleexperience in acquisition, evaluation, interpretation, andmanagement of marine technical and/or economic data.The successful candidate will provide marine mineral

resource input to a multidisciplinary offshore state plan-ning effort for the Oregon coast and offshore area.

Duties include management of the departmentes ma-rine minerals program, negotiating an administeringcontracts for offshore studies, planning and conductingmeetings and symposia, writing and presenting clear andconcise reports and publications, participating in thegeologic aspects of coastal land-use planning, and off-shore resource planning. Also includes effective commu-nication with a diverse public, providing the publicservice role for the Department on offshore issues andserving on offshore planning committees. Close coordina-tion is required with the public, local government andfederal, state, university, and industry counterparts.

If interested, send resume and three references (namesand telephone numbers) from present and previoussupervisors. Also request an application packet from:

Oregon Department of Geology andMineral Industries

1400 S.W. Fifth Avenue, Room 910Portland, OR 97201

Telephone: 503-229-5580Deadline for receipt of completed application packet is

1 September 1989. An Equal Opportunity Employer.

HEALTH SCIENTISTThe Environmental Criteria Assessment Office

(ECAO) ofthe Environmental Protection Agency (EPA)is seeking candidates for a health scientist position, GS12-13 ($34,580 to $53,460 per year, based on qualifica-tions), located at Research Triangle Park, North Caroli-na. The principal duties include development of healthhazard assessments of air pollutants and research todevelop improved methods to perform such assessments.Only U.S. citizens are eligible. The essential qualificationsinclude an advanced degree in toxicology or a closelyrelated biological discipline such a pharmacology, physi-ology, biochemistry or immunology (equivalent experi-ence may be substituted); a minimum of 1 year ofprofessional experience as a principal investigator intoxicology or health risk assessment research; publica-tions and presentations at national scientific meetings ontoxicology or health risk assessment; and ability toperform health hazard assessments. Expertise in nala-tion toxicology is desirable, but not required. Pleasesubmit SF-171 and supporting documentation by 31July 1989 to: Dr. Lester Grant c/o Martha Strobel,EPA MD-29, Research Triangle Park, NC 27711.Further information call: Martha Strobel 919-541-4518. EPA is an Equal Opportunity/Afirmative ActionEmployer.

MATHEMATICAL GENETICIST. A tenure-trackassistant professor-level position is available for a Ph.D.mathematical geneticist to join the faculty of the Depart-ment of Psychiatry, University of Utah Medical Center.The Department of Psychiatry has ongoing moleculargenetic linkage studies of schizophrenia, manic-depres-sion, and Tourettes, in collaboration with the HowardHughes Medical Institute at Salt Lake City. Applicantsshould have research expertise in genetic linkage analysisand statistics. Salt Lake City is an urbane and culturedenvironment (Utah Symphony, Ballet West) surroundedby high mountains and life-threatening ski slopes. Con-tact: William F. Byerley, Associate Professor, Depart-ment of Psychiatry, 50 North Medical Drive, SaltLake City, UT 84132. The University of Utah is an EqualOpportunity/Afirmative Action Employer. Deadline: 30September 1989. Applications will be accepted after thedeadline if qualified person has not been identified.

MEDICINAL CHEMISTRYFACULTY POSITION

BIOLOGICAL NMR SPECTROSCOPYThe Department of Medicinal Chemistry, The Ohio

State University, invites applications for a tenure-trackassistant professor position beginning as soon as possi-ble. Candidates should have a Ph.D in medicinal chemis-try, chemistry, or biochemistry, and the desire to developa strong graduate research program in the application ofNMR spectroscopy to molecular biology and drug de-sign. Teaching will be at both the undergraduate andgraduate levels. Applicants should send curriculum vitae,a proposed research program, and arrange to have threeletters ofrecommendation sent to: Professor Donald T.Witiak, Chairnan of the Faculty Search Committee,Department of Medicinal Chemistry, College ofPharmacy, The Ohio State University, Columbus,OH 43210. The review of the candidates will begin 1September 1989. The Ohio State University is an EqualOpportunity Educator and Employer and specifically invites andencourages application from women and minorities.

PENN STATE. MOLECULAR ANTHROPO-LOGICAL GENETICIST. The Department of An-thropology seeks a human molecular geneticist for itsAnthropological Genetics Laboratory. This tenure-trackposition, at the assistant to junior associate professorFevel, to apply genetic methods to the basis, origins, andevolution of human biological variation. Exceptionalliving conditions are accompanied by excellent resources.Department has tradition of leadership in biologicalantopology. Send curriculum vitae and names of threereferences to: Kenneth M. Weiss, Head, Departmentof Anthropolopy, Penn State University, Box S, 409Carpenter Building, University Park, PA 16802.Telephone: 814-865-2509. Apply by 15 September1989; search will remain open until candidate has beenfound. An Equal Opportunity/Affirmative Action Employer.Women and minorities are encouraged to apply.

SCIENCE, VOL. 245

POSITIONS OPEN POSITIONS OPEN

Due to continued growth in our thrombosis programs, we areseeking a Principal Investigator with a Ph.D in Pharmacology,Physiology, Biochemistry or related area. Experience in any of thefollowing areas would be desirable: platelet physiology, animalmodels of thrombosis, biochemistry of thrombosis. The ResearchScientist will play a key role as a member of a multidisciplinarygroup with expertise in pharmacological, biochemical andmolecular biological aspects of thrombosis and thrombolysis.

At Du Pont you'll find a stimulating scientific environmentin a modern research facility located near Wilmington, DE. OurMid-Atlantic location offers a wide range of academic, cultural andrecreational activities. We provide excellent compensation, benefitsand relocation assistance. Qualified candidates should send a cur-riculum vitae with three references to: Professional Staffing Sec-tion, Employee Relations Dept., Room X-51730, Du PontCompany, Wilmington, DE 19898.

An Equal Opportunity Employer M/F/H/V|ff ~ iJ |J U.S. Citizenship or Permanent Visa Required

and meet other appropriate IRCA requirements.c. US PvA*raol

National Cancer InstituteNational Institutes of Health,

Public Health Service

CANCER PREVENTIONFELLOWSHIP PROGRAM

The Division of Cancer Prevention andControl (DCPC) is accepting applicationsfor the Cancer Prevention FellowshipProgram (CPFP). The purpose of thisprogram is to attract individuals from amultiplicity of health science disciplinesinto the field of cancer prevention andcontrol. The program provides for:Participation in the DCPC CancerPrevention and Control Academic Course;Working at NCI directly with individualpreceptors on cancer prevention andcontrol projects; Brief assignments incancer prevention and control programsat cancer centers, State HealthDepartments or other institutions. Fundingpermitting, ten Fellows will be acceptedfor up to three years of training, beginningJuly 1, 1990. Benefits include selectedrelocation and travel expenses, paidfederal holidays, and participatory healthinsurance.

ELIGIBILITY1. M.D. or D.O. from a U.S., territorial,

or Canadian Medical School.Foreign medical graduates musthave current ECFMG/FMGEMScertification and one year residencyin a training program approved bythe Accreditation Council forGraduate Medical Education.

OR2. Ph.D., Dr. RH. or other doctoral

degree in a related discipline(epidemiology, biostatistics, bio-medical, nutritional, public health orbehavioral sciences). Foreigneducation must be comparable tothat received in accredited U.S.,territorial, or Canadian institutions.

3. U.S. citizenship or resident alieneligible for citizenship within fouryears.

For details and application packet send aPOSTCARD with your name and homeaddress to:

Douglas L. Weed, M.D., Ph.D.Cancer Prevention FellowshipProgramDivision of Cancer Prevention andControlNational Cancer InstituteExecutive Plaza South, T-41Bethesda, MD 20892

Further inquiries: Mrs. Barbara Redding,(301) 496-8640 or 496-8641.

DEADLINE FOR RECEIPT OFAPPLICATIONS: SEPTEMBER 8,1989.

Q ZIN,~>

NIH IS AN EQUAL OPPORTUNITYEMPLOYER

f,*- Natural Sciences and Engineering Conseil de recherches en sciencesResearch Council of Canada naturelles et en genie du Canada

NSERC INTERNATIONAL FELLOWSHIPS1989-90

The Natural Sciences and Engineering Research Council of Canada (NSERC) has recently initiated aprogram of International Fellowships to provide foreign doctoral graduates with the opportunity tofurther their research training and experience. These awards are tenable in Canadian universities.

Eligibility: Applicants must have earned a doctoral degree in science or engineering from arecognized foreign university within the last five years. Equivalent research experience may also beacceptable. Candidates must not be Canadian citizens nor permanent residents of Canada.

Duration of Tenure: Appointments are made for one year; renewals for a second year are possible.

Stipend: Fellowships have an annual value of $28,000 plus a travel allowance.

Application Procedures: Applications must be submitted directly to the university department inwhich it is proposed to hold an award. Candidates must not apply to more than one university.

Date of Submission: The deadline for receipt of applications by the proposed host university isDecember 1, 1989.

For further information, contact the:

International Fellowships OfficeNatural Sciences and Engineering Research Council200 Kent StreetOttawa, OntarioCANADAKiA 1H5Telephone: (613) 992-9169

Canada

kg

9 I

POSITIONS OPEN

MOLECULAR BIOLOGIST. The Urology Re-search Laboratory of UMDNJ-New Jersey MedicalSchool seeks applicants for a postdoctoral/research asso-ciate position available immediately to characterizecloned retinoid-responsive genes in neuroblastoma cells.Candidates must have a Ph.D. and several years ofdocumented experience in eukaryotic expression vectors,DNA cloning/sequencing. Background m biochemistry,cell/molecular biology desirable. Salary commnensuratewith experience. Please send curriculum vitae and threeletters of recommendation to: Alan K. Hall, Ph.D.,Director, Urology Research Laboratory, UniversityofMedicine and Dentistry ofNew Jersey-New JerseyMedical School, 185 South Orange Avenue, Newark,NJ 07103-2757. The UMDNJ is an Afirmative Action!Equal Employment Opportunity Employer M/F/H/V.

MOLECULAR IMMUNOLOGISTCandidates are sought at the assistant or associate

professor level, tenured or tenure-track, to undertakeresearch using molecular approaches to immunology.Candidates are expected to establish a vigorous researchprogram and participate in graduate student education.The closing date for receipt of inquiries is 1 Augst1989. Please send curriculum vitae and names of threereferences to: Search Comnmittee, Department of Pa-thology and Laboratory Medicine, 709 WoodruffMemorial Building, Emory University School ofMedicine, Atlanta, GA 30322. Emory University is anEqual Opportunity/Afirmative Action Employer.

NEUROCHEMISTRY SPECIALIST-Researchteams seek candidates with an M.D., Ph.D. in chemistryor equivalent and strong backgrounds in neuroscienceand demonstrated expertise in measurement of neuro-chemical and drugs in brain and biological fluids fromanimals and man. Expertise in HPLC, RIA, chromato-graphic techniques and the measurement ofplasma levelsof tacrine and physostigmine required. Send resume to:V. Haroutunian, Ph.D., Director, Basic and Labora-tory Sciences, Department of Psychiatry, Box 1239,Mount Sinai School of Medicine, Onc Gustave L.Levy Place, New York, NY 10029-6574. An EqualOpportunity Employer.

NEUROTRAUMA RESEARCH LABORATORYDIRECTOR SOUGHT

The Department of Neurological Surgery at the Uni-versity of California San Francisco (UCSF) and theNeurosurgery Service at the San Francisco General Hos-pital (SFGH) are seeking a qualified candidate to directresearch efforts at the Laboratory for Neural Injury at theSFGH. Current and recent research have examined mod-els of traumatic brain injury and focal cerebral ischemiaand their treatment. Future investigations will includeexamination ofmechanisms ofprogressive cellular injury,in vivo and in vitro, and evaluate possible methods of cellprotection. The candidate should have a background inbasic and/or applied research in brain injury and beprepared to conduct independent research as well asdirect the research efforts of a variety of medical studentsand neurosurgical residents and fellows in this area.Existing grant support would be helpful but not essentialfor the position, but it is anticipated that the director willsecure extramural support within several years. Interestedapplicants should send curriculum vitae to: Lawrence H.Pitts, M.D., Department of Neurological Surgery,UCSF, San Francisco, CA 94143-0112. UCSF is anEqual Opportunity Employer. Women and minorities are en-couraged to apply.

POSTDOCTORAL FELLOWSHIP-Postdoctor-al fellowship available immediately for an individual toundertake research with a project investigating the struc-ture and regulation of human glutamate dehydrogenaseand its involvement in deurodegenerative disorders. Po-tential candidates require a strong background in thefield of protein purification and biochemistry and/orgene cloning. Salary on the scale of $20,000 to $25,000per annum plus benefits commensurate with qualifica-tions. Location: New York City. Applications, includingcurriculum vitae, should be sent to: Dr. Andrew Plaita-kis, Neurology Department, Box 1137, Mount SinaiSchool ofMedicine, One Gustave L. Levy Place, NewYork, NY 10029-6574. Telephone: 212-241-7310.An Equal Opportunity Employer.

NUTRITION POSITIONSRutgers-The State University of New Jersey, invites

applications for two tenure-track positions in the newlyformed Department of Nutritional Sciences. Position 1,Assistant professor level, requires earned Ph.D./R.D. orM.D. and expertise in clinical nutrition. Position 2,associate/full professor level, requires earned doctorateand expertise in psychosocial aspects of nutrition, e.g.,psychosocial determinants of eatmg or nutritional impli-cations of diet on human behavior and development.Responsibilities for both positions include establishingand maintaining nationally recognized research programsin areas of expertise, teaching, and other universityservice. Deadline for both positions is 15 July 1989 oruntil suitable candidates are found. Send curriculumvitae, three letters of recommendation, transcripts, and astatement of research and teaching interests to: Dr.Adria R. Sherman, Department of Nutritional Sci-ences, 123 Davison Hall, Cook College/DouglassCampus, Rutgers University, New Brmanswick, NJ08903. An Afirmative Action/Equal Opportunity Employer.

PHYSICAL SCIENCES EDITORTo publish journals in physical and applied sciences.

Requires advanced degree, some publishing and/or relat-ed experience in an industry environment. Resume plussalary requirements to: Personnel, Elsevier SciencePublishing Company, 655 Avenue of the Americas,New York, NY 10010. Equal Opportunity Employer.

POSTDOCTORAL FELLOW for research on in-tracellular regulation and characterization of kidneytransport systems using membrane vesicles, culturedcells, photoaffinity labels, and other biochemical tech-niques. Previous experience in renal physiology or mem-brane biochemistry, and interest in cell physiology wouldbe useful. Available summer/fall of 1989. Send curricu-lum vitae and names of two references to: Dr. StephenA. Kempson, Department of Physiology and Bio-physics, Indiana University School of Medicine, 635Bamhi Drive, Indianapolis, IN 46223. An EqualOpportunity/Afirmative Action Employer.

POSTDOCTORALFELLOWSHIP POSMIION

Postdoctoral Fellowship position available in the De-partment of Surgery, UMDNJ-Robert Wood Johnson

edical School. Individual will work on focused projectinvolving in vitro models of ductal carcinoma invasionand mechanisms of breast tumor metastasis. Applicantshould have biochemistry and/or molecular biology expe-rience. Initial appointment for 2 years with competitivesalary and benefits. Respond immediately with curricu-lum vitae statement of experience and interests, andnames and telephone numbers of three references to: Dr.Fredika M. Robertson, Director, Surgical Immunolo-gyLaboratory, Department of Surgery, University ofMedicne and Dentistry ofNew Jersey-Robert WoodJohnson Medical School, 1 Robert Wood JohnsonPlace, CN 19, New Bnlnswick, NJ 08903-0019. TheUMDNJ is an Affirmative Action/Equal Employment Oppor-tunity Employer. M/F/H/V.

POSTDOCTORAL POSMIION available to studymotile behavior of lung macrophages and their role inlung's host defense and bacterial clearance. Research willbe directed at molecular events involved in cell motility.Experimental approach will include time-lapse videonicroscopy coupled with computer modeling to studymotile properties. Candidate should have Ph.D. or M.D.and experience in cell biology. Send curriculum vitae to:Ronald P. Daniele, M.D., 807 East Gates Building,Hospital of The University of Pennsylvania, 3400Spruce Street, Philadelphia, PA 19104-4283. EqualOpportunity Employer.

POSTDOCTORAL POSITION available immedi-ately to study developmentally regulated penicillin-bind-ing proteins in Bacillus subtilis. Experience in molecularbiology desired. Send curriculum vitae and names ofthree references to: Dr. C. Buchanan, Department ofBiological Sciences, Southern Methodist University,Dallas, TX 75275. Equal Opportunity/Affirmative ActionEmployer.

POSTDOCTORAL POSITION. Available imme-diately to study B cell development and Ig gene expres-sion in autoimmune prone mice. Experience in ceflularand molecular immunology desirable. Send curriculumvitae and arrange to have four letters of reference sentto: Dr. Judy Teale, Department of Microbiolog, Uni-versity of Texas Health Science Center, 7703 FloydCurl Drive, San Antonio, TX 78284-7758. TheUTHSCSA is an Affirmative Action/Equal OpportunityEmployer.

UNIVERSITY OF MARYLANDLABORATORY FOR PLASMA RESEARCHA POSTDOCTORAL POSITION in the experi-

mental plasma physics group is expected to be availablein November 1989, subject to funding, for work onfusion confinement experiments. Knowledge of magnet-ic fusion concepts and relevant diagnostics is desired. Formore inforrnation contact: Drs. A. W. DeSilva or G. C.Goldenbaum, Laboratory for Plasma Research, Uni-versity ofMaryland, CoLlege Park,MD 20742-3511.Telephone: 301454-3516.

The University ofMaryland is an Equal Opportunity!Affirmative Action Employer.

POSTDOCTORAL POSITION: We have a posi-tion available immediately to work in the field of theapplications of clinical NMR spectroscopy to the studyof patients with liver metastases arising from colorectalcarcinoma. This study involves the application of anintegrated MRI/multinuclear MRS (1-H, 19-F, and 31-P) approach to monitor patients receiving chemotherapybased on the continuous infusion of 5-FU through animplanted pump. The applicant is expected to interactwith an interdisciplinary team of clinicians and basicscientists. Facilities include two 1.5-T whole body MRscanners and access to a variety of high-resolution NMRspectrometers. A Ph.D. in NMR spectroscopy or MRimaging is preferred. Please apply to: Dr. R. E. Len-kinski, Department of Radiology, Hospital of theUniversity ofPennsylvania, 3400 Spruce Street, Phil-adelphia, PA 19104. The University ofPennsylvania is anEqual Opportunity/Afirmative Action Employer. Qualifiedfemale and minority candidates are encouraged to apply.

POSTDOCTORAL POSITION available immedi-ately to study the organization, expression, and regula-tion of murme class I MHC genes. Studies will alsoinvolve characterization of proteins encoded by thesegenes. Only U.S. citizens orpermament residents are eligiblefor this position.

Send curriculum vitae and names of three referencesto: Dr. S. W. Hunt, University of North Carolina-Chapel Hill, 932 FLOB CB# 7280, Chapel Hill, NC27599-7280.An Equal Opportunity/Affirmative Action Employer.

POSTDOCTORAL POSITION IN MOLECU-LAR GENETICS. Immediate opening in our Molecu-lar Genetics Laboratory (Dr. James Hixson) for anindividual with expertise in molecular methods andinterest in gene mapping in nonhuman primates. Thisgenome mapping project will require isolation of probes(and use ofthuman probes) to detect DNA polymor-phisms for linkage analyses in large baboon families(n = 1500). Please send resume, statement of researchinterests, and names, addresses, and telephone numbersof three references to: Personnel Director (045),Southwest Foundation for Biomedical Research,P.O. Box 28147, San Antonio, TX 78284. EqualOpportunity Employer M/F.

POSTDOCTORAL POSITION, MOLECULARBIOLOGIST available to study the virulence propertiesof Entamoeba histolytica. Projects will involve cloning aunique surface antigen of pathogenic strains and viru-lence-related proteinases. Applicants should have experi-ence with standard molecular biology techniques. Famil-iarity with DNA sequencing and eukaryotic geneticsdesirable. Send curriculum vitae with names and address-es of three references to: Dr. S. L. Reed, Division ofInfectious Diseases, H-811F, UCSD Medical Center,225 West Dickinson Street, San Diego, CA 92103.

SCIENCE, VOL. 24S94

POSITIONS OPEN POSITIONS OPEN

Abbott Laboratories' Diagnostics Division holds an undisputed leadership position in the development of medical diagnosticsproducts. Our extensive technical resources create a superior environment for those who would like to make a significant personaland professional commitment.

BIOCHEMISTainical Chemistry AssayDevelopment/Support

Joining our Technical Product Development Group, theselected candidate will be responsible for technicaltroubleshooting and product and process development for ourclinical chemistry product line. The position requires the abilityto quickly evaluate and resolve technical problems relating tothe manufacturing, development, testing and field performanceof diagnostic tests. Excellent interpersonal skills are requiredas well as an M.S. and three years experience or Ph.D. inBiochemistry, Physioloqical Chemistry, or Life Sciences.Postdoctoral and supervisory experience are desired. Job #9RT

BIOCHEMIST/

IMMUNOCHEMISTCardiovascular/Endocrinology

We currently seek scientists to function as project managersfor the development of Diagnostic Assays for physiologicalanalytes. The preferred candidates will possess a Ph.D. inBiochemistq or Clinical Chemistry; postdoctoral or industrialexperience is preferred. Research background should includeprotein biochemistry, immunochemistry, ligand binding assays,and immunoassay techniques. Familiarity with endocrinologyand/or cardiovascular research is desirable.Job #93Y.

Located in an attractive suburban area approximately 30 miles north of Chicago, Abbott Laboratories provides a competitivecompensation and benefits package includina profit sharing. For consideration, Dlease send your resume with salary history to:Keith Allen, Corporate Placement, Abbott Laboratories, 1 Abbott Park Road, Abbott Park, IL 60064.(To facilitate handling your resume, please indicate Job # on your cover letter or resume.)Abbott is an Affirmative Action Employer.

Meeting Bound?ABBOTT LABORATORIES

Please bring your resume and look for us at the Protein Halith CSociety and American Association for Clinical Chemistry

HeaWtr are

Conventions later this summer. Worldwide____ 1888-1989

THE

SCiENCERECRUITMENT

"FOUR DAY CLOSE"NOW YOU CAN SEE YOUR AD IN SCIENCE

FOUR DAYS AFTER SUBMISSIONScientific Recruiters can now advertise positions almost assoon as the need arises. Instead of reserving space a month ormore in advance, you can now place your ad four days beforethe magazine mailing date. SViECiE is mailed on the cover date.Film (right-reading, emulsion face down) or full camera readyart and insertion order must reach: SCiENtC, Short Close Desk,1515 Broadway, New York, NY 10036 by NOON Mondays(except for legal holidays when material must reach New Yorkby Noon Fridays). Because space is limited, the four-day closepage will be reserved on a first-come, first-served basis, at a15% premium. 1/4 and 1/2 page ads only.Now you don't have to wait to find the researchers you needimmediately, nor must you advertise in a Sunday paper thatpans a lot of sand, but not much gold. Scientific employersknow that SCiENCE ads fill the job better. Now they fill it fastertoo.You can call it "INSTANT RECRUITMENT."For further information, telephone Ed. Keller, Recruitment Ad-vertising Manager, or Donna Rivera, Production Manager atSCiENCE: 212-730-1050, or write to: SCiENCE, 1515 Broadway,NY, NY 10036.

CURRENT DISTRIBUTION 160,000

CORNELL UNIVERSITY MEDICAL COLLEGECORNELL. UNIVERSITY invites applications fromqualified candidates for the position of Chairman ofthe Department of Pharmacology at CORNELLUNIVERSITY MEDICAL COLLEGE in New York City.The Chairman of Pharmacology will head an activedepartment with research strength in Biochemical,Physiological and Clinical Pharmacology. In addi-tion to research, the department is responsible forteaching of Pharmacology to medical and graduatestudents. Candidates must have a Ph.D or M.D.Degree, must be recognized for excellence inbiomedical research and scientific leadership andhave extensive experience in teaching at amedical school.Applicants should submit a current C.V.which includes a list of publications to:Erich E. Windhager, M.D. ChairmanSearch Committee Department of Physiology

-I I,

1300 York Avenue, New York, New York 10021EEO/AA/M/FIHN

I

II%a

POSITIONS OPEN

POSTDOCTORAL POSMON INFETAL PHYSIOLOGY/ENDOCRINOLOGYAvailable January 1990, position supported by

USPHS-NIH Training Grant. Various aspects of fetalendocrine and cardiovascular regulation are under investi-gation. These include: development ofthe hypothalamic-pituitary-adrenal axis, the hormonal and neuroendocrincregulation ofthe onset oflabor, biochemical basis of fetalcardiovascular-endocrine interactions and responses tolong-term hypoxia, and placental ion transport. Studiesinvolve both m vitro and in vivo approaches.

Applicants shouldhave a strong background inendo-crinology, physiology, cell biology, or biochemistry.Send curriculum vitae and the names of three referencesto: Dr. Lawrence D. Longo, Division of PerinatalBiology, Department of Physiology, School ofMedi-cne, Loma Linda University, Loma Linda, CA92350. Equal Opportunity Employer.

POSTDOCTORAL POSITIONMOLECULAR BASIS OF

BACTERIAL PATHOGENESISA postdoctoral position is available to work on the

molecular basis of the interaction of Legionella pneumophi-la with human phagocytic cells. L. pneumophila entcrsmacrophages and survives by inhibition of phagosome-lysosome fusion. The organism then replicates intracellu-larly and destroys the host cell. Research will focus on theregulation of Legionella genes during macrophage infec-tion and the molecular basis for intracellular survival andgrowth. Applicants must have prior training in bacterialgenetics. Salary will be commensurate with experience.Please send curriculum vitae and arrange for three lettersof reference to be sent to: Dr. Howard A. Shuman,Department of Microbiology, College of Physicians& Surgeons, Columbia University, 701 West 168thStreet, New York, NY 10032.

Columbia University is an Equal Opportunity/AfirmativeAction Employer.

POSTDOCTORAL POSMONS IN MEDICI-NAL CHIEMISTRY AND PHARMACOLOGYavailable 1 August 1989 for individuals interested in thestudy of (i) protein/nudeic acid interactions during DNApolymerization, and (ii) neuropeptide SAR and pharma-cology. Experience in protein and nudeotide chemistryor cardiovascular pharmacology preferred but not re-quired. Send currculum vitae and three letters of recom-mendation to: Dr. M. B. Douphty, Department ofMedicinal Chemistry, University of Kansas, Law-rence, KS 66045-2506. Equal Opportunity Employer/Affirmative Action.

POSTIDOCTORAIJRESEARCH ASSOCIATEPosition available to study the effects and the mecha-

nisms of actions of neuropeptides and hormones usingcell models. Background in cell biology, pharmacology orbiochemistry desirable. Please send curriculum vitae, abrief statement of research interest and the names ofthree references to: Dr. Kazuhiko Tatemoto, Depart-ment of Psychiatrv and Behavioral Sciences, StanfordUniversity School ofMedicine, Stanford, CA 94305.

POSTDOCTORAL RESEARCH ASSOCIATEpositions available to study regulation ofgene expressionas applied to macrophage differentiation and maturation.Research focuses on the role oflymphokines and eicosan-oids in macrophage activation. Mofccular biology experi-ence is desirable. Send curriculum vitae and statement ofresearch interests to: Dr. Kent Erickson, DepartmentofHuman Anatomy, University of California, Schoolof Medicine, Davis, CA 95616.

POSTDOCTORAL RESEARCH ASSOCIATEpositions available for recent Ph.D. to work on severalaspects of protein kinase C system: (i) cardiac contractileproteins and functional consequence of phosphorylationof troponin subunits, (ii) regulation of leukemia andneuronal cell growth and differentiation, and (iii) devel-opment of activators and inhibitors of protein kinase Cfor biochemical, biophysical and preclinical pharmacolo-g studies. Send application and curriculum vitae to: Dr.

F. Kuo, Department of Pharmacology, EmoryUniversity School of Medicine, Atlanta, GiA 30322.

Emory University is an Equal Opportunity Employer.

TWO POSTDOCTORAIRESEARCH ASSO-CIATE POSMONS are immediately available for:Position 1 studying synthesis of mRNA and protein inwinter cereals undergoing adaptation to low non-freez-ing temperature; the preferred applicant should haveexpertise with mRNA purification, in vitro translationand/or cDNA cloning. Position 2 studying changes incell membrane receptors and metabolism during devel-opment and response to environmental stimuli by avariety ofbiochemical techniques induding flow cytome-try detection of tagged probes; this applicant should haveexpertise in cell and molecular biology/immunology us-ing fluorescent tagged probes. Flow cytometry experi-ence desirable. Starting salary is $24,000 per year. Annu-al appointment possible for 3-year period. Candidateswho have recenty obtained a relevant Ph.D. degree areencouraged to send curriculum vitae and names of threereferences to: Dr. David Hilderbrand, Head, Chemis-try Department, South Dakota State University,Brookings, SD 57007. Application deadline: 15 Au-gust 1989 or until filled. SDSU is an Equal OpportunityEmployer.

PROFESSOR PHARMACOGNOSY. The Univer-sity of Connecticut is seeking applications for an antici-pated tenure-track position, available 1 September 1989for a pharmacognosist (natural products chemist) to beappointed at the rank of associate or full professor.Preference will be given to individuals possessing thequalifications for and a willingness to assumne responsibil-ity as head of the section of Medicinal Chemistry andPharmnacoguosy. Applicants should have a Ph.D in phar-macognosy, orgamc chemistry or a cognate science, ademonstrated commitrnent to graduate and undergradu-ate education, and an established program of research.An undergraduate degree in pharmacy is desirable, butnot essential. Curriculum vitae, induding graduate tran-script, list of publications, summary of research supportand interest, and three letters ofrecommendation shouldbe mailed directly to: Professor J. M. Edwards, Sectionof Medicinal Chemistry and Pharmacognosy, Schoolof Pharmacy, U-92, University of Connecticut, 372Fairfield Road, Storrs, CT 06269-2092. The Universi-ty of Connecticut is an Affirmative Action/Equal OpportunityEmployer M/F. (Search #9A284).

QUANTITATIVE ECOLOGISTASSISTANT PROFESSOR

UNIVERSITY OF WASHINGTONThe Center for Quantitative Science in Forestry, Fish-

eries and Wildlife and the School of Fisheries inviteapplications for a tenure-track, 9-month teaching andresearch appointment, beginning on or after 1 October1989. The applicant shou[d be experienced in mathemat-ical modeling of ecological and natural resource process-es. The ideal candidate might have a Master's degree in abiological subject and an earned doctorate in a mathe-matical subject, or vice versa.Teaching wil be three courses per year, primarily to

graduate students in Fisheries and the BiomathematicsProgram in Quantitative Ecology and Resource Manage-ment. The person selected will also supervise graduatestudent research, but will have broad latitude in develop-ing a research program.

Please send a letter stating academic interests, alongwith curriculum vitae, reprints of recent papers (up tothree), and names, addresses, and telephone numbers offour references, by 15 August 1989 to:Stephen B. Mathews, Chairman ofSearch Committee

Center for Quantitative ScienceUniversity of Washington, HR-20

Seattlc, WA 98195Telephone: 206-543-4458 or 206-543-1191

The University of Washington is an Equal Opportunity/Affirmative Action Employer.

RESEARCH SCIENTIST: Position for a Ph.D. inchemistry/crystallography to investigate the electroniccharacteristics of reactants, products, and intermnediatesin biotin-mediated reactions. Candidate must havestrong background in experimental charge-densitv anal-ysis by x-ray diffraction, including faniaty with vari-ous multipolar expansion models and anharmonic ther-mal motion moders, and experience in low temperaturex-ray diffraction. Salary: $24,000 to $27,000 per year.Send r6sumi to: Dr. George DeTitta, Medical Foun-dationofBuffalo, 73 High Street, Buffalo, NY 14203.

PROJECT LEADER/SCIENTIST POSITION.The Forestry Sciences Laboratory in Delaware, Ohio,will announce shortly a vacancy for a permanent, full-time Project Leader/Scientist to lead a unit conductingresearch on the application of biotechnology to forestinsect and disease research and management. Applicantswith a strong background in biochemistry/molecularbiology are invited to apply for the position, which willbe at the GM-14/15 leve.

Persons wishing to apply for the position should sendtheir name and address to: Ms. Carol Cowles, USDA-Forest Service, 359 Main Road, Delaware, OH43015. When the position is formally announced, a copyof the announcement will be sent to you. For informa-tion and assistance in a pplying, please contact: Ms.Cowles, at the above address or by telephone at 614-369-4476.

RESEARCH MANAGERThe Regional Primate Research Center of the Univer-

sity of Washington seeks a research manager to adminis-ter and participate in biomedical research projects cen-tered at its Primate Field Station in Medical Lake,Washington. The Research Manager will work withresearch investigators at the University of Washington,the NIH and biotechnology firms to plan and developprotocols, budgets and agreements for projects ofmutualmterest; will supervise the research, and will participatein the publication of findings. A doctoral degree in thebiological, veterinary, or medical sciences with a mini-mum of 5 years of independent research and 2 years ofsupervisory experience in immunology, virology, bio-technology, or a related area required. Previous experi-ence with biomedical research in private industry desir-able. Experience with nonhuman primate models desir-able, but not essential. Salary to $55,056 depending onexperience. Please send curriculum vitae and names ofthree references by 28 July 1989 to:

Dr. Darrell Williams, Assistant DirectorRegional Primate Research Center

Primate Field StationMedical Lake, WA 99022

The University of Washington is an Affirmative ActioniEqual Opportunity Employer.

GEORGETOWN UNIVERSITY HOSPITALWASHINGTON, D.C.RESEARCH POSITION

DIRECTOR OF PEDIATRIC CRITICALCARE RESEARCH PROGRAM

To lead bench and clinical research of immune media-tors and their role in critical illness in children. Must haveminimum of 5 years of experience in research in the fieldof immune mediators and cytokines. Must be Board-eligible/Board-certified in Pediatric Critical Care. Candi-date must have expertise in laboratory animal research, intechniques in cellular immunology including cytotoxicityassays and cytokine assays, and in the design and controlof clinical research. Salary commensurate with qualifica-tions. Send curriculum vitae, reprints, and names ofreferences to: Owen Rennert, M.D., Professor andChairman, Department of Pediatrics, GeorgetownUnivcrsit Children's Medical Center, 3800 Reser-voir Road, N.W., Washington, DC 20007.

RESEARCH SCIENTIST POSITIONOTTAWA REGIONAL CANCER CENTREThe Ottawa Regional Cancer Centre has an extensive

cancer research program encompassing aspects of thecancer problem from bench to bedside. These includemolecular biology, cell and animal models, physics, andclinical trials. The position available is for a biophysicistto work in the area of cellular and animal biology. Crossappointments at two universities are possibke and astrong graduate student program provides a stimulatingresearch and academic environment.The candidate should have a Ph.D. degree or equiva-

lent, experience in working with cells in culture, animalsystems, and a wide range of standard laboratory equip-ment and techniques. Assets are: Experience in molecularbiology, good written and verbal communication skills,publications and successful grantsmanship, degree inphysics. Please send resume to: Dr. G. P. Raaphorst,Head of Medical Physics, Ottawa Regional CancerCentre, 190 Melrose Avenue, Ottawa, Ontario, Cana-da KlC 4K7.

SCIENCE, VOL. 24596

POSITIONS OPEN POSITIONS OPEN

NATIONAL INSTITUTESOF HEALTH

MEDICAL STAFF FELLOWSHIP

The National Institute on Aging isseeking Medical Staff Fellows to devel-op independent research programs invascular cell biology and diseasesrelated to aging. Studies will utilizecellular and molecular biology andhave application to changes in bloodvessels in aging and disease. Theinitial appointment is for a startingsalary range of $28,000 to $52,825depending on background andexperience. Candidates must have aM.D. degree or its equivalent and bea U.S. citizen or permanent resident.Send curriculum vitae and statementof research interests to:

Dr. George R. MartinScientific Director, NIA

Gerontology Research Center4940 Eastern Avenue

Baltimore, Maryland 21224

?'k I%V'S

NIH IS AN EQUAL OPPORTUNITY EMPLOYER

THE

The Biogen story starts with our strategic focus on humantherapeutics. From AIDS and anti-inflammation to selected cancer

markets, we continue to enjoy a leadership position in the field of biotech-nology. Among our latest breakthroughs is Receptin , an AIDS therapy now

in human clinical trials. Our West German affiliate is marketing gamma interferonfor the treatment of rheumatoid arthritis. In fact, gamma interferon is the fourth marketed drug thatBiogen has played a major role in developing. With 11 years in the industry, Biogen continues todisplay the maturity and innovation needed to reach its ultimate goal of becoming a fully-inte-grated pharmaceutical company.

Protein ChemistAs a member of our Process Development department, your responsibilities will include designing newprocesses for protein purification; developing large-scale purifications of pharmaceutical-grade proteins; in-vestigating formulations; and conducting process validation.A Ph.D. with emphasis in Protein Purification, Protein Chemistry, or Physical Chemistry of Protein is re-quired. Post-Doctoral or industry experience is preferred, especially in the practical aspects of proteinpurification, refolding or characterization.The outstanding Biogen benefits package includes fuilly-paid life, medical, dental and disability insurance.A 401k savings plan with a company-matching provision along with company-paid pension. 100 percenttuition reimbursement for as many as 4 courses a year. And 10 weeks' paid maternity leave. Plus a lot oflittle things that really add up - like our credit union, on-site aerobics and relocation assistance.

To apply for this immediate opening, send your resume to Biogen, Inc., Ref. SPC77, 14Cambridge Center, Cambridge, MA 02142. Biogen is an Equal Opportunity Employer.

BQCENBIOLOGICAL OCEANOGRAPHY/

REMOTE SENSING

Faculty PositionThe Institute of Marine Science, University ofAlaska Fairbanks is seeking an outstanding scien-tist for a tenure track position in teaching andresearch in the area of biological oceanographywith specialization in remote sensing techniques.The position will be filled at the Assistant Professorlevel or above depending on background andexperience. The successful applicant will be ex-pected to develop a vigorous research program inbiological oceanography oriented toward polar wa-ters based on remote sensing methods, as well asparticipate in teaching and guidance of graduatestudents. The University of Alaska Fairbanks isdeveloping a major remote sensing facility that willoffer new opportunities in the area of research.The Institute of Marine Science has a faculty of 24with a graduate enrollment of 40-50 students. Thefaculty are involved in a variety of research pro-grams emphasizing Arctic and high latitude seas.

Applicants should send a summary of researchinterests with a curriculum vitae and the names,addresses, and phone numbers of three refer-ences to:

C. Peter McRoyChair, Remote Sensing Search Committeec/o Director's OfficeInstitute of Marine ScienceUniversity of Alaska FairbanksFairbanks, AK 99776-1080

Closing date for applications is 31 July 1989.Applications of finalists may be subject to publicdisclosure. Persons hired must comply with thenew employment provisions of the Federal Immi-gration Reporting Act. The University of Alaska isan Equal Opportunity/Affirmative Action Employerand educational institution.

Positions inApplied Biotechnology

Pfizer, a U.S. based multinational pharmaceutical company, is seeking qualifiedscientists to expand a recently established Applied Biotechnology research groupat its Central Research facility in Groton, Connecticut. We are looking forindividuals with strong credentials in the areas of immunology and cellularreceptors. You should have the desire and ability to develop novel assaytechnology and should be capable of applying this technology to the discovery ofnew therapeutic agents.

Your qualifications should include a PhD degree and at least two years postdoc-toral training. Experience in one or more of the following areas, monoclonalantibodies, immunological detection techniques, pharmacology, molecular biol-ogy, or natural product screening is also desirable. You will be expected toestablish and maintain collaborations with specific project teams in a number oftherapeutic areas throughout our discovery research operations including sites inEurope and Japan.There are also positions available at the BS or MS level. These individuals shouldhave one to three years of experience in at least one of the above areas.

Pfizer offers a stimulating scientific research environment, a competitive compen-sation and benefits package along with relocation assistance to this southeasternConnecticut shoreline community. Please send a resume, a description of your re-search experience, and names of three references to: Jerry K. Larson, PhD,Assistant Director, Employee Resources, Research Personnel, Pfizer CentralResearch, Eastem Point Road, Groton, CT 06340. An equal opportunity employer.

POSITIONS OPEN

RESEARCH ASSOCIATE, Ph.D.-Molecular bi-ology and biochemistry to study regulation ofaminopep-tidase expression in vitro and in vivo, as well as uponaging and/or transformation. Available immediately.Please send resume, list of experience, and three letters ofreference to: Dr. Allen Taylor, Director, Laboratoryfor Nutrition and Cataract Research, Human Nutri-tion Research Center on Aging at Tufts University,711 Washington Street, Boston, MA 02111. Afirma-tive Action/Equal Opportunity Employer.

MARIE CURIE RESEARCH INSTITUTESTAFF POSMONS IN CELLAND MOLECULAR BIOLOGY

Independent staff positions are available for scientistswith at least 2 years ofpostdoctoral experience. Researchinterests can be within a broad range of topics indudingcell and molecular biology of development, differcntia-tion, and/or oncogenesis. These posts are core-funded,and the laboratones well-resourced and equipped forcontemporary molecular and/or cellular techniques. Suc-cessful candidates will be expected to develop their ownresearch group. Send curriculum vitae plus a shortstatement of research interests to: G. Currie (or tele-phone him on (0)883 722306) at the Marie CurieResearch Institute, The Chart, Oxted, Surrey, RH8OTL, U.K.

A STAFF SCIENTIST position is available to studythe virological and immunological mechanisms of HIVinfection as well as vaccine development in chimpanzees.A Ph.D., M.D., or D.V.M. is required with appropriateresearch experience and laboratory management in theareas of HIV cellular immunity, virology, or molecularbiology. The program is under the direction ofJorg W.Eichberg, D.V.M., Ph.D. Annual salary ranges up to$40,000, dependent upon relative experience. Pleasesend curriculum vitae with names, addresses, and tekl-phone numbers of three references to arrive by 1 August1989. Address material to: Personncl Director (040),Southwest Foundation for Biomedical Research,P.O. Box 28147, San Antonio, TX 78284. EqualOpportunity Employer M/F.

STATISTICIAN-Insurance company has an out-standing opportunity in the Corporate Research Divi-sion. Seeking an individual to develop and implementquantitative analysis projects in areas such as risk selec-nlon and experimental design. Training at the Master's orPh.D. level, 2 to 5 years ofexperience m applied statisticsor operations research, and strong technical and commu-nications skills are required. Position offers challengingassignments in a highly professional environment, acompetitive salary, and comprehensive benefits. To ap-ply, please contact: Margarct MacKay, The TravelersCompanies, Corporate Rec Division-6PB,One Tower Square, Hartord, CT 06183-7200.Tclephonc: 203-277-0259.

Rutgers University: The Camden chemistry facultyanticipates the appointent of a SYNTHETIC OR-GANIC CHEMIST with a commitment to tcachingand the potential for significant research accomplishmentfor 1 July 1990 to fill a vacancy created by retirement.Further information can bc obtained from: S. A. Katz,Rutgers University, Camden, NJ 08102. Rutgers Uni-versity is an Equal Opportunity/Affirmative Action Employer.

VASCULAR CELL BIOPHYSICSApplications are invited for a tenure-track faculty

position at the ASSISTANT PROFESSOR level in theDepartment of Biophysics. Candidates must havc aPh.D. in an appropriate discipline and at least 2 years ofpostdoctoral expenence. The individual will be expectedto establish a vigorous and independent research pro-gram in somc aspect of vascular smooth muscle orcndothelial cell biophysics/physiology which will com-plement cxisting programs in membrane transport, ccllstructure and mechanics, microvascular control and mi-crocirculatory hemodynamics. Curriculum vitae, state-ment of research interests and names of three referencesshould be sent to:

Dr. Paul La Ceile, ChirmanDeprqtment of BiophysiFsUniversity of RochesterRochester, NY 14642

An Equal Opportunity Employer MIF.

SCIENTIST to join the research faculty of the De-partment of Ancsthesiology at Duke University. Appli-cant must have minimum of 7 years of research experi-ence, 3 years in anesthesiology. Applicant must be skilledin cardiovascular biochemistry, biophysics, computers,and statistics. Ph.D. degree in biochemistry/pharmacolo-$y preferred. Appointment and salary will be at Associatem the Department of Anesthesiology level. Duke is anEqual Opportunity/Afirmative Action Employer. Send cur-riculum vitae and if not U.S. citizen, please indicate visastatus. Reply: Box 101, SCIENCE.

AWARDS

AMERICAN EPILEPSY SOCIETYAWARDS PROGRAM

The American Epilepsy Society announces a newannual Awards Program designed to encourage andreward clinical and basic science investigators whoseresearch contributes importantly to understanding andconquering childhood-onset epilepsy.Category 1 Awards: Two Annual Awards of

$150,000 each will be made to senior individuals whohave a distinguished history ofresearch achievements andprofessional excellence related to pediatric aspects ofepilepsy. One award will go to a clinical investigator andthe other to a basic scientist.Category 2 Awards: Three Annual Awards of

$50,000 each will be made to individuals whose researchhold promise of leading to important advances in theunde tag, diagnosis and treatment of childhood-onset seizures and epilepsy. At least one award in thiscategory will go to a clinical investigator.

Candidates for the American Epilepsy Society Awardsare nominated by their peers. The American EpilepsySociety has the sole responsibility for selection of re-cipients. Nomination forms are available from the Ameri-can Epilepsy Society. Deadline for completed nomina-tions us 1 October 1989. Awards will be announced atthe annual meeting of the American Epilepsy Society inBoston, 2 to 7 December 1989.

Contact: The American E piles Society AwardsProgram, AES Executive Ofice, 179 Allyn Street,Suite 304, Hartford, CT 06103-1488. Telephone:203-246-6566.The American Epilepsy Society Awards Program has

been made possible by funds generously provided by theMilken Family Medical Foundation.

TRAINING PROGRAM

UNIVERSITY OF VIRGINIADEVELOPMENTAL BIOLOGY

TRAINING PROGRAMFunding is available to support qualified individuals

for pre- and postdoctoral training in developmentalbiology. This program emphasizes training in modem,interdisciplinary approaches to the study ofdevelopmen-tal processes.

Paul Adler, MorphogenesisGary Balian, Cellular MatrixAnn Beyer, DifferentiationRobert Bloodood, DifferentiationClaire Cronmnler, Sex DeterminationDoug Desimone, Cell InteractionsPeter Dierks, DifferentiationCharles Emerson, Lineage DeterminationMariln Fisher, Neural evDlopmentRobert Grainger, Tissuc InductionJoha Herr, GametogenesisIrwin Konigsberg, DifferentiationCharles Litte, Cell InteractionsSally Moody, EmbryogenesisOscar Miller, CytogeneticsLionel Rebhun, Mototic RegulationOswald Steward, Neural DevelopmentJeremy Tuttle, Neural DevelopmentMike Wormington, Embryogenesis

Theodore Wright, Developmental GeneticsFor more information, contact: Dr. Charles Emer-

son, Director, Dcvelopmental Biology Training Pro-gram, Department ofBiology, University ofVirginia,Charlottesville, VA 22901, or tclephone 804-924-7067.

UVA is an Equal Opportunity/Affirmative Action Institution.

TENURED OR TENURE-TRACKFACULTY POSMONS

Tenured or tenure-track faculty positions are availablein a newly established Program in Molecular Medicine.This interdisciplinary program currently includes ninefaculty research programs in complementary fields ofbiomedical science and occupies 40,000 square feet ofresearch space in a newly constructed building. TheMedical Center is committed to recruiting and support-ing scientists of the highest quality in an outstandingresearch environment. Research areas currently beingexpanded indude:

1. Molecular virology/retroviruses2. Molecular immunology3. Tumor biology/oncogenes4. Malacronocular strucrex-ray a g y/NMR5. Cellular physiology/signal transductionThere is particular interest in candidates using contem-

porary methodologies, e.g., transgenic animals. Appli-cants must have a Ph.D. or M.D. degree with demon-strated research productivity. A strong motivation to-ward creative research and ability to attract independentfunding is essential. Faculty rank and salary are negotia-ble. Applicants must submit curriculum vitae, summaryofresearch interests and names ofthree references to: Dr.Michael P. Czech, Director, or Dr. John L. Sullivan,Search Committee Chairman, Program in MolecularMedicinc, University of Massachusetts MedicalSchool, 55 Lake Avenue North, Worcester, MA01655.

An Equal Opportunity/Affirmative Aaion Employer.

SYMPOSIUM

NONINVASIVE TECHNIQUES INBIOLOGY AND MEDICINE

Lovelace Medical Foundation Annual Symposium, 14to 15 September 1989. A symposium dedicated tomagnetic resonance, video, acoustic and other biologicaland medical imaging techniques. Continuing MedicalEducation Units will be offered. For details and registra-tion information contact: Cathy Barboa, LovelaceMedical Foundation, Research Division-, 2425 Ridge-crest Drive, S.E., Albuquerquc, NM 87108. Tele-phone: 505-262-7560.

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