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Presentation of Persistent Company competencies in analytical instrumentation
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www.persistentsys.com
© 2012 Persistent Systems Ltd
Persistent’s expertise across multiple Analytical Instruments
© 2012 Persistent Systems Ltd 2
Our Expertise across multiple
Instruments
FC
GCLC
MS
CE
PCRNGS
Support
Driver
Devel
opm
ent
Regulatory
compliance
Bioinformatics
Dat
a M
anag
emen
t
Solu
tions
Our Expertise
Product Development
© 2012 Persistent Systems Ltd 3
Driver Development• Driver Portfolio management
(Development, Maintenance and versioning)
• Development of drivers, plug-in’s and custom solutions
• Single shop of device drivers for various instruments (Driver Central)
• Continuous Product Engineering (CPE)
Product Development • Automate data acquisition / signal
processing systems• Automated testing to speed up
validation• Research and clinical applications.
Instrument control software, primary ,secondary and tertiary analysis applications
• New application development or customize widely used open source sequence analysis tools to support specific analysis
Data Analysis and visualization• Comparative sequencing analysis for
SNP discovery and mutation detection
• Fully integrated base calling, sequence assembly, alignment, and sequence comparison tools
• Reusable parsing framework and components for biological data formats
• Implement visualization techniques for structured, unstructured and domain specific data sets
• Automatic data filtering and results reporting
• Data migration & integration services
• Integrate existing analysis tool to well established visualization tools
Regulatory Compliance• Developing generic solutions to
satisfy guidelines mandated by FDA
• Workflow automation by interfacing with various Chromatography Data Systems
• Develop applications that are 21CFR part 11, DQ, IQ, OQ, PV, GAMP, EU GMP Annex 11, HL7, HIPAA, LOINC, ANSI X12, ICD-9/10, DICOM compliant
• Usability engineered workflow designs to ease on compliance delivery
• Deliver compliance services at customer site
Bioinformatics Development of new algorithms for secondary
and tertiary analysis, implementation of published algorithms
Performance tuning of prototype algorithms/ tools
Algorithm/Functional Testing
Performance & Computational Support• Performance optimizations in algorithms and
workflow tools • Enablement of workflow on public/private cloud
Support
Driver
Developm
ent R
egul
ator
y
com
plia
nce
Bioinformatics
Data Analysis and
visualizationProdu
ct
Devel
opm
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Instrumentation Offerings
© 2012 Persistent Systems Ltd 4
Instrumentation (Chemistry) Expertise
Gas ChromatographySample preparation, headspace, SPME, FID, ECD, TCD
Liquid ChromatographySample preparation, µ HPLC, UV, DAD, fraction collection
Domain ExpertsIn-depth knowledge of high-throughput laboratories needs
Global StrategiesLocalization and globalization of Software
Software DesignDesigning Ergonomic software using Agile methods
Mass spectrometryStrong expertise in Tuning, Mass locking, MS/MS, MSn, complex method edition
Product Development
Support
Driver
Developm
ent R
egul
ator
y
com
plia
nce
Bioinformatics
Data Analysis and
visualizationProdu
ct
Devel
opm
ent
© 2012 Persistent Systems Ltd 5
Flow Cytometer• Multicolor Flow Cytometry
Instrument• Flow Information System for Mining
Of Flow Cytometry Data• Rich tools for flow cytometer and
application setup, data acquisition, and analysis that help streamline flow cytometry workflow.
Instrumentation (Biology) Expertise
Real Time PCR• Developed software for multiple
generations of real time PCR instruments
• Primary and secondary Data collection and analysis software
• Application specific analysis software including pathogen detection, gene expression analysis software
Capillary Electrophoresis• End to end software development • Primary and secondary data analysis
tools for fragment and Sequencing data analysis.
• Next generation platform for Assay integration for clinical use
NGS• Developed Instrument Control
Software, • Applications Framework for NGS
data analysis primary, secondary and tertiary data analysis,
• Clinical application of NGS data • Cloud hosted solutions• Performance optimization of
algorithms and workflow tools
Product Development
Support
Driver
Developm
ent R
egul
ator
y
com
plia
nce
Bioinformatics
Data Analysis and
visualizationProdu
ct
Devel
opm
ent
© 2012 Persistent Systems Ltd 6
Platforms• Diamir Galaxie CDS• Varian Next Gen. GC/MS
CDS• Agilent OpenLAB• Bruker CompassCDS• Agilent Cerity
Drivers• 100+ developed• Varian, Agilent, PE, Thermo,
Waters, CTC, Kontron etc.• Native drivers, RC.net, ICF
integration• Continuous Product
Engineering (CPE)
Migration• CDS migration: Galaxie
OpenLAB
Our Experience
© 2012 Persistent Systems Ltd 7
Why Persistent?
100+Instrument Drivers developed
Years of experience of producing chromatography software for petro-chemical and pharmaceutical companies
In-house Laboratory for development & acceptance testing
Strong cross-disciplinary team – Computational Scientists, Molecular Biologists, Medicine, Bioinformatics, Instrumentation Specialists
20+
Agile Practices for software development improving both customer satisfaction and time to market
15+Years of experience in Instrument Driver development
© 2012 Persistent Systems Ltd 88© 2012 Persistent Systems Ltd
Contact Us
www.persistentsys.com
Sebastien RATTIER
R&D Manager for instrumentation
Persistent Systems France SAS+33.4.76.53.35.87
