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Peripheral Nervous SystemPeripheral Nervous System
Nerves outside the brainNerves outside the brain
Peripheral Nervous SystemPeripheral Nervous System StructuresStructures
Sensory receptorsSensory receptors– Mechanoreceptors (touch, pressure, vibration, and stretch)Mechanoreceptors (touch, pressure, vibration, and stretch)– Thermoreceptors (temperature changes)Thermoreceptors (temperature changes)– Photoreceptors (light energy)Photoreceptors (light energy)– Chemoreceptors (chemicals in solution)Chemoreceptors (chemicals in solution)
Nerves (cranial and spinal)Nerves (cranial and spinal)– Cordlike organ that is part of the PNSCordlike organ that is part of the PNS– Consists of parallel bundles of peripheral axons enclosed by Consists of parallel bundles of peripheral axons enclosed by
connective tissue wrappingsconnective tissue wrappings
GangliaGanglia– Collections of neuron cell bodies associated with nerves in the PNSCollections of neuron cell bodies associated with nerves in the PNS
Efferent motor endingsEfferent motor endings
Peripheral Nervous System
12 cranial nerves– Associated with the brain– We need to learn their:
Names Locations Functions
31 spinal nerves– Associated with the spinal cord– We need to learn their:
Plexus Functions
Cranial NervesCranial Nerves
10 of 12 cranial nerves attach to the brain stem 10 of 12 cranial nerves attach to the brain stem Their name reflects their function or the major Their name reflects their function or the major
structures they controlstructures they control Numbered (Roman numerals) in order from Numbered (Roman numerals) in order from
anterior to posterioranterior to posterior Described by name, Roman numeral, and functionDescribed by name, Roman numeral, and function Function can be purely sensory, motor, or bothFunction can be purely sensory, motor, or both
Cranial NervesCranial Nerves I Olfactory nerve (sensory)
smell
II Optic nerve (sensory)
vision
III Oculomotor nerve (motor)
eye muscles
IV Trochlear (motor)
eye muscles
V Trigeminal nerve (sensory/motor)
sensory for face
motor for chewing
VI Abducens nerve (motor)
eye muscles
Cranial NervesCranial Nerves VII Facial nerve (sensory/motor)
sensory for taste
Motor for facial expression
VIII Vestibulococchlear nerve (sensory)
balance and hearing
IX Glossopharyngeal nerve (sensory/motor)
sensory for taste
motor for pharynx
X Vagus nerves (sensory/motor)
pharynx, larynx, and viscera
XI Accessory nerve (motor)
neck and upper back
XII Hypoglossal nerve (motor)
tongue
Here are mnemonic devices for the 12 cranial nerves:– On occasion our trusty truck
acts funny – very good vehicle anyhow
– On old Olympus' towering tops, a fin and German viewed some hops.
– Olfactory, optic, oculomotor, trochlear, trigeminal, abducens, facial, vestibulococchlear, glossopharyngeal, vagus, hypoglossal
Cranial NervesCranial Nerves
Cranial nerves can have sensory only, motor only, or mixed functions
Sensory only– Olfactory and optic are sensory only
Motor only– Oculomotor– Trochlear– Abducens– Accessory– Hypoglossal
Mixed (sensory and motor)– Trigeminal– Facial– Vestibulococchlear– Glossopharyngeal– Vagus
Mnemonic device to help: – Some say marry money but my brother says
big butts matter more.– Some Scientists Make Money But My Brother Some Scientists Make Money But My Brother
Says Beautiful Blonds Make More Says Beautiful Blonds Make More
Cranial NervesCranial Nerves
Olfactory (I)Sensory
SmellImbalance: fracture of ethmoid bone or lesions
may result in partial or total loss of smell
Optic (II)SensoryVision
Imbalance: damage to optic nerve results in blindness in eye served by nerve; damage beyond optic chiasm
results in partial vision loss
Oculomotor (III)Motor
Eye and pupil movementImbalance: eye cannot move up, down or inward; at rest
eye rotates laterally and trouble focusing on close objects
Trochlear (IV)Motor
Eye and peripheral visionImbalance: Trauma or paralysis results in double vision
and reduced ability to rotate eye inferolaterally
Trigeminal (V)Both (sensory and motor)
Ophthalmic division (s)Maxillary division (s)
Mandibular division (s & m)Largest of the cranial nerves
Imbalance: trigeminal neuralgia – caused by inflammation of the nerve, stabbing pain that lasts for a few seconds to a
minute, provoked by a sensory stimulus
Abducens (VI)Motor
Abduction of eyeImbalance: eye cannot be moved laterally; at rest, affected
eyeball rotates medially
Facial Nerves (VII)Both (sensory and motor)
Muscles of facial expression: temporal, zygomatic, buccal, mandibular, cervical (m)
Taste buds (anterior) (s)Imbalance: Bell’s Palsy – paralysis of facial muscles on
affected side and partial loss of taste sensation; Lower eyelid droops, corner of mouth sags, tears drip continuously from eye
and eye cannot be completely closed
Vestibulocochlear (VIII)
SensoryHearing (cochlear)
Equilibrium (vestibular)Imbalance: lesions of cochlear nerve result in nerve deafness; damage to vestibular produces dizziness, rapid involuntary eye
movement, loss of balance, nausea and vomiting
Glossopharyngeal (IX)Both (sensory and motor)
Pharynx (throat)(m)Taste buds and throat (posterior) (s)
Imbalance: injury impairs swallowing and taste
Vagus (X)Only cranial nerve to extend beyond
head and neckBoth (sensory and motor)
Pharynx, larynx, heart, lungs, and abdominal organs (m)
Thoracic and abdominal organs (s)Imbalance: Injury can lead to hoarseness or loss of voice, difficulty swallowing and impaired digestive
system motilityTotal destruction of nerves is incompatible with life
because they are needed to maintain normal activity
Accessory (XI)Motor
Trapezius and sternocleidomastoid
Hypoglossal (XII)Motor
Glossal = tongueMuscles of the tongue
Imbalance: difficulty in speech and swallowing
Spinal nerves are named for the region from which they arise
A pair of spinal nerves at each vertebrae for a total of 31 pairs– 8 pairs of cervical
(1 extra)
– 12 pairs of thoracic
– 5 pairs of lumbar
– 5 pairs of sacral
– 1 pair of coccyx
Spinal NervesSpinal Nerves
All are mixed nerves (sensory and motor) Each nerve connects to the spinal cord by a dorsal and ventral root
– Ventral root – motor
– Dorsal root – sensory
Spinal NervesSpinal Nerves
The spinal nerve is actually short (1-2 cm)
Immediately it divides into its ramus (branch)– Dorsal rami – serve the skin and
muscles of the posterior trunk
– Ventral rami – forms a complex of networks for the anterior and limbs called plexuses
Spinal NervesSpinal Nerves
PlexusesPlexuses All ventral rami (except
thoracic) branch and join one another lateral to the vertebral column that form a complex network called a plexus
Nerve plexuses occur in cervical, brachial, lumbar and sacral regions to serve the motor and sensory needs of the limbs
The fibers diverge again from the plexuses to form the peripheral nerves
Examples of Nerve DistributionExamples of Nerve Distribution
Figure 7.23
Spinal Nerve PlexusesSpinal Nerve PlexusesPLEXUSPLEXUS SPINAL ROOTS SPINAL ROOTS
(ORIGIN)(ORIGIN)BODY AREA SERVEDBODY AREA SERVED IMBALANCEIMBALANCE
CervicalCervical CC11-C-C55 Skin of neck, shoulder Skin of neck, shoulder and clavicle regionand clavicle region
Diaphragm (phrenic Diaphragm (phrenic nerve) and muscles of nerve) and muscles of shoulder and neckshoulder and neck
Irritation of the phrenic Irritation of the phrenic nerve causes spasms of nerve causes spasms of the diaphragm - hiccupsthe diaphragm - hiccups
BrachialBrachial CC55– C– C88 and T and T11 All nerves that innervate All nerves that innervate upper limbupper limb
Arm muscles – deltoid, Arm muscles – deltoid, triceps, biceps, flexor, triceps, biceps, flexor, extensor, wrist and handsextensor, wrist and hands
Cutaneous sensation of Cutaneous sensation of the upper limbthe upper limb
Weakness or paralysis of Weakness or paralysis of entire upper limbentire upper limb
Carpal tunnel syndrome Carpal tunnel syndrome the median nerve is the median nerve is compressedcompressed
““The funny bone” results The funny bone” results from an injury to the from an injury to the ulnar nerveulnar nerve
Spinal Nerve PlexusesSpinal Nerve Plexuses
PLEXUSPLEXUS SPINAL SPINAL ROOTS ROOTS (ORIGIN)(ORIGIN)
BODY AREA SERVEDBODY AREA SERVED IMBALANCEIMBALANCE
LumbarLumbar LL11– L– L44 Innervation of lower limb and Innervation of lower limb and abdomenabdomen
Muscles of the thigh, leg and footMuscles of the thigh, leg and foot
Cutaneous sensation of thigh, leg, Cutaneous sensation of thigh, leg, foot, external genitalia and lower foot, external genitalia and lower abdomenabdomen
Compression of the Compression of the spinal roots of the spinal roots of the lumbar plexus results lumbar plexus results in walking problemsin walking problems
SacralSacral LL44 – S – S44 Innervation of the buttock, pelvic Innervation of the buttock, pelvic structures and lower limbstructures and lower limb
Sciatic nerve is the thickest and Sciatic nerve is the thickest and longest nerve in the body –entire longest nerve in the body –entire lower limblower limb
Muscles of the posterior surface of Muscles of the posterior surface of buttock, thigh, leg and foot,buttock, thigh, leg and foot,
Cutaneous sensation of posterior Cutaneous sensation of posterior surface of buttock, thigh, leg and foot, surface of buttock, thigh, leg and foot,
Sciatica – stabbing Sciatica – stabbing pain over the course pain over the course of the nerve from of the nerve from injury to sciatic nerve injury to sciatic nerve such as disc such as disc herniation or herniation or improper injection in improper injection in the buttockthe buttock
ReflexesReflexes
The ReflexThe Reflex Anyone who has had a routine physical examination
is familiar with the reflex tests done to assess neural function.
A tap with a reflex hammer stretches your quadriceps tendon and your anterior thigh muscles contract, which results in the knee-jerk response
This response shows that the spinal cord and upper brain centers are functioning normally
Abnormal reflex test responses may indicate such serious disorders as intracranial hemorrhage, multiple sclerosis, or hydrocephalus
Reflex ArcReflex Arc Reflex
– Rapid, predictable, involuntary motor response to stimuli– Inborn or acquired reflexes– Occur over neural pathways called reflex arcs
Reflex arc – Receptor sensory neuron integration center
(monosynaptic or polysynaptic) motor neuron effector
ReflexesReflexes Receptor
– Site of the stimulus
Sensory neuron – Transmits afferent impulses to the CNS
Integration center – Single synapse (monosynaptic)– Multiple synapses (polysynaptic) btw the afferent
Motor neuron – Conducts efferent impulses from the integration center to an
effector organ
Effector– Muscle fiber or gland cell that responds to the impulses
Reflex ArcsReflex Arcs Monosynaptic reflex arc – knee-jerk reflex Polysynaptic reflex arc – most reflexes
Types of ReflexesTypes of Reflexes
Somatic reflexes– Any reflex in which the skeletal muscles are the effectors– Stretch reflexes
Maintain posture, balance and locomotion Produced by tapping a tendon, which stretches the attached
muscle Knee-jerk (patellar) reflex
– Superficial reflexes Gentle cutaneous stimulation Plantar reflex tests the integrity of lower spinal cord Corneal reflex Gag reflex
Autonomic reflexes– Smooth muscle
regulation– Heart and blood
pressure regulation– Digestive system
regulation (saliva)– Elimination (excretion)– Change size of eye pupil – Sweating
Types of ReflexesTypes of Reflexes
Types of ReflexesTypes of Reflexes