Patient: Carla PennypackerPatient: Carla Pennypacker

Diagnosis: Chrons DiseaseDiagnosis: Chrons Disease

Chrons DiseaseChrons Disease

Symptoms of ChronsSymptoms of ChronsSymptoms: Carla has experienced Symptoms: Carla has experienced Abdominal pains Abdominal pains Abdominal pains Abdominal pains Diarrhea Diarrhea Diarrhea Diarrhea Weight loss Weight lossWeight loss Weight lossPoor appetite Poor appetite Fever Fever Night sweatsNight sweatsRectal pains Cramps in abdomen and sidesRectal pains Cramps in abdomen and sidesSevere inflammation Severe inflammation Inflammation in the colonInflammation in the colonBloody Diarrhea DiarrheaBloody Diarrhea DiarrheaAnal fistulaeAnal fistulaePeri-Rectal abscessesPeri-Rectal abscessesInflammation in small intestineInflammation in small intestineTiredness Sluggish/ Tired Tiredness Sluggish/ Tired

Body Systems AffectedBody Systems Affected

Digestive System: Digestive System: The The small intestine is inflamed small intestine is inflamed therefore affecting the digestive therefore affecting the digestive systemsystem

Excretory System: Excretory System: The The Large intestine is inflamed Large intestine is inflamed therefore affecting the Excretory therefore affecting the Excretory systemsystem

Circulatory System: Circulatory System: The The blood iron level lowers because of blood iron level lowers because of Chrons which can result in Anemia Chrons which can result in Anemia which affects the Circulatory which affects the Circulatory

systemsystem

TestsTests

Tests requested: Test results:Tests requested: Test results:CBC CBC: RBC – 4.0 CBC CBC: RBC – 4.0

Colonoscopy WBC: 15,000 Shows severeColonoscopy WBC: 15,000 Shows severe

inflammation in colon inflammation in colon

Blood Iron Level Hematocrit: 30%Blood Iron Level Hematocrit: 30%

Upper GI Series Shows narrowing and Upper GI Series Shows narrowing and

inflammation inflammation

TreatmentTreatment

Treatments: Treatments: Patients Patients with rare or mild with rare or mild symptoms don’t need any symptoms don’t need any medications at all. There is medications at all. There is no cure for Chrons but no cure for Chrons but remissions help heal the remissions help heal the swollen and infected swollen and infected systems.systems.

Our suggestionOur suggestionWe think that the best We think that the best

option for your option for your treatment is to take treatment is to take Infliximab which is a Infliximab which is a new generation of new generation of medicine that controls medicine that controls the TNF (Tumor the TNF (Tumor Necrosis Factor) which Necrosis Factor) which is a chemical in the is a chemical in the body that causes body that causes inflammation so the inflammation so the inflammation is inflammation is controlled.controlled.

InfliximabInfliximab

Side Affect: Side Affect: Allergic reactions like skin rash, itching or hives, swelling of Allergic reactions like skin rash, itching or hives, swelling of

the face, lips, or tonguethe face, lips, or tongueChest painChest painFever or chills, usually related to the infusionFever or chills, usually related to the infusionMuscle or joint painMuscle or joint painRed, scaly patches or raised bumps on the skinRed, scaly patches or raised bumps on the skin

Signs of infection - fever or chills, cough, sore throat, pain Signs of infection - fever or chills, cough, sore throat, pain or difficulty passing urineor difficulty passing urineSwollen lymph nodes in the neck, underarm, or groin areasSwollen lymph nodes in the neck, underarm, or groin areasUnexplained weight lossUnexplained weight lossUnusual bleeding or bruisingUnusual bleeding or bruisingUnusually weak or tiredUnusually weak or tiredYellowing of the eyes or skinYellowing of the eyes or skin

You should report to your doctor as soon as possible if you You should report to your doctor as soon as possible if you experience any of these side effects. experience any of these side effects.

You should tell your doctor if you You should tell your doctor if you have any of the followinghave any of the following

Tuberculosis (TB) or have been near someone who has TB. Your Tuberculosis (TB) or have been near someone who has TB. Your doctor will check you for TB with a skin test. If you have latent doctor will check you for TB with a skin test. If you have latent (inactive) TB, you will begin TB treatment before you start (inactive) TB, you will begin TB treatment before you start REMICADE®.REMICADE®.

Lived in a region where certain fungal infections like histoplasmosis Lived in a region where certain fungal infections like histoplasmosis or coccidioidomycosis are common.or coccidioidomycosis are common.

Infections that keep coming back, have diabetes or an immune Infections that keep coming back, have diabetes or an immune system problem.system problem.

Any type of cancer or a risk factor for developing cancer, for Any type of cancer or a risk factor for developing cancer, for example, chronic obstructive pulmonary disease (COPD) or had example, chronic obstructive pulmonary disease (COPD) or had phototherapy for psoriasis.phototherapy for psoriasis.

Heart failure or any heart condition. Many people with heart failure Heart failure or any heart condition. Many people with heart failure should not take REMICADE®.should not take REMICADE®.

Hepatitis B virus (HBV) infection or think you may be a carrier of HBV.Hepatitis B virus (HBV) infection or think you may be a carrier of HBV.Nervous system disorders (like multiple sclerosis or Guillain-Barré Nervous system disorders (like multiple sclerosis or Guillain-Barré

syndrome).syndrome).

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