Partnering with Federal LabsPartnering with Federal LabsA Panel DiscussionA Panel Discussion

FLC Mid-Atlantic Region Annual Meeting

October 24 2007

Traversing the MazeTraversing the Maze

Panel MembersPanel Members Department of CommerceDepartment of Commerce

George Arnold PhD National Institute of Standards and TechnologyGeorge Arnold PhD National Institute of Standards and Technology Department of Agricultural Department of Agricultural

Rick Brenner PhD Agricultural Resource ServicesRick Brenner PhD Agricultural Resource Services Department of DefenseDepartment of Defense

Paul Mele Army Medical Research and Materiel Command Paul Mele Army Medical Research and Materiel Command National Aeronautics and Space AdministrationNational Aeronautics and Space Administration

Ray Turcotte PhD Langley Research Center Ray Turcotte PhD Langley Research Center Department of Health and Human ServicesDepartment of Health and Human Services

Tom Stackhouse PhD National Cancer Institute NIHTom Stackhouse PhD National Cancer Institute NIH

Collaborative R amp D with the Collaborative R amp D with the National Institutes of HealthNational Institutes of Health

Tom Stackhouse PhDTom Stackhouse PhD

Assistant DirectorAssistant Director

Technology Transfer CenterTechnology Transfer Center

National Cancer InstituteNational Cancer Institute

National Institutes of HealthNational Institutes of Health

FLC Mid-Atlantic Region Annual Meeting October 24 2007

National Institutes of HealthNational Institutes of HealthThe National Institutes of Health (NIH) an agency of theThe National Institutes of Health (NIH) an agency of the

US Department of Health and Human Services is theUS Department of Health and Human Services is theprimary US Federal agency for conducting andprimary US Federal agency for conducting and

supporting medical researchsupporting medical research

27 Institutes amp Centers at NIH27 Institutes amp Centers at NIH

NIHFDA Intramural Portfolios(2006)

1048708 383 invention disclosures (168 from NCI)1048708 101 US patents issued (50 from NCI)1048708 3400+ total pendingissued patents1048708 254 licenses executed (122 from NCI)1048708 364 technologies (inventions) were

licensed (167 from NCI)1048708 1300+ active licenses1048708 $827 million in royalties collected

1048708 51 CRADAs executed (NIH only)1048708 222 active CRADAs (NIH only)

Interactive OfficesInteractive Offices

bull Patent Prosecution via 14 contract patent law firmsPatent Prosecution via 14 contract patent law firmsbull LicensesLicenses

bull Transactional Agreementsbull Collaborative Research Agreementsbull Specialized Agreements

The Institute Technology TransferDevelopment Offices

The NIH Office of Technology Transfer

LicensesLicenses

Commercial Evaluation LicensesCommercial Evaluation Licenses Internal Commercial Use LicensesInternal Commercial Use Licenses Nonexclusive Patent Licenses Nonexclusive Patent Licenses Exclusive Patent LicensesExclusive Patent Licenses Biological Materials LicensesBiological Materials Licenses NIH Technologies available for licensing NIH Technologies available for licensing

httpottodnihgovdbtechasp

Licensing is centralized NIH Office of Technology Transfer (OTT)

Traversing the MazeTraversing the Maze

Panel MembersPanel Members Department of CommerceDepartment of Commerce

George Arnold PhD National Institute of Standards and TechnologyGeorge Arnold PhD National Institute of Standards and Technology Department of Agricultural Department of Agricultural

Rick Brenner PhD Agricultural Resource ServicesRick Brenner PhD Agricultural Resource Services Department of DefenseDepartment of Defense

Paul Mele Army Medical Research and Materiel Command Paul Mele Army Medical Research and Materiel Command National Aeronautics and Space AdministrationNational Aeronautics and Space Administration

Ray Turcotte PhD Langley Research Center Ray Turcotte PhD Langley Research Center Department of Health and Human ServicesDepartment of Health and Human Services

Tom Stackhouse PhD National Cancer Institute NIHTom Stackhouse PhD National Cancer Institute NIH

Collaborative R amp D with the Collaborative R amp D with the National Institutes of HealthNational Institutes of Health

Tom Stackhouse PhDTom Stackhouse PhD

Assistant DirectorAssistant Director

Technology Transfer CenterTechnology Transfer Center

National Cancer InstituteNational Cancer Institute

National Institutes of HealthNational Institutes of Health

FLC Mid-Atlantic Region Annual Meeting October 24 2007

National Institutes of HealthNational Institutes of HealthThe National Institutes of Health (NIH) an agency of theThe National Institutes of Health (NIH) an agency of the

US Department of Health and Human Services is theUS Department of Health and Human Services is theprimary US Federal agency for conducting andprimary US Federal agency for conducting and

supporting medical researchsupporting medical research

27 Institutes amp Centers at NIH27 Institutes amp Centers at NIH

NIHFDA Intramural Portfolios(2006)

1048708 383 invention disclosures (168 from NCI)1048708 101 US patents issued (50 from NCI)1048708 3400+ total pendingissued patents1048708 254 licenses executed (122 from NCI)1048708 364 technologies (inventions) were

licensed (167 from NCI)1048708 1300+ active licenses1048708 $827 million in royalties collected

1048708 51 CRADAs executed (NIH only)1048708 222 active CRADAs (NIH only)

Interactive OfficesInteractive Offices

bull Patent Prosecution via 14 contract patent law firmsPatent Prosecution via 14 contract patent law firmsbull LicensesLicenses

bull Transactional Agreementsbull Collaborative Research Agreementsbull Specialized Agreements

The Institute Technology TransferDevelopment Offices

The NIH Office of Technology Transfer

LicensesLicenses

Commercial Evaluation LicensesCommercial Evaluation Licenses Internal Commercial Use LicensesInternal Commercial Use Licenses Nonexclusive Patent Licenses Nonexclusive Patent Licenses Exclusive Patent LicensesExclusive Patent Licenses Biological Materials LicensesBiological Materials Licenses NIH Technologies available for licensing NIH Technologies available for licensing

httpottodnihgovdbtechasp

Licensing is centralized NIH Office of Technology Transfer (OTT)

Panel MembersPanel Members Department of CommerceDepartment of Commerce

George Arnold PhD National Institute of Standards and TechnologyGeorge Arnold PhD National Institute of Standards and Technology Department of Agricultural Department of Agricultural

Rick Brenner PhD Agricultural Resource ServicesRick Brenner PhD Agricultural Resource Services Department of DefenseDepartment of Defense

Paul Mele Army Medical Research and Materiel Command Paul Mele Army Medical Research and Materiel Command National Aeronautics and Space AdministrationNational Aeronautics and Space Administration

Ray Turcotte PhD Langley Research Center Ray Turcotte PhD Langley Research Center Department of Health and Human ServicesDepartment of Health and Human Services

Tom Stackhouse PhD National Cancer Institute NIHTom Stackhouse PhD National Cancer Institute NIH

Collaborative R amp D with the Collaborative R amp D with the National Institutes of HealthNational Institutes of Health

Tom Stackhouse PhDTom Stackhouse PhD

Assistant DirectorAssistant Director

Technology Transfer CenterTechnology Transfer Center

National Cancer InstituteNational Cancer Institute

National Institutes of HealthNational Institutes of Health

FLC Mid-Atlantic Region Annual Meeting October 24 2007

National Institutes of HealthNational Institutes of HealthThe National Institutes of Health (NIH) an agency of theThe National Institutes of Health (NIH) an agency of the

US Department of Health and Human Services is theUS Department of Health and Human Services is theprimary US Federal agency for conducting andprimary US Federal agency for conducting and

supporting medical researchsupporting medical research

27 Institutes amp Centers at NIH27 Institutes amp Centers at NIH

NIHFDA Intramural Portfolios(2006)

1048708 383 invention disclosures (168 from NCI)1048708 101 US patents issued (50 from NCI)1048708 3400+ total pendingissued patents1048708 254 licenses executed (122 from NCI)1048708 364 technologies (inventions) were

licensed (167 from NCI)1048708 1300+ active licenses1048708 $827 million in royalties collected

1048708 51 CRADAs executed (NIH only)1048708 222 active CRADAs (NIH only)

Interactive OfficesInteractive Offices

bull Patent Prosecution via 14 contract patent law firmsPatent Prosecution via 14 contract patent law firmsbull LicensesLicenses

bull Transactional Agreementsbull Collaborative Research Agreementsbull Specialized Agreements

The Institute Technology TransferDevelopment Offices

The NIH Office of Technology Transfer

LicensesLicenses

Commercial Evaluation LicensesCommercial Evaluation Licenses Internal Commercial Use LicensesInternal Commercial Use Licenses Nonexclusive Patent Licenses Nonexclusive Patent Licenses Exclusive Patent LicensesExclusive Patent Licenses Biological Materials LicensesBiological Materials Licenses NIH Technologies available for licensing NIH Technologies available for licensing

httpottodnihgovdbtechasp

Licensing is centralized NIH Office of Technology Transfer (OTT)

Collaborative R amp D with the Collaborative R amp D with the National Institutes of HealthNational Institutes of Health

Tom Stackhouse PhDTom Stackhouse PhD

Assistant DirectorAssistant Director

Technology Transfer CenterTechnology Transfer Center

National Cancer InstituteNational Cancer Institute

National Institutes of HealthNational Institutes of Health

FLC Mid-Atlantic Region Annual Meeting October 24 2007

National Institutes of HealthNational Institutes of HealthThe National Institutes of Health (NIH) an agency of theThe National Institutes of Health (NIH) an agency of the

US Department of Health and Human Services is theUS Department of Health and Human Services is theprimary US Federal agency for conducting andprimary US Federal agency for conducting and

supporting medical researchsupporting medical research

27 Institutes amp Centers at NIH27 Institutes amp Centers at NIH

NIHFDA Intramural Portfolios(2006)

1048708 383 invention disclosures (168 from NCI)1048708 101 US patents issued (50 from NCI)1048708 3400+ total pendingissued patents1048708 254 licenses executed (122 from NCI)1048708 364 technologies (inventions) were

licensed (167 from NCI)1048708 1300+ active licenses1048708 $827 million in royalties collected

1048708 51 CRADAs executed (NIH only)1048708 222 active CRADAs (NIH only)

Interactive OfficesInteractive Offices

bull Patent Prosecution via 14 contract patent law firmsPatent Prosecution via 14 contract patent law firmsbull LicensesLicenses

bull Transactional Agreementsbull Collaborative Research Agreementsbull Specialized Agreements

The Institute Technology TransferDevelopment Offices

The NIH Office of Technology Transfer

LicensesLicenses

Commercial Evaluation LicensesCommercial Evaluation Licenses Internal Commercial Use LicensesInternal Commercial Use Licenses Nonexclusive Patent Licenses Nonexclusive Patent Licenses Exclusive Patent LicensesExclusive Patent Licenses Biological Materials LicensesBiological Materials Licenses NIH Technologies available for licensing NIH Technologies available for licensing

httpottodnihgovdbtechasp

Licensing is centralized NIH Office of Technology Transfer (OTT)

National Institutes of HealthNational Institutes of HealthThe National Institutes of Health (NIH) an agency of theThe National Institutes of Health (NIH) an agency of the

US Department of Health and Human Services is theUS Department of Health and Human Services is theprimary US Federal agency for conducting andprimary US Federal agency for conducting and

supporting medical researchsupporting medical research

27 Institutes amp Centers at NIH27 Institutes amp Centers at NIH

NIHFDA Intramural Portfolios(2006)

1048708 383 invention disclosures (168 from NCI)1048708 101 US patents issued (50 from NCI)1048708 3400+ total pendingissued patents1048708 254 licenses executed (122 from NCI)1048708 364 technologies (inventions) were

licensed (167 from NCI)1048708 1300+ active licenses1048708 $827 million in royalties collected

1048708 51 CRADAs executed (NIH only)1048708 222 active CRADAs (NIH only)

Interactive OfficesInteractive Offices

bull Patent Prosecution via 14 contract patent law firmsPatent Prosecution via 14 contract patent law firmsbull LicensesLicenses

bull Transactional Agreementsbull Collaborative Research Agreementsbull Specialized Agreements

The Institute Technology TransferDevelopment Offices

The NIH Office of Technology Transfer

LicensesLicenses

Commercial Evaluation LicensesCommercial Evaluation Licenses Internal Commercial Use LicensesInternal Commercial Use Licenses Nonexclusive Patent Licenses Nonexclusive Patent Licenses Exclusive Patent LicensesExclusive Patent Licenses Biological Materials LicensesBiological Materials Licenses NIH Technologies available for licensing NIH Technologies available for licensing

httpottodnihgovdbtechasp

Licensing is centralized NIH Office of Technology Transfer (OTT)

27 Institutes amp Centers at NIH27 Institutes amp Centers at NIH

NIHFDA Intramural Portfolios(2006)

1048708 383 invention disclosures (168 from NCI)1048708 101 US patents issued (50 from NCI)1048708 3400+ total pendingissued patents1048708 254 licenses executed (122 from NCI)1048708 364 technologies (inventions) were

licensed (167 from NCI)1048708 1300+ active licenses1048708 $827 million in royalties collected

1048708 51 CRADAs executed (NIH only)1048708 222 active CRADAs (NIH only)

Interactive OfficesInteractive Offices

bull Patent Prosecution via 14 contract patent law firmsPatent Prosecution via 14 contract patent law firmsbull LicensesLicenses

bull Transactional Agreementsbull Collaborative Research Agreementsbull Specialized Agreements

The Institute Technology TransferDevelopment Offices

The NIH Office of Technology Transfer

LicensesLicenses

Commercial Evaluation LicensesCommercial Evaluation Licenses Internal Commercial Use LicensesInternal Commercial Use Licenses Nonexclusive Patent Licenses Nonexclusive Patent Licenses Exclusive Patent LicensesExclusive Patent Licenses Biological Materials LicensesBiological Materials Licenses NIH Technologies available for licensing NIH Technologies available for licensing

httpottodnihgovdbtechasp

Licensing is centralized NIH Office of Technology Transfer (OTT)

NIHFDA Intramural Portfolios(2006)

1048708 383 invention disclosures (168 from NCI)1048708 101 US patents issued (50 from NCI)1048708 3400+ total pendingissued patents1048708 254 licenses executed (122 from NCI)1048708 364 technologies (inventions) were

licensed (167 from NCI)1048708 1300+ active licenses1048708 $827 million in royalties collected

1048708 51 CRADAs executed (NIH only)1048708 222 active CRADAs (NIH only)

Interactive OfficesInteractive Offices

bull Patent Prosecution via 14 contract patent law firmsPatent Prosecution via 14 contract patent law firmsbull LicensesLicenses

bull Transactional Agreementsbull Collaborative Research Agreementsbull Specialized Agreements

The Institute Technology TransferDevelopment Offices

The NIH Office of Technology Transfer

LicensesLicenses

Commercial Evaluation LicensesCommercial Evaluation Licenses Internal Commercial Use LicensesInternal Commercial Use Licenses Nonexclusive Patent Licenses Nonexclusive Patent Licenses Exclusive Patent LicensesExclusive Patent Licenses Biological Materials LicensesBiological Materials Licenses NIH Technologies available for licensing NIH Technologies available for licensing

httpottodnihgovdbtechasp

Licensing is centralized NIH Office of Technology Transfer (OTT)

Interactive OfficesInteractive Offices

bull Patent Prosecution via 14 contract patent law firmsPatent Prosecution via 14 contract patent law firmsbull LicensesLicenses

bull Transactional Agreementsbull Collaborative Research Agreementsbull Specialized Agreements

The Institute Technology TransferDevelopment Offices

The NIH Office of Technology Transfer

LicensesLicenses

Commercial Evaluation LicensesCommercial Evaluation Licenses Internal Commercial Use LicensesInternal Commercial Use Licenses Nonexclusive Patent Licenses Nonexclusive Patent Licenses Exclusive Patent LicensesExclusive Patent Licenses Biological Materials LicensesBiological Materials Licenses NIH Technologies available for licensing NIH Technologies available for licensing

httpottodnihgovdbtechasp

Licensing is centralized NIH Office of Technology Transfer (OTT)

LicensesLicenses

Commercial Evaluation LicensesCommercial Evaluation Licenses Internal Commercial Use LicensesInternal Commercial Use Licenses Nonexclusive Patent Licenses Nonexclusive Patent Licenses Exclusive Patent LicensesExclusive Patent Licenses Biological Materials LicensesBiological Materials Licenses NIH Technologies available for licensing NIH Technologies available for licensing

httpottodnihgovdbtechasp

Licensing is centralized NIH Office of Technology Transfer (OTT)

Resources to Collaborate with NCIResources to Collaborate with NCI

Unique research and clinical grade Unique research and clinical grade materialsmaterials Unique Unique expertiseexpertise for mutual projects for mutual projects Unique Unique testingtesting capabilities capabilities Extensive Extensive clinical trials networkclinical trials network for cancer for cancer Specific projects to develop Specific projects to develop NCIrsquos patented NCIrsquos patented

technologiestechnologies

httpttcncinihgov

Mechanisms for CollaborationMechanisms for Collaboration Material Transfer AgreementsMaterial Transfer Agreements Confidential Disclosure AgreementConfidential Disclosure Agreement Cooperative Research And Development Agreement Cooperative Research And Development Agreement

(CRADA)(CRADA) Clinical Trials CRADAClinical Trials CRADA Collaboration AgreementCollaboration Agreement Clinical Trial AgreementsClinical Trial Agreements Beta Testing AgreementBeta Testing Agreement Screening AgreementScreening Agreement OthersOthers

httpttcncinihgov

Collaborative OpportunitiesCollaborative Opportunities

The following links provide more information about identified areas whereThe following links provide more information about identified areas wherethe NCI is seeking the NCI is seeking collaboratorscollaborators to enter into research to enter into researchpartnershipspartnerships

Software (3)Software (3) Therapeutics (35)Therapeutics (35) Vaccines (1)Vaccines (1) Devices (9)Devices (9) Diagnostics (13)Diagnostics (13) Research Reagents (6)Research Reagents (6) Other Technologies (5)Other Technologies (5)

NOTE These are just for NCI one of the 27NOTE These are just for NCI one of the 27

httpttcncinihgov

Collaborative OpportunitiesCollaborative Opportunities

The following links provide more information about identified areas whereThe following links provide more information about identified areas wherethe NCI is seeking the NCI is seeking collaboratorscollaborators to enter into research to enter into researchpartnershipspartnerships

Software (3)Software (3) Therapeutics (35)Therapeutics (35) Vaccines (1)Vaccines (1) Devices (9)Devices (9) Diagnostics (13)Diagnostics (13) Research Reagents (6)Research Reagents (6) Other Technologies (5)Other Technologies (5)

NOTE These are just for NCI one of the 27NOTE These are just for NCI one of the 27

Resource Examples from NCIResource Examples from NCI

Discovery and Developmental ProgramsDiscovery and Developmental Programs

Clinical Trials ProgramClinical Trials Program

NCI-Frederick a Federally Funded Research and NCI-Frederick a Federally Funded Research and Development Center (FFRDC)Development Center (FFRDC)

Alliance for Nanotechnology in CancerAlliance for Nanotechnology in Cancer

Identifying the Unique NIH Identifying the Unique NIH Programs to fit your needsPrograms to fit your needs

What are the appropriate NIH programs What are the appropriate NIH programs Disease(s) and ApplicationsDisease(s) and Applications

prevention diagnosis treatmentprevention diagnosis treatment Stage of DevelopmentStage of Development Type of agent Type of agent

small molecule biologicsmall molecule biologic Eligible organizations Eligible organizations

academicgovernment industryacademicgovernment industry

NCI Developmental Therapeutic Program (DTP) NCI Developmental Therapeutic Program (DTP) provides resources forprovides resources for

DiscoveryDiscovery Compounds (repositories)Compounds (repositories) informatics (public database)informatics (public database) cell linescell lines screening servicesscreening services Natural Products Natural Products

Development Development formulation formulation In vivoIn vivo testing testing PharmacologyPharmacology toxicologytoxicology

Rapid Access to Intervention Development (RAID)Rapid Access to Intervention Development (RAID)Clinical proof of principleldquo that a new molecule or approach is a viable candidate for expanded clinical evaluation

Provides NCI Provides NCI resourcesresources including our contract resources including our contract resources- Small- medium scale production- Small- medium scale production- Bulk supply- Bulk supply- GMP manufacturing- GMP manufacturing- formulation- formulation- Toxicology- Toxicology

httpdtpncinihgovdocsraidhttpdtpncinihgovdocsraid

Pre-Clinical through ClinicalPre-Clinical through Clinical

NCI Drug Development GroupNCI Drug Development Group

Cancer Therapy Evaluation Program (CTEP)Cancer Therapy Evaluation Program (CTEP)

Pre-clinical development and clinical development of Pre-clinical development and clinical development of cancer therapeuticscancer therapeutics

National Network of Clinical CentersNational Network of Clinical Centers httpctepcancergovhttpctepcancergov

NCI-FrederickNCI-Frederick

Federal Funded Research and Development Federal Funded Research and Development CenterCenter

Government-Owned Contactor-operated Government-Owned Contactor-operated facilityfacility

Contractor is currently SAIC-Frederick IncContractor is currently SAIC-Frederick Inc

Services and SupportServices and SupportNCI-FrederickNCI-Frederick

biopharmaceutical development program biopharmaceutical development program a high-performance IT center dedicated to biomedical a high-performance IT center dedicated to biomedical

research and informaticsresearch and informatics advanced technology programsadvanced technology programs

genomics genomics proteomics proteomics imaging imaging nanotechnology nanotechnology histopathologyhistopathology molecular biology molecular biology

clinical trial laboratory servicesclinical trial laboratory services

NCI Nanotechnology Characterization NCI Nanotechnology Characterization Laboratory (NCL)Laboratory (NCL)

Characterization of physical attributes pre-clinical Characterization of physical attributes pre-clinical toxicology and efficacy testing of nanoparticles intended toxicology and efficacy testing of nanoparticles intended for cancer therapy imaging and diagnosticsfor cancer therapy imaging and diagnostics

Partners with NIST and the FDAPartners with NIST and the FDA

httpnclcancergovworking_application-processasphttpnclcancergovworking_application-processasp

Check Handout and links for more Check Handout and links for more informationinformation

Description of programDescription of program Eligibility requirementsEligibility requirements Types of servicesTypes of services Application proceduresApplication procedures Intellectual property considerationsIntellectual property considerations Funded projects and outcomesFunded projects and outcomes

QuestionsQuestions

Thomas M Stackhouse PhDThomas M Stackhouse PhD

Assistant DirectorAssistant Director

Technology Transfer CenterTechnology Transfer Center

National Cancer InstituteNational Cancer Institute

stackhotmailnihgovstackhotmailnihgov

NIH Technology Development CoordinatorsNIH Technology Development Coordinators

httpottodnihgovnih_stafftdchtmlhttpottodnihgovnih_stafftdchtml

Identifying the Unique NIH Identifying the Unique NIH Programs to fit your needsPrograms to fit your needs

What are the appropriate NIH programs What are the appropriate NIH programs Disease(s) and ApplicationsDisease(s) and Applications

prevention diagnosis treatmentprevention diagnosis treatment Stage of DevelopmentStage of Development Type of agent Type of agent

small molecule biologicsmall molecule biologic Eligible organizations Eligible organizations

academicgovernment industryacademicgovernment industry

NCI Developmental Therapeutic Program (DTP) NCI Developmental Therapeutic Program (DTP) provides resources forprovides resources for

DiscoveryDiscovery Compounds (repositories)Compounds (repositories) informatics (public database)informatics (public database) cell linescell lines screening servicesscreening services Natural Products Natural Products

Development Development formulation formulation In vivoIn vivo testing testing PharmacologyPharmacology toxicologytoxicology

Rapid Access to Intervention Development (RAID)Rapid Access to Intervention Development (RAID)Clinical proof of principleldquo that a new molecule or approach is a viable candidate for expanded clinical evaluation

Provides NCI Provides NCI resourcesresources including our contract resources including our contract resources- Small- medium scale production- Small- medium scale production- Bulk supply- Bulk supply- GMP manufacturing- GMP manufacturing- formulation- formulation- Toxicology- Toxicology

httpdtpncinihgovdocsraidhttpdtpncinihgovdocsraid

Pre-Clinical through ClinicalPre-Clinical through Clinical

NCI Drug Development GroupNCI Drug Development Group

Cancer Therapy Evaluation Program (CTEP)Cancer Therapy Evaluation Program (CTEP)

Pre-clinical development and clinical development of Pre-clinical development and clinical development of cancer therapeuticscancer therapeutics

National Network of Clinical CentersNational Network of Clinical Centers httpctepcancergovhttpctepcancergov

NCI-FrederickNCI-Frederick

Federal Funded Research and Development Federal Funded Research and Development CenterCenter

Government-Owned Contactor-operated Government-Owned Contactor-operated facilityfacility

Contractor is currently SAIC-Frederick IncContractor is currently SAIC-Frederick Inc

Services and SupportServices and SupportNCI-FrederickNCI-Frederick

biopharmaceutical development program biopharmaceutical development program a high-performance IT center dedicated to biomedical a high-performance IT center dedicated to biomedical

research and informaticsresearch and informatics advanced technology programsadvanced technology programs

genomics genomics proteomics proteomics imaging imaging nanotechnology nanotechnology histopathologyhistopathology molecular biology molecular biology

clinical trial laboratory servicesclinical trial laboratory services

NCI Nanotechnology Characterization NCI Nanotechnology Characterization Laboratory (NCL)Laboratory (NCL)

Characterization of physical attributes pre-clinical Characterization of physical attributes pre-clinical toxicology and efficacy testing of nanoparticles intended toxicology and efficacy testing of nanoparticles intended for cancer therapy imaging and diagnosticsfor cancer therapy imaging and diagnostics

Partners with NIST and the FDAPartners with NIST and the FDA

httpnclcancergovworking_application-processasphttpnclcancergovworking_application-processasp

Check Handout and links for more Check Handout and links for more informationinformation

Description of programDescription of program Eligibility requirementsEligibility requirements Types of servicesTypes of services Application proceduresApplication procedures Intellectual property considerationsIntellectual property considerations Funded projects and outcomesFunded projects and outcomes

QuestionsQuestions

Thomas M Stackhouse PhDThomas M Stackhouse PhD

Assistant DirectorAssistant Director

Technology Transfer CenterTechnology Transfer Center

National Cancer InstituteNational Cancer Institute

stackhotmailnihgovstackhotmailnihgov

NIH Technology Development CoordinatorsNIH Technology Development Coordinators

httpottodnihgovnih_stafftdchtmlhttpottodnihgovnih_stafftdchtml

NCI Developmental Therapeutic Program (DTP) NCI Developmental Therapeutic Program (DTP) provides resources forprovides resources for

DiscoveryDiscovery Compounds (repositories)Compounds (repositories) informatics (public database)informatics (public database) cell linescell lines screening servicesscreening services Natural Products Natural Products

Development Development formulation formulation In vivoIn vivo testing testing PharmacologyPharmacology toxicologytoxicology

Rapid Access to Intervention Development (RAID)Rapid Access to Intervention Development (RAID)Clinical proof of principleldquo that a new molecule or approach is a viable candidate for expanded clinical evaluation

Provides NCI Provides NCI resourcesresources including our contract resources including our contract resources- Small- medium scale production- Small- medium scale production- Bulk supply- Bulk supply- GMP manufacturing- GMP manufacturing- formulation- formulation- Toxicology- Toxicology

httpdtpncinihgovdocsraidhttpdtpncinihgovdocsraid

Pre-Clinical through ClinicalPre-Clinical through Clinical

NCI Drug Development GroupNCI Drug Development Group

Cancer Therapy Evaluation Program (CTEP)Cancer Therapy Evaluation Program (CTEP)

Pre-clinical development and clinical development of Pre-clinical development and clinical development of cancer therapeuticscancer therapeutics

National Network of Clinical CentersNational Network of Clinical Centers httpctepcancergovhttpctepcancergov

NCI-FrederickNCI-Frederick

Federal Funded Research and Development Federal Funded Research and Development CenterCenter

Government-Owned Contactor-operated Government-Owned Contactor-operated facilityfacility

Contractor is currently SAIC-Frederick IncContractor is currently SAIC-Frederick Inc

Services and SupportServices and SupportNCI-FrederickNCI-Frederick

biopharmaceutical development program biopharmaceutical development program a high-performance IT center dedicated to biomedical a high-performance IT center dedicated to biomedical

research and informaticsresearch and informatics advanced technology programsadvanced technology programs

genomics genomics proteomics proteomics imaging imaging nanotechnology nanotechnology histopathologyhistopathology molecular biology molecular biology

clinical trial laboratory servicesclinical trial laboratory services

NCI Nanotechnology Characterization NCI Nanotechnology Characterization Laboratory (NCL)Laboratory (NCL)

Characterization of physical attributes pre-clinical Characterization of physical attributes pre-clinical toxicology and efficacy testing of nanoparticles intended toxicology and efficacy testing of nanoparticles intended for cancer therapy imaging and diagnosticsfor cancer therapy imaging and diagnostics

Partners with NIST and the FDAPartners with NIST and the FDA

httpnclcancergovworking_application-processasphttpnclcancergovworking_application-processasp

Check Handout and links for more Check Handout and links for more informationinformation

Description of programDescription of program Eligibility requirementsEligibility requirements Types of servicesTypes of services Application proceduresApplication procedures Intellectual property considerationsIntellectual property considerations Funded projects and outcomesFunded projects and outcomes

QuestionsQuestions

Thomas M Stackhouse PhDThomas M Stackhouse PhD

Assistant DirectorAssistant Director

Technology Transfer CenterTechnology Transfer Center

National Cancer InstituteNational Cancer Institute

stackhotmailnihgovstackhotmailnihgov

NIH Technology Development CoordinatorsNIH Technology Development Coordinators

httpottodnihgovnih_stafftdchtmlhttpottodnihgovnih_stafftdchtml

Pre-Clinical through ClinicalPre-Clinical through Clinical

NCI Drug Development GroupNCI Drug Development Group

Cancer Therapy Evaluation Program (CTEP)Cancer Therapy Evaluation Program (CTEP)

Pre-clinical development and clinical development of Pre-clinical development and clinical development of cancer therapeuticscancer therapeutics

National Network of Clinical CentersNational Network of Clinical Centers httpctepcancergovhttpctepcancergov

NCI-FrederickNCI-Frederick

Federal Funded Research and Development Federal Funded Research and Development CenterCenter

Government-Owned Contactor-operated Government-Owned Contactor-operated facilityfacility

Contractor is currently SAIC-Frederick IncContractor is currently SAIC-Frederick Inc

Services and SupportServices and SupportNCI-FrederickNCI-Frederick

biopharmaceutical development program biopharmaceutical development program a high-performance IT center dedicated to biomedical a high-performance IT center dedicated to biomedical

research and informaticsresearch and informatics advanced technology programsadvanced technology programs

genomics genomics proteomics proteomics imaging imaging nanotechnology nanotechnology histopathologyhistopathology molecular biology molecular biology

clinical trial laboratory servicesclinical trial laboratory services

NCI Nanotechnology Characterization NCI Nanotechnology Characterization Laboratory (NCL)Laboratory (NCL)

Characterization of physical attributes pre-clinical Characterization of physical attributes pre-clinical toxicology and efficacy testing of nanoparticles intended toxicology and efficacy testing of nanoparticles intended for cancer therapy imaging and diagnosticsfor cancer therapy imaging and diagnostics

Partners with NIST and the FDAPartners with NIST and the FDA

httpnclcancergovworking_application-processasphttpnclcancergovworking_application-processasp

Check Handout and links for more Check Handout and links for more informationinformation

Description of programDescription of program Eligibility requirementsEligibility requirements Types of servicesTypes of services Application proceduresApplication procedures Intellectual property considerationsIntellectual property considerations Funded projects and outcomesFunded projects and outcomes

QuestionsQuestions

Thomas M Stackhouse PhDThomas M Stackhouse PhD

Assistant DirectorAssistant Director

Technology Transfer CenterTechnology Transfer Center

National Cancer InstituteNational Cancer Institute

stackhotmailnihgovstackhotmailnihgov

NIH Technology Development CoordinatorsNIH Technology Development Coordinators

httpottodnihgovnih_stafftdchtmlhttpottodnihgovnih_stafftdchtml

NCI-FrederickNCI-Frederick

Federal Funded Research and Development Federal Funded Research and Development CenterCenter

Government-Owned Contactor-operated Government-Owned Contactor-operated facilityfacility

Contractor is currently SAIC-Frederick IncContractor is currently SAIC-Frederick Inc

Services and SupportServices and SupportNCI-FrederickNCI-Frederick

biopharmaceutical development program biopharmaceutical development program a high-performance IT center dedicated to biomedical a high-performance IT center dedicated to biomedical

research and informaticsresearch and informatics advanced technology programsadvanced technology programs

genomics genomics proteomics proteomics imaging imaging nanotechnology nanotechnology histopathologyhistopathology molecular biology molecular biology

clinical trial laboratory servicesclinical trial laboratory services

NCI Nanotechnology Characterization NCI Nanotechnology Characterization Laboratory (NCL)Laboratory (NCL)

Characterization of physical attributes pre-clinical Characterization of physical attributes pre-clinical toxicology and efficacy testing of nanoparticles intended toxicology and efficacy testing of nanoparticles intended for cancer therapy imaging and diagnosticsfor cancer therapy imaging and diagnostics

Partners with NIST and the FDAPartners with NIST and the FDA

httpnclcancergovworking_application-processasphttpnclcancergovworking_application-processasp

Check Handout and links for more Check Handout and links for more informationinformation

Description of programDescription of program Eligibility requirementsEligibility requirements Types of servicesTypes of services Application proceduresApplication procedures Intellectual property considerationsIntellectual property considerations Funded projects and outcomesFunded projects and outcomes

QuestionsQuestions

Thomas M Stackhouse PhDThomas M Stackhouse PhD

Assistant DirectorAssistant Director

Technology Transfer CenterTechnology Transfer Center

National Cancer InstituteNational Cancer Institute

stackhotmailnihgovstackhotmailnihgov

NIH Technology Development CoordinatorsNIH Technology Development Coordinators

httpottodnihgovnih_stafftdchtmlhttpottodnihgovnih_stafftdchtml

Services and SupportServices and SupportNCI-FrederickNCI-Frederick

biopharmaceutical development program biopharmaceutical development program a high-performance IT center dedicated to biomedical a high-performance IT center dedicated to biomedical

research and informaticsresearch and informatics advanced technology programsadvanced technology programs

genomics genomics proteomics proteomics imaging imaging nanotechnology nanotechnology histopathologyhistopathology molecular biology molecular biology

clinical trial laboratory servicesclinical trial laboratory services

NCI Nanotechnology Characterization NCI Nanotechnology Characterization Laboratory (NCL)Laboratory (NCL)

Characterization of physical attributes pre-clinical Characterization of physical attributes pre-clinical toxicology and efficacy testing of nanoparticles intended toxicology and efficacy testing of nanoparticles intended for cancer therapy imaging and diagnosticsfor cancer therapy imaging and diagnostics

Partners with NIST and the FDAPartners with NIST and the FDA

httpnclcancergovworking_application-processasphttpnclcancergovworking_application-processasp

Check Handout and links for more Check Handout and links for more informationinformation

Description of programDescription of program Eligibility requirementsEligibility requirements Types of servicesTypes of services Application proceduresApplication procedures Intellectual property considerationsIntellectual property considerations Funded projects and outcomesFunded projects and outcomes

QuestionsQuestions

Thomas M Stackhouse PhDThomas M Stackhouse PhD

Assistant DirectorAssistant Director

Technology Transfer CenterTechnology Transfer Center

National Cancer InstituteNational Cancer Institute

stackhotmailnihgovstackhotmailnihgov

NIH Technology Development CoordinatorsNIH Technology Development Coordinators

httpottodnihgovnih_stafftdchtmlhttpottodnihgovnih_stafftdchtml

NCI Nanotechnology Characterization NCI Nanotechnology Characterization Laboratory (NCL)Laboratory (NCL)

Characterization of physical attributes pre-clinical Characterization of physical attributes pre-clinical toxicology and efficacy testing of nanoparticles intended toxicology and efficacy testing of nanoparticles intended for cancer therapy imaging and diagnosticsfor cancer therapy imaging and diagnostics

Partners with NIST and the FDAPartners with NIST and the FDA

httpnclcancergovworking_application-processasphttpnclcancergovworking_application-processasp

Check Handout and links for more Check Handout and links for more informationinformation

Description of programDescription of program Eligibility requirementsEligibility requirements Types of servicesTypes of services Application proceduresApplication procedures Intellectual property considerationsIntellectual property considerations Funded projects and outcomesFunded projects and outcomes

QuestionsQuestions

Thomas M Stackhouse PhDThomas M Stackhouse PhD

Assistant DirectorAssistant Director

Technology Transfer CenterTechnology Transfer Center

National Cancer InstituteNational Cancer Institute

stackhotmailnihgovstackhotmailnihgov

NIH Technology Development CoordinatorsNIH Technology Development Coordinators

httpottodnihgovnih_stafftdchtmlhttpottodnihgovnih_stafftdchtml

Check Handout and links for more Check Handout and links for more informationinformation

Description of programDescription of program Eligibility requirementsEligibility requirements Types of servicesTypes of services Application proceduresApplication procedures Intellectual property considerationsIntellectual property considerations Funded projects and outcomesFunded projects and outcomes

QuestionsQuestions

Thomas M Stackhouse PhDThomas M Stackhouse PhD

Assistant DirectorAssistant Director

Technology Transfer CenterTechnology Transfer Center

National Cancer InstituteNational Cancer Institute

stackhotmailnihgovstackhotmailnihgov

NIH Technology Development CoordinatorsNIH Technology Development Coordinators

httpottodnihgovnih_stafftdchtmlhttpottodnihgovnih_stafftdchtml

QuestionsQuestions

Thomas M Stackhouse PhDThomas M Stackhouse PhD

Assistant DirectorAssistant Director

Technology Transfer CenterTechnology Transfer Center

National Cancer InstituteNational Cancer Institute

stackhotmailnihgovstackhotmailnihgov

NIH Technology Development CoordinatorsNIH Technology Development Coordinators

httpottodnihgovnih_stafftdchtmlhttpottodnihgovnih_stafftdchtml