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Nucleic Acid Quality Control Solutions for Any ThroughputAgilent Automated Electrophoresis Portfolio
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Go above and beyond with the Agilent Automated Electrophoresis portfolio, a collection of instruments designed for the quantitative and qualitative analysis of nucleic acids. With automated options for ultralow to ultrahigh throughputs, fast run times, and a broad variety of assays and kits, the automated electrophoresis systems enable accurate, efficient, and reliable quality control (QC) for any application.
Exceed Your Expectations
Agilent TapeStation systems – Provide easy-to-use solutions for the rapid and precise evaluation of DNA and RNA samples in as little as one to two minutes per sample. These systems are compatible with ultralow- to high-throughput workflows and include:
– 4150 TapeStation system: analyze up to 16 samples at a time for low-throughput laboratories
– 4200 TapeStation system: run up to 96 samples at a time for high-throughput workflows
Agilent Fragment Analyzer systems – Utilize parallel capillary electrophoresis for nucleic acid analysis in a variety of applications and throughputs and include:
– 5200 Fragment Analyzer system: perform low- to medium-throughput workflows with a 12-capillary array
– 5300 Fragment Analyzer system: select either a 48- or 96-capillary array for high- to ultrahigh-throughput workflows
– 5400 Fragment Analyzer system: get complete robotic integration with a 96-capillary array, enabling ultrahigh-throughput workflows
Agilent 2100 Bioanalyzer system – Separate DNA, RNA, and protein samples with lab-on-a-chip electrophoresis. This well-established system is adaptable to virtually any QC workflow
Agilent Femto Pulse system – Analyze high molecular weight genomic DNA (gDNA) in 1.5 hours and enable ultrasensitive detection of DNA and RNA with the only automated pulsed-field instrument on the market
Agilent ZAG DNA Analyzer system – Achieve quick and efficient analysis of DNA fragments with this ultrahigh-throughput platform
Agilent Oligo Pro II system – Accelerate QC of ssDNA and ssRNA oligonucleotides with rapid, reliable, and dye-free analysis of ssDNA and ssRNA oligonucleotides
With a large range of throughputs and applications, the Agilent Automated Electrophoresis portfolio provides accurate and trusted solutions to give you objective, reliable QC metrics for any sample at any throughput.
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Our Automated Electrophoresis portfolio is a compilation of instruments that are designed for advanced quality control of nucleic acid samples. Whether you are evaluating a few samples at a time, or need to analyze thousands of samples every day, we have an instrument for your needs. Use the graphic below to find the system best tailored to your workflows and start saving time, money, and valuable resources.
An Instrument for Any Throughput Need
Ultra-low
Low
Medium
High
Ultrahigh
2100 Bioanalyzer
4150 TapeStation
5200 Fragment Analyzer
and Femto Pulse4200 TapeStation
5300 Fragment Analyzer
ZAG DNA Analyzer
5400 Fragment Analyzer
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TapeStation Systems
The TapeStation systems accelerate nucleic acid analyses and minimize time to results with easy-to-use ScreenTape technology. The automated workflow enables analysis of 1 to 96 samples in as little as one to two minutes each, letting your lab focus on the work that matters.
Key system benefits include: – A simple workflow, allowing you to load a ScreenTape
device and your samples, then let the instrument do the rest
– Flexible ScreenTape technology, enabling you to save partially used ScreenTape devices for later use, resulting in a constant cost-per-sample
– Comprehensive compliance services (IQ/OQ)
Analyze a wide range of sample types for different applications including:
– NGS libraries
– cfDNA
– gDNA
– Total RNA
– PCR fragment analysis
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With two different systems and complete assay compatibility between instruments, the TapeStation systems are easily adaptable to the workflow of any lab.
The 4150 TapeStation system is ideal for ultralow-throughput labs and permits the analysis of up to 16 samples.
The 4200 TapeStation system provides higher throughput for running up to 96 samples with constant costs per sample.
*Assay dependent
*Assay dependent
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Fragment Analyzer Systems
The Fragment Analyzer systems break through analytical bottlenecks and streamline nucleic acid analysis workflows, providing researchers with the results they need, when they need them. Automated parallel capillary electrophoresis allows for analysis of as few as 12 to as many as 96 samples per run without user intervention.
Key system benefits include: – The versatility of interchangeable arrays, allowing users
to choose between speed and resolution to fit the changing needs of any lab
– The ability to load up to three 96-well plates and process in any order
– The flexibility to house two different gel matrices to analyze different sample types unattended
Analyze a wide range of sample types for different applications including:
– NGS libraries
– cfDNA
– gDNA
– Total RNA
– Small RNA
– MicroRNA
– PCR fragment analysis
– Multiplex PCR
– Restriction digest
– Microsatellites
– CRISPR
– Large fragment DNA
– TILLiNG
– Plasmid DNA
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With three different models, the Fragment Analyzer systems are compatible with the workflow of any lab.
The 5200 Fragment Analyzer system uses a 12-capillary array and is ideal for low to medium-throughput labs.
The 5300 Fragment Analyzer system offers higher throughput and can be run with either a 48- or 96-capillary array.
The 5400 Fragment Analyzer system is an ultrahigh-throughput system that uses a 96-capillary array. It was designed to fully integrate into most robotic systems using a tested Application Program Interface (API), enabling the analysis of 2400 samples per day.
*Kit specific
*Kit specific
*Kit specific
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Bioanalyzer System
Featured in more than 60,000 citations, the 2100 Bioanalyzer system is a well-established system that fits into virtually any QC workflow. High-sensitivity QC of up to 12 DNA, RNA, or protein samples improves lab efficiency with minimal input requirements, allowing the conservation of precious samples for the work that matters.
Key system benefits include: – A broad variety of assays for nucleic acid and protein analysis, suitable for a wide
range of applications
– The advantage of a widely accepted QC tool recommended by major NGS vendors for library QC and determination of nucleic acid integrity
– Services and software features enabling 21 CFR Part 11 compliance services
Analyze a wide range of sample types for different applications including:
– NGS libraries
– Total RNA
– Small RNA
– MicroRNA
– Messenger RNA
– PCR fragment analysis
– Multiplex PCR
– Restriction digest
– Microsatellites
– Antibodies
– Proteins
*Assay dependent
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Femto Pulse System
The Femto Pulse system shatters nucleic acid analysis barriers, giving researchers unparalleled sensitivity to analyze large nucleic acid fragments in about 1.5 hours. An automated pulsed-field power supply allows the separation of DNA up to 165 kb. The optimized optical platform enables 10 times higher sensitivity for nucleic acid smear analysis (up to 100 times higher for fragment analysis) and offers detection capabilities down to 50 fg/µL.
Key system benefits include: – A rapid workflow, allowing quick and accurate quantitation, qualification, and
sizing of DNA fragments up to 165 kb in about 1.5 hours
– Enhanced sensitivity for the detection of DNA fragments down to 50 fg/µL and quantitation of a single cell’s worth of gDNA or total RNA
– Minimal input requirements, enabling conservation of sample for downstream applications
Analyze a wide range of sample types for different applications including:
– NGS libraries
– Long-read sequencing libraries
– cfDNA
– gDNA
– Total RNA
– Small RNA
– Messenger RNA
– High molecular weight DNA
– BACs
*Kit specific
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ZAG DNA Analyzer System
The ZAG DNA Analyzer system removes analytic bottlenecks and expedites DNA fragment analysis workflows, giving researchers the ability to painlessly screen thousands of DNA fragments per day. Designed for analysis of PCR fragments, microsatellites, and restriction enzyme digest products, this system is essential for high-throughput facilities focused on qualitative DNA fragment analysis.
Key system benefits include: – A smooth, rapid workflow enables loading of 864 samples at once and the
separation of over 4,600 samples in 24 hours
– Intuitive software features, including batch processing, allowing analysis of over 100 sample plates simultaneously with advanced sample flagging
– High-resolution separation, giving researchers the ability to distinguish and size DNA fragments within 3 bp of each other
Analyze a wide range of sample types for different applications including:
– PCR fragment analysis
– Restriction digest
– Microsatellites
*Kit specific
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Oligo Pro II System
The Oligo Pro II system delivers confidence in your oligonucleotides, ensuring optimal downstream performance of ssDNA and ssRNA oligos. 12-, 24-, and 96-capillary array options provide flexible throughput with results ready in only about 1 hour, while direct UV detection removes the need for dye labeling.
Key system benefits include: – Automated operation, enabling analysis of 288 samples without user intervention
– Adaptable throughput, providing separation of 12, 24, or 96 samples per run
– Dye-free direct UV detection of samples with single-base resolution through 60-mers
Analyze a wide range of sample types for different applications including:
– ssDNA oligos
– ssRNA oligos
Learn more: www.agilent.com/genomics/automated-electrophoresis
Buy online: www.agilent.com/chem/store
U.S. and Canada 1-800-227-9770 [email protected]
Europe [email protected]
Asia Pacific [email protected]
For Research Use Only. Not for use in diagnostic procedures.
This information is subject to change without notice.
© Agilent Technologies, Inc. 2020 Published in the USA, April 1, 2020 5994-1817EN
