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Neurotransmission of signals

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Describe the steps in neurotransmission. Describe the ionic basis for neurotransmitter release. List the major neurotransmitters and describe their mode of action. Describe the basic organization of the nervous system. Neurotransmission of signals. Conduction of Action Potentials. - PowerPoint PPT Presentation

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  • Neurotransmission of signalsDescribe the steps in neurotransmission. Describe the ionic basis for neurotransmitter release.List the major neurotransmitters and describe their mode of action.Describe the basic organization of the nervous system.

  • Conduction of Action PotentialsFigure 8-14a: Conduction of action potentials

  • Mechanism of Vg Na+ channelsFigure 8-10: Model of the voltage-gated channel Na+

  • Neurocrines

  • Neurocrines

  • Possible mechanisms of NT action

  • Neurotransmitters and ReceptorsACh receptor (cholinergic) nicotinicmuscarinicNE and E receptor (adrenergic)1 and 2 (alpha)1 and 2 (beta)

  • Acetylcholinenicotinic receptor is a Na+ / K+channel

    muscarinic receptor is a G-protein coupled receptor that links to 2nd messenger; five known forms

  • http://www.blackwellscience.com/matthews/neurotrans.html

  • Acetylcholine synthesisFigure 8-21: Synthesis and recycling of acetylcholine at the synapse

  • Norepinephrine/Epinephrineadrenergic receptors, alpha and beta are G-protein coupled receptors, linked to 2nd messengers

  • Neurotransmission of signalsDescribe the basic organization of the nervous system. List the steps in neurotransmission.

  • Organization of the Nervous SystemText Figure 8-1

  • http://biology.udayton.edu/Courses/BIO415/StudyGuides/images/05/Fig11_Part_2_Movie.gif

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