National Specialist Dermatopathology EQA Scheme Circulation K

National Specialist National Specialist Dermatopathology EQA Dermatopathology EQA

SchemeScheme

Circulation KCirculation K

Case 165Case 165

Female aged 7Female aged 7

Skin dorsum left footSkin dorsum left foot

Most popular diagnosis: Most popular diagnosis:

Cellular blue naevus/benign combined Cellular blue naevus/benign combined naevusnaevus

Case 166Case 166

Female aged 58. Female aged 58.

30 year history of hyperkeratotic 30 year history of hyperkeratotic plaques on the scalp and face ? plaques on the scalp and face ? Darier's disease.Darier's disease.

Most popular diagnosis:Most popular diagnosis:

Darier’s diseaseDarier’s disease

Case 167Case 167

Female aged 26. Blue naevus.Female aged 26. Blue naevus. Skin lesion right ear.Skin lesion right ear.

Skin fragment 9 x 5 mm with a Skin fragment 9 x 5 mm with a central dark lesion 5 x 5 mm.central dark lesion 5 x 5 mm.

Some, but not all, lesional cells Some, but not all, lesional cells HMB45 positive.HMB45 positive.

Withdrawn from scoringWithdrawn from scoring

Case 168Case 168

Female aged 31. Female aged 31. Four week history of red plaques on Four week history of red plaques on

thighs, feels hot ? Chilblains. Works thighs, feels hot ? Chilblains. Works outside washing cars in jeans.outside washing cars in jeans.

Lesions appeared during cold weather & Lesions appeared during cold weather & snow in Dec 2010.snow in Dec 2010.

Immuno : ANA negative.Immuno : ANA negative.


Perniosis / cold panniculitisPerniosis / cold panniculitis

Case 169Case 169


Psoriasiform rash on trunk and limbs.Psoriasiform rash on trunk and limbs.


PsoriasisPsoriasis

Case 170Case 170

Male aged 70. Male aged 70.

? Bowen's disease.? Bowen's disease.

Specimen: ExcisionSpecimen: Excision

Immuno : Melan A (-), S100 (-), EMA (+), CK20 (-)Immuno : Melan A (-), S100 (-), EMA (+), CK20 (-)


Paget’s diseasePaget’s disease

Case 171Case 171


Mole lower back - increased in size over 2-Mole lower back - increased in size over 2-6 months.6 months.

Skin ellipse 23 x 13 x 5 mm. Skin ellipse 23 x 13 x 5 mm. Surface Surface bears a central variably pigmented lesion bears a central variably pigmented lesion measuring 13 mm maximum with an measuring 13 mm maximum with an irregular outline. Slightly raised one end irregular outline. Slightly raised one end

Most popular diagnosisMost popular diagnosis

Benign compound naevus +/- with low Benign compound naevus +/- with low grade dysplasiagrade dysplasia

Case 172Case 172


Raised papular plaque, left backRaised papular plaque, left back ? G. Annulare? G. Annulare

Macro: 6mm punch biopsyMacro: 6mm punch biopsy


Granuloma annulareGranuloma annulare

Case 173Case 173

Female age 43. Female age 43. ?erythema nodosum, front of right leg. ?erythema nodosum, front of right leg. O/E raised red nodules over shins. O/E raised red nodules over shins. HIV positive. TB not proved on lymph HIV positive. TB not proved on lymph

node culture. node culture. Previous biopsy showed similar Previous biopsy showed similar

features. features. T-spot test positiveT-spot test positive


Erythema nodosumErythema nodosum

Case 174Case 174

Male aged 64 years. Male aged 64 years.

8 mm warty lesion lateral aspect of 8 mm warty lesion lateral aspect of

right eyebrow of 10 years duration.right eyebrow of 10 years duration.


Syringocystadenoma papilliferumSyringocystadenoma papilliferum

The End!The End!

Thank you!Thank you!

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National Specialist Dermatopathology EQA Scheme Circulation K