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Mazor Corporate Presentation NASDAQ, TASE: MZOR September, 2018 1

NASDAQ, TASE: MZOR September, 2018 · This presentation contains “forward-looking statements” within the meaning of the Private Securities Litigation Reform Act of 1995 and other

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Page 1: NASDAQ, TASE: MZOR September, 2018 · This presentation contains “forward-looking statements” within the meaning of the Private Securities Litigation Reform Act of 1995 and other

Mazor Corporate PresentationNASDAQ, TASE: MZOR

September, 2018

1

Page 2: NASDAQ, TASE: MZOR September, 2018 · This presentation contains “forward-looking statements” within the meaning of the Private Securities Litigation Reform Act of 1995 and other

This presentation contains “forward-looking statements” within the meaning of the Private Securities Litigation

Reform Act of 1995 and other securities laws. Forward-looking statements are not historical facts, and are based

upon management’s current expectations, beliefs and projections, many of which, by their nature, are inherently

uncertain. Such expectations, beliefs and projections are expressed in good faith. However, there can be no

assurance that management’s expectations, beliefs and projections will be achieved and actual results may differ

materially from what is expressed in or indicated by the forward-looking statements. Forward-looking statements are

subject to risks and uncertainties that could cause actual performance or results to differ materially from those

expressed in the forward-looking statements, including risks detailed in Mazor Robotics Ltd.’s (“Mazor Robotics” or

the “Company”) annual reports on Form 20-F filed with the U.S. Securities and Exchange Commission. The following

solutions are not yet cleared for use: Mazor X Stealth Edition, Stealth Navigation, Guidewireless

Forward-looking statements speak only as of the date the statements are made. The Company assumes no

obligation to update forward-looking statements to reflect actual results, subsequent events or circumstances,

changes in assumptions or changes in other factors affecting forward-looking information except to the extent

required by applicable securities laws. If the Company does update one or more forward-looking statements, no

inference should be drawn that the Company will make additional updates with respect thereto or with respect to

other forward-looking statements.

FORWARD LOOKING STATEMENT

2

Page 3: NASDAQ, TASE: MZOR September, 2018 · This presentation contains “forward-looking statements” within the meaning of the Private Securities Litigation Reform Act of 1995 and other

3

Our MissionMazor as a growing global innovation leader focused on

improving patients’ outcomes throughout the care

continuum, by developing advanced, data-enabled,

image-based robotic products with universal

connectivity in multiple surgical fields.

Page 4: NASDAQ, TASE: MZOR September, 2018 · This presentation contains “forward-looking statements” within the meaning of the Private Securities Litigation Reform Act of 1995 and other

Mazor Today

4

● Mazor Core ™ technology with product

portfolio and three generations of commercial

products

● Supporting and serving 200+ installations and

spine programs globally

● 36,000+ Patients, 100s of surgeons, wide

spectrum of procedures

● Strategic partnership with Medtronic

(Mazor X in spine)

● Successful initiative in ASC market (Ren)

● 55+ peer-reviewed articles and strong

evidence of improved patient outcomes

● Ramping up Production

Page 5: NASDAQ, TASE: MZOR September, 2018 · This presentation contains “forward-looking statements” within the meaning of the Private Securities Litigation Reform Act of 1995 and other

Mazor Robotic Guidance Systems

Predictability, Precision and Efficiency through Innovation

5

1. Planning 2. Guided Execution 3. Intra Op Verification

Value creation through robotic workflow

Page 6: NASDAQ, TASE: MZOR September, 2018 · This presentation contains “forward-looking statements” within the meaning of the Private Securities Litigation Reform Act of 1995 and other

6

The Mazor Core Technology is the collaboration of

four key technologies in Mazor's systems to provide

predictable, efficient and precise surgical procedures.

Page 7: NASDAQ, TASE: MZOR September, 2018 · This presentation contains “forward-looking statements” within the meaning of the Private Securities Litigation Reform Act of 1995 and other

• The advanced anatomy recognition engine reads images and recognizes anatomical features based on advanced and proprietry algorithms.

• The engine is fundamental for planning and serves as the underlying technology for features such as vertebral segmentation, image registration and alignment calculations.

• Set of biocompatible devices that rigidly affix the robotic system/arm to the patient’s skeletal anatomy during surgery, ensuring precision through a stable, solid connection.

• This unique feature maintains patient-machine unity during the operation and is a major contributor to accuracy.

• Sophisticated registration tool with the ability to analyze and match images from different modalities and body positions, e.g. pre-op CT with intra-op fluoroscopy.

• Each vertebra is registered independently of the others and irrespective of modality, date of the image, or patient position.

Mazor Core

• 3D analytics and virtual tools developed to determine procedure goals and surgical plan. The suite of tools allow creation of a “surgical blueprint” separating the planning from the actual surgery.

• During surgery, the surgeon executes the plan as an efficient and predictable procedure with no anatomical surprises. Implants are pre-selected and prepped, the team knows what to expect.

7

Surgical Planning Suite Cross-modality image registrationAnatomy Recognition Engine Patient Connection Platform

Page 8: NASDAQ, TASE: MZOR September, 2018 · This presentation contains “forward-looking statements” within the meaning of the Private Securities Litigation Reform Act of 1995 and other

Robotics and Navigation in One Integrated System

Mazor X Stealth Edition*

8

Features

• Robotic Guidance and Integrated Stealth Navigation

• Robotic Guided implants

• Sophisticated tools for Construct Planning

• Real-Time reconciliationwith Plan

• Mazor Core feature set

• Assures Performance, closes the surgical loop

• Simplified workflow

• Holistic and personalized patient planning

• Real time verification of surgical goals

• Proven clinical benefits

Benefits

*Not available for sale in the US, pending FDA clearance

Page 9: NASDAQ, TASE: MZOR September, 2018 · This presentation contains “forward-looking statements” within the meaning of the Private Securities Litigation Reform Act of 1995 and other

Renaissance Strategy

U.S. Focus on Ambulatory Surgical Centers

• Business Model:• Cost-sensitive market penetration and development

• ~1000+ sites Addressable Market

• Successful initial efforts with growing number of installations and

usage

• Global Sales Organization • Direct activities in the United States

• Active distributors in China, Taiwan, Australia, Thailand, Vietnam,

Germany

• Technology• Mazor Core + Brain

• 10% of accounts include Renaissance Brain

9

Page 10: NASDAQ, TASE: MZOR September, 2018 · This presentation contains “forward-looking statements” within the meaning of the Private Securities Litigation Reform Act of 1995 and other

Accelerated Clinical Utilization

Driving MIS and Serving Patients

10

"If you do spine surgery for a living, this will come naturally to you...This is the future of spinal surgery."

Isador Lieberman, MD, MBA, FRCSC, Plano, Texas, USA

US Installed Base and Procedure Breakdown

59%57%

55% 49%

49%50% 50%

41%

43%

45%

51%

51%

50%50%

-10

10

30

50

70

90

110

130

150

0

500

1,000

1,500

2,000

2,500

3,000

H1.2012 H1.2013 H1.2014 H1.2015 H1.2016 H1.2017 H1 2018

# In

stal

led

Bas

e

# P

roce

du

res

Open MIS Installed base

Page 11: NASDAQ, TASE: MZOR September, 2018 · This presentation contains “forward-looking statements” within the meaning of the Private Securities Litigation Reform Act of 1995 and other

Evidence-based Medicine

From Accuracy to Outcomes

11

Reduction in Complications and Revisions (1)

___________________________1. Based on published data: Cannestra, e-poster NASS 2014; Kantelhardt, ESJ 2011; Ringel, ESJ 2012, Roser, 2013.

2. Freehand represents the average fluoro radiation exposure during a freehand operation as a baseline for comparison to Renaissance only.

Reduction in Exposure to IntraOp Radiation (2)

Consistent Accuracy with Improved Outcomes18.1%

5.8%5.2%

0.9%

1 2

I have been doing minimally-invasive surgery since 1999. Mazor Robotics Renaissance®'s revolutionary approach to spinal surgery has transformed my practice so I no longer need to do any open thoracic and lumbar surgery..

Dr. Thomas Sweeney,, Orthopaedic Surgeon, FL

Page 12: NASDAQ, TASE: MZOR September, 2018 · This presentation contains “forward-looking statements” within the meaning of the Private Securities Litigation Reform Act of 1995 and other

Evidence-Based Medicine

MIS-ReFRESH Prospective Study

(Presented at IMAST 2018)

Significantly fewer complications in robotic arm

• Compared to fluoro-guided, robotic-guided surgeries were at 3.1times LOWER risk for a complication

Significantly fewer revisions in robotic arm

• Compared to fluoro-guided, robotic-guided surgeries were at 14.7 times LOWER risk for a revision

79% less fluoro time/screw in robotic arm

Significantly fewer complications and revisions in robotic arm also in

single level cases

Caveats:

• Interim report – only 110 control patients

• Only 2 surgeons in control arm

• Average Follow up 1.3 +0.8 years in robotic and control arm

• High event rate in fluoro-guided arm

12

Kaplan-Meier CurveComplication Free “Survival”

Page 13: NASDAQ, TASE: MZOR September, 2018 · This presentation contains “forward-looking statements” within the meaning of the Private Securities Litigation Reform Act of 1995 and other

MIS ReFRESH Prospective Study of Mazor Core Technology

Patient Self-Evaluations

13

P=0.005

RO=101FH=26

RO=108FH=30P=0.024

Back Pain Oswestry Disability Index

Elapsed Time Post-Op (Months)

Pain

Inte

nsi

ty

Elapsed Time Post-Op (Months)6 120 6 120

Dis

abili

ty In

dex

60% reduction in robotic arm 48% reduction in robotic arm

Page 14: NASDAQ, TASE: MZOR September, 2018 · This presentation contains “forward-looking statements” within the meaning of the Private Securities Litigation Reform Act of 1995 and other

Business Model

Three Revenue Pillars

14

Capital Sales

Mazor X & Upgrades Distributor Sales

Renaissance Direct Sales

Per Case Revenue

Disposable Kits

Synergy fee revenue:* (*) under certain conditions

Per System Revenue

Annual Service revenues

Page 15: NASDAQ, TASE: MZOR September, 2018 · This presentation contains “forward-looking statements” within the meaning of the Private Securities Litigation Reform Act of 1995 and other

H1 2018 Financial and Operating Highlights

• Robotic guidance systems sold in the first half of 2018 increased 32% over the first half of 2017

➢ Q1 – increased by 42%

➢ Q2 – increased by 25%

• Significant majority of systems sold and installed were to

US customers

• H1/2018 financial performance and binding commitments

for the Mazor X Stealth Edition position Mazor for revenue

growth in H2 2018 compared to the H1 2018

15

0

5000

10000

15000

20000

25000

30000

H1.2017 H1.2018

Revenue Growth

Systems Disposables, Service and Others

Page 16: NASDAQ, TASE: MZOR September, 2018 · This presentation contains “forward-looking statements” within the meaning of the Private Securities Litigation Reform Act of 1995 and other

Revenue Breakdown

Year Ended December, 2017

16

Gross margin

74% 70% 71%68% 57% 51%

54%

57%

26% 30%

29%

32% 43%49%

46%

43%

$0

$10,000

$20,000

$30,000

$40,000

$50,000

$60,000

$70,000

Disposables, Service and Others

Systems

$36,379

$19,983 $21,208

$5,904

$12,175

$26,096

$64,947

$3,973

79%79%76%68%76% 78% 72% 64%

Page 17: NASDAQ, TASE: MZOR September, 2018 · This presentation contains “forward-looking statements” within the meaning of the Private Securities Litigation Reform Act of 1995 and other

Income Statement

17

($ in thousands) 2017 2016 2018 2017

Revenue $64,947 $36,379 $28,745 $27,174

Cost of sales $23,684 $10,330 $12,272 $8,875

Gross Profit $41,263 $26,049 $16,473 $18,299

% margin 64% 72% 57% 67%

Operating Expenses

Research and development, net $8,192 $5,736 $5,069 $4,034

Selling and marketing, net $39,499 $33,637 $12,288 $20,209

General and administrative $7,375 $5,697 $4,442 $3,657

Total operating expenses $55,066 $45,070 $21,799 $27,900

% of revenue 85% 124% 76% 103%

Loss from operations ($13,803) ($19,021) ($5,326) ($9,601)

Net loss ($12,419) ($18,668) ($5,118) ($8,908)

Income Statement

Year Ended December 31, 6 Months Ended June 30,

Page 18: NASDAQ, TASE: MZOR September, 2018 · This presentation contains “forward-looking statements” within the meaning of the Private Securities Litigation Reform Act of 1995 and other

Balance Sheet

18

As of June 30, As of December 31,

($ in thousands) 2018 2017

Assets (Unaudited) (Audited)

Cash and Cash equivalent $37,475 $46,376

Short-term investments $66,796 $56,708

Trade receivables $9,401 $5,460

Other accounts receivable $2,936 $2,054

Inventory $7,130 $7,864

Total current assets $123,738 $118,462

Total non-current assets $11,233 $12,534

Total Assets $134,971 $130,996

Current liabilities $16,858 $16,819

Total non-current liabilities $454 $414

Equity $117,659 $113,763

Total liabilities and Equity $134,971 $130,996

Consolidated Statements of Financial Position

Page 19: NASDAQ, TASE: MZOR September, 2018 · This presentation contains “forward-looking statements” within the meaning of the Private Securities Litigation Reform Act of 1995 and other

Mazor Robotics

2018

19

Leverage RoboticsSpine and Out-of-Spine

Ambulatory Surgery CenterStrategy for the Renaissance

Strategic Partnershipwith Medtronic for Mazor X