M/s. PRANSHAV HEALTH CARE - Welcome to Environment€¦ · FOR TREATMENT OF HIV INFECTION 17 Darunavir ANTHRAQUINONE (FOR TREATMENT OF OSTEOARTHRITIS) 18 Diacerein ANTI-HYPERTENSIVE

PROJECT PRE-FEASIBILITY REPORT

AND

ENVIRONMENT MANAGEMENT PLAN

ON

EXPANSION PROJECT

OF

Manufacturing of Pharma Intermediates And

Pharmaceutical Product

OF

M/s. PRANSHAV HEALTH CARE LOCATED AT:

Plot No. 824/16, Near Metco roof,

GIDC, Jhagadi-393110,Dist: Bharuch,

State: Gujarat.

CONTENTS

Sr. No. Particulars Page No.

1 EXECUTIVE SUMMARY 1-5

2 INTRODUCTION 5

2.1 The Project 5

2.2 Project Proponent 20

2.3 Nature of project 21

2.4 Market Feasibility 21

3 PROJECT DESCRIPTION 21

3.1 Type of Project 21

3.2 Project Location 21

3.3 Site selection 24

3.4 Neighbouring Industries 24

3.5 Size of project 25

3.6 Process Technology 25

3.7 Raw material 25

3.8 Resource Optimization/Recycling And Reuse

25

3.9 Resource requirement 26

3.9.1 Land 26

3.9.2 Building 27

3.9.3 Power and Fuel 27

3.9.4 Water 27

3.8.5 Man power 28

3.10 Mitigation measures & EMP 28

3.10.1 Wastewater management

29

3.10.2 Gaseous emission & Control 34


3.10.3 Hazardous /non hazardous waste management 35

3.10.4 Noise control & odour 36

3.10.5 Storage ,handling and transport of Hazardous chemical 36

3.10.6 Health & Safety measures 36

4 SITE ANALYSIS 37

4.1 Connectivity 37

4.2 Land use and land ownership 37

4.3 Existing land use 37

4.4 Existing infrastructure 37

4.5 Soil Classification 37

4.6 Climate data 38

4.7 Social Infrastructure 39

5 PLANNING BRIEF 39

5.1 Planning concept 39

5.2 Population projection 39

5.3 Land use planning 39

5.4 Assessment of infrastructure Demand 39

5.5 Ammentities 40

6 PROPOSED INFRASTRUCTURE 40

6.1 Processing area 40

6.2 Non processing area 40

6.3 Green belt 40

6.4 Social Infrastructure 40

6.5 Connectivity 41

6.6 Drinking water management 41

6.7 Sewage system 41


6.7 Industrial waste managemnt 41

6.9 Solid waste managment 41

6.10 Power requirement & Supply 41

7 REHABILITATION & RESETTLEMENT (R & R) PLAN 41

8 PROJECT SCHEDULE & COST ESTIMATES 42

8.1 Project Implementation Schedule 42

8.2 Estimated project cost 42

9 ANALYSIS OF PROPOSAL 42

M/s. PRANSHAV HEALTH CARE, JHAGADIA

M/s. JYOTI OM CHEMICAL RESEARCH CENTRE PVT. LTD. Page 1

EXECUTIVE SUMMARY

M/s. Pranshav Health Care will engage for manufacturing of Pharma Intermediates and

Pharmaceutical Product at Plot No. 824/16, Near Metco roof, GIDC, Jhagadi-393110,Dist:

Bharuch, State: Gujarat.

As per EIA notification 2006 and its amendment, the proposed project is falling under category

5(f). They have valid CTE No. 70101 for manufacturing Inorganic chemical and valid upto 05-

02-2020. They have proposed to for manufacturing of Pharma Intermediates and Pharmaceutical

Product.

The details of products are given below table.

TABLE: 1

LIST OF PRODUCTS

LIST OF EXISTING PRODUCTS(As per CTE No. 70101)

Sr. No. Product Name Quantity (MT/M)

1 Potassium Chloride 500

(either individual of total 7

product) 2 Potassium fluoride

3 Potassium Bromide

4 Potassium sulphate

5 Calcium sulphate

6 Magnesium sulphate

7 Sodium Bromide

8 Manganese Sulphate 27% solution 50

LIST OF PROPOSED PRODUCTS

Sr. No. Product Name Quantity

(MT/M)

Group A Individual Product

1 Atorvastatin calcium 20.00

2 CH base (Product) 50.00

3 Pentaprazol Sodium 30.00

4 Tertiary Butyl Hydroquinon 40.00

Group B Pharmaceutical Drug 20

PROTON PUMP INHIBITOR (REDUCTION OF

GASTRIC ACID/ ANTACID)

5 Esomeprazole Magnesium Dihydrate

6 Dexlansoprazole

OCULAR CARBONIC ANHYDRASE INHIBITOR(FOR

OPEN ANGLE GLAUCOMA

7 Brinzolamide

8 Dorzolamide HCl

ANTI-DIABETIC DRUGS



9 Canagliflogin

10 Dapagliflozin

11 Vildagliptin

CHEMOTHERAPEUTIC DRUG

12 Capecitabine

ANTIBIOTIC (3RD

GENERATION CEPHALOSPORIN)

13 Cefsulodine Sodium

ANTICOAGULANTS

14 Dabigetran

15 Rivaroxaban

FOR TREATMENT OF PREMATURE EJACULATION

16 Dapoxetine Hydrochloride

FOR TREATMENT OF HIV INFECTION

17 Darunavir

ANTHRAQUINONE (FOR TREATMENT OF

OSTEOARTHRITIS)

18 Diacerein

ANTI-HYPERTENSIVE DRUGS

19 Irbesartan

20 Telmisartan

21 Cilnipine

22 NEBIVOLOL HCL

LEUKOTRIENE ANTAGONIST (FOR TREATMENT

OF BRONCHIAL ASTHMA)

23 Montelukast Sodium

ANTI-FUNGAL DRUGS

24 Posaconazole

ATYPICAL ANTI-PSYCHOTIC (FOR TREATMENT

OF SCHIZOPHRENIA)

25 Quetiapine Hemifumarate

PREVENT OSTEOPOROSIS

26 Risedronate Sodium

ANTIDEPRESSANT DRUGS

27 Vilazodone HCl

28 Agomealtine

ANTI-PSYCHOTIC DRUG

29 Levosulpiride

FOR TREATMENT OF BENIGN PROSTATIC

HYPERPLASIA

30 Tamsulosin HCl

ANTI-EPILEPTIC DRUGS

31 Carbamazepine

32 Levetiracetam

ANTIMUSCARINIC DRUG (FOR TREATMENT OF

OVERACTIVE BLADDER SYNDROME)



33 Fesoterodine

HYPERTENSION

34 Bosentan Monohydrate

FOR TREATMENT OF GOUT

35 Febuxostat

Group C Paraben 50

36 Methyl Paraben

37 Ethyl Paraben

38 Propyl Paraben

39 Butyl Paraben

40 Iso Propyl Paraben

Group d Intermediate 40

41 4- Amino Pyridine

42 Dimethyl Ameno Propiophenone

43 Guaicol

45 Veratrole

46 Diethyl Ethyl Melonate

47 3,5 Dinitrobenzoic acid

48 P - Hydroxy Aceto Phenone

49 2-Mercaptobenzimidazole

50 Bronopol (BP)

51 2 Mercapto 5 Methoxy Benzimimidazone

52 3,5 Dibenzyloxy Acetophenone

53 1(2,3 Dichloro Phenyl) Piperazine

54 1h,1,2,4 Triazole

55 Acebrophylline

56 Lasamide

57 Methyl Nicotinate

58 Fingolimod HCL

59 Cetyl Pyridinium Chloride

60 Ambroxol Hydrochloride

61 1 (2,4 Dichloro Phynyl) 2 (1- Imidazoleylethanol

62 Furoic Acid

Group E Fine Chemicals 200

63 Methyl Acetate

64 Ethyl Acetate

Total 450

LIST OF BY-PRODUCTS

Sr. No. Product Name Quantity (MT/M)

1 Acetic acid 2.56

2 Sodium L (+) Mandelate 9.429

3 Propanoic acid 14.76

4 Trityl chloride 13.014

5 Methane Sulfonic acid 3.156



6 Potassium Bromide 8.139

COST OF PROJECT

The expected cost of project is Rs.505 Lacs. The plot has been purchased by M/s. Pranshav

Health Care from GIDC. The total plot area of the unit is 5700Sq.Mtr. The green belt area will

be 1350 sq.m.

FUEL CONSUMPTION

The proposed unit will use Bio-coal as fuel for Boiler.

ELECTRICITY CONSUMPTION

The unit have electricity from Daxin Gujarat Vij Company Ltd. The existing electricity

consumption is 125 KVA. There will be no changes in Electricity consumption due to Proposed

Expansion.

WATER CONSUMPTION

The source of water will be from GIDC water supply scheme.

As per CTE - 70101, the water consumption for industrial purpose is 7.5KL/day. The water

consumption for the domestic & gardening purpose is 2.5 KL/day.

The water consumption for industrial purpose will 142(fresh) +133(recycle). The unit will use

132 KL/day fresh water and 128 KL/Day recycle. The water consumption for the domestic &

gardening purpose is 10 KL/day fresh water and 5 KL/Day recycle.

WASTE WATER GENERATION

As per CTE- 70101, the industrial waste water generation is NIL and Domestic waste water is

1.5 KL/Day. The domestic effluent is disposed off through soak pit/septic tank.

The industrial waste water generation will be 173 KL/day and domestic waste water will be

7KL/day. The effluent will be treated in ETP .After treatment in ETP send into RO plant and

25KL/day to NCTL.RO permeate is recycled and RO residue is treated by Evaporation.

GASEOUS EMISSION

As per CTE- 70101, the unit is using Bio-coal as fuel in boiler. The unit has installed Multi

Cyclone, and Bag filter as air pollution control system.

The unit will be use Bio-coal as fuel in boiler. The unit will install Multi Cyclone, and Bag filter

as air pollution control system. . The process emissions contain Hydrogen bromide, Hydrogen

chloride, and sulphur dioxide. Hydrogen bromide gas and Hydrogen chloride gas shall be sent to

scrubber in series and converted sodium bromide and sodium chloride salt and sold to actual



user. The other gas expected in the process is Carbon dioxide and Hydrogen which are let out

into atmosphere following a standard operating procedure.

HAZARDOUS WASTE MANAGEMENT

As per CTE- 70101, there will be generation of Process Waste (8.334 MT/Month), Used Oil

(0.001 MT/Month), Gypsum Sludge (10 MT/Month), Discarded Container/ Bags/liner

(40Nos/Month and 200/Month), Briquette Ash (18.334MT/Month)

There will be generation of ETP waste (5 MT/Month), Used Oil (0.060 MT/Month), Process

Organic residue(77.32 MT/Month), Solvent Residue(131.17MT/Month), Process Inorganic

residue(25.85 MT/Month), Spent charcoal and hyflo (38.47 MT/Month), Spent Organic(889.5

MT/Month), Spent Inorganic(145 MT/Month), Spent Solvents (114 MT/Month), Spent Mother

Liquor (1874.63 MT/Month), Discarded Container/ Bags/liner (50Nos/Month and 300/Month

and Briquette Ash (10 MT/Month)

2.0 INTRODUCTION

2.1 THE PROJECT

M/s. Pranshav Health Care will engage for manufacturing of Pharma Intermediates and Active

Pharmaceutical Ingredients at Plot No. 824/16, Near Metco roof, GIDC, Jhagadi-393110,Dist:

Jhagadia, State: Gujarat. The details of products and raw material are given below.

TABLE: 2

LIST OF PRODUCTS AND RAW MATERIAL

EXISTING PRODUCT’S RAW MATERIAL CONSUMPTION QUANTITY (As per CTE

No. 70101)

Sr.

No.

Product Quantity

(MT/MT)

Raw Material Quantity

(MT/MT)

1 Potassium Chloride 500

(either

individual

of total 7

product)

Potassium hydroxide 662.50

Hydrochloric Acid 759.50

Total 1422.00

2 Potassium fluoride Potassium hydroxide 867.50

Hydrofloric Acid 352.00

Total 1219.50

3 Potassium Bromide Potassium hydroxide 420.50

Hydrobromic Acid 709.50

Total 1130.00

4 Potassium sulphate Potassium hydroxide 575.00

Sulphuric Acid 402.00

Total 977.00

5 Calcium sulphate Calcium carbonate 367.50


Total 887.00

6 Magnesium Magnesium oxide 166.50



sulphate Sulphuric Acid 817.00

Total 983.50

7 Sodium Bromide Sodium hydroxide 396.00

Hydrobromic Acid 818.50

Total 1214.50

8 Manganese Sulphate

27% solution

50 Manganese oxide 4.30


Total 50.65

PROPOSED PRODUCT’S RAW MATERIAL CONSUMPTION QUANTITY

Sr.

No.

Product Quantity

(MT/MT)

Raw Material Quantity

(MT/MT)

1 Atorvastatin

calcium

20 1,1-Dimethyl Ethyl -6-(2-

Aminoethyl) 15.39

4-Fluoro -2-Methyl-1-

Oxopropyl 23.52

Cyclohexane 60.00

Iso Propyl Alcohol(IPA) 50.01


Acetonitrile 70.00

Sodium Hydroxide 2.92

Calcium Acetate 3.58

Hyflow 0.24

TOTAL 227.06

2 CH Base 50 Hexa Methyl Di Amine 337.00

Sodium Di Cynamide 517.00

N Butanol 1008.00

Water 965.00

Tri Ethyl Amine 25.00

Sodium Hydroxide Flakes 150.00

Pca Hcl 925.00

Methanol 15.00

TOTAL 3942.00

3 Pentaprazol Sodium

30 2-Chloro 2,3 Dimethoxy

Pyridine 34.69

5-Dithiomethoxymenzimidazole 33.28

NaOH 191.63

Methenol 192.66

DCM 1245.00

TEBA 0.52

Sodium Hypochlorite 147.19

Sodium Thiosulphate Soln. 61.88

MDC 147.19



Acetic Acid 28.59

IPE 486.09

Ethyl Acetate 301.41

Charcoal 0.94

TOTAL 2871.05

4 Tertiary Butyl

Hydroquinone

40 Phosphoric Acid 2.40

Toluene 2.00

Hydroquinone 27.20

Tertiary Butanol (TBA) 18.40

TOTAL 50.00

5 Brinzolamide

4(S)-4-hydroxy-6-sulfonamide

dioxide 52.20

Methane sulfonic anhydride 12.00

Ethyl amine 6.60

Aq.Ammonia 3.99

Con.HCl 2.01

Sodium hydroxide 2.19

Pyridine 3.99

Tetra Hydrofuran(THF) 201.00

Isopropyl alcohol(IPA) 219.00

Sodium bicarbonate 2.01

Carbon 2.01

Hyflow 2.01

TOTAL 509.00

6 Canagliflogin

2-(5-bromo-2-methyl benzul)-5-

(4-flurophenyl)thiophene 42.47

Silyl D-gloconolactone 55.40

Methanol 333.33

Acetone 500.00

Potassium carbonate 6.67

TOTAL 937.86

7 Capecitabine

2,3-Di-O-Acetyl-5-Deoxy-5-

Fluorocytidine 24.94

n-Pentyl Chloroformate 11.40


Sodium Bicarbonate 1.00

Hydrochloric acid 1.46

Methylene Chloride(MDC) 80.00

Methanol 50.00


Activated Carbon 1.00

TOTAL 288.10

8 Cefsulodine Sodium

RS-A-Sulfophenyl Acetic Acid 10.29

(S) –A- Methyl Benzyl Amine 5.77

Acetonitrile 123.00



1-Hydroxy Benzotriazole 6.17

Methane Sulphonyl Chloride 5.23


Methylene Dichloride(MDC) 102.50

Hexane 194.50


7-Amino Cephalosporic Acid 11.96

Boron Trifluride Etherate 37.50

Tert-Butyl Acetate 5.10

Sodium Carbonate 1.00

Hyflow 1.50

Zinc Chloride 0.50

Triethyl Amine 0.50

Ethyl Acetate 20.50

Di Isopropyl Ether(Diipe) 10.00

Pyridine-4-Carboxamide 4.83

Sodium Iodide 4.00

Dimethyl Formamine 5.52

Ethanol 5.00

Sodium Acetate 3.10

Hydrochloride 0.50

Carbon 10.00

TOTAL 613.53

9 Dabigetran

3-[(1-Methyl-2-{[4-(5-oxo-4,5-

dihydro-[1,2,4]oxadiazol-3-yl)-

phenylamino]-methyl)-

1Hbenzoimidazole-5-carbonyl)-

pyridin-2-yl amino]-

propionic acidethyl ester 19.40

P-toluene sulphonic acid 5.00

Acetic acid 4.00

Ethanol 500.00

Hexa chlorofomate 5.60

Acetone 240.00

Potassium Hydroxide 1.92

Hydrochloric acid 0.08

TOTAL 776.00

10 Dapoxetine

Hydrochloride

p-(Dimethylamino)

Benzenepropanol 21.25

1-Fluoronaphthalene 17.30



Dimethyl Sulfoxide(DMSO) 250.00

n-Propanol 200.00

Activated carbon 5.00



TOTAL 508.20

11 Darunavir

(3R,3as,4ar)-

Hexahydrofuro[2,3-B]Furan-3-

Ol 9.51

4-Amino-N-(2R,3S)(3-Amino-

2-Hydroxy-4-Phenyl-Butyl)-N-

Isobutyl Benzenesulfonamide 28.59

Disucinimidyl Carbonate 18.72

Sulphuric Acid 0.20

2-Methyl2-Butanol 1.20

Methylene Chloride(MDC) 60.00

Cyclohexane 48.00


Sodium Chloride 0.20

Sodium Sulphate 0.20



Total 167.57

12 Dexlansoprazole

2-[3-Methyl-4-(2,2,2-Trifluoro-

Ethoxy)-Pyridin-2-

Ylmethanesulfinyl]-1H-

Benzoimidazole

29.41

L (+) Mandelic Acid 12.12


Diethyl Tartarate 20.00

Titanium Isopropoxide 6.00

Triethyl Amine 4.00

Acetone 120.00

Dichloromethane(MDC) 80.40


TOTAL 282.35

13 Diacerein

Aloe Emodine 39.32

Sodium Dichromate Dihydrate 43.36



Tetrahydrofuran(THF) 800.00

Acetone 220.00

Propionic Anhydride 35.20

Conc.HCl 7.28

Toluene 44.00

Acetic Anhydride 20.36

N-Methyl Pyrrolidone 69.97

Methanol 44.00


Celite 4.00



Total 1361.82

14 Dorzolamide HCl

(±)-Trans-5,6-Dihydro-4H-4-

Ethyl Amino-6-

Methylthieno[2,3-B]Thiopyran-

2-Sulfonamide-7,7-Dioxide

59.80


N-Butanol 464.00

Methanol 604.00


Acetone 16.00

(-)Di-Para-Toluoyl-Ltartaric

Acid Monohydrate

20.00





Total 1537.68

15 Dapagliflozin

Intermediate-I 17.40

Intermediate-II 24.93

N-Butyl Lithium In THF 4.73

Toluene 86.67

Acetonitrile 33.33

Methylene Dichloride(MDC) 86.67

Triethyl Tin Hydride 0.33

Trifluro Borate-Etharate 0.67

Total 254.73

16 Esomeprazole

Magnesium

5-Methoxy-2-[[(4-methoxy-3,5-

dimethylpyridin-2-

yl)methyl]thio]-1H-

benzimidazole 48.06

Hydrogen Peroxide 4.97

Vanadium acetyl acetonate 0.14

Sodium hydroxide 2.94

Acetone 224.00

Methanol 90.00

Acetic acid 1.20

Ammonia liquor 0.60

Magnesium Chloride 4.70

Methylenechloride(MDC) 160.00

Toluene 100.00

(S)-(-)-1,1-Bi-2-Naphthol 0.40

TOTAL 637.01

17 Irbesartan

2-Butyl-1,3-

Diazaspiro[4,4]Non-1-Ene-4-

One Hydrochloride 23.17



5-[4'-(Bromomethyl) Biphenyl-

2-Yl]-1-Trityl-1Htetrazole 55.99

Methanolic HCl 6.89

Ethylacetate 100.00

Methanol 133.33

Toluene 100.00

Methylene Methylene 113.33

Isopropanol(IPA) 120.00

Acetone 100.00

30% Sodiumhydroxide Lye 26.07

Sulfuric Acid 5.00


Total 784.43

18 Montelukast

Sodium

2-[2-[3(S)-[3-[2-(7-Chloro-2-

Quinolinyl)-Ethenyl]Phenyl]-3-

Hydroxypropyl]Phenyl-2-

Propanol

26.53

2-[1-(Sulfonyl

Methyl)Cyclopropyl]Acetic

Acid

8.46

Methane Sulfonyl Chloride 6.63


N,N-Diisopropylethylamine 0.13



Acetic Acid 0.26

Toluene 20.00

Acetonitrile 17.33

Methanol 26.67

N-Hexane 34.67


Total 145.63

19

Posaconazole

N-{4-[4-(4-Hydroxyphenyl)-

Piperazin-1-Yl]-Phenyl}-

Carbamic Acid Phenyl Ester 12.06

Formic Acid N'-(2-Benzyloxy-1-

Ethyl-Propyl)-Hydrazide 7.32

(5R-Cis)-5-(2,4-

Difluorophenyl)-5-(1,2,4-

Triazol-1-

Ylmethyl)Tetrahydrofuran-3-

Methanol Tosylate 13.96

Methanol Tosylate 1.24

2,3,4,6,7,8,9,10-Octahydro

Pyrimido[1,2-A]Azepine 1.50



Tetrahydrofuran(THF) 35.00

Formic Acid 50.00

Dimethyl Sulfoxide 90.00

Palladium 1.00



Total 2213.67

20 Quetiapine

Hemifumarate

Dibenzo-(1,4)-Thiazepine-

11(10H)-One 31.48

2-(2-(Piperazin-1-

Yl)Ethoxy)Ethanol 24.13

Fumaric Acid 8.04

Thionyl Chloride 1.00




Toluene 140.00

Ethanol 170.00


Total 382.61

21 Risedronate Sodium

3- Pyridyl Acetic Acid 22.27

3- Pyridyl Acetic Acid 26.64

Diethyl Carbonate 15.00

Caustic Soda Lye 1.00

Sodium Hydroxide Flakes 6.17

Phosphorous Trichloride 0.50

Methane Sulfonic Acid 10.00

Isopropyl Alcohol 116.00


Hyflow 1.00


Total 203.98

22 Telmisartan

1H-Benzimidazole-2npropyl-4-

Methyl-6-(1-Methyl

Benzimidazole-2yl] 23.13

4-Methyl-(Bromomethyl) Bi

Phenyl Carboxylate 23.18

Potassium Hydroxide 4.26

Methyl Iso Butyl Ketone

(MIBK) 83.20



Acetic Acid 29.87

Methanol 60.93

Charcoal Activated Carbon 0.27



Total 225.95

23 Vilazodone HCl

5-{4-[4-(5-Cyano-1H-Indol-3-

Yl)-Butyl]-Piperazin-1-Yl}-

Benzofuran-2-Carboxylicacid

Methyl Ester 48.20

Ammonia 1.04

Methanol 522.00


Sodium Hydroxide 30% 2.44

Isopopyl Alcohol(IPA) 240.00


Total 819.87

24 Levosulpiride

Mono Ethylene Glycol 20.00

2-Methoxy-5-Sulphomyl Methyl

Benzoate 15.00

S-1-Ethyl-5-Aminomethyl

Pyrollidine 7.80

Total 42.80

25

Cilnidipine

Toluene 20.00

2-Methoxy-Ethyl-(3-Nitro

Benzylidine)Acetoacetate 14.00

3-Amino Crotonic Acid

Cinnamyl Ester 10.00

Total 44.00

26 NEBIVOLOL HCL

Benzo Pyran Acetaldehyde 166.67

Benzo Pyran Ethelamine 55.56

Sodium Cyano Borohydried 19.44

THF 3611.11

Methenol 1944.44

Sodium bicarbonate 561.11


6N HCl 277.78

2N HCl 111.94

diethyl Ether 111.11

TOTAL 7970.27

27 Tamsulosin HCl Dimethylformamide 206.86

Ethoxy Phenoxy Ethyl Bromide 21.90

(R)-(-)[2-Aminopropyl]-2-

Methoxy Benzene Sulfonamide 32.95

Methylene Chloride 1366.86

Ammonia Liquor 100.95

Isopropyl Alcohol 978.29

Isopropyl Alcohol (Wash) 495.81

IPA 43.81

HCl 43.81



Water+IPA (7+12.5) (wash) 111.42

IPA 26.67

IPA+HCl (14+13.6) 25.90


TOTAL 3456.38

28 Carbamazepine Methanol 20.28

Iminostilbenecarbonyl Chloride 25.64

Ammonia Liquor 56.15

Toluene 0.80

NaOH 0.57

Acetone 101.30

Hyflo 0.25


Acetone (wash) 28.78

Total 234.03

29 FESOTERODINE Benzyl Amine DPTT 109.08


Cerric Ammonium Nitrate 250.88

NaBH4 15.48

Fumic Acid 29.54

Hydrogen Gas 0.26

Isobutyryl Chloride 6.80

Triethylamine 6.02

TOTAL 532.58

30 Bosentan

Monohydrate

4,6-Dichloro-5-(2-

Methoxyphenoxy)-2,2-

Bipysimidine 14.52

4-Tert-Butylbenzene

Sulfonamide 8.86


Potassium Carbonate 24.12

Sodium Tert Butoxide 19.96

Ethylene Glycol 246.78

TOTAL 317.82

31 VILDAGLIPTIN

DMF 108.00

KSM-II 14.40

KSM-I 15.40

Pottasium Carbonate 62.20

Isopropyl Acetate 100.80

Dichromomethane 425.00

Potassium Hydrogen Sulfate 75.00

NaCl 13.40

Charcoal 1.00

Acetone 264.60

Total 1079.80



32 RIVAROXABAN

(4-4-Aminophenyl)-Morpholin-

3-One 28.22

Glycidyl Phthalimide 32.74

4-

Dimethylaminopyridine(DMAP) 0.14

CDI 80.68

5-Chlorothiophene-2-Cacoxylic

Acid 24.60

Sodium Acetate 29.60

Oxalyl Chloride 29.90

Aq. Methyl Amine 32.54


Total 271.96

33 FEBUXOSTAT

Ksm 30.94

Isobutyl Bromide 23.24

Potassium Carbonate 36.68

Ammonium Hydroxide. Hcl 6.46




Acetone 15.00

Total 130.32

34 AGOMEALTINE

2-(7-Methoxy-1-

Napthyl)Acetonitrile/

Agomelatine 22.47

Hydrogen Gas 0.45

Isopropyl Alcohal HCl 16.63

Sodium Acetate Anhydrous 9.44

Acetic Anhydrous 11.46

TOTAL 60.45

35 Levetiracetam

DCM 775.00

Sodium Sulphate 57.60

TBAB 1.20

S(+)-2 amino butyramide

hydrochloride 23.00

4-Chloro Butyryl Chloride 28.80

KOH 51.60

Activated Charcoal 5.20

Hyflo 60.00


Acetic Acid 14.00

TOTAL 1339.60

36 Methyl Paraben

50 PHBA 50.00

Methanol 14.53

Sodium Bi Carb Soln (5%) 27.78

M/s. JYOTI OM CHEMICAL RESEARCH CENTRE PVT. LTD.

37 Propyl Paraben

38 Ethyl paraben

39 Butyl Paraben

40 Iso Propyl Paraben

41 4- Amino Pyridine 40

42 Dimethyl Ameno

Propiophenone

43 Guaicol

44 Veratrole

45 Diethyl Ethyl

Melonate

M/s. PRANSHAV HEALTH CARE,

M/s. JYOTI OM CHEMICAL RESEARCH CENTRE PVT. LTD.

TOTAL

PHBA

Propanol

Sodium Bi Carb Soln (5%)

TOTAL

PHBA

Ethanol

Sodium Bicarb Soln (5%)

TOTAL

PHBA

Butanol


TOTAL

PHBA

Iso Propanol


TOTAL 101.00

NaOH

Bromine

ISO Nicotinamide

Methanol

Total

Fresh IPA

Recovered IPA

Paraformaldehyde

DMA Hcl

Acetophenone

TOTAL

Sodium carbonate

Fresh Toluene

Recovered Toluene 112.00

Catechol

DMS

HCl 100.00

TOTAL 401.20

NaOH

Fresh Toluene

Recovered Toluene

Catechol

DMS

HCl

TOTAL

Fresh Alcohol

Recovered Alcohol

Sodium


Page 16

92.31

39.37

19.13

8.66

67.17

44.12

35.29

6.47

85.88

37.50

30.00

5.50

73.00

50.00

40.00

11.00

101.00

148.00

140.00

80.00

40.00

408.00

8.00

72.00

36.00

48.00

48.00

212.00

62.40

12.00

112.00

54.80

60.00

100.00

401.20

74.00

6.00

56.00

48.00

80.00

100.00

364.00

10.00

190.00

24.00



DEM 80.00

Ethylchloride 96.00

Fresh Toluene 6.00


TOTAL 480.00

46 3,5 Dinitrobenzoic

Acid


Benzoic Acid 24.00

Nitric Acid 135.00

Caustic lye solution 21.00

Total 225.00

47 P Hydroxy

Acetophenone

Anisol 100.00

Aluminium Chloride 0.56

Acetyl Chloride 80.00

Dichloro Methane + Methyl

Chloride 4.00

Recovered Dichloro Methane +

Methyl Chloride 50.00

TOTAL 234.56

48 Cetylpyridinium

Chloride

Cetyl Chloride 30.68

Fresh Pyridine 1.80

Recovered pyridine 16.76

Fresh Methyl ethyl ketone 12.00

Recovered methyl ethyl ketone 148.00

Fresh Acetone 8.00

Recovered Acetone 72.00

TOTAL 289.24

49 Lauryl Pyridinium

Chloride

Lauryl Chloride 28.88

Fresh Pyridine 2.40

Recovered Pyridine 20.00

Fresh Methyl Ethyl Ketone 16.00

Recovered Methyl Ethyl Ketone 144.00

Fresh Acetone 8.00


TOTAL 291.28

50 Ambroxol

Hydrochloride

Ambraxol Base 36.48

Recovered IPA 380.00

Carbon 0.60

HCl 12.00

IPA washing 20.00

TOTAL 449.08

51 ACEBROPHYLLI

NE

Acefilline 16.00

Ambroxol Base 18.40

Carbon 0.60

DMF washing 20.00

Recovered DMF 380.00



TOTAL 435.00

52 3,5 Dibenzyloxy

Acetophenone

Anisol 28.80

3,5 Dribromo Acetophenone 36.00

Fresh Toluene 2.00


Sulphuric Acid 0.04

TOTAL 82.84

53 Methyl Nicotinate Nicotonic acid 56.00

Methanol 102.84

Sulphuric acid 42.00

Liquor Ammonia 28.00

Fresh Benzene 4.80

Recovered Benzene 45.20

Total 278.84

54 Furoic Acid Caustic soda 160.00

Chlorine gas 100.00

Furfuraldehyde 120.00

HCl 92.00

Total 472.00

55 1 (2,3 Di chloro

Phenyl) Piperazine

Bydroghloride

2,3 Dichloro Aniline 78.80

Recovered 2,3 Dichloro Aniline 24.00

Fresh orthoxylene 4.00

Bis Salt 75.20

Caustic soda lye 30.00

Caustic soda lye 30.00

Fresh toluene 4.00

Recovered toluene 36.00

Fresh Acetone 4.00


HCl 68.80

TOTAL 410.80

56 1 H 1,2, 4 Triazole Formamide 75.00

Fresh Toluene 3.00


Hydrazine Hydrate 37.50

Fresh IPA 6.00

Recovered IPA 54.00

Total 202.50

57 LASAMIDE Dichloro Benzoic acid 62.40

Chloro Sulphonic acid 320.00

Carbon 0.60

Liquor Ammonia 160.00

HCl 220.00

Total 763.00

58 1 (2,4 Di Chloro Meta Di Chloro benzene 40.00



Phenyl) -2 (1

Imidozolyl) Ethanol

Aluminium Chloride 48.00

Fresh Hexane 17.20

Recovered Hexane 154.80

Chloro Acetyl Chloride 40.00

Caystic Lye 28.00

Soda Ash 44.00

Imidazole 28.00

Fresh Toluene 10.00


Sodium borohydrate 12.00

TOTAL 562.00

59 Fingolimod HCL Methylene chloride 611.12

Octylbenzene 22.35

Aluminium chloride 17.21

Bromoacetyl bromide 25.92

NaHCO3+water 262.62

Sodium sulphate 29.37

Methylene chloride (wash) 183.54

Acetone 246.96

Diethylacetamido malonate 43.86

Potassium carbonate 28.10

Acetone (wash) 100.06

Hexane 1794.38

Hexane (wash) 1158.14

Molecular sieve pellet 9.58

MDC 63.91

Triethylsilane 46.70

MDC 126.26

TiCCl4 47.82

Ethyl acetate 525.84

Ethyl acetate (wash) 1428.52

Silica gel 112.83

TOTAL 6885.10

60 2-

MERCAPTOBENZ

IMIDAZOLE

ODPA 30.40

Carbon Disulfide 28.00

Sodium sulphide 2.24

Sodium Hydroxide(47%) 77.60

TOTAL 138.24

61 Bronopol (BP)

Nitro Methane 66.67

Methanol 13.33

Caustic 66.67

Formaldehyde 9.33

Carbon 29.33

Bromine 0.67

TOTAL 35.33



62 2 Mercapto 5

Methoxy

Benzimimidazone

4-Methyl 2-Nitro Anisidine 40.00

Sodium hydro Sulfide 146.40

Carbon disulfide 30.40

Caustic 3.20

Carbon 1.60

Sulfuric acid 0.80

TOTAL 222.40

63 Methyl Acetate

200

Methanol 86.00

Acitic acid 162.00

TOTAL 248.00

64 Ethyl Acetate

Methanol 104.60

Acitic acid 136.40

TOTAL 241.00

2.2 PROJECT PROPONENT

M/s. Pranshav Health Care was incorporated in the year 2013. They are manufacturing

inorganic chemical. Now they want to manufacture Intermediates and Active Pharmaceutical

Ingredients at Plot No. 824/16, Near Metco roof, GIDC, Jhagadi-393110,Dist: Bharuch, State:

Gujarat.

Quality Assurance

We shall adopt a strategic quality control procedure in order to ensure that only reliable

products are delivered from our end. All our products shall be developed through advanced

methodology and innovative techniques. Following strict quality control policies, we shall

develop our products in compliance with international norms.

Ethical business practices and qualitative approach shall provide us with an edge over the

other competitors. Our quality controllers shall conduct tests on the products, right from

the initial stage of procurement of raw material to the final delivery of the consignment.

The name and address of Directors are given in Table 2.

TABLE 3

CONTACT DETAILS OF PARTNERS

Name of Partners Address

1. Mr. Jignesh Sureshbhai Patel 2, Sukhshanti Society-2, Near Gattuchowkdi,

GIDC, Ankleshwar-393002

Mob. No.- 9824206088

2. Mr. Ankit Sureshbhai Patel 2, Sukhshanti Society-2, Near Gattuchowkdi,


Mob. No.- 9824140088

3. Mrs. Manjulaben Sureshbhai

Patel

2, Sukhshanti Society-2, Near Gattuchowkdi,


Mob. No.- 9824140088



2.3 NATURE OF PROJECT

The unit will manufacture Pharma Intermediates and Active Pharmaceutical Ingredients

product.the list of product is given in table 1.

2.4 MARKET FEASIBILITY The proposed project is for proton pump inhibitor (reduction of gastric acid/ antacid), ocular

carbonic anhydrase inhibitor(for open angle glaucoma), anti-diabetic drugs, chemotherapeutic

drug, antibiotic (3rd

generation cephalosporin), anticoagulants, for treatment of HIV

INFECTION, anti-hypertensive drugs, leukotriene antagonist, anti-fungal drugs, etc. product .

Demand & supply gap is huge in Indian and export market.

As the product of Pranshav Health Care has good demand in under developing nation and

developed country . They have more exporting possibilities throughout world like Bangladesh,

Myanmar, Sri Lanka and some African countries, European countries.

As well Pranshav health care has good market in local region an planned to distribute throughout

Gujarat. As the products are very competitive in prize and high quality when compare to other

product it has good demand in Gujarat.

2.5 EMPLOYMENT GENERATION DUE TO THE PROJECT

The details are given below.

TABLE: 4

DETAILS OF MANPOWER

Phase of Project Type of Labor No. of Worker

During construction Contractual 50

During commissioning Contractual 20

During operations Managerial 3

Skilled 10

Un-skilled 50

Note: There will be no change in No. of manpower due to Proposed Expansion.

3.0 PROJECT DESCRIPTION

3.1 TYPE OF PROJECT The proposed project is not including any interlinked and interdependent projects.

3.2 PROJECT LOCATION The proposed project site is located at Plot No.A-1/ 4701 & 2 02/B, GIDC Industrial Estate,

Ankleshwar, Dist. Bharuch in the state of Gujarat. It is approximately 20 km distance from



district head quarter Bharuch. The approximate geographical positioning of the project site is at

Latitude: 21°37’32.00”N, Longitude 73° 8’17.00”E. The location of the project site can be

identified from the location map shown in Figure -2.

The salient features of the location of the project site are presented in below Table.3.

TABLE: 5

SALIENT FEATURES OF THE PROJECT SITE

Particulars Details

Village Dadheda about 1.35 KM

Taluka/ Tehsil Jhagadiya about 11 KM

District Bharuch about 20 KM

Approx. Geographical positioning Latitude 21°37’32.00”N

Longitude 73° 8’17.00”E

Nearest City Bharuch about 20 KM

Nearest Town Ankleshwar about 13KM

Nearest Highway National Highway No. 8 about 13 KM

Nearest State highway National Highway No. 8

Nearest Railway line/ Railway

station

Ankleshwar Railway Station about 14 KM

Nearest Airport/ Airbase Vadodara about 94 KM



FIGURE 1

LOCATION OF THE PROJECT SITE

Ankleshwar Industrial area

Panoli Industrial area

Jhagadia industrial area

Priaman CETP

Canal

Piraman to Katiyajal Effluent

Pipe

Jhagadia to Piraman CETP

Panoli to Piraman CETP

Diffuser Point

PROJECT SITE



FIGURE: 2

AERIAL VIEW OF THE 5 KM RADIAL PERIPHERY FROM THE PROJECT SITE

3.3 SITE SELECTION

This is expansion project. So the proponent did not consider any other alternative site for

proposed expansion. The existing plot has sufficient area for carrying out expansion.

3.4 NEIGHBOURING INDUSTRIES

The industry is located in an area, which is already industrialized. The industries in the vicinity

of the proposed project are given in the table 4:

TABLE 6

NEARBY INDUSTRIES IN THE VICINITY

Name of Industry Direction with respect

to project site

Address

Open land of GIDC East side of company

Lucid Colloids Ltd North side of company Plot No.757/1,Road No.1

GIDC,Jhagadia Indl, Estate

Jhagadia-393110



Metco Roof Pvt Ltd South side of company Plot No:824/20&21 GIDC,

Jhagadia, Ankleshwar, Gujarat

393110

Yashdeep Chemical Pvt Ltd West side of company Plot No:676,jhagadia industrial

area,g.i.d.c.,jhagadia,jhagadia,bharu

ch-393110,

3.5 SIZE OF PROJECT

The expected cost of proposed project is Rs. 505 lacs.

New Plant and machinery installations will also have to be acquired and installed.

Environment Protection and safety systems have also been considered in planning the Cost

Projection. Green belt development, provision of fire extinguishers etc. are also calculated. The

following table shows the break-up of the proposed project cost.

TABLE 7

CAPITAL COST OF PROJECTION

Sr.

No.

Purpose Total (Rs. In Lacs)

1. Land 55

2. Building 150

3. Plant and Machinery 200

4. Q.A. Lab set up 50

5. Env. Protection & Safety

a) Effluent treatment Plant 25

b) Air pollution control & Hazardous

waste management

10

c) Safety Equipment (PPE, fire

extinguishers, Ventilation, etc.)

10

d) Green belt development 5

Total 505

3.6 PROCESS TECHNOLOGY

Process details like process description for each grade of products are covered separately in

Annexure-VI of Form-I.

3.7 RAW-MATERIALS

Details of raw-material consumption are covered in Annexure-V of Form-I.

3.8 RESOURCE OPTIMIZATION/RECYCLING AND REUSE

3.8.1 SOLVENT RECOVERY SYSTEM



PROCESS DESCRIPTION

A solvent recovery system comprises of two stage heat exchangers. Cooling tower water

is circulated in primary heat exchanger and in secondary heat exchanger chilled water

circulation is done. The uncondensed solvent after the secondary heat exchanger will be

diverted to water scrubber the traces of solvent will get dissolved in water. On getting

saturation, the solvent mix water will be subjected for recovery of solvent (if feasible)

and/or water will be diverted to ETP plant for further treatment the process will ensure

no VOC emission from solvent recovery system.

FIGURE: 3

SOLVENT RECOVERY SYSTEM

Reactor

Primary

Condenser

Cooling Tower Line

Secondary

Condenser

Chilled Water

Circulation Spray

Water Tank

Receiver



3.9 RESOURCE REQUIREMENTS

3.9.1 LAND The plot has been purchased by M/s. Pranshav Health Care from GIDC. The total plot area of the

unit is Area- 5700Sq.Mtr.

3.9.2 BUILDING The new building will be constructed.

TABLE: 8

APPROXIMATE REQUIREMENT OF CONSTRUCTION MATERIALS

Material Qty. Source

Cement 10000 bag From local supply

Sand 3000 tonne

Gravel 150 tonne

Steel 2000 tonne

3.9.3 POWER AND FUEL The unit’s power and fuel requirement is provided in Table 6. There will not be any increase in

fuel consumption.

TABLE 9

POWER AND FUEL REQUIREMENT

Sr.

No.

Particulars Requirement Remark

Electricity

1 Electricity 125 KVA DGVCL

Fuel

2 Bio-Coal 300 tonne/month From local supply

3.9.4 WATER

The category wise bifurcation of the water requirement is given in Table no 7. The source of

water will be from GIDC water supply scheme. There will be no change in Proposed Water

consumption due to Proposed Expansion.

TABLE 10

DETAILS OF WATER CONSUMPTION

Sr.No. Category As per CTE No. 70101

Water Consumption

(KL/Day)

For Proposed project

Water Consumption (KL/Day)

1. Domestic 2.5 10

2. Industrial



Processing 3.0 102(fresh) +63(Recycle)

Washing 2.0 40(Recycle)

Boiler 0.5 35

Cooling 00 5(fresh)+25(recycle)

Gardening 2.0 5(recycle)

Total(Industrial) 7.5 132 (fresh)+133(recycle)

Total

(Industrial + Domestic)

10.0 142 (fresh)+133(recycle)

3.9.5 MANPOWER

The manpower required for the project as well as during the construction/ commissioning

activities will be employed from the local area. The details are provided in Table 8.

TABLE 11

DETAILS OF MAN POWER REQUIREMENT

Sr. No. Category Total Manpower

1. Managerial 4

2. Technical 7

3. Administrative 7

4. Skilled workers 15

5. Unskilled workers 50

Total: 83

3.10 MITIGATION MEASURES & EMP

Based on overall manufacturing & operation activities, the mitigation measures have been

proposed by the company for the control of the anticipated pollution load.

3.10.1 WASTEWATER MANAGEMENT

The category-wise bifurcation of the anticipated wastewater generation details is given in Table

9. There will be no change in Proposed Wastewater generation due to Proposed Expansion.

TABLE 12

DETAILS OF WASTEWATER GENERATION



Note:

*Zero

Discha

rge

Unit.

Domestic waste disposed off through soak pit/ septic tank.

Category As per CTE No. 70101

Waste Water

Generation (KL/Day)

For Proposed Project

Waste Water

Generation (KL/Day)

Domestic: 1.5 7

Industrial:

Process 00 155

Boiler 00 10

Cooling 00 5

Washing 00 3

Other 00 0

Total (Industrial) 00* 173

Total

(Domestic + Industrial)

1.5 180



FIGURE-4

WATER BALANCE DIAGRAM

Domestic

10

Soak Pit

7

Total water consumption

142(fresh) +133(recycle)

Process

102(fresh)

+63(Recycle)

Boiler

20

Cooling

5(fresh)+

25(recycle)

Gardening

5(recycle)

Effluent from

Process

155

Boiler blow

down

5

Cooling blow

down

3

Effluent Treatment Plant

173

RO Plant

173

RO Reject

70

RO Permeate

103

Evaporator

45

Condensate

30

Reject

10

To NCTL

25

Loss

10

Loss

15

Loss

25

• All quantity is in KL/Day

Washing

40

(recycle)

Loss

30

Loss

5



3.10.1.2 WASTEWATER CHARACTERISTICS

Industrial wastewater will be generated from process, cooling tower and boiler. The expected

characteristics of industrial wastewater are provided in Table 10.

TABLE 13

WASTE WATER CHARACTERISTICS

Sr.

No. Parameters Units

Standards

prescribed

Inlet ETP

RO Inlet

Dicharge

1 pH -- 6.5 to 8.5 6.5 – 8.5 6.5-8.5 6.5-8.5

2 Total Suspended

Solids mg/l 100

300 – 400 100-120 80-100

3 Total Dissolved

Solids mg/l ---

3500-6000 3500-6000 ---

4 B.O.D.(3 days at

27°C) mg/l 100

1200-1500 200-250 80-100

5 C.O.D. mg/l 250 5000-6000 1000-2100 150-250

3.10.1.3 WASTEWATER TREATMENT & DISPOSAL

Effluent coming from various streams is passed through Oil & Grease separator and then

collected in existing collection tank no.1. Then that effluent transfer to new ETP equalization

tank.

After that effluent transfer to neutralization tank where pH is maintained by dosing of lime /

alum. After ensuring pH, effluent is transferred to the primary clarifier tank.

Sludge settled at bottom of the clarifier is transferred to the sludge drying beds.

Over flow of primary clarifier effluent will goes in Aeration Tank, where continue air is supplied

by means of diffused Aeration System for biodegradation of organic matters. Nutrients are added

as per requirement. The overflow is goes to Secondary Clarifier's, where settlement of biomass

takes place. Some biomass is recycled in the aeration tank by circulation pump and partly

biomass wasted in to sludge drying bed & sludge from decanter is stored in Hazardous Waste

Storage Area, having impervious layer and leachate collection system. Finally, stored hazardous

waste disposed off to government approved land filling site.

Over flow of secondary clarifier sent to intermediate tanks where sodium hypo chloride added.

Then effluent is passed through Activated carbon filter.

After filtration waste is transferred to final treated tank. Treated effluent from the final collection

tank is transferred to RO plant. RO permeate is reuse and rejected is sent to evaporator. The

evaporate permeate is used in cooling tower and gardening purpose.



PARTICULARS OF EFFLUENT TREATMENT PLANT

Sr.

No.

Description Size (L*W*D) Nos. Capacity

1 Equalization tank 4.5*6*4 1 108 m3

2 Neutralization tank 2.3*2.3*3 1 16 m3

3 Lime soln preparation tank 300 lit 1 0.3m3

4 Alum soln preparation tank 200 lit 1 0.2m3

5 Primary clarifier 2.5 M dia*2.5 1 51.3 m3

6 Aeration tank 7*6*4 1 168m3

7 Secondary clarifier 2.5 M dia*2.5 1 51.3 m3

8 Filter Foundation 6*3 1 18 m2

9 Storage tank 7*5*5 1 35m3

10 RO Shed 7*9 1 63m2

11 RO rejection tank 4.2*4.3*4 1 72.24m3

12 RO permeate tank 5.1*5.1*4 1 104.04m3

13 Sludge sump 2*2*3 1 12m3

14 Sludge drying bed 2*1.5*3 1 9m3

15 Evaporator 45m3

16 Condensate 30m3

17 Operator room 3*6 1 18m2

18 Hazardous Waste area 3*4 1 12m2



FIGURE -5

FLOW DIAGRAM OF ETP

Primary

Clarifier

Secondary

Clarifier

Carbon Filter

column

Evaporator

RO

Column

RO Reject

RO

Permeate

Condensate Reject

Equalization

Tank

Neutralization

tank

Aeration Tank

Sludge Drying Bed TO TSDF

Sludge

Sludge

S

l

u

d

g

e

Activated Sludge

Storage

Tank

Effluent

Reuse



3.10.2 GASEOUS EMISSIONS & CONTROL

There will be flue gas emission from One Boiler. Biocoal will use as fuel. The air pollution

control measures are covered in below table 12.

TABLE 14

DETAILS OF FLUE GAS EMISSIONS

Sr.

No.

Stack

Attached

To

Stack

Height

Fuel

Consumptio

n

Air

Pollution

Control

System

Type

of

Emission

Permissible

Limit

As per CTE-70101

1.

IBR

Boiler

( 2TPH)

11 m

Wood:- 700

Kg/Day Or

Baggase:-

700Kg/Day

Multi

Cyclone +

Bag Filter

PM

SO2

NOx

150mg/NM3

100 PPM

50 PPM

For Proposed Project

1.

IBR

Boiler

( 2TPH)

11 m

Wood:- 700

Kg/Day Or

Baggase:-

700Kg/Day

Multi

Cyclone +

Bag Filter

PM

SO2

NOx

150mg/NM3

100 PPM

50 PPM

3.10.2.2 PROCESS EMISSIONS

The process emissions contain Hydrogen bromide, Hydrogen chloride, Carbon dioxide, sulphur

dioxide and Hydrogen.

Hydrogen bromide gas and Hydrogen chloride gas shall be sent to scrubber in series and dilute

sodium bromide and sodium chloride sent to recyclers/recovery units. The other gas expected in

the process is Carbon dioxide and Hydrogen which are let out into atmosphere following a

standard operating procedure.

TABLE 15

DETAILS OF PROCESS GAS EMISSIONS

Sr.

No.

Stack

Attached

To

Stack

Height

(m)

Stack

Diameter

(m)

Air Pollution

Control System

Type of

Emission

Permissible

Limit

1.

Reactor

Vessel

25 0.5 Water

Scrubber+Causti

c Scrubber

HBr

SO2

HCl

20 mg/Nm3

40 mg/Nm3

20 mg/Nm3



3.10.3 HAZARDOUS/ NON-HAZARDOUS WASTE MANAGEMENT

The following type of hazardous waste will be generated from the operational activities. All the

waste will be stored separately in a designated storage area.

TABLE 16

DETAILS OF HAZARDOUS WASTE

Sr.

No.

Name of

Waste

Categ

ory

Quantity

As per

CTE No.

70101

Quantity

for EC

Treatment & Disposal

1 Process

Organic

residue

28.1 0 77.32 Collection, storage for Onsite

Distillation

OR by

authorized other vendor OR Sale to

authorized recycler

2 Solvent

Residue

28.1 0 131.17 Collection, storage, transportation &

disposal by incineration at CHWI or

send for co�processing in cement

industries

3 Process

Inorganic

Residue

28.1 0 25.85 Sent to TSDF

4 Spent

charcoal and

hyflo



send for co� processing in cement

industries

5 Spent

Organic



send for co� processing in cement

industries

6 Spent

Inorganic

28.2 0 145.00

Sent to TSDF

7 Spent

Solvents



send for co�processing in cement

industries

8 ETP Sludge 34.3 0 5 Collection, storage, transportation &

disposal to TSDF

9 Discarded

Container/

33.3 40 Nos.

200Nos.

50 Nos.

300 Nos.

After detoxification sent

to Authorized agencies

2. Reactor

Vessel

25 0.5 ---- CO2

H2O

� There is no process gas emission from Existing Product.



Sr.

No.

Name of

Waste

Categ

ory

Quantity

As per

CTE No.

70101

Quantity

for EC

Treatment & Disposal

Bags/liner

10 Used Oil 5.1 0.012 MT 1KL/Mon

th

After detoxification sent

to Authorized agencies

11 Spent Mother

Liquor

28. 4 0 1874.63 Collection, storage, onsite treatment in

MEE Dryer & incineration OR

transportation & disposal by

incineration at CHWI or send

for co� processing in cement industries

12 Process

Waste

34.3 8.334 0 Sent to TSDF site of M/s. BEIL,

Ankleshwar

13 Gypsum

Sludge

-- 10 0 Sent to TSDF site of M/s. BEIL,

Ankleshwar OR Brick manufacturer

14 Briquette

Ash

-- 18.334 10 Sold to Brick

manufactures

3.10.4 NOISE CONTROL & ODOUR

Ear plugs will be provided to the operating personnel in boiler room. Low noise generating

equipments will be selected. Adequate engineering controls will be implemented to avoid noise

pollution.

The following steps will be taken for odour control.

• Raw-material feeding will be carried out by pumps and in close loop system.

• All reactions will be taken in closed reactor system.

• Roof top ventilation will be provided in the entire plant area.

• Regular monitoring will be done of piping and fittings for checking of any leakages.

3.10.5 STORAGE, HANDLING AND TRANSPORT OF HAZARDOUS

CHEMICALS

The storage and mode of transport of chemicals will be done as per detailed MSDS and chemical

hazards guide (NIOSH) for the hazardous chemicals.

Few chemical to be used in the proposed activities are listed as ‘Hazardous Chemicals’ as per the

Schedule-1 of the MSIHC Rules, as amended in 2000.

3.10.6 HEALTH AND SAFETY MEASURES

Few chemical to be used in the proposed activities are listed as ‘Hazardous Chemicals’ as per the

Schedule-1 of the MSIHC Rules, as amended in 2000.

Physical hazards may manifest as fires, explosions, excessive temperatures, or the release of

large volumes of gas or toxic or flammable gases or vapors. According to Schedule 2 & 3 of

MSIHC Rules.



4.0 SITE ANALYSIS

4.1 CONNECTIVITY Jhagadia industrial estate is mega industrial estate located in close proximity to GIDC,

Ankleshwar. National highway 8 passes through the district connecting it with Ahmadabad (180

km) and Mumbai (370 km). The Jhagadia is located at 30 km distance from Bharuch Railway

station. The nearest domestic airport Vadodara is at an approx distance 100 km from Jhagadia.

The nearest International airport Ahmadabad is at a distance 225 km.

The town is known for its industrial township called GIDC (Gujarat Industrial Development

Corporation). Ankleshwar has an office of the ONGC (Oil and Natural Gas Corporation

Limited). GIDC is organizing Trade fare and Industrial expo occasionally to attract large number

of industries all over from India. It also helps to get customer on large basis.

Bharuch is connected by Indian National Highway 8 (Mumbai to New Delhi) and by the

Western Railway Division of Indian Railways. The railway division also runs the broad

gauge train services to Rajpipla. The 133 year-old Golden Bridge connects Ankleshwar to

Bharuch across the Narmada on the station front while a new bridge connects the highway, the

other bridge on the highway is now ready to use.

Healthcare

Hospitals include are the

• Bharuch Welfare Hospital

• Sai Shraddha Multispeciality Hospita

• Global Bharuch Hospital

• Civil Hospital

• SEWA Rural

4.2 LAND USE AND LAND OWNERSHIP

The proposed project site is located at Plot No. 824/16, Near Metco roof, GIDC, Jhagadi-

393110,Dist: Bharuch, State: Gujarat. The total plot area of the unit is 5700Sq. M. Land

ownership is with project proponents. The geographical location is Latitude: 21°37’32.00”N,

Longitude 73° 8’17.00”E

4.3 EXISTING LAND USE

The proposed project site is located at Plot No. 824/16, Near Metco roof, GIDC, Jhagadi-

393110,Dist: Bharuch, State: Gujarat.The plot is notified by GIDC for industrial purpose.

4.4 EXISTING INFRASTRUCTURE The project is located in a well-developed zone, which have all essential facilities such as well-

connected road network with ease of transportation, arrangement for supply of water and power

to industries, effluent disposal facilities etc.

4.5 SOIL CLASSIFICATION



The soils of the district are derived from the Deccan trap which is main rock formation of the

district. The soil of the district can be classified as light, medium and heavy according to depth,

texture and location. There is sandy loam to loamy in texture, brownish black in color.

4.6 CLIMATE DATA As per gathered meteorological data, the maximum temperature is 43°C, where as the

minimum temperature is 14.8°C. The relative humidity levels varied from 13% to 86%. The

maximum and minimum as well as relative humidity for a period of March, 2014 to May, 2014

are presented in Table 15.

TABLE 17

DETAILS OF MICRO METEOROLOGICAL DATA

(Data from Indian Meteorological Department, Ahmadabad)

Based on the above metrological data, wind rose has been prepared for the summer season

period from March 2014 to May 2014. As per the metrological data, it shows that the average

wind speed in March, April, and May 2014 is 2.76 m/s with wind direction blowing to NE.

The wind rose prepared from same data is shown at Figure 6.

FIGURE 7

WIND ROSE DIAGARM FOR PERIOD (MARCH TO MAY, 2014)

Month Temperature(oc) Humidity (%) Rain fall

(mm)

Maximum Minimum Maximum Minimum Maximum

MARCH 2014 38.2 14.8 84 13 0

APRIL 2014 43 22.8 86 14 0

MAY 2014 42.4 27.2 83 15 0.8



4.7 SOCIAL INFRASTRUCTURE

There are 41 villages in Jhagadia Taluka. Population density and sex ratio of Jhagadia Taluka

was reported 212 persons/sq.km. and 937 females per 1000 males respectively in 2001 census

report. Total literacy of Jhagadia Taluka was found 65.92 %.The basic amenities like primary

and secondary education schools, community health workers, primary health sub centre, private

practitioners, primary health centre, maternity and child welfare, dispensaries, T.B clinic, family

welfare centre, hospital, drinking water, transportation facilities, electricity , telephone etc. are

available.

5.0 PLANNING BRIEF

5.1 PLANNING CONCEPT

With increasing demand for land for chemical industries, Government of Gujarat acquires about

1800 hector of land in Jhagadia Taluka. This is Mega industrial estate and only large scale

industries are allotted industrial plots. Jhagadia has been identified as a thrust area for large scale

industrial development by the Government of Gujarat. Jhagadia industrial estate is in close

proximity to State Highway No. 6. National highway 8 passes through the district connecting it

with Ahmedabad (182 km) and Mumbai (362 km).

The main objective of establishment of GIDC at a strategic location of Jhagadia is to make

available the common infrastructure facilities at the least cost. This land is developed and various

common infrastructure facilities like roads, street lighting, electric supply, water supply, effluent

disposal facility etc is established to cater the various kind of industries. The change in concept

of the development of an estate from purely an industrial estate to an industrial park of an

international standard and to attract industries in this mega estate is as per the policy of the

central Government. Already giant industries like United Phosphorus Ltd, Vardhman Acrylics

Ltd, Pepsico Ltd, DCM groups and Birla’s textile unit and others have established their facilities.

5.2 POPULATION PROJECTION

As per provisional reports of Census India, Population of Bharuch District in 2011 is 1,551,019.

Population of male and female are 805,707 and 713,676 respectively. The sex ratio of Bharuch

city is 920 females per 1000 males.

In education section, total literates in Vadodara District are 2,893,080 of which 1,614,087 are

males while 1,278,993 are females. Average literacy rate of Vadodara district is 78.92%.

5.3 LAND USE PLANNING

The proposed project is on a GIDC land.

5.4 ASSESSMENT OF INFRASTRUCTURE DEMAND

The M/s. Pranshav Health Care shall get water from GIDC water supply scheme. So there will be

no additional stress on ground water resources and there will be no adverse effect on the ground

water resources available in the nearby area.



The unit has proposed 250 KVA connected load form DGVCL. The transportation facilities will

also expect to improve due to increase in the movement of workers and raw material and finished

products.

5.5 AMENITIES/FACILITIES

The available basic amenities are as under:

(A) Education Facilities: All the villages have a minimum of one primary school.

(B) Medical Facilities: All the surrounding villages have medical facilities.

(C) Drinking water Facilities & Power Supply: All the villages have potable water supply and in 100% area the drinking water is supplied

through taps, wells and tube wells. All the villages have power supply facilities in the study

region.

(D) Post, Telegraph & Telephone facilities The information collected clearly indicates that the infrastructural facilities are provided by

respective government agencies for the development of this area. For communication purpose,

post office and phones are available in most of the villages.

(E) Transport Facilities: Bus services are available in all the villages of the study region within 5 km area and are the

most preferable mode of transport in the region. Auto-rickshaw is also used as transport facility.

Villages are connected with paved roads. All the surrounding area is covered with 108

emergency facilities.

6.0 PROPOSED INFRASTRUCTURE

6.1 PROCESSING AREA

The process area will cover plant area like GMP plant, plant-1,2,3,etc, ETP and utilities. The

process area covered by the unit at ground level will be 2085sq.m.

6.2 NON PROCESSING AREA The non process area will cover Electrical panel room, CCOE area, Warehouse-solid & liquid,

TOC Room, canteen, water tanks-all, Cold Room, Security cabin & OHC Room, HT Yard and

surrounding area-utility & main, Admin Block, Scrap yard, open area near H2 plant, BHP Gully

and all roads and passages, contractor sheds, Parking area etc. The non process area covered by

unit at ground level will be around 1965 sq. m.

6.3 GREEN BELT

Out of the total land area of 5700sq. m. approximately 30%will be utilized for green belt

development. The proposed greenbelt area is 1350 sq. m.

6.4 SOCIAL INFRASTRUCTURE



The availability of basic amenities is covered as under:

(A) Training & Education: All the employees will be trained and educated periodically about the

hazardous nature of chemicals used in the process. Also, training for firefighting, work permit

system, first aid, safe handling of hazardous chemicals and integrating safety, in all activities.

(B) Medical facility: Pre-employment medical checkup at the time of employment. In order to safe

guard the health of the employees, all the employees undergo periodic health checkup.

(C) Drinking water: There will be provision of Aqua Guard/R.O. at different places to provide

purified water for drinking purpose.

(D) Transportation: The unit will provide basic transportation facility for workers.

(E) Telegraph & Post: There will be provision of telephone, fax & internet facility.

(F) Power supply: There will be total connected load of 7446000 KWH from DGVCL.

6.5 CONNECTIVITY

Ankleshwar estate is well connected by rail and road to rest of country.

6.6 DRINKING WATER MANAGEMENT

Average daily water consumption of unit will be 10 KL/Day for domestic purpose. The entire

water requirement will be meeting through GIDC water supply system.

6.7 SEWAGE SYSTEM

The sewage will be treated in soak pit.

6.8 INDUSTRIAL WASTE MANAGEMENT

The hazardous waste like ETP waste, Spent Oil and Discarded containers will be generated from

the proposed activity .There will be no change in Hazardous waste generation due to Proposed

Expansion. The hazardous waste management and disposal is shown in table 14.

6.9 SOLID WASTE MANAGEMENT

The record of hazardous and non Hazardous waste solid waste like Personal Protective

Equipments and Broken Glassware etc. will be mentioned.

6.10 POWER REQUIREMENT & SUPPLY

The unit will use total 100KVA electricity connected load from DGVCL.

7.0 REHABILITATION AND RESETTLEMENT(R &R) PLAN The proposed project is located in Plot No. 824/16, Near Metco roof, GIDC, Jhagadi-393110,

Dist: Bharuch, State: Gujarat.. There will be no any human settlement affected by proposed

project.



8.0 PROJECT SCHEDULE & COST ESTIMATES

8.1 PROJECT IMPLEMENTATION SCHEDULE

TABLE: 18

PROJECT IMPLEMENTATION SCHEDULE

Project implementation schedule after getting NOC from GPCB

Sr.

No.

Activity Required Period

1. Civil work Immediately after getting NOC

2. Procurement of

machinery

1 month after getting NOC

3. Eraction & installation

of machinery

Immediately after competition of activity no.2

4. Trial of machinery &

equipment

Within 1 months after competition of activity no.3

5. Commercial activity 1 months after competition of activity no.4

8.2 ESTIMATED PROJECT COST

TABLE: 19

CAPITAL COST PROJECTION

9.0 ANALYSIS OF PROPOSAL

Sr.

No.

Purpose Total (Rs. In Lacs)

1. Land 55

2. Building 150

3. Plant and Machinery 200

4. Q.A. Lab set up 50

5. Env. Protection & Safety

a) Effluent treatment Plant 25

b) Air pollution control & Hazardous

waste management

10

c) Safety Equipment (PPE, fire

extinguishers, Ventilation, etc.)

10

d) Green belt development 5

Total 505



All the manpower is utilized from local region around Ankleshwar. Company shall also try to

provide indirect employment opportunities by availing local contract services during

transportation during operational phase.

The company intends to donate 20% of the profit to agencies like NGOs or social welfare

societies for projects carried out in nearby village for their welfare and upliftment.

Documents

M/s. PRANSHAV HEALTH CARE - Welcome to Environment€¦ · FOR TREATMENT OF HIV INFECTION 17 Darunavir ANTHRAQUINONE (FOR TREATMENT OF OSTEOARTHRITIS) 18 Diacerein ANTI-HYPERTENSIVE