MICRO First Script

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    IN THE NAME OF ALLAH

    Hi mates, Zezo + Yanal + A3raj talking ,

    We are going to study microbiology and we will know the reason

    of studying it and why it will be beneficial to dental students, and

    why we need to study microbes, we will study the first organisms

    on earth and how these micro organisms appear on the earth for

    the first time, and we will study diseases knowledge and micro

    organisms that micro biology concerned of.

    I know that you had taking some of it in school but its one

    important material and you will take it even wider

    Microbiology ???? 0 . 0

    Micro .. biology , it is the biology of tiny creators , tiny organisms

    that include fungi, bacteria, protozoa, Cyanc bacteria and

    Archaeac

    So, biology is the study of living organisms and micro is the study

    of tiny living organisms that no one can see them by his naked

    eyes ( john cena :P ) , he needs microscopes to see these

    organisms .. bla bla bla .. bl mo5tasar micro organisms can be

    found everywhere ( s77a Dr )

    So we will get more knowledge about these different types of

    these micro organisms

    Divisions of micro organisms, there is a cellular pathologically

    infection agents and there is bacteria which is cellular, and one

    important thing in cellular we have prokaryotic ( bacteria )

    eukaryotic ( our cells , plant cells and animal cells ) .. ( s77aaaaa )

    Viruses, we just have to know that they are a cellular organisms.

    Germs : micro organisms that carries diseases, they are carrying

    them all the time , germs and viruses are infection agents they

    going to harm us, these organisms that cause us harm and

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    disease we can call them pathogenic agent or pathogenic micro

    organisms, and the one that doesnt cause diseases we can call

    them non pathogenic.

    Pathogenic organisms ( agents ) they have special weapons andcharacteristics that going to cause us diseases, and non

    pathogenic organisms will not cause us any diseases, we can eat,

    drink, and sniff them without getting infected with any kind of

    disease, while others may give us severe infections depending on

    the disease factor that they carry

    Why we study micro organisms ??

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    3- Taking a place on our skin to prevent pathogenic micro

    organisms from taking this place and get us infected.

    4- Fight with pathogenic micro organisms on the nutrients not

    allowing them to have any of it, so without the nutrients theywill die.

    We should mention that sometimes these pathogenic

    organisms are part of Normal flora and we can call them

    opportunistic organism that wait for the opportunity to get

    us infection, but the other parts of Norma flora are stronger

    than these organisms so they prevent them from getting us

    infections, and one thing to be mentioned, never ever use

    bacterial killer soap because you will kill all the Norma flora

    part, giving the opportunity for these organisms to attack

    our body, just use the normal soap ( ,

    ) LOOL :D

    Micro organisms are very important creators of this planet.

    So why they are important to us ?? why we need micro

    organisms ??

    1- They live around us

    2- We can get anti-biotic and treatment from them

    3- Helping us by coexisting with us in different ways

    4- Some of them produce many things such as penicillin that

    was discovered by Alexandar Fliming in 1928, and

    penicillin was discovered by coincidence where he plantbacteria on a plate and provide food and reasons to live

    and left it for 24 hour, and he came back and notice that

    there is something above the plate, it was like a cotton, he

    took them, studied and identified them, and he found that

    it was not bacteria, it was fungi that produce chemical

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    materials that inhabit the growing of bacteria, and he

    called the fungi Penicillium, and what it produce is

    Penicillin, since that time they use it as a fighter for

    bacterial infectors specially with Tai brown positive

    bacteria, this is one of the benefits of micro biology

    5- 50% of anti-biotic in the pharmacy comes from

    Strebtomioces and the others comes from fungi and the

    other bacteria

    Another thing to be mentioned that we should start finding

    new organisms to give us anti-biotic because some

    pathogenic organisms at this time they dont be affected by

    their anti-biotic like Stafo cocus arius, this bacteria is veryimportant for dental student because it can cause infection

    beneath teeth and even it can cause abscess in gum and it

    can be killer, doctors used to treat it with Hepsilline, but

    sometimes it doesnt work, so we need to find new micro

    organisms in order to fight such kind of these bacteria that

    want to be treated with the anti-biotic in the next few years

    6- Some bacteria help us be decomposing died materials

    and give us nutrients can be used

    for planting things, and for growing things, so they provide

    us with an important stuff and even there is the garbage

    decomposing this is very important cause like in Brazil they

    use bacteria special kinds of them and fungi in order to just

    decompose the garbage and even make the natural gas

    from it and a very big industry branch in Brazil is formed

    cause of the garbage decomposing and they can through it

    produce huge amounts of energy and reduce the garbageamount which can cause a big series

    Microbiology has got many branches

    There is the basic microbiology genetic microbiology which is

    (ta5a9o9 eldactoora ) and (shahadetha beldoctora kanat fe hada

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    elmajal) and there is basic microbiology medical microbiology

    diagnostic microbiology basic oral microbiology ((for dental

    students )) food microbiology and industrial microbiology and

    many others different branches

    They use multiuse bacteria in order to make different things like

    the food microbiology that we use it in making different kind of

    food like bacteria in yogurt and in making alcohol and in fertilizing

    things these we can use some kind of microbiology in making and

    preparing them

    Even some bacteria and micro organisms live by eating t7aleb

    and another use for micro organism is in genetic engineering

    where they can use them to produce different kinds of treatmentlike insulin which is used for people who have Diabetic and they

    use some bacteria that produce whatever you plant in it and they

    let it produce the insulin and then separate it and put it in

    packages and give it to Diabetic patients

    Even we can use microorganisms in air cycles such as nitrogen

    cycle where if you have a land and u used to plant it and then u

    stopped and u didnt give it water then u should give the soil

    some nitrogen by using urea which is full of n2 and here comes

    the rule of the microorganisms in order to stabilizing the nitrogen

    in the because that these microorganisms helps in recycling the

    nitrogen and as we mentioned it helps in making it more stable

    Bacteria also helps in digestion of food where we have a kind of

    bacteria in the small intestine that produce vitamin k which is

    important for the digestion of food ,and it also help in the

    digestion by it self

    The use of bacteria in the food industry has many ways such

    as producing bread, yogurt, alcohol and some kind of cheese and

    even we use another micro organism such as fungi in making

    another kind of cheese that we eat

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    Other micro organisms such as bacteria and fungi are sacrofibes

    that can decompose dead materials into nutrient for the soil such

    as sulfate and this help the soil to be much better

    Some micro organisms can produce nitrogen and give it to thesoil by taking it as a different formula from the formula that the

    soil needs , and there is some kind of bacteria that we can find it

    legumes and these bacteria provides the nitrogen for these plants

    and live in coexistence with these plants where these plant

    provide food for these bacteria and these bacteria provides

    nitrogen for it, and you can see then if you pull one of these

    plants from the soil as a bubbles thats found in the end of each

    root

    Bacteria and some other micro organisms produce anti-biotic to

    fight other types of bacteria and this is very important for us

    because we can use these anti-biotic to fight these bacteria if

    they harm us, we can imagine anti-biotic like anti bodies, where

    anti bodies attack and try to kill the cause of diseases and they

    act as soldiers, thats if they can, but if they cant we are going to

    use these anti bodies that has killed that bacteria before in killing

    the bacteria that cause us the disease

    Microbes and another micro organisms can be used in the genetic

    engineering where we can manipulate the genes that these

    bacteria carries getting these genes out replace with another

    genes and make the bacteria produce whatever we want and the

    best type of bacteria for this is Escherichia coli , many discovers

    things was reached because of this manipulating even sometimes

    scientist put genes that in our body and considering the type of

    genes that we mentioned , scientists study it a lot and they knoweach gene in it and what dose each gene produce such as

    proteins and other things , so thats why this kind of bacteria is

    very important for us in genetic engineering

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    Microbes are model cells that they help us to discover our cells

    and how they work because if we took a sample of cells and we

    put it under microscope we are just going to see nucleus,

    cytoplasm, and even some times some structure of the cells , but

    we will not be able to see the work that is being done inside ourcells , because there is a lot of work , such as what goes in the

    nucleus and outside of it , and what goes inside the cytoplasm

    and outside of it , and the process of transferring things between

    cells, but all of that we managed to know it by studying bacteria,

    because it helps us to know our body much more by manipulating

    it to our benefit , because they are easier to be studied

    Microbes and bacteria the pathogenic ones , they can cause

    diseases in two different ways , the first way is by the bacteria by

    itself, where it can pass the infection from one person to another ,

    because it has some weapons that it uses it in carrying disease or

    infection people. The second way is by releasing toxic materials

    thats are capable of destroying our cells by itself, and this

    bacteria can be in our bodies or in our skin or in the air

    Categories of diseases are two infection disease and microbial

    toxication

    For the infection diseases it happens by pathogenic colonizing,

    where the bacteria goes inside the body or outside and start to

    multiply, and they have different ways that helps them to stuck in

    our bodies, such as if they have special kinds of hands or methods

    thats make them stuck inside and outside the body and cant be

    removed by any fluid not even the blood or anything, and then

    they will keep in multiplying and make colonies, and once they do

    that, if a one cell of bacteria has a weapon that cause disease,this weapon will increase in number raising with it the

    opportunities in causing the disease and it will go and infect other

    people

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    The microbial toxication is where bacteria produced toxic caused

    disease, and this disease infect many other people, the best

    example for that is the wedding parties everywhere, but for

    Jordanian people we like to eat MANSAF ( abay sho kabse m3ay 3

    mansaf .. 1 am ) , (( 3omre ma shftha bs el Dr 7akatha )) , Mansafis being cocked in summer 6 hours before the wedding and its

    being put in the sunshine, some of the cockers may have Stafu

    urias and this goes inside mansaf and make a colony there and

    start producing toxic in the food, and when people eat this food

    they will have a food poisoning because ( mlabas 3 looz ) of this

    bacteria, and they will suffer from vomiting and other features of

    food poisoning

    First micro organisms was found before five billion years, even

    before human, and they are the reason of life on this planet, we

    discover this by studying micro organisms carbons fossils, but

    certainly they are not accurate, but we say that they are here

    since 3.5 billion years, and the eldest ones are Cyanc bacteria,

    Arohaeac, and for sure diseases was there since the human and

    animal were found on earth, but certainly these diseases were not

    known back there, but know we know them because we have

    advance technology and we considered ourselves the best and

    the most advanced civilization, and maybe there is some other

    bacteria we dont know about it, and we cant treat them now and

    know what is going to happen if we infected by them

    Scientist studied micro organisms by studying the dead bodies of

    ( el fra3na ) , and they discovered by doing X-rays and many

    other researches that they have ( ) and they died

    because of it, and we should know that these disease comes frommicro organisms

    Now we are going to talk about the people that we own them

    ( hye l7alha ) the preferred of studying micro organisms. The first

    one of them and he was the father of microscopes and the father

    of microbiology was Anton Von Leuwenhookin 1673, he was

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    not a scientist by its meaning, he didnt have a PhD in science but

    he was a thinker and an observative man, he used to play with

    lenses and he made the basic microscopes and the first ones, he

    used to draw whatever he observed, and he managed to discover

    protozoa and the first bacteria

    Louis Pasteur he was a French science in 1828, he was a

    chemist that works in fermentation to get the best kind of alcohol

    specially the wine by using bacteria because he was in the wine

    country France, fermentation can give us many things depending

    on the type of the microorganisms that has been used then he

    and others discovered acetone and propanol and steroids from

    fermentation, then he discovered the process of pasteurizing,

    here we are going to compare the difference between fresh milk

    and pasteurized milk, fresh milk when its boiled it loose a lot of

    proteins, but pasteurized milk kills the pathogenic organisms, so

    he was the one who discovered pasteurization, he also discovered

    Vaccine ( ) for Rabies ( ) and Anthrax (

    ), and that was for the first time, he also discovered that

    there is bacteria lives in O2 and one thats called Anaerobic that

    can live in the presence of oxygen, and some that can live in both

    environments.

    Robert Koch in 1843-1910, German physician, he put the

    method that says each disease has its own causes, he also

    discovered that some bacteria have spores and other doesnt

    have, in most condition the one that doesnt have it are harmless,

    but the others that have it are very harm full, because these

    spores are protein coats that let the bacteria survive more,

    because bacteria covers with these coats when the conditionaround it are not good like coldness and drought, and that let it

    stand for over 10 years, when it feels that the conditions around it

    is good it hatches this coat and goes into vegetative cells, normal

    bacteria cell, spores dont multiply but when they transform into

    vegetative cells they can multiply

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    He also discovered the Anthrax causes and thats been caused by

    Bacillus Anthracis and in the new technology has developed it to

    become a biologic weapon that people if they sniff it or digested

    it, it will directly produce killer toxins that kill us right away

    He also discovered the way to verification of bacteria by Kochs

    Postulates, and thats by Cultivation of bacteria ( sa77a daktora )

    His method was like this :

    First, he took a sample from spleen or blood or pus.

    Second, isolating bacteria from this sample.Third, growing this bacteria and cultivation then make sure that

    he has formed a pure culture that contains only one kind of

    bacteria.

    Forth, he plants this bacteria in another individual.

    Fifth, he makes sure that this individual had also been infected

    with this disease from the bacteria by having the same

    symptoms.

    Sixth, he took another sample and compared it under microscope

    with the first bacteria, and he found that some diseases have the

    same pathogenic cause, but others have more than one cause

    And he had a big role in microbiology

    In microbiology there is careers of diseases and the reason of

    getting infection is because of our immunity is weak or because of

    the micro organism is so strong that beats our immunity ( 5

    dgaayeg w el dktoora bt7ke neha nfsha tkon 3alme .. d3oolha :P ,

    w kul wa7d feko 7or w y5tar elle bdo yah )

    Microbiology consists ofmany branches:

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    1- Protozoa microbiology

    2- Virus microbiology

    3- Bacteria microbiology

    4- Microscopic microbiology

    5- Infection microbiology

    The last important thing is developing of Vaccines because there

    is new diseases that comes and all diseases that vanish but they

    are coming back, so we must develop new ways in microbiology

    to treat these diseases. ( etl3ooobrrrraaaaaaaaaaaa ) :PPPPP ::DDDDDDDDD

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    ZEZO NO LUCK(al7oot ) (abuadam ) (A7MAD FAWZI ) ::::: ba7eb

    ahde tafrege la akatr ensan ba7eboh beldof3ah w agla ensan w

    a7san ensan w b7eb a7kelo enoh lawla wjoodak b 7ayate kan ma

    enkatab hada eltafreeg wala kan 3melet eshe w (AKEED MA7A7KELKOM MEEN ) :p hadoool kolhom elak

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    but its really was hard because of the recorder

    anyway thanks a lot for every one work for us .. and we always

    have to be one hand to be the best and give the best :D

    Again and again THANKS ALL,Good luck, wish that we all will pass with a high marks this

    semester

    Finally, I apologize for anyone that I have made bad for him and I

    really didnt mean to do that, and apologize for the (BEEEH)

    lec. :P .. enjoy it to get it ^ _^

    MOHAMMAD A3RAJ ::::::: BEDESH AKTOB ESHE :p :p