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Meiosis 1.5.10

Meiosis 1.5.10. Mitosis vs. Meiosis Genetic constancy via replication Genetic diversity via recombination (shuffling) How many outfits can be made from

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Meiosis

1.5.10

Mitosis vs. Meiosis

• Genetic constancy via replication

• Genetic diversity via recombination (shuffling)

• How many outfits can be made from 5 pairs of pants and 5 shirts?

Mitosis vs. Meiosis

• Genetic constancy via replication

• Genetic diversity via recombination (shuffling)

• How many outfits can be made from 5 pairs of pants and 5 shirts?

• 5 x 5 = 25 possibilities• (Imagine the # of

possibilities with 25,000+ genes!)

Meiosis

• The process of cell division that reduces the chromosome # by 1/2

Meiosis

• The process of cell division that reduces the chromosome # by ½

• Only used in sexual reproduction (not in bacteria or other asexual reproducers)

Meiosis

• The process of cell division that reduces the chromosome # by ½

• Only used in sexual reproduction (not in bacteria or other asexual reproducers)

• In humans: – 46 chromosomes in somatic (body) cells -> 23

chromosomes in gametes (sex cells)– 2n -> 1n (diploid -> haploid)

Why Sexual Reproduction?

Why Sexual Reproduction?

• Why not?

Why Sexual Reproduction?

• Why not?– Only ½ of population

reproduces – less potential offspring

– Huge energy expenditure in offspring production

– Only get to pass on ½ of your genome

Why Sexual Reproduction?

• Why not?– Only ½ of population

reproduces – less potential offspring

– Huge energy expenditure in offspring production

– Only get to pass on ½ of your genome

• Why?

Why Sexual Reproduction?

• Why not?– Only ½ of population

reproduces – less potential offspring

– Huge energy expenditure in offspring production

– Only get to pass on ½ of your genome

• Why?– MUCH more variation

(genetic diversity)– The variation provides

the raw material for change, allowing species to survive changing conditions

Mitosis vs. Meiosis

Mitosis• Cell grows

• DNA Replication

• Cell prepares for division

Meiosis• Cell grows

• DNA Replication

• Cell prepares for division

Phase

G1

S

G2

Mitosis vs. Meiosis

Mitosis• Chromosomes

condense

• Chromosomes line up across middle of the cell

Meiosis• Chromosomes

condense and pair with homologue to form a tetrad

• Homologous chromosome pairs (tetrads) line up across middle

Phase

•Prophase I

(crossing overoccurs!)

•Metaphase I

Mitosis vs. Meiosis

Mitosis• Spindle fibers pull

sister chromatids towards opposite poles

• Nuclear membrane begins to re-form

• Interphase

Meiosis• Spindle fibers pull

homologous pairs towards opposite poles

• Nuclear membrane may temporarily start to form, but then the cell goes immediately into

• Meiosis II

Phase

•Anaphase I

•Telophase I

Meiosis II

• Very similar to mitosis, except there is no Interphase (no DNA replication)

Crossing Over

• The process of homologous chromosomes (one from mom and one from dad) swapping genes.

• Happens randomly at multiple spots on each chromosome

• Ensures genetic variation

Crossing Over

Crossing Over

End Results

Mitosis• 2 cells• 46 chromosomes (humans)• Diploid # of chromosomes• 2n # of chromosomes• Each cell is identical

Meiosis

End Results of One Round

Mitosis• 2 cells• 46 chromosomes (humans)• Diploid # of chromosomes• 2n # of chromosomes• Each cell is identical

Meiosis• 4 cells• 23 chromosomes (humans)• Haploid # of chromosomes• 1n # of chromosomes• Each cell has a unique

combination of genes