1

Annual

MCB Alumni

Newsletter MCB Molecular and Cellular Biology

The ARC Opens

Academic & Research Center offers MCB Faculty New Lab Facilities

This new 100,000 square-

foot, $35 million facility, a

partnership of the Russ

College of Engineering and

Technology and the College

of Osteopathic Medicine,

welcomed its first occupants

in winter 2010. The center

houses engineering classes

and research space, as well

as laboratories for medical

researchers. Major funding

for the project came from

the Osteopathic Heritage

Foundation and alumnus

Charles Stuckey Jr. and his

wife Marilyn. ..more

MCB Faculty Labs in the

ARC

Dr. Fabian Benencia

Dr. Karen Coschigano

Dr. Sharon Inman

Dr. Kelly McCall

Dr. Ramiro Malgor

Greetings Alumni and Friends of MCB!!! We are pleased to be publishing our fourth issue

of the MCB Alumni News! We hope that this

newsletter will remind you of friends and old

acquaintances, as well as keep you up to date on

what‘s new at MCB and Ohio University. Many

exciting changes have taken place over the last

year. First, I would like to mention that our

trusted MCB Administrative Assistant, Angie

Nilsen retired this past year. We wish her well!

Her position has been ably filled by Eileen

Schulz (see p. 22). In addition the MCB office

has moved to Porter Hall. MCB added two new

graduate faculty this past year (see p.2). The

addition of Monica Burdick, Assistant Professor,

Chemical and Biomolecular Engineering ex-

pands our interdisciplinary efforts with the Russ

College of Engineering and she will provide

MCB students and faculty alike with unique

approaches to solving biological problems. Kelly

McCall is a graduate of the MCB program, so

we were especially happy to welcome her as our

newest MCB graduate faculty member.

The listing of new students admitted to the pro-

gram since the fall of 2009 begins on p.3 of the

newsletter. Finally, we offer congratulations to

our recent graduates: (see p. 7) Juan Ding, Lu-

cila Sackmann, Wei Zeng, Yanyan Cao, Sulalita

Chaki, and Yanli Ding.

this issue

New Faculty P.2

New Students P.3

Student News P.6

Alumni News P.7

Research Highlights P.10

Grants Highlights P.12

MCB Alumni Board P.17

Publications / Grants / Honors P.18

I S S U E

D e c e m b e r 2 0 1 0

04

Fortunately, a few of our graduates are staying at

OU for postdoctoral training. The alumni news

starts on p. 7.

The MCB Program held a fall retreat October 23

in Baker Center on the OU campus. The retreat

included faculty research presentations in the

morning including presentations from Yunsheng

Li from Diagnostic Hybrids in Athens and Sudhir

Deosarkar of Interthyr – part of OU‘s Innovation

Center. We gratefully acknowledge the support

provided by Diagnostic Hybrids. Probably, our

most important new development this year is the

formation of the MCB Graduate Program Alumni

Board. Its founding members are: Tim Coleman,

Global Director, Rapid Testing Systems R&D,

Lonza Bioscience, Inc.; Paul Harding, Associate

Professor, Department of Zoology, Miami Uni-

versity; Tim Shannon, Associate Professor, De-

partment of Biology, Francis Marion University;

Xinzhong Wang, Principal Scientist at Biogen

Idec Inc. and Wenxian Sun, Professor, Depart-

ment of Plant Pathology, China Agricultural Uni-

versity. One of the first goals of the Alumni

Board will be to improve communication/contact

between MCB alumni.

Wishing you Happy Holidays and a Prosperous

New Year!

Bob Colvin

2

Research Activities

Glycoconjugate mediators of cell trafficking in cancer metastasis. Biochemical and biophysical

regulation of cancer stem cell phenotype. Adhesion of tumor cells to endothelium and vascular cells

under hydrodynamic shear stress.

Research Topics

Breast cancer, head and neck cancer, cancer stem cells, metastasis, cell adhesion

read more about Dr. Burdick here

New MCB Faculty

Monica Burdick, PhD

Russ College of

Engineering and

Technology

Chemical and Biomolecular

Engineering

burdick@ohio.edu

Dr. Monica Burdick became a

member of the MCB faculty in Octo-

ber 2009. She earned her Ph.D. in

Chemical and Biomolecular Engi-

neering from Johns Hopkins in 2003,

and her B.S. in Chemical Engineer-

ing from the University of Roches-

ter, where she minored in chemistry

and economics and earned a certifi-

cate in biomedical engineering. Fol-

lowing her Ph.D., she became a post-

doctoral research fellow at the Har-

vard Medical School and Brigham

and Women's Hospital in Boston,

MA. She is currently an assistant

professor in Chemical and Bio-

molecular Engineering

Kelly McCall, PhD

College of Osteopathic

Medicine

Department of Specialty

Medicine

mccallk@ohio.edu

Dr. Kelly McCall became

a member of the MCB faculty

in October 2009. She earned

her Ph.D. in Molecular and

Cellular Biology from Ohio

University in 2003, and her

B.S. in Biological Sciences

from Ohio University in 1997.

She is currently an assistant

professor of endocrinology in

the Ohio University College of

Osteopathic Medicine.

Research Activities

Dr. McCall‘s research currently focuses on the pathogenesis of autoimmune-inflammatory diseases

including both type I and type II diabetes, a variety of human cancers (i.e. thyroid, pancreatic, pros-

tate, breast, colon, and malignant melanoma), colitis, toxic shock, and atherosclerosis. Specifically,

Dr. McCall‘s laboratory is focused on Toll-Like Receptors and their involvement in the pathogenesis

and progression of the aforementioned diseases.

Research Topics

Diabetes, inflammation, autoimmune disease, tumor biology, innate immunity, small molecule ther-

apeutics.

read more about Dr. McCall here

3

Debarati Basu I joined the MCB PhD program at Ohio University in Fall 2009. My

home department is Environmental and Plant Biology (PBIO) and I am in

Dr. Allan Showalter‘s lab. I obtained my master‘s degree in Botany from

University of Calcutta in India. I am interested in Arabinogalactan pro-

tein biosynthesis in Arabidopsis. Currently, I am working on identifica-

tion and characterization of Arabinogalactan-protein Galactosyltransfer-

ase mutants in Arabidopsis

New Students 2009

Yanrong Qian I graduated from Shanghai University, China. I joined Dr. Xiao Chen's

lab in 2009 fall. Now, I am interested in the anticancer mechanisms of

compounds which can inhibit cancer cell growth through inhibiting can-

cer cell's glucose uptake.

Lingying Tong I received my Bachelor of Science Degree from the Department of Biochem-

istry, the Chinese University of Hong Kong. I joined Dr. Shiyong Wu‘s la-

boratory as a graduate student in the MCB program/Department of Chemis-

try and Biochemistry in 2009. One of my current research projects is to

identify the role of NOS and oxidative stress in UV-induced NF-κB activity.

Aditi Vyas I received my undergraduate education and Master's degree in Genetics

from India. I started my graduate study in the MCB program at Ohio Uni-

versity in the Fall of 2009. I did rotations in the laboratories of Dr. Soichi

Tanda and Dr. Mark Berryman. In the Spring of 2010 I decided to join Dr.

Soichi Tanda's laboratory, and currently I am working with him in under-

standing the effect of Jak/Stat pathway on Drosophila larval hematopoeisis,

and finding repressors that may have roles in modulating this pathway.

4

Amrita Basu After doing my undergrad study with a major in Zoology and MS in Biochem-

istry from India, I joined OU in 2009 Fall and MCB in the Fall of 2010. Cur-

rently I‘m working under Dr. John Kopchick and my research area focuses on

growth hormone and physiological changes related to the changes in the hor-

mone level.

New Students 2010

Pooja Bhatt I am originally from Mumbai, India and I joined Ohio University as a PhD

student to work with Dr. Doug Goetz. I have completed both, my Bachelor‘s

and Master‘s degree in Biochemistry from India. My research focuses on de-

termining the role of a specific protein in the pathogenesis of atherosclerosis.

Chunxi Zeng After obtaining my BS in Biotechnology in China in 2004, I had worked

for several years. I used to work in biological products institute as a techni-

cian. Then massive Sichuan earthquake in 2008 made me to engage in dis-

aster relief by joining Save the Children UK China Program first as a vol-

unteer later as a staff.

I came to Ohio University in 2009 to pursue the fascinating Molecular and

Cellular Biology study for PhD. I am currently working in Dr. Jennifer

Hines‘ lab focusing on T box transcription antitermination riboswitch

mechanism existing in many gram-positive bacteria. We want to develop

new antibiotics based on such mechanism in the future.

5

2010 Continued

Maria Muccioli I received my B.S. degree in Biochemistry from Suffolk University in

Boston in 2009. Here at OU, I am currently working in the laboratory of

Dr. Fabian Benencia investigating the role of TLR-3 signaling in murine

ovarian cancer cells. My interests are primarily in biomedical research,

specifically uncovering novel targets for drug development. After the

completion of my Ph.D. in Molecular and Cellular Biology I hope to

spend time on medicinal research while teaching at a university.

Craig Schenck

I recently received my undergraduate degree from Ohio University in cell

biology and biotechnology and am back for more. I'm currently working

on identifying proteins involved in the signal transduction phase of a

plant's response to gravity. I am also interested in the use of genetic engi-

neering for crop improvement. In my free time I love to travel and enjoy

running.

Alastair Plant

I completed a BSc in Biology at the University of Leeds, UK, and joined

the Gleissberg Laboratory as a doctoral student in 2010. My studies focus

upon floral and leaf morphology in an evolutionarily relevant plant spe-

cies, the basal dicot Eschscholzia californica. I am particularly interested

in the developmental mechanisms behind leaflet initiation in compound

leaves and wish to continue academic research in plant development after

graduation.

Xiao Liu Hello, I'm Xiao Liu. I am a new Ph.D. student at Dr. Showalter's lab. I'll be

doing some research on the proteins associated with plant cell wall. I'm from

China. My hobby includes running, hiking, and reading. I loved OU and the

Athens area immediately upon arrival!

6

Student Highlights

Conny Bartholmes:

MORPH Grant to attend the Molecular and Or-

ganismal Research in Plant History (MORPH)

workshop "The Leaf: Integrating Evolution, De-

velopment, and Function" (January 29-31st,

2010) in Boulder Colorado.

Mohor Chatterjee:

J.Robi Vestal Award for Best Environmental or

Evolution Poster in OBASM, 2009.

Yanyan Cao:

Second place in Biomedical Sciences,

Research and Creativity Fair, Spring 2009, Ohio

University

Brian Keppler: Second place, Environmental and Plant Biology,

Research and Creativity Fair, Spring 2009, Ohio

University

Pooja Majmudar:

Second place, Chemistry and Biochemistry, at the

Research and Creativity Fair, Spring 2009, Ohio

University

Yanrong Qian:

2009-10 Winner, Ohio University Graduate

Associate Outstanding Teaching Award

(GAOTA)

Carolina Sempertegui:

Second place, Biological Sciences, at the Re-

search and Creativity Fair, Spring 2009, Ohio

University.

Lucila Sackmann Sala:

Research Fellowship; Diabetes Research Initia-

tive (DRI) at Ohio University; $ 9,000

Presidential Poster Competition Winner; Endo-

crine Society, 91st Annual Meeting (ENDO 09),

Washington DC.

Student Enhancement Award; Vice President for

Research at Ohio University; $ 5,100. 01/2009 –

Graduate Assistantship; BioMolecular Innovation

and Technology Partnership (BMIT) at Ohio Uni-

versity; $ 20,000.

Conny Bartholmes

DONALD CLIPPINGER

FELLOWSHIP 2010-2011

OCEES

GRADUATE RESEARCH

FELLOW 2009-2010

Kaiyu Shen:

Student Enhancement Award, supporting student

research, in the amount of $6,000

Wei Zeng:

First place, Environmental and Plant Biology, at

the Research and Creativity fair, Spring 2009,

Ohio University

Nan Jiang

Presented posters at the 2010 American Society

of Plant Biologist, meeting in Montreal Canada

Yan Liang

7

2010 Juan Ding I am currently a post doctoral research fellow at Dr. John Kopchick's lab, Ohio Uni-

versity. I graduated in summer 2009 with a dissertation titled 'Biomarkers of growth

hormone and aging', in which I described potential blood marker proteins in response

to chronic growth hormone elevation, lack of growth hormone action, short term in-

jection of growth hormone, as well during normal aging in mice. At the present I am

working on a project to create a transgenic mouse model of aging, hopefully to uncov-

ering a therapeutic target for aging. Pictured here are my husband and myself at the

commencement ceremony June 2010.

Recent Graduates

2010 Lucila Sackmann My dissertation focused on white adipose tissue (WAT) of growth hormone receptor

knockout (GHR-/-) and wild-type mice of different ages (adult and aged). I used pro-

teomics to analyze the protein profiles of four WAT depots, comparing them amongst

themselves and looking at the influence of age and /or genotype. It is very interesting

to study WAT of GHR -/- mice because although they are obese, they also live longer

than wild –type mice, so the link between obesity, disease and premature death is not

present in these mice. Thus, the research involves a mix of components such as endo-

crinology, disease and aging. After graduation, I‘m staying for some time as a post-

doc in Dr. Kopchick‘s lab and in the meantime I‘m working out the details of a post-

doc position in Paris for next year. I was very proud to receive this year‘s Outstand-

ing Doctoral Student for the Department of Biological Sciences.

2010 Sulalita Chaki I am now working as research coordinator in a lab at the Beckman Institute, Univer-

sity of Illinois at Urbana Champaign. The lab I am engaged in now, works with mice

-wild type and knock out. They run projects to study several proteins in mice brains.

I am performing techniques like western blotting, immunoflorescence along with

taking care of mice colonies and genotyping.

2009 Wei Zeng Currently I am working at the Penn State University as postdoc and I will move to

University of Melbourne, Australia as a carbohydrate biochemist (a postdoc position)

starting from February 2011. I will continue working on plant cell wall biosynthesis

which I started while at Ohio University.

8

2006 Dustin Thomas I graduated from the MCB program in November of 2006 with a Master's degree studying

under Dr. Colvin. I examined the role the zinc transporter, ZnT1, plays in neuronal home-

ostasis. For the past two years, I have been studying the role of the Intracellular Domain

of the Amyloid Precursor Protein (AICD) that is associated with Alzheimer's Disease. The

work has been done in Dr. Sanjay Pimplikar's lab at the Cleveland Clinic. We used vari-

ous models to determine AICD's role including in vivo mouse work and tissue culture, all

of which indicates the peptide's possible hand in the neuroinflammation seen in the dis-

ease. During that time of work, I got married to my wife, Jill in October 2009 and bought

a house in Fairview Park, Ohio where we live with our two dogs and two cats. Also re-

cently, I began my studies to pursue my PhD at the Cleveland Clinic in their new Molecu-

lar Medicine Program. Things are just starting and I do not have a particular project yet,

but I can already tell it's going to be quite rewarding. I look forward to getting my work

underway.

Alumni News

2006 Liang Huang It‘s so wonderful to hear from MCB again. I am still working as a postdoctoral fellow in

the Laboratory of Molecular Pharmacology, National Cancer Institute, National Institutes

of Health. My current research focuses on 1) epigenetic regulation of gene expression and

the molecular mechanism of gene silencing; 2) using replicators as a tool in gene therapy;

3) and the identification of proteins that regulate replication initiation and timing. Studies

in methylation-dependent gene silencing won me the 2011 Fellows Award for Research

Excellence from NIH.

This year, I co-chaired NCI's annual Fellows and Young Investigators Colloquium, which

was held in Hershey, PA from March 17 through March 19. The three day conference was

quite successful with a record-breaking attendance of more than 400 people. Earlier this

year, I met Drs. Soichi Tanda and Mark Berryman when they were attending the fly meet-

ing in DC. It was so nice talking to them. I also met MCB alumni Ying Shen, Yanyan

Cao, Yanli Ding in the past year. I am always happy to speak with old friends, so please

feel free to visit us if you are coming to the DC area.

We are all doing very well, and of course the little one is always making lots of trouble.

Best Liang

2009 Yanli Ding I joined the MCB program in 2004 and received my Ph.D degree in 2009. Those years

that I spent in quiet and beautiful Athens were the most enjoyable years. The MCB pro-

gram and Department of Biological Sciences are so nurturing and friendly to international

students. The curriculum is well arranged to help international students to pass the most

difficult first year. Faculty and staff are always ready to help. Now I am a postdoctoral

research fellow in Brigham and Women‘s Hospital of Harvard University. My study is

focusing on anion transporters involved in kidney diseases. Boston is a dynamic big city

and long wood medical area is full of academic activities. But I still miss Athens, and

OU. I wish new MCB students will enjoy student life at OU as much as I did.

Best regards,

Yanli

9

2005 Bethany Henderson-Dean I received tenure and promotion at the University of Findlay in the 2009-2010 academic year.

I am an associate Professor of Biology and Chair of Natural Sciences

Alumni News

2007 Akwasi Agyeman I graduated in 2007 and am currently a postdoctoral fellow at the Lerner Research Institute of

the Cleveland Clinic Foundation. My current line of research is on the study of the molecular

mechanisms underlying human colorectal cancer. My involvement in this study has generated

two important publications in JBC and PloS ONE on which I am a co-author.

I got married in 2008 and was blessed last year with a wonderful daughter named NanaYaa

Benewaah Agyeman.

I am grateful for the continuous support from the program and the Professors even long after

graduation.

I wish everybody the best luck in their endeavors.

Akwasi

In Memory

Ziqi Liu Ziqi joined my lab in January of 2010. Everyone who worked with Ziqi enjoyed his cheerful

energetic personality and his enthusiasm for life. Ziqi‘s research was focused on a human

cytomegalovirus gene that down regulates recognition of virally infected cells by the immune

system. Part of his research characterizing the gene in clinical isolates of the virus led to a

publication in the International Journal of Biochemistry and Cell Biology (Liu, Z., Winkler,

M. and Biegalke, B. (2009) Human cytomegalovirus: Host immune modulation by the viral

US3 gene. Int. J. Biochem. Cell Biol. 41:503-506). In addition to characterizing clinical

isolates, Ziqi made a specific mutant virus that over-expresses the immune evasion

gene. This mutant virus replicates with decreased efficiency; these results were presented as

poster at the International Herpesvirus Workshop (Liu, Z. and Biegalke, B.J. Over-

expression of the human cytomegalovirus US3 gene inhibits viral replication. 35th Annual

International Herpesvirus Workshop, Salt Lake City, Utah, 2010).

Ziqi Liu 1981—2010

Shiyan, Hubei,

P.R. China

Ziqi was diagnosed with malig-

nant, metastatic osteosarcoma in

the spring of 2008. Despite a val-

iant effort to overcome the disease,

Ziqi succumbed to complications

of his cancer in 2010. He is

missed by all who knew him.

Dr. Bonita Biegalke

10

Research Highlights

Dr. Ahmed Faik:

Building Blocks: Understanding how plants create cell walls could improve

food, biofuel production.

What do candy, cosmetics, T-shirts, and paper have in common? They‘re all

derived from cell walls—tough structures surrounding plant cells that

influence cell shape, growth, and communication. Found in plants but not

animals, cell walls help woody stalks stand tall and make almonds harder

than apples.

―We are eating cell walls, we are wearing cell walls, and yet we don‘t under-

stand how plant cells build these complex structures outside themselves,‖

says Ahmed Faik, an Ohio University associate professor of environmental

and plant biology. Faik‘s laboratory is dedicated to finding out how plant

cells make cell walls. He knows that cells dispatch specific worker proteins

called glycosyltransferases (a type of enzyme) to tack on the walls‘ main

ingredients, sugars. It takes about 100 different enzymes, each with its own

specific function, to build a wall. So far, says Faik, researchers have discov-

ered the function of only a dozen of those

enzymes. ...Read the full story in Perspectives F 10‘ here.

Dr. Lisa Crocket:

Life Under Ice: Biologist Lisa Crockett explores how the unusual icefish survives

the frigid climate of Antarctica. In the frigid waters of the Southern Ocean there

lives an extraordinary group of fishes with blood as white as snow. Known as the

icefishes, the group lacks hemoglobin, the iron-containing protein that transports

oxygen throughout the bodies of red-blooded animals and gives their blood its ruddy

color.

―The icefishes are an exceptional group of animals,‖ Crocket says. ―They are the

only vertebrates in the world that lack hemoglobin as adults. My goal is to find out

whether the lack of hemoglobin provides some benefit to the animals.‖

According to Crockett, scientists previ-

ously assumed that there must be an en-

ergy advantage associated with the loss

of hemoglobin in the icefishes. Perhaps

without hemoglobin, the blood is less

viscous and, therefore, easier to pump?

they wondered. But research eventually

revealed that to compensate for the lack

of hemoglobin, the icefishes evolved a

number of traits, including a massive

heart with which to pump large volumes

of blood to their tissues…

Read the full story in

Perspective F 10‘ here

11

Dr. Shiyong Wu / Dr. Tadeusz Malinski:

Wu and Malinski‘s current research is focusing on Ultravi-

olet light (UV)-damaged skin has an increased chance of

developing one of the forms of skin cancer, including basal

cell carcinoma, squamous cell carcinoma and cutaneous

malignant melanoma. The apoptoic response to UV is a

protective response that eliminates cells that receive high

doses of UV. Dr. Wu teamed with Dr. Malinski (also a

MCB member) proposed to study the mechanisms that reg-

ulate UV-induced apoptosis via nitric oxide synthase medi-

ated signaling pathways and to determine the roles of nitric

oxide/peroxynitrite in UV-induced translation regulation

and apoptosis. Their collaborative work has been selected

as cover story on American Society for Photbiology (ASP)

website.

Dr. Robert Colvin:

“Where are they Now”

More than 10 years ago, Robert Colvin and colleagues tried to find the genes responsible

for the memory loss that comes with aging. In an experiment led by now-retired faculty

member Linda Bellush, the team tested how well older mice with and without signs of cog-

nitive decline could remember how to swim a water maze. Read how a fateful meeting

between Colvin and scientist and OU alumnus Matt Huentelman brings about a new col-

laboration that takes advantage of todays technology.

Read the full story in Perspectives A/W 09‘

Research Highlights

Dr. Steve Bergmeier and Dr. Mark McMills:

“Battling Superbacteria”

It‘s a nightmare for hospitals: the rise of ―superbacteria‖ that can thwart all conventional

antibiotics. And though these potent strains are on the rise, no new chemical class of anti-

bacterial compounds has been developed since the 1960s. Steve Bergmeier and colleagues

are looking to nature for a solution. Bergmeier and fellow Ohio University chemistry pro-

fessor Mark McMills and Nigel Priestley from the University of Montana are developing a

class of new anti-bacterial compounds developed from molecules made by bacteria them-

selves. In the laboratory, the scientists tear the molecules apart and reassemble them in

ways to design more potent agents against bacteria such as methicillin-resistant Staphylo-

coccus aureus (MRSA), more commonly known as a ―staph infection.‖ MRSA can cause

serious illness and even death. ...read the full story in Perspectives Sp/Su 10‘

Matt Huentelman studies the human genome to advance diagnosis and treatment of disease. Photo by Mark Skalny / Mark Skalny Photography

12

Dr. Mario Grijalva MCB 96’ and Dr. Jaime Costales MCB 05’

are pictured here during a press conference in Manabi Ecuador:

Mario Grijalva, of the Tropical Disease Institute was awarded a five-year NIH

grant to be used to expand the Ecuadoran research training center and will help

researchers obtain biological and clinical information to improve Chagas disease

control and implement a training program in infectious disease research….

read the full story at OUCOM here.

Grants Highlights

Dr. Fabian Benencia was awarded a two-year, $177,000 NIH grant to study

how tumors attract leukocytes, or white blood cells, and use them for their own

designs He also received a grant from the National Science Foundation (NSF) to

purchase a state-of-the-art flow cytometer with cell-sorting capabilities. The flow

cytometer will enable students and researchers to look at the size, shape and mo-

lecular content of cells...read the full story at OUCOM here

Dr. John Kopchick discovered a growth hormone receptor antagonist that led

to the development of the FDA-approved drug Somavert. Since that time,

Kopchick‘s team has explored how the technology might be effective in the treat-

ment of diabetes and cancer. In 2009, Dr. Kopchick received a $1.7 million grant

from the National Institutes of Health to explore the impact of growth hormone on

aging...read the full story at OU Research here

Dr. Doug Goetz is working with the Interthyr Corporation to develop a novel

therapeutic that blocks abnormal expression of toll-like receptors and may offer a

new type of treatment for autoimmune diseases such as diabetes, colitis, and certain

types of cancers that express these receptors. The team received a $2.6 million Na-

tional Institutes of Health STTR grant in 2009 to help advance the project to clini-

cal trials… read the full story at OU Research here.

13

Grants Highlights

Dr. Robert Colvin: ―Characterizing the effects of alcohol exposure on develop-

ing neurons," Ohio University Research Committee, $8,000, Principal Investigator.

Developing neurons are continuously forming new connections between each other

in order to establish communication, excreting growth factors, and adapting to the

environment surrounding each specific cell. Neurons are particularly sensitive to

disruption during the first days of growth when they begin to form synaptic con-

nections with other neurons. Many of the connections are intended to be permanent

and to function for an entire human life. Different molecules and stimuli can nega-

tively or positively affect neuron synapse formation, potentially resulting in altered

connectivity that could cause changes in the functional capabilities of the adult

brain. The studies to be carried out for this OURC grant use an in vitro cell culture

model of neuronal development to better understand the effect(s) of alcohol at the

critical period when neurons are forming synapses. The goal of these studies is to

characterize the actions of alcohol on synapse formation and determine when de-

veloping neurons are most sensitive to alcohol's actions as a model of fetal alcohol

spectrum disorder (FASD)

Dr. Morgan Vis, received a NSF grant entitled ‗Collaborative Research:

RedToL - Phlogenetic and Genomic Approaches to Reconstructing the Red Algal

(Rhodophyta) Tree of Life‘ with three other colleagues in the US and two interna-

tional collaborators. I am very excited about the opportunity this grant affords our

potential to answer significant questions regarding the evolution of red algae. The

research is a two-pronged approach to understanding relationships within this im-

portant group of algae, which provide us with sushi wrappers, and agar among

other products. First, we will be sequencing 8 genes from the nuclear, mitochon-

drial and plastid genomes from ~500 specimens to build robust phylogenetic trees.

Secondly, 16 plastid genomes will be generated for important taxa so that red algae

will be brought into the genomic age along side vascular plants that have had nu-

merous chloroplast genomes already produced. For my research in particular, this

grant affords me the opportunity to interact with colleagues from all over the world

and put my research on freshwater red algae (5% of the species) in a larger context

with the marine red algae, which are far more numerous. We are still early in the

research, but we have already made great strides in getting sequence data from

numerous genes. Much of the data has been generated by research experience for

undergraduate (REU) students, graduate students and postdoctoral researchers in-

volved with the grant. We hope to have significant research papers out soon.

14

Grants Highlights

Dr. Matthew White: Dr. White‘s lab uses molecular markers to understand

population differentiation in freshwater fishes. He recently received grants from

Kentucky and West Virginia as part of some long-term funding to study mito-

chondrial DNA sequences and DNA microstellite variation to understand the

distribution of native walleye. The works differentiates pure native individuals

from introduced fish for use in fisheries management and regional stocking. Our

data helps to direct hatchery practices in both states. The work is expanding to

include muskellunge management in the Ohio River drainage.

Dr. Shawn Chen: Award from the American Heart Association, titled " Bio-

synthesis of Albomycin and the Applications in Biotechnology".

Albomycin is a Trojan horse antibiotic that inhibits seryl-tRNA synthetase. It

has a chemical structure of a modified peptidyl nucleoside linked to a sidero-

phore. Its antibacterial potency is at least 1,000-fold stronger than any antibi-

otic on the market. We will study the enzymology and biosynthetic pathway of

albomycin, carry out metabolic engineering of the producing microbe to im-

prove the yield of albomycin, and use genome mining to discover microbial

natural products that are aminoacyl-tRNA synthetase inhibitors.

15

The MCB Program fall retreat was held Saturday, October 23, Baker Center

240/242, Ohio University. This was a successful event that brought together stu-

dents, faculty and alumni associated to the program. Hosting more than 50 attend-

ants, the morning activities were devoted to several scientific talks given by our

diverse faculty. The presentations involve studies dealing with RNA modulators,

plant cell wall biology, bacterial gene regulation, growth hormone biology, signal-

ing pathways in atherosclerosis, and adhesion molecules associated to cancer stem

cells. We were also fortunate to have speakers from two OU-associated companies,

Interthyr and Diagnostics Hybrids, the latter one also being a sponsor for this event.

A highlight of the day‘s activities was a lunch time panel discussion moderated by

Dr. Colvin, whose topic was: How to prepare for post graduation? The panel mem-

bers were MCB alumni: Dr. Tim Coleman, PhD. (Scientist and senior manager,

Lonza Walkersville, Inc.); Dr. Paul Harding, PhD. (Associate Professor, Department

of Zoology, Miami University, Ohio); and Dr. Xinzhong Wang, PhD. (Principal

Scientist, Biogen Idec Inc., Cambridge, MA). An engaging discussion between

MCB alumni and current students ensued.

Finally, in the last activity of the afternoon a busy poster section gave the students

the opportunity to present their current research studies.

Faculty and Student Mini Retreat

2010

16

2010 Retreat

Dr. Monica Burdick

Ramiro Malgor, MD Dr. Erin Murphy

Dr. Yunsheng Li Dr. John Kopchick

Dr. Jennifer Hines

Dr. Ahmed Faik

Presentations

Poster Presentations

17

MCB Alumni

Board

Dr. Paul Harding, / MCB Retreat

Dr. Tim Coleman and Dr. Xinzhong Wang /

MCB Retreat

Dr. Xinzhong Wang /MCB Retreat

Tim Coleman, PhD, MCB 91’ Global Director, Rapid Testing Systems R&D,

Lonza Bioscience Inc., Walkersville, MD (Scientist and senior manager with

more that 15 years experience in biotechnology and biopharmaceutical organi-

zations including Human Genome Sciences (HGS), Correlogic Systems, Inc.,

Lonza Walkersville, Inc. His area of expertise include genomics, proteomics,

molecular biology, recombinant protein expression, purification and characteri-

zation).

Paul Harding, PhD, MCB 94’ Associate Professor, Department of Zoology,

Miami University, Ohio. Dr. Harding is a molecular and cellular biologist who

is interested elucidating the in vivo roles of heparin-binding EGF-like growth

factor (HB-EGF).

Tim Shannon, PhD, MCB 98’, Associate Professor Department of Biology,

Francis Marion University, Florence, SC

Wenxian Sun PhD, MCB 03’, Professor, Department of Plant Pathology, Chi-

na Agricultural University, Beijing, P.R. China

Xinzhong Wang, PhD. MCB 93’ Principal Scientist at Biogen Idec Inc., Cam-

bridge MA, with a focus in tumor with the aim to develop novel therapeutics

for cancer treatment. Biogen Idec is a biopharmaceutical company focused on

the development of drugs on five therapeutic areas: Neurology, Immunology,

Oncology, Cardiopulmonary and Hemophilia.

Improve communication/contacts between MCB Alumni

Review MCB curriculum and provide feedback as to the competitiveness

of the resulting graduates for further academic pursuits or entering the job

market.

Review, evaluate and advise on long-range plans for the MCB graduate

program.

Review, evaluate and advise on resource allocations.

Support recruiting of high caliber graduate students.

Coordinate fund-raising among the alumni and other outside sources.

Contact Us http://www.ohio.edu/mcb/alumniComments.cfm

Founding Board Members

Alumni Board Mission

18

Publications 2010

Ballard, Harvey: Havran, J. C., H. E. Ballard, and K. J. Sytsma. 2009. Evo-

lutionary relationships, interisland biogeography, and mo-

lecular evolution in the Hawaiian violets (Viola: Violace-

ae). American Journal of Botany 96: 2087-2099.

Wahlert, Gregory A. and H. E. Ballard, Jr. 2009. A new

zygomorphic-flowered Rinorea (Violaceae) from the Neo-

tropics. Brittonia 19: 416-420.

Bergmeier, Stephen:

Inhibitors of basal glucose transport as potential anticancer

agents. W. Zhang, Y. Liu, X.Chen & S. C. Bergmeier,

Bioorg Med. Chem. Lett. 2010, 20, 2191-2194.

Natural Product Derivatives with Bactericidal Activity

Against Gram-positive Pathogens Including Methicillin-

resistant Staphylococcus aureus and Vancomycin-resistant

Enterococcus faecalis. N. D. Priestley, J. B. Phillips, A. E.

Smith, B. R. Kusche, B. A. Bessette, P. W. Swain, S. C.

Bergmeier, M. C. McMills, & D. L. Wright Bioorg Med

Chem Lett. 2010, 20, 5936-5938.

A library of 1,4-disubstituted 1,2,3-triazole analogs of

RNA-binding oxazolidinones. G. Acquaah-Harrison, S.

Zhou, J. V. Hines & S. C. Bergmeier, J. Comb. Chem.

2010, 12, 491-496.

Inter- and Intramolecular reactions of epoxides and aziri-

dines with π-nucleophiles (Invited Review), S. H. Krake &

S. C. Bergmeier, Tetrahedron 2010, 66, 7337-7360.

Negative Allosteric Modulators that Target Human α4β2

Neuronal Nicotinic Receptors. B. J. Henderson, R. E. Pav-

lovicz, J. D. Allen, T. F. Gonzalez-Cestari, C. M. Orac, A.

B.Bonnell, M. X. Zhu, R. T. Boyd, C. Li, S. C. Bergmeier,

& D. B. McKay, J. Pharmacol. Exp. Ther. 2010, 334, 761-

774.

Berryman, Mark:

Wegner, B., A. Al-Momany, S.C. Kulak SC, K. Ko-

zlowski, M. Obeidat, N.Jahroudi, J. Paes, M. Berryman,

and B. Ballermann. 2010. CLIC5A, a component of the

ezrin-podocalyxin complex in glomeruli, is a determinant

of podocyte integrity. Am J Physiol Renal Physiol.

298:F1492-1503.

Bradford, E.M., M.L. Miller, V. Prasad, M.L. Nieman,

L.R. Gawenis, M. Berryman, J.N. Lorenz, P. Tso, and G.E.

Shull. 2010. CLIC5 mutant mice are resistant to diet-

induced obesity and exhibit gastric hemorrhaging and in-

creased susceptibility to torpor. Am J Physiol Regul Integr

Comp Physiol. 298:R1531-R1542.

Ponsioen, B., L. van Zeiji, M. Langeslag, M. Berryman, D.

Littler, K. Jalink, W. Moolenaar. 2009. Spaciotemporal

regulation of chloride intracellular channel protein CLIC4

by RhoA. Mol Biol Cell. 20:4664-4672.

Colvin, Robert:

Colvin, R.A., Holmes, W.R., Fontaine, C.P., and Maret,

W. Cytosolic zinc buffering and muffling: their role in

intracellular zinc homeostasis. Metallomics 2:306-317,

2010.

Coschigano, Karen: Stevenson AE, Evans BAJ, Gevers EF, Elford C, McLeod

RWJ, Perry MJ, El-Kasti MM, Coschigano KT, Kopchick

JJ, Evams SL, and Wells T. (2009) Does adiposity status

influence femoral cortical strength in rodent models of

growth hormone deficiency? Am J Physiol Endocrinol

Metab, Jan 2009; 296: E147 - E156.

Coschigano, Peter: L. Li, D. P. Patterson, C. C. Fox, B. Lin, P. W. Coschi-

gano, and E. N. G. Marsh. 2009. The subunit structure

of Benzylsuccinate Synthase. Biochemisrty. 48:1284-

1292.

Faik, Ahmed: W. Zeng, N. Jiang, R. Nadella, TL Killen, V. Nadella, A.

Faik (2010) A glucurono(arabino)xylan synthase complex

from wheat (Triticum aestivum L.) contains members of

the GT43, 47, and 75 and functions cooperatively. Plant

Physiol 154: 78-97

Y. Wu, M. Williams, S. Bernard, A. Driouich, A.M.

Showalter, A. Faik (2010) Functional identification of two

non-redundant Arabidopsis alpha-(1,2)fucosyltransferases

specific to arabinogalactan-proteins. J Biol Chem, 285:

13638-13645

A. Faik (2010) Xylan Biosynthesis: News from the grass.

Plant Physiol 153: 396-402 (invited review)

Y. Liang, A. Faik, M. J. Kieliszewski, L. Tan, W-L. Xu,

Allan M. Showalter (2010) Identification and characteriza-

tion of in vitro galactosyltransferase activities involved in

arabinogalactan-protein glycosylation in tobacco and Ara-

bidopsis. Plant Physiol. doi 10.1104/pp.110.160051

Gleissberg, Stefan: Hidalgo O, Gleissberg S (2010): Evolution of reproductive

morphology in the Papaveraceae s.l. (Papaveraceae and

Fumariaceae, Ranunculales). International Journal of Plant

Developmental Biology 4 (Special Issue): 76-85

Ichihashi Y, Horiguchi G, Gleissberg S, Tsukaya H

(2010): The bHLH transcription factor SPATULA controls

final leaf size in Arabidopsis thaliana. Plant and Cell Phys-

iology 51: 252-261

19

Publications 2010

Goetz, Douglas: Kummitha C.M., K.M. Mayle, M.A. Christman 2nd, S.P.

Deosarkar, A.L.Schwartz, K.D. McCall, L.D. Kohn, R.

Malgor and D.J. Goetz. 2010. A sandwich ELISA for the

detection of Wnt5a. J Immunol Methods. 352(1-2):38-44.

Benavides U, M. Gonzalez-Murguiondo, N. Harii. CJ

Lewis, HS Sakhalkar, SP Deosarkar, DT Kurjiaka, NM

Dagia, DJ Goetz, LD Kohn. 2010. Phenyl Methimazole

Suppresses Dextran Sulfate Sodium-Induced Murine Coli-

tis. Eur J Pharmacol. 643(1):129-38.

Grijalva, Mario: Mario J. Grijalva, Francisco S. Palomeque, Anita G. Villa-

cís, Carla L. Black, Laura Arcos-Terán. 2010. Absence of

domestic triatomine colonies in an area where Chagas Dis-

ease is considered endemic in the coastal region of Ecua-

dor. Memorias do Instituto Oswaldo Cruz. 105(5): 667-

681.

Richard Reithinger, Mario J. Grijalva, Rosa F. Chiriboga,

Belkisyolé Alarcón de Noya, Jaime R. Torres, Norma Pa-

via, Pablo Manrique-Saide, and Ricardo E. Gürtler. 2010.

Rapid detection of Trypanosoma cruzi in human serum

using an immunochromatographic dipstick test. Journal of

Clinical Microbiology. 2010 Aug;48(8):3003-7.

Abad-Franch F, Ferraz G, Campos C, Palomeque FS, Gri-

jalva MJ, Aguilar HM, Miles MA.2010. Modeling dis-

ease vector occurrence when detection is imperfect: infes-

tation of Amazonian palm trees by triatomine bugs at three

spatial scales. PLoS Negl Trop Dis. 2010 Mar 2;4(3):e62

C. Miguel Pinto, B. Dnate‘ Baxter, J. Delton Hanson,

Francisca M. Méndez-Harclerode, John R. Suchecki, Mar-

io J. Grijalva, Charles F. Fulhorst, and Robert D. Bradley.

2010. Using Museum Collections to Detect Patho-

gens. Journal of Infectious Diseases. 16(2):356-357

Carla L. Black, Sofía Ocaña-Mayorga, Diana K. Riner,

Jaime A. Costales, Mauricio S. Lascano, Laura Arcos-

Terán, John S. Preisser, J. Richard Seed, and Mario J. Gri-

jalva. 2010. Seroprevalence of Trypanosoma cruzi in rural

ecuador and clustering of seropositivity within house-

holds. American Journal of Tropical Medicine and Hy-

giene. 81(6): 1035-1040.

Victoria Suarez-Davalos, Olivier Dangles, Anita G. Villac-

is, Mario J. Grijalva. 2010. Microdistribution of sylvatic

triatomine populations in Central-coastal Ecuador. Journal

of Medical Entomology. 47(1): 80-88

Gu, Tingyue: C.-X. Liang, Y.-B. Li, J.-W. Xu, J.-L. Wang, X.-L. Miao,

Y.-J Tang, T. Gu, J.-J. Zhong, "Enhanced Biosynthetic

Gene Expressions and Production of Ganoderic Acids in

Static Liquid Culture of Ganoderma lucidum under Pheno-

barbital Induction," Applied Microbiology and Biotechnol-

ogy, 86, 1367–1374 (2010).

J. Wen, K. Zhao, T. Gu, I. Raad, "Chelators enhanced bio-

cide inhibition of planktonic sulfate-reducing bacterial

growth," World Journal of Microbiology and Biotechnolo-

gy, 26, 1053-1057 (2010).

T. Gu, "Radial flow chromatography for bioseparations,"

in Encyclopedia of Industrial Biotechnology: Bioprocess,

Bioseparation, and Cell Technology, M. C. Flickinger

(ed.), Wiley, New York, 2010.

Kopchick, John: Berryman, D.E., List, E.O., Palmer, A.J., Chung, M.Y.,

Wright-Piekarski, J., Lubbers, E., O‘Conner, P., Okada, S.,

Kopchick, J.J. Two-Year Body Composition Analyses of

Long-Lived gHR Null Mice. J. Gerontol. A. Biol. Sci.

Med. Sci., 65(1):31-40, 2010.

Longo, K.A., Berryman, D.E., Kelder, B., Charoen-

thongtrakul, S., Distefano, P.S., Geddes, B.J., Kopchick,

J.J. Daily energy balance in growth hormone receptor/

binding protein (GHR-/-) gene-disrupted mice is achieved

through an increase in dark-phase energy efficiency.

Growth Horm. IGF Res., 20(1):73-79, 2010.

Okada, S., List, E.O., Sankaran, S. and Kopchick, J.J.

Plasma protein biomarkers correlated with the develop-

ment of diet-induced type 2 diabetes in mice. Clin Prote-

omics, 6(1-2):6-17, 2010.

Callewaert, F., Venken, K., Kopchick, J.J., Torcasio, A.,

van Lenthe, G.H., Boonen, S., Vanderschueren, D. Sexual

Dimorphism in Cortical Bone Size and Strength but not

density is determined by independent and time-specific

actions of sex steroids and IGF-1: Evidence from Pubertal

Mouse Models. J. Bone Miner Res., 25(3):617-26, 2010.

Kopchick, J.J., Martos-Moreno, G.A., Korbonitis, M.,

Gaylinn, B.d., Nass, R. and Thorner, M.O. Regulation of

growth hormone and action (segretagogues). Endocrinolo-

gy (Adult & Pediatrics) 6th Edition, Chapter 23, p. 412-

453, Saunders (Elsevier), Philadelphia, 2010.

Doi, S.Q., Chilakamarri, G.C., Mendonca, M.C., Araujo,

M., Nguyen, N., Zuhl, I., List, E.O., Kopchick, J.J., Hirata,

M.H. and Sellitti, D.F. Increased class A scavenger recep-

tor and glomerular lipid precede mesangial matrix expan-

sion in the bGH mouse model. GH IGF Res., 20(4):326-

332, 2010.

Rouet, V., Bogorad, R.L., Kayser, C., Kessal, K., Genestie,

C., Bardier, A., Grattan, D.R., Kelder, B., Kopchick, J.J.,

Kelly, P.A., Goffin, V. Local prolactin is a target to pre-

vent expansion of basal/stem cells in prostate tumors.

PNAS, 107(34):15199-15204, 2010.

20

Publications 2010

Kieliszewski, Marcia: Li Tan, Peter Varnai, Derek T.A. Lamport, Chunhua Yu-

an, Jianfeng Xu, Feng Qiu, Marcia J. Kieliszewski. O-

hydroxyproline arabinogalactans of arabinogalactan pro-

teins are B-(1-6) linked repeatsof -(1-3) trigalactosyl sub-

units with short bifurcated sidechains J. Biol. Chem. 285:

24575-24583

Xu J., Okada, S. Tan, L., Goodrum, K.J., Kopchick, J.J.,

Kieliszewski, M.J. (2010) Human growth hormone ex-

pressed in tobacco cells as an arabinogalactan-protein fu-

sion glycoprotein has a prolonged serum life. Transgenic

Research 19: 849-867

Kieliszewski, M.J., Lamport, D.T.A., Cannon, M., and

Tan, L. (2010) The extensins and arabinogalactan-

proteins: Structural motifs and post-translational codes. In

Annual Plant Reviews 41: Plant Polysaccharides (P.

Ulskov, ed.) Blackwell Publishing, LTD: Oxford; pp 319-

334.

Fernandes E, Soans E, Xu J, Kieliszewski M, Evans S

(2010) Novel fusion proteins of Interferon alpha 2b, cause

growth inhibition and induce JAK- STAT signaling in

melanoma. Journal of Immunology 33: 461-466,

Vis, Morgan: Smucker, N.J. & Vis, M.L. 2010. Using diatoms to assess

human impacts on streams benefits from multiple habitat

sampling. Hydrobiologia 654: 93-109.

Hollingsworth, E.K. & Vis, M.L. 2010. The spatial hetero-

geneity of diatoms in eight southeastern Ohio streams: how

far does a single riffle reach? Hydrobiologia 651: 173-184.

House, D.L., VandenBroek, A.M. & Vis, M.L. 2010. Intra-

specific genetic variation of Batrachospermum gelatino-

sum (Batrachospermales, Rhodophyta) in eastern North

America. Phycologia 49: 501-507.

Necchi, O. Jr., Vis, M.L. & Oliveira, M.C. 2010. Phyloge-

netic relationships in Kumanoa (Batrachospermales, Rhod-

ophyta) species in Brazil with the proposal of Kumanoa

amazonensis sp. nov. Phycologia 49: 97-103.

Zalack, J.T., Smucker, N.J. & Vis, M.L. 2010. Develop-

ment of a diatom index of biotic integrity for acid mine

drainage impacted streams. Ecological Indicators 10: 287-

295.

Wu, Shiyong: Wang L, Liu W, Parker SH, and Wu S*. Nitric oxide syn-

thase activation and oxidative stress, but not intracellular

zinc dyshomeostasis, regulate ultraviolet B light-induced

apoptosis. Life Sciences 2010, 86: 448–454.

Wu S., Wang L, Jacoby A, Jasinski K, Kubant R, Parker

SH and Malinski T. Ultraviolet B Light-Induced Nitric

Oxide/Peroxynitrite Imbalance in Keratinocytes – Implica-

tion in Apoptosis and Necrosis. Photochem Photobio.

2010, 86: 389–396.

Liu Y, Laszlo CF, Liu Y, Liu W, Chen X, Evans SC and

Wu S. Regulation of G1 Arrest and Apoptosis under Hy-

poxia by PERK and GCN2-mediated eIF2α Phosphoryla-

tion. Neoplasia 2010 12(1): 61-68.

Wang L, Liu Y and Wu S. The Roles of Nitric Oxide Syn-

thase and eIF2alpha Kinases in Regulation of Cell Cycle

Upon UVB-irradiation. Cell Cycle 2010 Jan 9(1): 38-43

Wyatt, Sarah: Wyatt, S.E., Sederoff, R., Flaishman, M., and Lev-Yadun,

S. (2010) Arabidopsis thaliana as a model for gelatinous

fiber formation. Russian Journal of Plant Physiology

57:384-388.

21

External Grants Honors

Ballard, Harvey: 2009/2012—National Science Founda-

tion, ―The Appalachian Ohio Herbarium Database Net-

work: Infrastructural Enhancements, Resource Building

and Database Completion‖; $494,019.

Bergmeier, Stephen, National Institutes of Health, Phase

II STTR (Interthyr Inc.)TLR Signal Inhibition: A Novel

Therapeutic Paradigm$166,728 – September 2009

Faik, Ahmed: National Science Foundation, REU:

Arabino (glucurono) Xylan Biosynthetic genes involved

in Endosperm cell wall elaboration in wheat. $6000.

Grijalva, Mario:

2010 – 2015. NIH. Regional Center for Training on Tropi-

cal Diseases in Ecuador. Global Infectious Disease Train-

ing grant D43. Role PI.

Kieliszewski, Marcia: NSF: Collaborative Research: Dissecting the Role of RSH

Extensin in Assembly of the Plant Cell Wall 50K

NSF: Collaborative Research: Extensin Modules Compris-

ing Self-Assembling Amphiphiles Create Scaffolds that

Nucleate Cell Wall Formation: Elucidation of Roles and

Rules 450K

McCall, Kelly 2009-2012 National Institutes of Health, Grant award TLR

Signal Inhibition: A Novel Therapeutic Paradigm,

$2.654, 929.42

Murphy, Erin: Research and Scholarly Affairs Committee Grant (3/2010)

―A Pilot Study of Establishing Real-time PCR Protocol for

intestinal microbial profile in older adults‖ ($6436.72)

Vis: Morgan: 2010. National Science Foundation (NSF), ―Collaborative

Research, RedToL - Phylogenetic and Genomic Approach-

es to Reconstructing the Red Algal (Rhodophyta) Tree of

Life,‖ REU supplement M.L. Vis $6,900.

White, Matthew: Genetic integrity of Rockcastle River, KY walleye. Ken-

tucky Department of Fish and Wildlife Resources, 2010-

2012. $6000.

Genetic analysis of native walleye in West Virginia. West

Virginia Department of Natural Resources. 2010. $2000.

Ballard, Harvey: 2009—University Professor Award

recipient, Ohio University

Coschigano, Karen: Promotion & Tenure awarded:

Associate Professor 2010

Faik, Ahmed: Promotion & Tenure awarded: Associate

Professor 2010

Elected to Sigma Xi 2010

Sugiyama, Tomohiko: Promotion & Tenure awarded:

Associate Professor 2010

22

414 Porter Hall

Athens, Ohio 45701

740.593.4170 ph

740.593.1569 fax

www.ohio.edu/MCB

New Addition to MCB

Research Facilities Ohio University Genomics Facility has acquired a new

Liquid Chromatography system. The new LC equipment

has been linked to the Esquire 6000 Mass spectrometer to

offer LC-MS proteomics service.

For more information contact Vijay Nadella

MCB Alumni News Issue 04 December 2010

Vijay Nadella

Genomics Facility 510 Porter Hall

nadella@ohio.edu

www.dna.ohiou.edu

Eileen Schulz

Administrative Assistant

414 Porter Hall

delehant@ohio.edu

Administrative Assistant

Eileen Schulz I am excited to be joining the Molecular and Cellular Biology

Program and working with the MCB students, faculty and

alumni. Please feel free to contact me if I can be of

assistance or to share your news.