Delivering research to make patients,

and the NHS, better

Maternity Clinical Network LAUNCH EVENT

Thames Valley & South Midlands CRN

18/07/2014

Manu VatishDivisional Lead Reproductive HealthNational Specialty Lead for Reproductive HealthNIHR CRN Thames Valley and South Midlands

What, who and why?

Delivering research to make patients,

and the NHS, better

Clinician An Obstetrician with over 10 years experience as a consultant

Scientist: The Role of the Placenta in Gestational Diabetes & Preeclampsia, published in high impact peer reviewed journals, won awards for research (Fulbright Distinguished Scholar Award, Churchill Fellowship)

My Role in The CRN: To Facilitate Research within the Thames Valley & South Midlands.

A Little About Me….

Why do research at all?Constitutional: NHS constitution “Research is a core part of the NHS. Research

enables the NHS to improve the current and future health of the people it serves”.

NHS Operating Framework: “All providers must increase participation in research”

Financial: Significant income opportunities. Every £1 invested in research yields annual rate of return 39% (RAND 2007). Best value healthcare

Better clinical services - patient care improved, clinicians motivated, patient experience improved, culture of inquiry.

Prestige. World Class University, forefront of innovation. World leading researchers.

Moral imperative: To advance knowledge to improve patient care.

NHS Innovation Landscape

• Biomedical Research Centres and Units

• Collaborations in Leadership and Applied Health Research and Care

• Clinical Research Networks

• Clinical Research Facilities

Academic Health Science Centres

Academic Health Science Networks

‘Test bed’ sites

(Health Innovation Education ClusterNHS Innovations hub)

Aims

UK best in the world for

• Health Research

• Development

• Innovation

What has changed

From

• 9 Coordinating Centres

• 102 Local Networks

• Inconsistent coverage with complex geography

To

• 1 Coordinating Centre

• 15 Local Networks

• Simplified national coverage across all therapy areas

Clinical Research Networks

Thames Valley and South Midlands

Host Trust CEO

Sir Jonathan Michael

Host Trust Executive

Dr Anthony Berendt

LCRN Clinical Directors

Dr Belinda Lennox ,

Dr Andrew Protheroe

Divisional

Research Leads

x6 (I’m in this

group)

Chief Operating Officer

Val Woods

Research Delivery

Managers x6 (Tessa

John in this group)

Cross divisional team

Specialty Leads x30

Who?

30 specialties, 6 delivery divisions

1. Cancer

2. Diabetes, metabolic & endocrine disorders, renal disorders

3. Stroke, cardiovascular disease

4. Children

5. Genetics, haematology, reproductive health & childbirth

6. Dementias and neurodegeneration (DeNDRoN), neurological disorders

7. Mental health

8. Primary care, ageing, health services & research delivery, oral & dental health, public health

9. Musculoskeletal, dermatology

10. Anaesthesia, peri-operative medicine & pain management, critical care, injuries & emergencies, surgery

11. Ear nose & throat, infectious diseases & microbiology, ophthalmology, respiratory disorders

12. Gastroenterology, hepatology

What do Research Networks provide?

• Provide infrastructure needed to do clinical research

• Recognize and reward research as part of the “core business” of a Trust and its workforce

• Facilitate networks of research-active clinicians

• Decrease or alleviate bureaucracy burden

• Deal with systemic blocks to research delivery

What does that mean for us?

• Budget of £13.5m for 2014/15

• Approximately 400 research nurses,doctors, administrators and supportworkers delivering research across theregion

• Activity based funding

Only 1 criterion for support:

Doing research on the CRN portfolio

(Funding)

Can we help you?

• Find new studies

• Get started as a PI

• Flexible support as required

• Commercial trial support

National High Level Objectives:

86

586

84

2,171

56

8,513

62

1,366

59

2,774

72

1,717

0

1000

2000

3000

4000

5000

6000

7000

8000

9000

Div 1 Div 2 Div 3 Div 4 Div 5 Div 6

CRN: TV&SM no. of studies and recruitment by division

National Committee for Reproductive Health

• New Studies introduced and local PIs identified

• Key priorities for Reproductive Health fed back to funding bodies especially NIHR

• Commercial studies a major target

Three Diseases in Obsetrics• Three commercial opportunities for TV & SM

– Preeclampsia – Roche Diagnostics

– Preterm Labour – GSK

– Gestational Diabetes – Lilly

– Together the sum of the parts is greater than the whole

How can we help?

• Manu.Vatish@obs-gyn.ox.ac.uk

• Tessa.John@ouh.nhs.uk

• Fiona.Goddard@obs-gyn.ox.ac.uk