Composition, Structure, Modelling and Remodelling of Bones

Clara Amanda Schram11.2014.017

Bone Composition

The matrix Bone Mineral

Bone Cells

The matrix

Collagen

Non-collagenous protein:- Proteoglycans

-Osteonectin-Osteocalcin

Bone mineral

Calcium

Phosphate

BONE CELLS

OSTEOBLAST

FOR OSTEOGENESI

S OR OSSIFICATION

OSTEOCYTES

MATURE BONE CELLS

OSTEOCLAST

RESORBING OR REMOVING

BONE

Bone Structure

STUCTURE OF BONE

GROSS STRUCTURE

COMPACTA SPONGIOSA

HISTOLOGIC STRUCTURES

MATURE BONE ( LAMELLAR

BONE )

IMMATURE BONE ( WOVEN BONE )

Bone Modelling and Remodelling

Membranous ossification

Endochondral ossification

Bone Modelling

Mineral exchange

PhosphorusCalcium

Vitamin D Magnesium

CalcitoninPTH

Calcium and Phosphorus Metabolism

The normal plasma level of both calcium and inorganic phosphate are regulated by three hormones :

• The active metabolics of vitamin D• Parathyroid hormone (PTH)• Calcitonin

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