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Loss of hydrogen atoms
Glucose
Gain of hydrogen atoms
Energy
8.1.1 Comparison of Oxidation and Reduction
Oxidation: often associated with the release of energy
Reduction: often associated with the gain of energy
8.1.1 Comparison of Oxidation and Reduction
Reduction and Oxidation Reaction: Electron carriers
• Electron carriers are substances that accept and give up electrons as required.
• They often link oxidations and reductions in cells.
• Main electron carrier is NAD (nicotinamide adenine dinucleotide), it is a coenzyme
• It’s Reduced to NADH when it picks up two electrons and one hydrogen ion
NAD+ + 2 H NADH + H+
FAD + 2 H FADH2
Remember that 2H = 2 electrons and 2H+
Aerobic respiration process
Glucose (6C)
Glucose phosphate (6C)
Fructose bisphosphate (6C)
glicerate 3-phosphate (3C)
glicerate 3-phosphate (3C)
Pyruvate (3C) Pyruvate (3C)
ATP
ADP + Pi
ATP
ADP + Pi
2 ADP + Pi
2 ADP + Pi
2 ATP 2 ATP
NAD+
NADH + H +
NAD+
NADH + H +
8.1.2 Outline the process of Glycolysis
PHOSPORILATION
LYSIS
OXIDATION&
ATP FORMATION
8.1.3 Structure mitochondrion like in micrographs
8.1.4 Aerobic respiration: the link reaction
Acetyl Coenzyme A(2C)
Coenzyme A
Piruvate (3C)
Acetate (2C)
+
CO2
NAD+
NADH + H +
Piruvate (3C) enters the matrix of the mitochondria from the cytoplasm
Piruvate + CoA +NAD+ acetyl-CoA + CO2 +NADH + H+
8.1.4 Aerobic respiration: Krebs Cycle
1. Acetyl Co-A combines with a 4-
carbon compound (oxalacetate)
to form a six-carbon compound
(citrate)
2. A series of reactions take place
where the citrate (6C) is both
decarboxylated and
dehydrogenated
3. The most important role of the
Krebs cycle is to provide
hydrogen that can be used in
the electron transport chain to
provide energy for the
formation of ATP.
8.1.4 Aerobic respiration: The electron transport chain
The final stage occurs in the inner membranes of mitochondria. This stage has two parts: an electron transport chain and ATP production by ATP synthase
8.1.5 Electron Transport Chain & Oxidative phosphorilation
Chemiosmosis couples the electron transport chain to ATP synthesis
8.1.5 Oxidative phosphorilation & Chemiosmotic theory
8.1.6 Relationship between structure of mitochondrion and its function
1. Cristae: Large Surface Area for the Electron Transport Chain
2. Intermembrane Space: Accumulation of protons
3. Matrix: containing enzymes for the Krebs Cycle
Overview Aerobic Cell Respiration
ATP balance