Lecture 3 Motor

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    Lecture 3 Sensory/Motor

    MOTOR SYSTEMS

    1. Components of Motor Systems

    muscles, spinal cord, brain stem, motor cortex,premotor and supplemental areas of the cortex,

    cerebellum and basal ganglia

    Serial (hierarchical) organization

    parallel organization

    2. Muscles: controlled by nerves

    A. General structure

    A skeletal muscle is made up of muscle cells(muscle fibers)

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    Supplementalarea

    BasalgangliaCerebellum

    Premotor

    cortex

    Thalamus

    Motor

    cortex

    Brainstem

    Gammamotor

    neuron

    Interneuron

    Golgitendonorgan

    Musclespindle

    Alphamotorneuron

    Muscle

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    Multinucleate

    extrafusal fibers and intrafusal fibers

    B. Types and actions of skeletal muscle

    muscle tendons

    flexor extensor

    synergistic and antagonistic

    fast skeletal muscle slow skeletal muscle

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    3. Motor neurons

    A. E motor neuron

    large diameter with axons of 12-20 Qmdiameter

    innervating extrafusal fibers neuromuscular junctions

    neurotransmitter: acetylcholine

    receptor: nicotinic receptorsB. K motor neuron

    small cells with axons of 1-8 Qm diameter

    innervating intrafusal fibers

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    4. Motor units

    an individual motor neuron + all the musclefibers

    small motor unit controls very fine movements

    large motor unit responsible for grossmovements

    frequency code of contractile force

    population code of contractile force

    5. The Spinal Cord in the Motor Response System

    A. Interneurons

    located dorsally at the base of the ventral horn

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    receive inputs from sensory nerves and othermotor centers

    act locally with the same spinal segment or

    some send information to other spinal levels.

    excitatory interneurons are associated with theactivation of synergistic muscles

    inhibitory interneurons are associated with

    suppressing the activation of antagonisticmuscles

    B. Locomotor generators control walking movement

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    C. Regulation of motor neuron activity by sensorysignals

    muscle spindle (stretch receptor)

    sensory neurons + intrafusal fibers

    detect the length of the muscle and also

    velocity of muscle contraction

    innervated by gamma fibers, which regulate

    the sensitivity of sensory nerves of themuscle spindles

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    Golgi tendon organs transmit information about the force or

    tension produced by the contraction of

    the muscle

    spinal cord reflexes stretch reflex

    inverse myotatic reflex

    flexor withdrawal reflex

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    Stretch reflex

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    Inverse myotatic reflex

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    Flexor withdrawal reflex

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    6. The Brain in the Motor Response System

    A. The brain stem controls posture

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    B. The motor cortex control reaching and fine

    voluntary movements cells in the motor cortex are organized in a

    somatotopic manner similar to that of the somatic

    sensory cortex

    pyramidal tract majority of fibers cross the midline of the body

    C. The cerebellum: planning, coordination, and

    postureD. The basal ganglia: planning of movement and

    inhibition of motor tone

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    7. Disorders of the Motor System

    A. Lesions of the pyramidal tract: paralysis

    upper-motor-neuron lesions

    paralysis on the side of the body opposite the

    side of the lesion increase in muscle tone

    hyperactive reflexes

    Babinski sign

    lesions within the spinal cord

    changes occur ipsilaterally

    loss of strength

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    loss of movement in muscle groups

    loss of voluntary contracting force

    Babinski sign

    lower-motor-neuron lesions (spinal cord injuries)

    injuries to the motor neurons rather than their

    inputs

    ipslateral hypoactive reflexes

    paralysis to specific groups of muscles

    flaccid muscles with prominent atrophy

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    B. Lesions of the cerebellum

    ipsilateral disturbancesl lack of limb coordination

    Ataxia

    action tremor