Kit Summary - Antibodies, Proteins, Kits and Reagents for … · 2015-09-02 · Proclin - 55965-84-9 0.0015 T; R20/21/22 C; R34 R43 N; R50-53 ... (300 pg/mL) Chemical Name EC-No CAS-No

Kit Summary

Product Code(s) AB108667Product name 17 beta Estradiol ELISA Kit

Stop Solution

Chemical Name EC-No CAS-No Weight % Classification(67/548)

Classification(Reg. 1272/2008)

REACHRegistration

NumberSulphuric acid 231-639-5 7664-93-9 1.5 C; R35 Skin Corr. 1A

(H314)no data available

17 beta Estradiol-HRP Conjugate



REACHRegistration

NumberProclin - 55965-84-9 0.010 T; R20/21/22

C; R34R43

N; R50-53

Skin Corr. 1B(H314)

Skin Sens. 1(H317)

Aquatic Acute 1(H400)

Aquatic Chronic 1(H410)

no data available

TMB Substrate Solution



REACHRegistration

NumberDMSO 200-664-3 67-68-5 5 -

TMB 259-364-6 54827-17-7 0.03 Xi; R36/37/38 STOT SE 3 (H335) Skin Irrit. 2 (H315) Eye Irrit. 2 (H319)

Hydrogen peroxide 231-765-0 7722-84-1 0.0015 Xn; R20/22

C; R35

Xi; R41R5

O; R8

Acute Tox. 4(H302)

Acute Tox. 4(H332)

Skin Corr. 1A(H314)

Eye Dam. 1(H318)

17 beta Estradiol Standard 0



REACHRegistration

NumberSodium EDTA 200-573-9 64-02-8 0.46 Xn;R22

Xi;R41Eye Dam. 1 (H318)

Acute Tox. 4(H302)

Proclin - 55965-84-9 0.0015 T; R20/21/22C; R34

R43N; R50-53

Skin Corr. 1B(H314)

Skin Sens. 1(H317)



17 beta Estradiol Control



REACHRegistration



Acute Tox. 4(H302)

no data available

Proclin - 55965-84-9 0.0015 T; R20/21/22C; R34

R43N; R50-53

Skin Corr. 1B(H314)

Skin Sens. 1(H317)



no data available

17 beta Estradiol Standard 1 (20 pg/mL)



REACHRegistration



Acute Tox. 4(H302)

no data available

Proclin - 55965-84-9 0.0015 T; R20/21/22C; R34

R43N; R50-53

Skin Corr. 1B(H314)

Skin Sens. 1(H317)



no data available




REACHRegistration



Acute Tox. 4(H302)

Proclin - 55965-84-9 0.0015 T; R20/21/22C; R34

R43N; R50-53

Skin Corr. 1B(H314)

Skin Sens. 1(H317)






REACHRegistration



Acute Tox. 4(H302)

Proclin - 55965-84-9 0.0015 T; R20/21/22C; R34

R43N; R50-53

Skin Corr. 1B(H314)

Skin Sens. 1(H317)






REACHRegistration



Acute Tox. 4(H302)

no data available

Proclin - 55965-84-9 0.0015 T; R20/21/22C; R34

R43N; R50-53

Skin Corr. 1B(H314)

Skin Sens. 1(H317)



no data available

17 beta Estradiol Standard 5 (2,000 pg/mL)



REACHRegistration



Acute Tox. 4(H302)

Proclin - 55965-84-9 0.0015 T; R20/21/22C; R34

R43N; R50-53

Skin Corr. 1B(H314)

Skin Sens. 1(H317)



GHS / CLP - GHS - Classification

Signal WordWarning

Hazard statementsH317 - May cause an allergic skin reaction

Precautionary Statements - EU (§28, 1272/2008)P302 + P352 - IF ON SKIN: Wash with plenty of soap and waterP333 + P313 - If skin irritation or rash occurs: Get medical advice/ attentionP280 - Wear protective gloves/ eye protection/ face protectionP261 - Avoid breathing dust/ fume/ gas/ mist/ vapors/ sprayP272 - Contaminated work clothing should not be allowed out of the workplaceP363 - Wash contaminated clothing before reuseP501 - Dispose of contents/ container to an approved waste disposal plant

2.3 Other information

A safety datasheet follows for all potentially hazardous components – all other components are non-hazardousAvoid contact with DMSO solutions containing toxic materials or materials with unknown toxicological properties. DMSO is readilyabsorbed through skin and may carry such materials into the body.

TRANSPORT INFORMATION

DOT Not dangerous goods

IATA Not dangerous goods

ADR Not dangerous goods

Revision Date 02-Sep-2015 Version 8

Safety Data SheetIssuing date no data available

For research use only

Ozone Not applicable

E-mail address [email protected]

GHS Label elements, including precautionary statements

Product name 17 beta Estradiol Control

Emergency telephone Tel: (617)225-2272 or 888-77-ABCAM (22226) (US toll free) - Monday-Friday 8am-9pmEST

Signal WordWarning


1. PRODUCT AND COMPANY IDENTIFICATION

2. HAZARDS IDENTIFICATION

Precautionary Statements - EU (§28, 1272/2008)P302 + P352 - IF ON SKIN: Wash with plenty of soap and waterP333 + P313 - If skin irritation or rash occurs: Get medical advice/ attentionP261 - Avoid breathing dust/ fume/ gas/ mist/ vapors/ sprayP280 - Wear protective gloves/ eye protection/ face protectionP272 - Contaminated work clothing should not be allowed out of the workplaceP363 - Wash contaminated clothing before reuseP501 - Dispose of contents/ container to an approved waste disposal plant

GHS - Classification

Recommended use

Other information

Skin sensitization Category 1

Supplier Address Abcam Inc1 Kendall Square, Ste 341Cambridge, MA 02139-1517USATel: (617)225-2272 or 888-77-ABCAM (22226) (US toll free)Fax: (866) 739-9884 or (866) 457-9616 (both US toll free)

_____________________________________________________________________________________________AB108667-CP147578 - 17 beta Estradiol Control Revision Date 02-Sep-2015

Explosion Data Sensitivity to Mechanical Impact none.

Flammable properties Not flammable.

Sensitivity to Static Discharge none.

No information available

Specific hazards arising from thechemical

Thermal decomposition can lead to release of irritating gases and vapors In the event of fireand/or explosion do not breathe fumes May cause sensitization by inhalation and skincontact

Flash point not determined

Protective equipment andprecautions for firefighters

As in any fire, wear self-contained breathing apparatus pressure-demand, MSHA/NIOSH(approved or equivalent) and full protective gear.

5. FIRE-FIGHTING MEASURES

Suitable extinguishing media Use extinguishing measures that are appropriate to local circumstances and thesurrounding environment.

Move to fresh air.

3. COMPOSITION/INFORMATION ON INGREDIENTS

Sodium EDTA 64-02-8 0.1-1

Ingestion Clean mouth with water. Drink plenty of water.

Eye Dam. 1 (H318) Acute Tox. 4 (H302)

4. FIRST AID MEASURES

Notes to physician May cause sensitization of susceptible persons. Treat symptomatically.

Proclin 55965-84-9 <0.1 Skin Corr. 1B (H314) Skin Sens. 1 (H317)

Aquatic Acute 1 (H400)Aquatic Chronic 1 (H410)

General advice If symptoms persist, call a physician.

Eye contact Immediately flush with plenty of water. After initial flushing, remove any contact lenses andcontinue flushing for at least 15 minutes.

Chemical Name CAS-No

For the full text of the H-Statements mentioned in this Section, see Section 16

Weight %

_____________________________________________________________________________________________

Skin contact Wash off immediately with soap and plenty of water while removing all contaminatedclothes and shoes. May cause an allergic skin reaction. If symptoms persist, call aphysician.

Classification (Reg. 1272/2008)

Page 6 / 64

3.1 Substances

Inhalation


7. HANDLING AND STORAGE

Advice on safe handling Ensure adequate ventilation. Wear personal protective equipment.

Technical measures/Storageconditions

Keep out of the reach of children. Keep container tightly closed. Keep containers tightlyclosed in a cool, well-ventilated place.

Personal precautions

Engineering measures ShowersEyewash stationsVentilation systems

9. PHYSICAL AND CHEMICAL PROPERTIES

Environmental precautions Try to prevent the material from entering drains or water courses.

Methods for cleaning up

Personal protective equipment

Soak up with inert absorbent material. Pick up and transfer to properly labeled containers.After cleaning, flush away traces with water. Prevent product from entering drains.

Use personal protective equipment. Avoid contact with the skin and the eyes.

Eye/face protection Tightly fitting safety goggles.

8. EXPOSURE CONTROLS/PERSONAL PROTECTION

Skin and body protection No special protective equipment required.Respiratory protection If exposure limits are exceeded or irritation is experienced, NIOSH/MSHA approved

respiratory protection should be worn. Positive-pressure supplied air respirators may berequired for high airborne contaminant concentrations. Respiratory protection must beprovided in accordance with current local regulations.

6. ACCIDENTAL RELEASE MEASURES

Hygiene measures When using, do not eat, drink or smoke. Remove and wash contaminated clothing beforere-use.

Exposure Guidelines This product does not contain any hazardous materials with occupational exposure limitsestablished by the region specific regulatory bodies.

Methods for containment Prevent further leakage or spillage if safe to do so.

Boiling point/boiling range

Evaporation rate No information available

No information availableNo information available

pH No information available

Vapor density no data available

Odor

Melting point/range No information available

VOC Content(%) not applicable

No information available.

Autoignition temperature No information available

Physical State @20°C No information availableOdor Threshold

Specific Gravity no data available

Decomposition temperature No information available

No information availableAppearance

solubility

_____________________________________________________________________________________________



Flash point

Page 7 / 64

Flammability Limits in AirExplosion limits No information available



14. TRANSPORT INFORMATION

Stability

Chemical Name LD50 Oral

12. ECOLOGICAL INFORMATION

LD50 Dermal LC50 Inhalation

Incompatible products

Ecotoxicity

Sodium EDTA 10 g/kg ( Rat )

The environmental impact of this product has not been fully investigated.

None known based on information supplied.

11. TOXICOLOGICAL INFORMATION

Chemical Name Toxicity to algae Toxicity to fish Toxicity tomicroorganisms

Toxicity to daphnia andother aquatic invertebrates

Proclin 53 mg/kg ( Rat )

Sodium EDTA 1.01: 72 h Desmodesmussubspicatus mg/L EC50

41: 96 h Lepomismacrochirus mg/L LC50

static 59.8: 96 h Pimephalespromelas mg/L LC50 static

610: 24 h Daphnia magnamg/L EC50

Hazardous decomposition products None known based on information supplied.

Chronic toxicity

13. DISPOSAL CONSIDERATIONS

Stable under recommended storage conditions.

Waste disposal methods This material, as supplied, is not a hazardous waste according to Federal regulations (40CFR 261). This material could become a hazardous waste if it is mixed with or otherwisecomes in contact with a hazardous waste, if chemical additions are made to this material, orif the material is processed or otherwise altered. Consult 40 CFR 261 to determine whetherthe altered material is a hazardous waste. Consult the appropriate state, regional, or localregulations for additional requirements.

Chronic toxicity Repeated contact may cause allergic reactions in very susceptible persons Avoid repeatedexposure

Acute toxicity

Contaminated packaging Do not re-use empty containers.

10. STABILITY AND REACTIVITY

Sensitization As a precaution the product should be treated as a sensitizer.

Hazardous polymerization

Product Information May cause sensitization of susceptible persons.

Hazardous polymerization does not occur.

_____________________________________________________________________________________________

Target Organ Effects None known.

Page 8 / 64

Conditions to avoid None known based on information supplied.


Clean Water ActThis product does not contain any substances regulated as pollutants pursuant to the Clean Water Act (40 CFR 122.21 and 40CFR 122.42).

SARA 313Section 313 of Title III of the Superfund Amendments and Reauthorization Act of 1986 (SARA). This product does not contain anychemicals which are subject to the reporting requirements of the Act and Title 40 of the Code of Federal Regulations, Part 372.

CERCLAThis material, as supplied, does not contain any substances regulated as hazardous substances under the ComprehensiveEnvironmental Response Compensation and Liability Act (CERCLA) (40 CFR 302) or the Superfund Amendments andReauthorization Act (SARA) (40 CFR 355). There may be specific reporting requirements at the local, regional, or state levelpertaining to releases of this material.


U.S. State Regulations

SARA 311/312 Hazard Categories

California Proposition 65This product does not contain any Proposition 65 chemicals.

Acute Health Hazard yes

U.S. State Right-to-Know Regulations

International Regulations

Chronic Health Hazard no

15. REGULATORY INFORMATION

Fire Hazard

WHMIS Note: This product has been classified in accordance with the hazard criteria of theControlled Products Regulations (CPR) and the MSDS contains all the informationrequired by the CPR.

no


Sudden Release of Pressure Hazard no

U.S. Federal Regulations

_____________________________________________________________________________________________

Reactive Hazard no

Page 9 / 64



End of MSDS

Revision Note No information available.

Full text of H-Statements referred to under sections 2 and 3H314 - Causes severe skin burns and eye damage H317 - May cause an allergic skin reaction H400 - Very toxic to aquatic lifeH410 - Very toxic to aquatic life with long lasting effects


_____________________________________________________________________________________________

DisclaimerThe information provided in this Safety Data Sheet is correct to the best of our knowledge, information and belief at the date of itspublication. The information given is designed only as a guidance for safe handling, use, processing, storage, transportation, disposaland release and is not to be considered a warranty or quality specification. The information relates only to the specific materialdesignated and may not be valid for such material used in combination with any other materials or in any process, unless specified in thetext.

16. OTHER INFORMATION

Revision Date

Page 10 / 64

02-Sep-2015







Product name 17 beta Estradiol Standard 1 (20 pg/mL)


Signal WordWarning




Precautionary Statements - EU (§28, 1272/2008)P302 + P352 - IF ON SKIN: Wash with plenty of soap and waterP261 - Avoid breathing dust/ fume/ gas/ mist/ vapors/ sprayP272 - Contaminated work clothing should not be allowed out of the workplaceP280 - Wear protective gloves/ eye protection/ face protectionP333 + P313 - If skin irritation or rash occurs: Get medical advice/ attentionP363 - Wash contaminated clothing before reuseP501 - Dispose of contents/ container to an approved waste disposal plant


Recommended use

Other information



_____________________________________________________________________________________________AB108667-CP173216 - 17 beta Estradiol Standard 1 (20 pg/mL) Revision Date 02-Sep-2015












Move to fresh air.













Weight %

_____________________________________________________________________________________________



Page 12 / 64

3.1 Substances

Inhalation



























Odor









solubility

_____________________________________________________________________________________________



Flash point

Page 13 / 64





Stability





Ecotoxicity













Chronic toxicity





Acute toxicity







_____________________________________________________________________________________________


Page 14 / 64















Fire Hazard


no




_____________________________________________________________________________________________

Reactive Hazard no

Page 15 / 64



End of MSDS




_____________________________________________________________________________________________



Revision Date

Page 16 / 64

02-Sep-2015









Signal WordWarning






Recommended use

Other information















Move to fresh air.













Weight %

_____________________________________________________________________________________________



Page 18 / 64

3.1 Substances

Inhalation



























Odor









solubility

_____________________________________________________________________________________________



Flash point

Page 19 / 64





Stability





Ecotoxicity













Chronic toxicity





Acute toxicity







_____________________________________________________________________________________________


Page 20 / 64















Fire Hazard


no




_____________________________________________________________________________________________

Reactive Hazard no

Page 21 / 64



End of MSDS




_____________________________________________________________________________________________



Revision Date

Page 22 / 64

02-Sep-2015









Signal WordWarning






Recommended use

Other information















Move to fresh air.













Weight %

_____________________________________________________________________________________________



Page 24 / 64

3.1 Substances

Inhalation



























Odor









solubility

_____________________________________________________________________________________________



Flash point

Page 25 / 64





Stability





Ecotoxicity













Chronic toxicity





Acute toxicity







_____________________________________________________________________________________________


Page 26 / 64















Fire Hazard


no




_____________________________________________________________________________________________

Reactive Hazard no

Page 27 / 64



End of MSDS




_____________________________________________________________________________________________



Revision Date

Page 28 / 64

02-Sep-2015









Signal WordWarning






Recommended use

Other information















Move to fresh air.













Weight %

_____________________________________________________________________________________________



Page 30 / 64

3.1 Substances

Inhalation



























Odor









solubility

_____________________________________________________________________________________________



Flash point

Page 31 / 64





Stability





Ecotoxicity













Chronic toxicity





Acute toxicity







_____________________________________________________________________________________________


Page 32 / 64















Fire Hazard


no




_____________________________________________________________________________________________

Reactive Hazard no

Page 33 / 64



End of MSDS




_____________________________________________________________________________________________



Revision Date

Page 34 / 64

02-Sep-2015







Product name 17 beta Estradiol Standard 5 (2,000 pg/mL)


Signal WordWarning






Recommended use

Other information



_____________________________________________________________________________________________AB108667-CP173220 - 17 beta Estradiol Standard 5 (2,000 pg/mL) Revision Date 02-Sep-2015












Move to fresh air.













Weight %

_____________________________________________________________________________________________



Page 36 / 64

3.1 Substances

Inhalation



























Odor









solubility

_____________________________________________________________________________________________



Flash point

Page 37 / 64





Stability





Ecotoxicity













Chronic toxicity





Acute toxicity







_____________________________________________________________________________________________


Page 38 / 64















Fire Hazard


no




_____________________________________________________________________________________________

Reactive Hazard no

Page 39 / 64



End of MSDS




_____________________________________________________________________________________________



Revision Date

Page 40 / 64

02-Sep-2015



Tel: (617)225-2272 or 888-77-ABCAM (22226) (US toll free) - Monday-Friday 8am-9pmEST

Other information



2. HAZARDS IDENTIFICATIONGHS - Classification

Recommended use





Product name Stop Solution

Emergency telephone

Skin Corr. 1A (H314)


Supplier Address


3.1 Substances

Abcam Inc1 Kendall Square, Ste 341Cambridge, MA 02139-1517USATel: (617)225-2272 or 888-77-ABCAM (22226) (US toll free)Fax: (866) 739-9884 or (866) 457-9616 (both US toll free)

Chemical Name CAS-No Weight % Classification (Reg. 1272/2008)Sulphuric acid 7664-93-9 1-5

_____________________________________________________________________________________________AB108667-CP91791 - Stop Solution Revision Date 02-Sep-2015




Advice on safe handling Handle in accordance with good industrial hygiene and safety practice.

Explosion Data



Keep containers tightly closed in a dry, cool and well-ventilated place.

Sensitivity to Mechanical Impact none.

Flammable properties


Not flammable.



Personal precautions Ensure adequate ventilation.

Skin contact


Wash off immediately with soap and plenty of water while removing all contaminatedclothes and shoes.




Notes to physician Treat symptomatically.


_____________________________________________________________________________________________

Pick up and transfer to properly labeled containers.

Inhalation

Page 42 / 64

Move to fresh air.




Exposure Guidelines

Respiratory protection If exposure limits are exceeded or irritation is experienced, NIOSH/MSHA approvedrespiratory protection should be worn. Positive-pressure supplied air respirators may berequired for high airborne contaminant concentrations. Respiratory protection must beprovided in accordance with current local regulations.

Chemical Name ACGIH TLV

Other Exposure Guidelines Vacated limits revoked by the Court of Appeals decision in AFL-CIO v. OSHA, 965 F.2d962 (11th Cir., 1992).

Hygiene measures Handle in accordance with good industrial hygiene and safety practice.

OSHA PEL NIOSH IDLH


This product does not contain any hazardous materials with occupational exposure limitsestablished by the region specific regulatory bodies.

Stability Stable under recommended storage conditions.


Sulphuric acid 7664-93-9

TWA: 0.2 mg/m3 thoracic fraction

Incompatible products None known based on information supplied.



TWA: 1 mg/m3

(vacated) TWA: 1 mg/m3

IDLH: 15 mg/m3

TWA: 1 mg/m3



Hazardous polymerization Hazardous polymerization does not occur.


Eye/face protection No special protective equipment required.

NIOSH IDLH: Immediately Dangerous to Life or Health

Skin and body protection No special protective equipment required.

Odor









solubility No information available.


Flash pointBoiling point/boiling range



pH

_____________________________________________________________________________________________



Page 43 / 64

Explosion limits No information availableNo information availableFlammability Limits in Air



LD50 Dermal

Sulphuric acid A2 Group 1



Known X

Sulphuric acid 500: 96 h Brachydanio reriomg/L LC50 static


LC50 Inhalation

Product Information

ACGIH: (American Conference of Governmental Industrial Hygienists)A2 - Suspected Human Carcinogen

Product does not present an acute toxicity hazard based on known or supplied information.

Sulphuric acid

IARC: (International Agency for Research on Cancer)Group 1 - Carcinogenic to Humans


2140 mg/kg ( Rat )

NTP: (National Toxicity Program)Known - Known Carcinogen


510 mg/m3 ( Rat ) 2 h 347 ppm (Rat ) 1 h

OSHA: (Occupational Safety & Health Administration)X - Present


Chronic toxicity

This product contains one or more substances that are listed with the State of California as a hazardous waste.


Chemical Name California Hazardous Waste Status

Target Organ Effects

Sulphuric acid Toxic Corrosive

Eyes. Respiratory system. Skin. Teeth.

Carcinogenicity This product contains one or more substances which are classified by IARC ascarcinogenic to humans (Group I), probably carcinogenic to humans (Group 2A) or possiblycarcinogenic to humans (Group 2B)

Acute toxicity

Chemical Name


Chemical Name ACGIH

_____________________________________________________________________________________________

IARC NTP

Ecotoxicity

Page 44 / 64

OSHA

LD50 Oral



CWA - ReportableQuantities

CWA - Toxic Pollutants CWA - Priority Pollutants CWA - HazardousSubstances

Weight % SARA 313 - ThresholdValues %

Sulphuric acid 1000 lb X

IATA


Sulphuric acid 7664-93-9 1.5 1.0

Chemical Name Hazardous Substances RQs Extremely Hazardous SubstancesRQs

RQ

Not dangerous goods


Sulphuric acid 1000 lb 1000 lb RQ 1000 lb final RQ RQ 454 kg finalRQ



Acute Health Hazard

California Proposition 65This product contains the following Proposition 65 chemicals:

no


Chemical Name CAS-No California Prop. 65


Sulphuric acid 7664-93-9 Carcinogen


Fire Hazard

Chemical Name Massachusetts New Jersey Pennsylvania Illinois Rhode Island

no

Sulphuric acid X X X X X



SARA 313Section 313 of Title III of the Superfund Amendments and Reauthorization Act of 1986 (SARA). This product contains a chemicalor chemicals which are subject to the reporting requirements of the Act and Title 40 of the Code of Federal Regulations, Part 372:

Chemical Name Carcinogen Status Exposure limits

Reactive Hazard

Sulphuric acid A2 Mexico: TWA 1 mg/m3

no


_____________________________________________________________________________________________



Page 45 / 64


Chemical Name




Full text of H-Statements referred to under sections 2 and 3H314 - Causes severe skin burns and eye damage

_____________________________________________________________________________________________


Revision Date 02-Sep-2015

Page 46 / 64


End of MSDS







Product name 17 beta Estradiol-HRP Conjugate


Signal WordWarning






Recommended use

Other information



_____________________________________________________________________________________________AB108667-CP91839 - 17 beta Estradiol-HRP Conjugate Revision Date 02-Sep-2015












Explosion Data




Chemical Name


CAS-No Weight %



3.1 Substances


Proclin

Inhalation Move to fresh air.

55965-84-9 <0.1

_____________________________________________________________________________________________

Skin Corr. 1B (H314) Skin Sens. 1 (H317)



Ingestion

Page 48 / 64

Clean mouth with water. Drink plenty of water.



























Odor









solubility

_____________________________________________________________________________________________



Flash point

Page 49 / 64



_____________________________________________________________________________________________Revision Date 02-Sep-2015AB108667-CP91839 - 17 beta Estradiol-HRP Conjugate




Chronic toxicity







Acute toxicity




Product Information


May cause sensitization of susceptible persons.



Stability


Chemical Name LD50 Oral LD50 Dermal LC50 Inhalation

Ecotoxicity


_____________________________________________________________________________________________



Page 50 / 64




no



Fire Hazard


no




Not dangerous goods


Reactive Hazard no




Acute Health Hazard

_____________________________________________________________________________________________

yes

ADR


Page 51 / 64


Chronic Health Hazard


End of MSDS




_____________________________________________________________________________________________



Revision Date

Page 52 / 64

02-Sep-2015







Not dangerous

Product name TMB Substrate Solution


Other information



Avoid contact with DMSO solutions containing toxic materials or materials with unknown toxicological properties. DMSO is readilyabsorbed through skin and may carry such materials into the body.


Recommended use


_____________________________________________________________________________________________Revision Date 02-Sep-2015AB108667-CP91840 - TMB Substrate Solution






Flammable properties


Not flammable.


Explosion Data



Weight % Classification (Reg. 1272/2008)


3.1 Substances



DMSO

Notes to physician Treat symptomatically.

67-68-5 3-7

TMB 54827-17-7


<0.1 STOT SE 3 (H335) Skin Irrit. 2 (H315) Eye Irrit. 2 (H319)

Eye contact

_____________________________________________________________________________________________

Immediately flush with plenty of water. After initial flushing, remove any contact lenses andcontinue flushing for at least 15 minutes.

Hydrogen peroxide 7722-84-1

Page 54 / 64

<0.1 Acute Tox. 4 (H302) Acute Tox. 4 (H332)Skin Corr. 1A (H314) Eye Dam. 1 (H318)

Skin contact Wash off immediately with soap and plenty of water while removing all contaminatedclothes and shoes.

_____________________________________________________________________________________________Revision Date 02-Sep-2015AB108667-CP91840 - TMB Substrate Solution

Advice on safe handling Handle in accordance with good industrial hygiene and safety practice.



Keep containers tightly closed in a dry, cool and well-ventilated place.






Eye/face protection No special protective equipment required.Skin and body protection No special protective equipment required.


Chemical Name

Respiratory protection If exposure limits are exceeded or irritation is experienced, NIOSH/MSHA approvedrespiratory protection should be worn. Positive-pressure supplied air respirators may berequired for high airborne contaminant concentrations. Respiratory protection must beprovided in accordance with current local regulations.

ACGIH TLV OSHA PEL NIOSH IDLH

Hygiene measures Handle in accordance with good industrial hygiene and safety practice.

Environmental precautions

Hydrogen peroxide 7722-84-1

TWA: 1 ppm TWA: 1 ppm TWA: 1.4 mg/m3

(vacated) TWA: 1 ppm (vacated)TWA: 1.4 mg/m3

IDLH: 75 ppmTWA: 1 ppm TWA: 1.4 mg/m3

Try to prevent the material from entering drains or water courses.


NIOSH IDLH: Immediately Dangerous to Life or Health

Pick up and transfer to properly labeled containers.

Ensure adequate ventilation.

_____________________________________________________________________________________________


Other Exposure Guidelines Vacated limits revoked by the Court of Appeals decision in AFL-CIO v. OSHA, 965 F.2d962 (11th Cir., 1992).

Page 55 / 64

_____________________________________________________________________________________________AB108667-CP91840 - TMB Substrate Solution Revision Date 02-Sep-2015

Product Information Product does not present an acute toxicity hazard based on known or supplied information.


Chemical Name LD50 Oral LD50 Dermal LC50 InhalationDMSO 14500 mg/kg ( Rat ) 40 g/kg ( Rat )

Hydrogen peroxide 801 mg/kg ( Rat ) 4060 mg/kg ( Rat ) 2000 mg/kg (Rabbit )

2 mg/L ( Rat ) 4 h


Chronic toxicity

Carcinogenicity This product contains one or more substances which are classified by IARC ascarcinogenic to humans (Group I), probably carcinogenic to humans (Group 2A) or possiblycarcinogenic to humans (Group 2B)


Chemical Name ACGIH IARC NTP OSHAHydrogen peroxide A3 Group 3






Acute toxicity


Appearance








Odor


VOC Content(%) 5




Specific Gravity

_____________________________________________________________________________________________

no data available



Page 56 / 64

No information availableNo information availableFlammability Limits in Air

Explosion limits


IATA


Not dangerous goods

SARA 311/312 Hazard Categories Acute Health Hazard no


ADR


Not dangerous goods

Fire Hazard no

DOT


Not dangerous goods

15. REGULATORY INFORMATIONU.S. Federal Regulations


34: 96 h Pimephalespromelas mg/L LC50 33-37:96 h Oncorhynchus mykiss

g/L LC50 static 40: 96 hLepomis macrochirus g/L

LC50 static 41.7: 96 hCyprinus carpio g/L LC50

7000: 24 h Daphnia speciesmg/L EC50


Ecotoxicity

Hydrogen peroxide 2.5: 72 h Chlorella vulgarismg/L EC50

16.4: 96 h Pimephalespromelas mg/L LC50 18-56:96 h Lepomis macrochirusmg/L LC50 static 10.0-32.0:96 h Oncorhynchus mykiss

mg/L LC50 static


7.7: 24 h Daphnia magnamg/L EC50 18 - 32: 48 h

Daphnia magna mg/L EC50Static

This product contains one or more substances that are listed with the State of California as a hazardous waste.

Chemical Name log Pow

Chemical Name

Chemical Name California Hazardous Waste Status

DMSO -2.03

Hydrogen peroxide Toxic Corrosive Ignitable Reactive

_____________________________________________________________________________________________

Toxicity to algae Toxicity to fish Toxicity tomicroorganisms


Page 57 / 64



DMSO 12350 - 25500: 96 hSkeletonema costatum mg/L

EC50


Chemical Name Carcinogen Status Exposure limitsHydrogen peroxide A3 Mexico: TWA 1 ppm Mexico: TWA 1.5

mg/m3

Mexico: STEL 2 ppm Mexico: STEL 3mg/m3


Chemical Name Hazardous Substances RQs


Extremely Hazardous SubstancesRQs

RQ


no

Chemical Name Massachusetts New Jersey Pennsylvania Illinois Rhode Island

Hydrogen peroxide

DMSO X

1000 lb

Hydrogen peroxide X X X X





Reactive Hazard


Full text of H-Statements referred to under sections 2 and 3H302 - Harmful if swallowed H332 - Harmful if inhaled H335 - May cause respiratory irritation H314 - Causes severe skin burnsand eye damage H318 - Causes serious eye damage H319 - Causes serious eye irritation H315 - Causes skin irritation

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Revision Date 02-Sep-2015

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End of MSDS







Product name 17 beta Estradiol Standard 0


Signal WordWarning



2. HAZARDS IDENTIFICATIONGHS - Classification

_____________________________________________________________________________________________

Recommended use

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Abcam Inc1 Kendall Square, Ste 341Cambridge, MA 02139-1517USATel: (617)225-2272 or 888-77-ABCAM (22226) (US toll free)Fax: (866) 739-9884 or (866) 457-9616 (both US toll free)

Supplier Address

_____________________________________________________________________________________________Revision Date 02-Sep-2015AB108667-CP91842 - 17 beta Estradiol Standard 0



Other information





55965-84-9 <0.1 Skin Corr. 1B (H314) Skin Sens. 1 (H317)






Weight %



3.1 Substances





_____________________________________________________________________________________________


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Proclin

_____________________________________________________________________________________________Revision Date 02-Sep-2015AB108667-CP91842 - 17 beta Estradiol Standard 0


Sensitivity to Static Discharge



none.

Explosion Data



Sensitivity to Mechanical Impact


none.













Environmental precautions

_____________________________________________________________________________________________

Try to prevent the material from entering drains or water courses.



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_____________________________________________________________________________________________AB108667-CP91842 - 17 beta Estradiol Standard 0 Revision Date 02-Sep-2015



Chemical Name LD50 Oral LD50 Dermal LC50 InhalationSodium EDTA 10 g/kg ( Rat )



Chronic toxicity









Acute toxicity


Odor Threshold











Odor




Autoignition temperature

_____________________________________________________________________________________________


Physical State @20°C No information available

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No information availableFlammability Limits in AirExplosion limits No information available


yes


ADR


Not dangerous goods

Fire Hazard no

DOT


Not dangerous goods

Reactive Hazard no

15. REGULATORY INFORMATIONU.S. Federal Regulations



IATA


Not dangerous goods


SARA 311/312 Hazard Categories Acute Health Hazard

Toxicity tomicroorganisms










_____________________________________________________________________________________________

Ecotoxicity

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Chemical Name Toxicity to algae Toxicity to fish







End of MSDS


Full text of H-Statements referred to under sections 2 and 3H314 - Causes severe skin burns and eye damage H317 - May cause an allergic skin reaction H400 - Very toxic to aquatic lifeH410 - Very toxic to aquatic life with long lasting effects H318 - Causes serious eye damage H302 - Harmful if swallowed


_____________________________________________________________________________________________



Revision Date

Page 64 / 64

02-Sep-2015

Documents

Kit Summary - Antibodies, Proteins, Kits and Reagents for … · 2015-09-02 · Proclin - 55965-84-9 0.0015 T; R20/21/22 C; R34 R43 N; R50-53 ... (300 pg/mL) Chemical Name EC-No CAS-No