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Functional Medicine Approach to Liver DetoxificationDr. Daniel Khalish

© Dan Khalish, D.C.http://www. kalishresearch.com 1

Kalish Method Functional M di i T i i PMedicine Training Program

Dr. Dan Kalish

kalishresearch.comkalishresearch.com800‐616‐7708

[email protected]

THREE LEVELS OF FUNCTIONAL MEDICINE

LEVEL 2 LEVEL 3LEVEL 1

Following the Arrows: Type 3 - Compound Following the Arrows: Type 3 - Compound

Body

Systems

SymptomsRoot

Causes

Mercury Detox

G.I. / YeastOvergrowth

Cognitive

Sugar Cravings

Mercury Exposure

Detox Overload

Adrenal Burnout(5‐10 Years)

Obesity, Fatigue & Depression

CognitiveImpairment



Body System 3: Detox

Can occur in following situations:

-artist using oil paints-welder, painter, photographer, printer

Body System 3: Detoxification

printer-mold exposure-daily tuna consumption (mercury)

Body System 2: GI

Decreased immuneresponse

Body System 1: HormonalBody System 2: GI Has to be optimized forabsorption of nutrients

needed to detox

Increased inflammation

Cortisol runs detox pathways

Healthy Living Inside and Out

• THE PROBLEM: We are facing an unprecedented assault on our health and the health of the environment with the generation of billions of tons of chemicals, heavy metals, pesticides, herbicides and petrochemical derivatives

• This is creating a real impact on our food and water supplies and ultimately impacts our health by damaging neuron bundles



Healthy Living Inside and Out

• THE PROBLEM ON THE INSIDE: heart disease, cancer, diabetes, obesity and DEPRESSION are related to poor lifestyle choices and a dramatic increase in toxins in our food and water

• THE PROBLEM ON THE OUTSIDE: destruction of the l i i di l f h inatural environment is a direct result of poor choices

in terms of industrial waste generation and disposal and burning of fossil fuels

SOLUTIONS

• We can help the health of the planet and at the same time improve our health and well being through simple detoxification programs

• Health issues that respond well to detoxHealth issues that respond well to detox programs: – Obesity

– Fatigue

– Depression



What is Detoxification?

• Detoxification is the process of• Detoxification is the process of transforming fat soluble toxins into a more polar form that may then be excreted from the body.

ToxinsA Toxin is a substance that causes harmful effects to our body.

When toxin levels are in excess of our body’s capacity to remove them toxins build up and are storedthem, toxins build up and are stored.

• Environmental Toxins

• Lifestyle Toxins

• Emotional Toxins

• Internal Toxins• Internal Toxins

– Metabolic reactions

– Intestinal microbes



Environmental Toxins consist of:

• Polluted air from factories

• Auto exhaust

• Solvents (paints, cleaning products)

• Heavy metals

• Pesticides, herbicides, insecticides

• Radiation

• Inhalants

Lifestyle Toxins:

• Nicotine

• Alcohol

• Caffeine

• Recreational & prescription drugs

• OTC drugs

– Dietary choices Fast foods, fried/refined foods, high sugar foodssugar foods

– Artificial food additives/colors/preservatives

– Meats that contain hormones and antibiotics



Internal Toxins

• Bacterial, yeast, fungal overgrowth

B d t f t b li ti ( b di id• By‐products of metabolic reactions (carbon dioxide, ammonia, hormones)

• Undigested food

• Stress (fries brain cells, remember the egg?)

• Unresolved trauma or abuse (experienced as a child or as an adult)

• Unhappy relationships

Signs That Your Detoxification Capacity Might Be Impaired

ANY SYMPTOM THAT HAS TO DO WITH YOUR BRAIN, memory – concentration –focus – ADD – ADHD – depression – fatigue –overeating



So What can you Do?

• Reduce your exposure to toxinsy p

• Remove some of the accumulated toxins in your body

• Improve the functioning of your main organs of elimination (digestive system, liver and skin)

HEALTHY LIVER

Toxins are correctly detoxified and consequently excreted



Unhealthy Liver

• Incomplete d t ifi ti fdetoxification of toxins

• Toxins leave the liver and are stored in tissues such as fat, the brain and thethe brain and the nervous system

Why should you Detoxify?

T F l B tt• To Feel Better

• To Improve Brain, Liver and Digestive Health

• To Maintain Optimum Sense of Well BeingBeing



Liver Detox Pathways

• Phase One: B Vitamins, Glutathione, Antioxidants, Vitamin C, Vitamin E

• Phase Two: Glycine, Taurine, Glutamine, Cysteine

Which Detox Pathways are Blocked?

• Through the Organix Profile you can determine which detox pathways require support



DETOXIFICATION PATHWAYS

Toxicants & Detoxification

• Detox Indicators (arginine NAC methionine• Detox Indicators (arginine, NAC, methionine, Mg, antioxidants)

– Abonormal levels indicate need for glutathione precursors (NAC, vitamin C)

– Also, taurine, cysteine, glycine etc.



What is Antioxidant Protection Level

• Organix Test shows how much this must then be balanced by appropriate anti‐oxidant protection

• Basic level required if low in anti oxidants• Basic level required, if low in anti‐oxidants extra support will be needed

Antioxidant Levels



Antioxidant Levels

• Oxidative Damage/Antioxidants• Oxidative Damage/Antioxidants

– Vitamin C, E + other antioxidants

– C+E are easily burned through under stress of detox programs, need to support

Two Types of Supplement Protocols

• You can use both supportive supplements that help liver function improve

• Coupled with detoxification products that will stimulate the body to dump toxins out of storageof storage

• Balance these two approaches:– Basic Rule, “Do No Harm”



Test for Presence of Heavy Metals

• 6‐8 Hour Challenge Test with DMSA

• Detects Lead, Mercury, Arsenic, Cadmium etc.



Heavy Metal Detox Programs

• Kinder, gentler versions, apple pectin fiber, chlorella, antioxidants, liver support products

• More aggressive approach DMSA use carefullycarefully

Main Issues

What Detoxification Pathways Are Blocked?

What Anti‐oxidant Protection Does the Patient Require

Tying the patients symptoms back to the detox issue: FOCUS ON NEURON BUNDLE DAMAGE



Impact on the Brain

• Based on my clinical experience a common underlying cause of weight gain, fatigue and depression includes neurotransmitter dysfunction as a direct result of neuro‐toxin exposure

• Neurotransmitter dysfunction can result from nutritional deficiencies and neurotoxicity

Neurotoxicity

• Neurotoxicity is a leading cause of depression, fatigue and weight gain. Neurotoxicity refers to damage to the neuron bundles in the brain from neurotoxic drugs; neurotoxic pesticides and herbicides; heavy metals such as mercury and lead.

• When you really think about how neurotoxic our food and water supply has become it is amazing we can be happy or think at all!supply has become, it is amazing we can be happy or think at all!



Neurotoxins

• Neurotoxins destroy the firing capacity of neuron bundles. This leaves us with neuron bundles that do not conduct the nerve impulses we require to feel happy and at peace.

• Therefore we experience the results of low serotonin and low dopamine, namely, anxiety, depression, sleep disorders, brain fog, poor memory and a general lack of enthusiasm for living life to its fullest; we become “depressed”.fullest; we become depressed .

• The pre-synaptic neuron, the synapse, and the post-synaptic neuron.

Electrical Transport in the Brain

p y p

}

Synapse

Neurotransmitters

Pre-synaptic Neuron

Post-synaptic Neuron



Kalish Method Functional M di i T i i PMedicine Training Program

Dr. Dan Kalish

kalishresearch.comkalishresearch.com800‐616‐7708

[email protected]

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