Dignostic Accuracy of the 2004 Indonesian Pediatric Society Medical Standard of Care for Neonatal SepsisOki Fitriani, Purnomo Suryanto,Setya wandita, Tunjung Wibowo, Eka L. Haksari, Madarina JuliaPediatricia Indonesiana, vol. 52, no. 2 March 2012

BACKGROUNDIPS proposeda medical standard of care to diagnose neonatal sepsis

OBJECTIVETo evaluate the diagnostic accuracy of the IPS medical standard of care 2004 to diagnose neonatal sepsis

METHODSTo evaluate the diagnostic accuracy of the IPS medical standard of care 2004 to diagnose neonatal sepsis Perinatal ward of Dr. Sardjito Hospital,Yogyakarta, Indonesia June - November 2010

Continued.Inclusion criteria

Continued.Exclusion criteria

Continued.To evaluate the diagnostic accuracy of the IPS medical standard of care 2004 to diagnose neonatal sepsis Phase 1Phase 2Phase 3193 neonatesAssessed by IPS medical standardof care for neonatal sepsisBlood culture

Continued.Categories ADifficulty breathingShortness of breathSeizureLack of consciousnessTemperature instabilityUnsterile delivery processDeteriorating condition

IPS CRITERIACategories BLethargyReduced activityIrritabilityVomitingBloatingSigns appearing after the 4th of lifeMeconium-stained amniotic fluidPoor feeding

RESULTTo evaluate the diagnostic accuracy of the IPS medical standard of care 2004 to diagnose neonatal sepsis

Continued.

Continued.

Continued.

DISCUSSIONTo evaluate the diagnostic accuracy of the IPS medical standard of care 2004 to diagnose neonatal sepsis Adding simple laboratory examination

Continued.Gram negativemicroorganism (62,5%)

Continued.Blood Culture(-)Errors samplingOrganism requiring a spesificmethods to isolateMethods of bloodsamplingInappropriate site drawingsPeripartum maternalantibiotic theraphyPrevious antibiotic treatmentof the neonates

CONCLUSIONTo evaluate the diagnostic accuracy of the IPS medical standard of care 2004 to diagnose neonatal sepsis The 2004 IPS medical standard of care showed adequate sensitivity for diagnosing neonatal sepsis, but its low specificity its use as a diagnostic tool

Pendahuluan 300 juta penduduk dunia yg membawa gen talasemia dan 300.000 nayi dengan talasemia dilahirkan setiap tahun Penderita talasemia di Indonesia 8 jt jiwa dan 3000 penderita baru setiap tahunnyaTALASEMIAMerupakan kelompok anemia hemolitik kongenital yang diturunkan secara autosomal resesif dimana terjadi defek pada sintesis rantai polipeptida yang menyusun molekul globin dalam hemoglobin

BACKGROUNDKerusakan dan kematian sel

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