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J O T JOURNALOF ORTHOPAEDIC TRAUMA www.jorthotrauma.com OFFICIAL JOURNAL OF Belgian Orthopaedic Trauma Association Canadian Orthopaedic Trauma Society Foundation for Orthopedic Trauma International Society for Fracture Repair The Japanese Society for Fracture Repair Orthopaedic Trauma Association AOTrauma North America Special Case Report Series CASE REPORTS

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JOT

JOURNALOF ORTHOPAEDIC

TRAUMA

www.jorthotrauma.com

OFFICIAL JOURNAL OF

Belgian Orthopaedic Trauma Association

Canadian Orthopaedic Trauma Society

Foundation for Orthopedic Trauma

International Society for Fracture Repair

The Japanese Society for Fracture Repair

Orthopaedic Trauma Association

AOTrauma North America

Special Case Report Series

CASE REPORTS

The Utility of Semi-Extended Tibial Nailing Utilizing theSuprapatellar Approach in the Treatment of an Open Proximal

Tibial Fracture With Vascular InjuryDaniel N. Segina, MD and Ryan M. Wilson, PA-C, MPAS

Summary: Fractures of the proximal tibia are technically difficultto surgically repair noting a high incidence of complications,especially malalignment. This demonstrative case is of a 52-year-old woman involved in an auto versus motorcycle collisionsustaining an isolated, open, proximal left tibia and fibulafracture. Extensive soft tissue stripping and exposed bone wasnoted at presentation. Plantar sensation was intact; however, thepatient demonstrated no motor dorsiflexion function and pulseswere undetectable. Imaging studies including angiography con-firmed the clinical diagnosis of an open tibia fracture withvascular injury. Surgical debridement and temporary stabilizationalong with revascularization was urgently performed. Subsequentfree tissue transfer and intramedullary stabilization using a supra-patellar entry portal for tibial nail insertion was performed in thesemiextended position. Eventual infection and nonunion wassuccessfully treated with hardware removal, revision nailing andautograft bone grafting. Bone healing without infection was ableto be achieved with good clinical outcome. The case demonstratesthe utility of the suprapatellar nailing technique in the semi-extended position, particularly with the avoidance of vasculargraft disturbance and prevention of malalignment.

Key Words: semiextended, suprapatellar, tibia nailing,malalignment

INTRODUCTIONProximal tibial fractures present a clinical and technical

challenge because of the difficulty of obtaining and maintainingreduction until fracture union.1–4 Surgical adjuvants are commonlyused to overcome these challenges.1–4 The suprapatellar nailingtechnique in the semiextended position can be a useful techniquein the treatment of these difficult injuries.

PRESENTING CONCERNSThis case report concerns a 52-year-old woman motorcycle

passenger injured after being struck by an automobile. She wastransported from the accident scene as a designated trauma alert toour trauma center. Full ATLS protocol was initiated.

CLINICAL FINDINGSThe patient was awake and alert with a GCS of 15. She was

hemodynamically stable with her only complaint of pain to her leftlower extremity. The patient relayed no significant current medicalproblems, medical history, surgical history, or previous injury toher left leg. Her family history was negative for musculoskeletaldisease, bleeding dyscrasias, or problems with anesthesia. Themusculoskeletal assessment of her bilateral upper extremities,pelvis, spine, and right lower extremity was negative. An isolatedinjury to her left leg below the knee was noted with exposedmuscleand bone. Detailed evaluation of the left lower extremity revealedintact plantar sensation. Plantar flexion of the ankle and toes wasnoted to be intact. Extensor function at the foot was absent alongwith no dorsal foot sensation. Vascular examination revealedabsent dorsalis pedis and posterior tibialis pulses.

Accepted for publication January 5, 2016.

From the Holmes Regional Trauma Center, Melbourne, FL.

D.N. Segina is a consultant for Stryker, Breg, and Eli Lilly and an owner/shareholder of Genesis Medical LLC, Motion Devices LLC, and BreakingAway Consulting LLC. The remaining author reports no conflict of interest.

Reprints: Daniel N. Segina MD, Holmes Regional Trauma Center, 1350Hickory St, Melbourne Florida 32901 (e-mail: [email protected]).

The views and opinions expressed in this case report are those of theauthors and do not necessarily reflect the views of the editors of Journalof Orthopaedic Trauma or Stryker.

Copyright © 2016 Wolters Kluwer Health, Inc. All rights reserved.

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Copyright � 2016 Wolters Kluwer Health, Inc. Unauthorized reproduction of this article is prohibited.

DIAGNOSTIC FOCUS AND ASSESSMENTBroad spectrum IV antibiotics for gram positive and gram

negative organisms and tetanus toxoid were urgently administered.Radiologic evaluation confirmed the diagnosis of tibial and fibularfracture with a proximal, segmental fracture pattern. (Fig. 1) Addi-tionally, acute angiography was performed demonstrating com-plete vascular compromise at the inferior margin of the poplitealartery. (Fig. 2) The final diagnosis was a type III C open proximalleft tibia fracture.

THERAPEUTIC FOCUS AND ASSESSMENTEmergent orthopaedic and vascular surgery intervention was

undertaken. Surgical debridement with temporary skeletal stabili-zation using a small fragment plate and external fixation wasrapidly accomplished. (Fig. 3) Revascularization using a reversesaphenous interposition graft successfully restored perfusion to thelower limb and foot. Serial debridements, every 48 hours, wereundertaken over the ensuing week with no active infection appre-ciated. Definitive stabilization of the fracture was accomplished 6days after injury with the placement of a reamed, locked, tibialintramedullary nail using the suprapatellar nailing technique inthe semiextended position. The temporary small fragment platewas retained to assure proximal fracture reduction. (Figs. 4A–F)Free tissue transfer was accomplished at the same time using theipsilateral gracilis muscle and split thickness skin graft.

FOLLOW-UP AND OUTCOMESThe patient was discharged to home at 14 days after injury.

Initial follow-up occurred at 2 weeks after discharge noting no

clinical signs of infection and nearly 100% take of her grafts.Sutures were removed and full range of motion was allowed.Follow-up occurred 8 weeks after discharge where the initialpostoperative x-rays were obtained. Maintenance of reduction andearly callous formation were noted. Progressive weight bearing astolerated was allowed. Formalized physical therapy was alsoordered. Bimonthly follow-up continued until 8 months aftersurgery. Radiographs at that time revealed interval callousformation and well-maintained alignment. (Figs. 5A, B) Kneerange of motion was from 5 to 110 degrees. Passive ankle rangeof motion was from 0 to 25 degrees. No active range of motion ofthe ankle was noted. The patient continued follow-up with her localorthopaedic surgeon for the next 13 months (she lived 4 hoursaway). She did return 21 months after injury with complaints ofincreasing pain and active drainage from her proximal tibia. Diag-nostic workup at that time included serologic studies; computedtomography and Indium-labeled white blood cell scan (Figs. 6, 7).Infected proximal tibial nonunion was diagnosed. Her distal diaph-yseal fracture was noted to be healed. Staged surgical treatment wasinitiated beginning with hardware removal, deep cultures, antibi-otic impregnated PMMA intramedullary nail, and IV antibiotics.

FIGURE 1. Initial AP radiograph demonstrating a segmental,comminuted tibia/fibula fracture.

FIGURE 2. Acute angiography demonstrating complete arterialdisruption.

Segina and Wilson

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The nail was removed through an infrapatellar entry portal (Figs.8A, B). An infectious disease consultation was obtained with IVantibiotic therapy continued for 6 weeks. Serologic studies ob-tained after the conclusion of antibiotic therapy were noted to benormal. Surgical treatment at the time was performed includingstabilization with a larger diameter tibial nail and autograft bonegraft. Sevenmonths later,final follow-up occurredwith clinical andradiographic signs of fracture union (Figs. 9A, B). Additionally,serologic studies were normal. Final knee range of motion was5–105 degrees. Final radiographs revealed anatomic coronal plane

alignment with 5 degrees of procurvatum. She wears an AFO forlack of ankle and toe dorsiflexion function. She does have chronicpain issues managed with nonnarcotic pain medicine. She has re-turned to work. Her spouse is an above the knee amputee from thesame accident (Figs. 10A, B).

DISCUSSIONFractures of the proximal tibia present a challenging problem

particularly from a surgical reconstruction perspective. Options forsurgical repair are divided between plating or nail fixation.

FIGURE 3. A–C, Intraoperative clinical photograph and fluoroscopic images demonstrating acute debridement and temporary sta-bilization.

FIGURE 4. A–F, Intraoperative fluoroscopic images demonstrating the suprapatellar technique and final hardware implantation.

Proximal Tibial Fracture With Vascular Injury

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Copyright � 2016 Wolters Kluwer Health, Inc. Unauthorized reproduction of this article is prohibited.

Bhandari conducted a meta-analysis of data published concerningproximal tibia fracture treatment. Although they graded theevidence as weak, they were able to demonstrate trends in surgicaltreatment options. Plate fixation was associated with a higherincidence of infection, whereas nails were associated with a higherincidence of malunion.5

FIGURE 5. A and B, 8 months postoperative AP andlateral radiographs demonstrating posterior bridgingcallous.

FIGURE 6. Coronal computed tomograhic image revealing per-sistent fracture line supporting the diagnosis of nonunion.

FIGURE 7. Indium-labeled white blood cell scan demonstratingsignificant uptake in the proximal tibia supporting the clinicaldiagnosis of infection.

Segina and Wilson

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Recent studies have demonstrated similar incidence of malre-duction and malunion (8%–36%).1–4 Additionally, these studiescommented on the need for reduction aids when nail fixation ischosen for fracture repair to avoid malreduction.1,2 One of theseaids revolves around the use of the suprapatellar nailing techniquewith the tibia in the semiextended position. This technique allowsfor the limb to be placed in a semiextended position that reduces the

extension moment through the proximal tibia and thus reducing thepotential for a procurvatum deformity. The technique also facili-tates a more accurate entry portal, which assists in obtaining a moreanatomic fracture alignment. Finally, this technique eliminates theneed for limb repositioning that is needed using a traditional in-frapatellar entry portal. Prospective studies recently published havedemonstrated benefit of the suprapatellar nailing technique with

FIGURE 8. A and B, Intraoperative lateral fluo-roscopic images demonstrating infrapatellar nailremoval and temporary antibiotic nail placement.

FIGURE 9. A and B, AP and lateral radiographs,7 months after revision nail fixation and bonegrafting, demonstrating healed nonunion.

FIGURE 10. A and B, Final clinical photographsincluding the patient’s spouse with his AKAprosthesis.

Proximal Tibial Fracture With Vascular Injury

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excellent clinical and radiographic outcomes (Figs. 11A, B).6 Arecent prospective randomized trial has demonstrated similar out-comes, with respect to pain and knee range of motion, comparingsuprapatellar versus infraptellar tibial nail insertion portals.7

Nail design has evolved to provide improved interlockingoptions with superior biomechanical stability as compared withtraditional tibial nailing or plating.8,9 Multiple manufacturers havemodified their tibial nail insertion apparatus to take advantage ofthe semiextended nailing technique using the suprapatellar nailingportal. Elongated insertion handles, trochlear groove protectionsleeves, and extended reamers are now available.

Finally, this case study generates additional treatment chal-lenges because of the open fracture with associated vascular injuryrequiring repair (Gustillo Anderson Type III C). Choosing limbsalvage for this injury carries a significantly high complication rate,as experienced by this patient, and generates debate over preferredtreatment options. Amputation, acute or delayed, must be consid-ered a viable treatment option and is supported by prospective, peerreviewed data. That having been said, data gathered from the LowerExtremity Assessment Project study does not demonstrate a clearadvantage to either treatment option when one considers long-termfunctional outcomes data. Decision making is multifactorial andshould be individualized to each patient.10

One of the confounding variables in formulating the treatmentplan was the fact that this patient’s husband was also injured in themotorcycle collision. He sustained a traumatic above the kneeamputation. Our patient categorically refused to consent to anamputation.

As with all case discussions, the information must be viewedwith the understanding that a single case is only one piece of datum.It does not hold up to the scrutiny needed to make broad changes toone’s practice. It does provide the reader/surgeon an entry pointinto evaluating techniques, which may improve clinical outcome incertain patients. For this case specifically, obtaining anatomicalignment while avoiding potential disruption of an acute vascularrepair are primary orthopaedic objectives. The utility of the

semiextended tibial nailing using the suprapatellar approach isa valuable tool in achieving these objectives.

REFERENCES1. Krieg JC. Proximal tibial fractures: current treatment, results, and prob-lems. Injury. 2003;34(suppl 1):A2–A10.

2. Lindvall E, Sanders R, Dipasquale T, et al. Intramedullary nailing versuspercutaneous locked plating of extra articular proximal tibial fractures.Comparison of 56 cases. J Orthop Trauma. 2009;23:485–492.

3. Nork SE, Barei DP, Schildhauer TA, et al. Intramedullary nailing ofproximal quarter tibial fractures. J Orthop Trauma. 2006;20:523–528.

4. Hiesterman TG, Shafiq BX, Cole PA. Intramedullary nailing of extra-articular proximal tíbia fractures. J Am Acad Orthop Surg. 2011;19:690–700.

5. Bhandari M, Audige L, Ellis T, et al; Evidence-based orthopaedic traumaworking Group. Operative treatment of extra-articular proximal tibial frac-tures. J Orthop Trauma. 2003;17:591–595.

6. Sanders RW, Dipasquale TG, Jordan CJ. Semiextended intramedullarynailing of the tibia using a suprapatellar approach: radiographic resultsand clinical outcomes at a minimum of 12 months follow-up. J OrthopTrauma. 2014;28:245–255.

7. Chan DS, Serrano R, Griffing R, et al. Supra- versus Infra-patellar tibialnail insertion: a prospective, randomized Control Pilot study. J OrthopTrauma. 2015. [Epub ahead of print].

8. Lee SM, Oh CW, Oh JK. Biomechanical analysis of operative methods inthe treatment of extra-articular fracture of the proximal tibia. Clin OrthopSurg. 2014;6:312–317.

9. Freeman AL, Craig MR, Schmidt AH. Biomechanical comparison of tibialnail stability in a proximal third fracture: do screw quantity and locked,interlocking screws make a difference? J Orthop Trauma. 2011;25:333–339.

10. MacKenzie EJ, Bosse MJ. Factors Influencing outcome following limb-threatening lower limb trauma: lessons learnd from the Lower ExtremityAssesment Project (LEAP). J Am Acad Orthop Surg. 2006;14:S205–S210.

T2-CS-6,10-2015

Read the rest of the JOT Case Reports online on www.jorthotrauma.com. It’s the Grand Rounds series from the Jour-nal of Orthopaedic Trauma, the official journal of the Ortho-paedic Trauma Association.

FIGURE 11. A and B, Intraoperative imagesdemonstrating the suprapatellar entry portaltechnique. Note the semiextended position of thelimb enhancing the capacity to fluoroscopicallyimage without limb manipulation or movement.

Segina and Wilson

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Copyright � 2016 Wolters Kluwer Health, Inc. Unauthorized reproduction of this article is prohibited.