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Introduction And Lipids · 2019. 4. 30. · Introduction And Lipids Author: aa Created Date: 4/30/2019 11:33:51 PM

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Page 1: Introduction And Lipids · 2019. 4. 30. · Introduction And Lipids Author: aa Created Date: 4/30/2019 11:33:51 PM

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Page 2: Introduction And Lipids · 2019. 4. 30. · Introduction And Lipids Author: aa Created Date: 4/30/2019 11:33:51 PM

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Page 3: Introduction And Lipids · 2019. 4. 30. · Introduction And Lipids Author: aa Created Date: 4/30/2019 11:33:51 PM

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Page 4: Introduction And Lipids · 2019. 4. 30. · Introduction And Lipids Author: aa Created Date: 4/30/2019 11:33:51 PM

The type of fatty acid that connects to L-glycerol phosphate 3

Phosphate are specific for different organisms, different tissues of the

same organisms, and different glycerophospholipids in the same cells

and tissues.

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Page 5: Introduction And Lipids · 2019. 4. 30. · Introduction And Lipids Author: aa Created Date: 4/30/2019 11:33:51 PM

Glycerophospholipid is named for the head group with the

prefix “Phosphotidyl”

Phosphatidylcholine– Lecithin

Phosphatidylethanolamine

Phosphatidylserine Cephalin

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Page 6: Introduction And Lipids · 2019. 4. 30. · Introduction And Lipids Author: aa Created Date: 4/30/2019 11:33:51 PM

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Page 7: Introduction And Lipids · 2019. 4. 30. · Introduction And Lipids Author: aa Created Date: 4/30/2019 11:33:51 PM

Sulfolipids have a sulfonated glucose residue joined to a

diacylglycerol in glycosidic linkage. They also exist

predominantly in chloroplast.

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Page 8: Introduction And Lipids · 2019. 4. 30. · Introduction And Lipids Author: aa Created Date: 4/30/2019 11:33:51 PM

Archaebacteria which live with some

extreme conditions such as high

temerature low pH, high ionic strength,

contain membranes that have long

chain(32 carbon) branched hydrocarbons

linked at each end to glycerol

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Page 9: Introduction And Lipids · 2019. 4. 30. · Introduction And Lipids Author: aa Created Date: 4/30/2019 11:33:51 PM

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Page 10: Introduction And Lipids · 2019. 4. 30. · Introduction And Lipids Author: aa Created Date: 4/30/2019 11:33:51 PM

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Page 11: Introduction And Lipids · 2019. 4. 30. · Introduction And Lipids Author: aa Created Date: 4/30/2019 11:33:51 PM

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Page 12: Introduction And Lipids · 2019. 4. 30. · Introduction And Lipids Author: aa Created Date: 4/30/2019 11:33:51 PM

Sphingomyelins are present in the plasma

membrane of animal cells, especially in myelin,

a membrane sheath that insulate the axons of

some neurons

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Page 13: Introduction And Lipids · 2019. 4. 30. · Introduction And Lipids Author: aa Created Date: 4/30/2019 11:33:51 PM

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Page 14: Introduction And Lipids · 2019. 4. 30. · Introduction And Lipids Author: aa Created Date: 4/30/2019 11:33:51 PM

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Page 15: Introduction And Lipids · 2019. 4. 30. · Introduction And Lipids Author: aa Created Date: 4/30/2019 11:33:51 PM

Phospholipids are degraded in Lysosome by

specific enzymes, Phospholipases 15

Page 16: Introduction And Lipids · 2019. 4. 30. · Introduction And Lipids Author: aa Created Date: 4/30/2019 11:33:51 PM

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Page 17: Introduction And Lipids · 2019. 4. 30. · Introduction And Lipids Author: aa Created Date: 4/30/2019 11:33:51 PM

Cholesterol is a derived lipid. Its widely

distributed as sterols in animals and humans

Its an essential component of cell membrane

Vit. D, hormones and bile acids are synthesised

from cholesterol.

Bile acids are essential for normal digestion

and absorption of fats and fat-soluble vitamins.

Most of the cholesterol is synthesised by the

liver

An increase in dietary intake of cholesterol,

increases its synthesis in the body as well

which leads to coronary heart diseases.

Unsaturated fats reduce the level of

cholesterol in blood. 17

Page 18: Introduction And Lipids · 2019. 4. 30. · Introduction And Lipids Author: aa Created Date: 4/30/2019 11:33:51 PM

Low density lipoproteins (LDL) transports

cholesterol from liver through blood to the

tissues (Bad cholesterol)

High density lipoprotein (HDL) transports

cholesterol from blood to the liver where it

is metabolised (Good cholesterol)

LDL Cholesterol High risk of heart

attack

HDL Cholesterol Low risk of heart

attack

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Page 19: Introduction And Lipids · 2019. 4. 30. · Introduction And Lipids Author: aa Created Date: 4/30/2019 11:33:51 PM

Bile Acids are polar derivatives of cholesterol that

act as detergents in the intestine, emulsifying

dietary fats to make them more accessible to

digestive lipases

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Page 20: Introduction And Lipids · 2019. 4. 30. · Introduction And Lipids Author: aa Created Date: 4/30/2019 11:33:51 PM

Linoleic, Linolenic, and Arachidonic acids

Essential fatty acids synthesize structural fats

in tissues such as prostoglandins, leukotriens,

prostocyclins, thromboxane which regulate

body functions such as blood clotting,

inflammation etc.

Essential fatty acid deficiency can result in

abnormalities like poor growth, increase food

intake, scale inflammation of skin and

impaired immune response.

Best dietary sources are vegetable oils(corn

oil, sunflower oil) and oil rich fish (Herring ,

Sardine)

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