INFECTION AND IMMUNITYiai.asm.org/content/43/1/local/admin.pdf · Charles Carpenter (1985) Bruce Chassy ... Peter C., 202 Doring, Gerd, 161 Eisemann, Christine S., 143 Elo, ... Young,

INFECTION AND IMMUNITYVOLUME 43 * JANUARY 1984 NUMBER 1

J. W. Shands, Jr., Editor in Chief (1984)University of Florida, Gainesville

Phillip J. Baker, Editor (1985)National Institute ofAllergy and

Infectious DiseasesBethesda, Md.

Edwin H. Beachey, Editor (1988)VA Medical CenterMemphis, Tenn.

Peter F. Bonventre, Editor (1984)University of Cincinnati

Cincinnati, OhioArthur G. Johnson, Editor (1986)University ofMinnesota, Duluth

Stephan E. Mergenhagen, Editor (1984)National Institute of Dental Research

Bethesda, Md.

John H. Schwab, Editor (1985)University of North Carolina,

Medical SchoolChapel Hill

Leonard C. Altman (1986)Michael A. Apicella (1985)Roland Arnold (1984)Joel B. Baseman (1985)Elmer L. Becker (1984)Neil Blacklow (1984)Arnold S. Bleiweis (1984)William H. Bowen (1985)Robert R. Brubaker (1986)Ward Bullock, Jr. (1985)Charles Carpenter (1985)Bruce Chassy (1984)John 0. Cisar (1985)John Clements (1985)Myron Cohen (1984)Barry C. Cole (1984)R. John Collier (1984)Lynette Corbeil (1984)Jim E. Cutler (1984)Peter C. Doherty (1984)Judith E. Domer (1986)James L. Duncan (1985)Dennis Dwyer (1984)Roman Dziarski (1984)Robert A. Eisenberg (1984)Barry Eisenstein (1985)Toby Eisenstein (1984)Peter Elsbach (1986)Stanley Falkow (1985)John J. Farrar (1985)

EDITORIAL BOARDJohn C. Feeley (1985)Robert Finberg (1984)John R. Finerty (1984)Robert Fitzgerald (1986)Samuel B. Formal (1986)John Gallin (1985)Peter Gemski (1985)Robert Genco (1985)Ronald J. Gibbons (1985)Frances Gillin (1984)Mayer B. Goren (1985)Harry Greenberg (1985)Frank Griffin (1984)Richard Guerrant (1986)Carlton L. Gyles (1985)Edgar Hanna (1984)Eric J. Hansen (1986)David Hentges (1985)Martin S. Hirsch (1985)Randall K. Holmes (1986)Dexter H. Howard (1985)Barbara Iglewski (1986)Howard M. Johnson (1985)Russell C. Johnson (1985)William Johnson (1985)Garth W. Jones (1984)Dennis L. Kasper (1985)George E. Kenny (1984)David F. Keren (1985)Paul Kolenbrander (1986)

Julius P. Kreier (1986)Maurice J. Lefford (1984)Thomas Lehner (1986)Stephan H. Leppla (1985)Michael Loos (1984)John Mansfield (1985)Zell A. McGee (1985)Jerry R. McGhee (1985)Douglas D. McGregor (1985)Floyd C. McIntire (1985)Monte Meltzer (1986)Jiri Mestecky (1986)J. Gabriel Michael (1986)Page Morahan (1985)Frederick A. Murphy (1985)Henry W. Murray (1986)Neal Nathanson (1984)Robert J. North (1985)Alison O'Brien (1985)Itzhak Ofek (1986)Roy C. Page (1985)Chik H. Pai (1985)Monique Parant (1984)Nathaniel F. Pierce (1986)Matthew Pollock (1986)Ruth Rappaport (1986)John B. Robbins (1986)Donald Robertson (1984)Burton Rosan (1986)Jon A. Rudbach (1984)

Stephen W. Russell (1985)Catherine Saelinger (1984)Edward J. St. Martin (1985)Irvin E. Salit (1986)Anthony J. Sbarra (1984)Charles F. Schachtele (1985)Julius Schachter (1986)Jerome L. Schulman (1985)Alan Sher (1984)Gerald D. Shockman (1986)Phillip Smith (1985)Ralph Snyderman (1985)Maggie So (1986)J. G. Stevens (1985)Barnet M. Sultzer (1985)Catharina Svanborg-Eden (1985)John L. Swanson (1984)Diane Taylor (1984)Ivo van de Rijn (1984)Johannes van Houte (1985)Jan T. Vilcek (1985)Stefanie Vogel (1985)Peter A. Ward (1985)William P. Weidanz (1984)William 0. Weigle (1984)Jerry A. Winkelstein (1984)Herbert H. Winkler (1986)Meyer J. Wolin (1984)David J. Wyler (1984)Wendell D. Zollinger (1985)

Helen R. Whiteley, Chairman, Publications BoardLinda M. llig, Managing Editor, Journals

Walter G. Peter III, Director of PublicationsKaren Simon, Production Editor

Infection and Immunity (ISSN 0019-9567), a publication of the American Society for Microbiology, 1913 I St., NW,Washington, DC 20006, is devoted to the advancement and dissemination offundamental knowledge concerning: (i) infectionscaused by pathogenic bacteria, fungi, and unicellular parasites; (ii) the ecology and epidemiology of pathogenic microbes; (iii)virulence factors, such as toxins and microbial surface structures; (iv) nonspecific factors in host resistance and susceptibilityto infection; and (v) immunology of microbial infection. Instructions to authors are published in the January issue each year;reprints are available from the editors and the Publications Department. Infection and Immunity is published monthly, and thetwelve numbers are divided into four volumes per year. The nonmember subscription price is $249 per year; single copies are$21. The member subscription price is $37 (foreign, $49 [surface rate]) per year; single copies are $7. Correspondence relatingto subscriptions, reprints, defective copies, availability of back issues, lost or late proofs, disposition of submittedmanuscripts, and general editorial matters should be directed to the ASM Publications Department, 1913 I St., NW,Washington, DC 20006 (phone: 202 833-9680).

Claims for missing issues from residents of the United States, Canada, and Mexico must be submitted within 3 months afterpublication of the issues; residents of all other countries must submit claims within 6 months of publication of the issues.Claims for issues missing because offailure to report an address change or for issues "missing from files" will not be allowed.Second class postage paid at Washington, DC 20006, and at additional mailing offices.POSTMASTER: Send address changes to Infection and Immunity, ASM, 1913 I St., NW, Washington, DC 20006.Made in the United States of America.Copyright C) 1984, American Society for Microbiology. $: iltM. t, a ;+trt; (IIIJ.cAll Rights Reserved.The code at the top of the first page of an article in this journal indicates the copyright owner's consent that copies of the ar-

ticle may be made for personal use or for personal use of specific clients. This consent is given on the condition, however, thatthe copier pay the stated per-copy fee through the Copyright Clearance Center, Inc., 21 Congress St., Salem, MA 01970, forcopying beyond that permitted by Sections 107 and 108 of the U.S. Copyright Law. This consent does not extend to otherkinds of copying, such as copying for general distribution, for advertising or promotional purposes, for creating new collectiveworks, or for resale.

Author IndexAchtman, M., 368Alger, Nelda E., 442Ashton, Fraser E., 407Aspinall, Gerald O., 245Avila, Jose L., 402Azuma, Ichiro, 233

Babiker, Salah, 289Baca, Oswald G., 253Bard, Jonathan, 84Barg, Linda L., 183Baron, Samuel, 122Beachey, Edwin H., 122Beeder, Ann B., 108Berg, Rodney D., 6Berger, Elaine M., 435Bick, P. H., 326Bishop, Karen, 206, 213Black, Samuel J., 445Blackmon, Barbara, 195, 397Bolin, Ingrid, 72, 108Bouvet, A., 28Brehmer, Werner, 233Brennan, Patrick J., 245Bridger, Janice C., 133Brown, Carolyn, 386Brown, Joanna F., 133Brown, Mary B., 115Buchanan, Thomas M., 183Bynum, Lester M., 206, 213

Cabrian, Kathy, 314Carpenter, A. B., 326Case, Stephen E., 276Cassell, Gail H., 115Chase, Theodore, Jr., 320Cho, Sang-Nae, 245Cole, Barry C., 302Collins, Frank M., 32Connelly, Roberta J., 263Cooper, James, 206Costerton, J. William, 359Crist, Arthur E., Jr., 38Cryz, S. J., Jr., 440Curtiss, Roy, III, 195, 397

Dainelli, Benedetto, 189Dall, Lawrence, 359D'Antonio, Lawrence E., 442David, Hugo L., 438David, Victor, 353Davis, Charles E., 445Deck, Fred H., 206, 213Deitch, Edwin A., 6Delisle, Gloria J., 11Della-Porta, A. J., 413Devi, Shamala, 429Doherty, Peter C., 202Doring, Gerd, 161

Eisemann, Christine S., 143Elo, Jaakko, 149Enright, Fred M., 43

Falkow, Stanley, 101, 108,156, 263, 353

Ferrante, Antonio, 238Flaherty, Dennis K., 206, 213Friedlander, Arthur M., 283Friedman, Herman, 314, 347Fujiwara, Tsuyoshi, 245Furer, E., 440

Galloway, Darrell R., 49Germanier, R., 440Goldman, Ron, 386Gonzales, Frank R., 14Graham, Leroy, Jr., 79Grihn, Erik M., 308Greenblatt, Hellen C., 337Greenspan, Neil S., 202Griffith, Ronald W., 66

Halevy, Menachem, 14Hall, Graham A., 133Hedstrom, Richard C., 49Hetrick, Frank M., 59Hirayama, Toshiya, 21H0iby, Niels, 161Holt, S. C., 166, 178Hood, Mary A., 213Houston, Clifford W., 93Howard, D. H., 380Huff, Timothy, 122Hunter, Shirley W., 245Hurwitz, Julia L., 202

Jack, Richard M., 445Jahrling, Peter B., 283Jarrett, R. G., 413Jeffers, Gale W., 43Jennings, Harold J., 407Jerrells, Thomas R., 59Johansen, Kirsten Staehr, 435Johnson, William, 347Johnston, Mona R., 421

Kaeberle, Merlin L., 66Kan, Siu-Chow, 276Kato, Iwao, 21Keshavarz-Valian, Hossein,442

Khanolkar, Saroj R., 183Kharazmi, Arsalan, 161Kirkpatrick, Tim L., 253Klei, Thomas R., 43Klein, Thomas, 314, 347Klucinski, Wlodzimierz, 289Koo, Felix C. W., 93Koomey, J. Michael, 101Korhonen, T., 368Korhonen, Timo K., 149Koster, F. T., 253Kothary, Mahendra H., 320Kramer, Kenton J., 276Kusecek, B., 368

Laitinen, Lauri A., 308Lange, Werner, 233Lark, David, 353Lehtonen, Olli-Pekka J., 308Leong, Yap Kok, 429

Levitt, Daniel, 84Liebert, Cynthia, 213Lipton, Howard L., 432Low, David, 353Lugowski, Czeslaw, 407

Macmillan, James D., 320Maejima, Kazuyoshi, 6Makela, P. Helena, 149Malamud, Daniel, 386Marzouk, Joe, 359Masihi, K. Noel, 233Maurelli, Anthony T., 195,

397McKenzie, Ian F. C., 429McLaughlin, John, 294McPhee, Dale A., 413Mercer, A., 368Merrill, Paul, 283Milazzo, Francis H., 11Mills, John, 359Minion, F. Chris, 115Mishell, R., 178Molina, N. Christine, 93Moon, H. W., 1Moskophidis, Matthaus, 127Muller, Ferdinand, 127Muller, Sybille, 233Murphy, James R., 38

Navalkar, Ram G., 79Nonnecke, Brian J., 289Nypaver, Matthew J., 143

Odagiri, Yoshiharu, 54Ofek, Itzhak, 257Ohishi, Iwao, 54Orme, Ian M., 320rskov, Frits, 1490rskov, Ida, 149Osterman, Joseph V., 143

Palmer, Bennie A., 59Pang, Tikky, 429Paretsky, D., 14Park, Hydow, 139Parsonson, I. M., 413Pavlovskis, Olgerts R., 49Peacock, Marius G., 421Peppler, Mark S., 217, 224Perry, Alex, 257Peterson, Johnny W., 93, 122Pierce, Nathaniel F., 341Pluschke, G., 368Portis, John L., 421Portnoy, Daniel A., 108Progulske, A., 166, 178Pruzzo, Carla, 189Pulliam, Lynn, 359

Ranney, R. R., 326Reed, Sharon L., 445Repine, John E., 435Ricchetti, Miria, 189Rieber, Manuel, 402

Rojas, Miguel, 402Rosenstreich, David L., 337Roth, James A., 66Rowatt, James D., 253Rozhon, Edward J., 432Runnels, P. L., 1Ryu, Hyoik, 66Rzepczyk, Christine M., 238

Saul, Allan J., 238Schoolnik, Gary, 353Schrumpf, Merry E., 217Schumacher, H. Ralph, 139Schwartz, David H., 202Searls, Lisa, 314Siddiqui, Wasim A., 276Siitonen, Anja, 149Singleton, Fred, 213Smith, Larry R., 206, 213StAhlberg, Tom H., 308Stanton, G. John, 122Steiner, Craig M., 432Stephens, Richard S., 263Stewart, Scott, 421Stibbs, Henry H., 263Sully, E. C., 326Svenson, Stefan B., 149

Targowski, Stanislaw P., 289Thomas, Leo A., 421Thorel, Marie-Frangoise, 438Thorpe, Ruth N., 302Timmis, K. N., 391To, Sam C.-M., 1Tobery, Steven, 283Torian, Bruce E., 263Trummel, C., 178

Vaisanen, Eino, 149Vaisanen, V., 368Vaisanen-Rhen, Vuokko, 149Valerius, Niels H., 161van de Rijn, I., 28

Watanabe, H., 391Weigent, Douglas A., 122Weiss, Alison A., 263Welch, Rodney A., 156Widen, Raymond, 314, 347Williams, Jim C., 421Wilson, Walter, 359Winzenburger, Peggy, 206,213Wisseman, Charles L., Jr., 38Witmer, W. Byron, 206, 213Wloch, H., 368Wolf-Watz, Hans, 72, 108Wu-Hsieh, B., 380

Yamaga, Karen M., 276Yeen, Wong Phooi, 429Young, Douglas B., 183

Zeiger, Allen R., 139Zlotnik, A., 380

INFECTION AND IMMUNITY, Jan. 1984

INFECTION AND IMMUNITY

INSTRUCTIONS TO AUTHORS

HOW TO SUBMIT MANUSCRIPTSSubmit manuscripts directly to the ASM Publica-

tions Department, 1913 1 Street, NW, Washington, DC20006. The manuscript should be accompanied by acovering letter stating the following: the journal towhich the manuscript is being submitted; the mostappropriate section of the journal; the address andtelephone number of the corresponding author; andthe former manuscript number (if it is being resubmit-ted). In addition, include written proof that permissionto cite personal communications and receipt of pre-prints has been granted.

Submit two complete copies of each manuscript,including figures and tables. The manuscript may beeither the original typescript or clear, clean copies.Type every portion of the manuscript double space,including figure legends, table footnotes, and Litera-ture Cited, and number all pages in sequence, includ-ing the abstract, tables, and figure legends. Place thelatter two items after the Literature Cited section. Theuse of paper with numbered lines is recommended.Submit figures as glossy or mat-finish photographs.(See p. iv for detailed instructions.) Copies of "inpress" manuscripts that are important for judgementof the submitted manuscript should be enclosed tofacilitate the review.Authors who are unsure of proper English usage

should have their manuscripts checked by someoneproficient in the English language. Manuscripts maybe rejected on the basis of poor English or lack ofconformity to accepted standards of style.

EDITORIAL POLICYManuscripts submitted to Infection and Immunity

(IAI) must represent reports of original research thathave not been previously published and that are notbeing considered for publication elsewhere. All au-thors of a manuscript are responsible for the content oftheir manuscript, including appropriate citations andacknowledgments.

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It is anticipated that page charges, currently $30 perprinted page (price subject to change), will be paid byall authors who have funds available from their institu-tion or from the sponsor of the research. A bill for pagecharges will be sent with the page proofs and reprintorder form.

If funds for payment of page charges are not avail-able, a request to waive the charges must be sent toWalter G. Peter III, Director of Publications, Ameri-can Society for Microbiology, 1913 I St., NW, Wash-ington, DC 20006, immediately after receipt of theletter stating that the manuscript has been received bythe Publications Department. Such a request, which

should be accompanied by a copy of the Acknowledg-ments section of the paper, will in no way affect reviewof the manuscript.

CopyrightTo maintain and protect the Society's ownership

and rights and to be able to protect the original authorsfrom misappropriation of their published work, ASMrequires authors to sign a copyright transfer agree-ment. This agreement is sent to the submitting authorwhen the manuscript is accepted for publication. Un-less this agreement is executed, ASM will not publish themanuscript. (U.S. government employees may file astatement attesting that a manuscript was prepared aspart of their official duties. If they elect to do so, theyshould not sign the ASM copyright transfer agree-ment.)

ScopeIAI is devoted to the advancement and dissemina-

tion of fundamental knowledge concerning (i) infec-tions caused by pathogenic bacteria, fungi, and unicel-lular parasites; (ii) ecology and epidemiology of patho-genic microbes; (iii) virulence factors, such as toxinsand microbial surface structures; (iv) nonspecific fac-tors in host resistance and susceptibility to infection;and (v) immunology of microbial infection.

IAI will consider papers concerned with the ecologyof pathogenic microbes. Clinical descriptions and pa-pers concerning the microbiology of hospital environ-ments should be submitted to the Journal of ClinicalMicrobiology. Papers concerned with environmentalecology should be submitted to Applied and Environ-mental Microbiology.

IAI will consider papers concerned with specific andnonspecific immunity to microorganisms, includingthe function of phagocytes, lymphocytes, immuno-globulins, and other factors. Studies of basic immunol-ogy and tumor immunology are more appropriate fornon-ASM journals.IAI will consider papers describing experimental

models of infections and the pathological conse-quences of infection. In addition, the journal willconsider papers describing microbial products that areor may be related to pathogenesis. Microbial productsor activities that are described and related to diagnosisshould be submitted to the Journal ofClinical Microbi-ology. If papers contain extensive taxonomic material,they should be submitted to the International Journalof Systematic Bacteriology.

IAI will not consider papers concerned with antimi-crobial therapy. These should be submitted to Antimi-crobial Agents and Chemotherapy.

IAI will not consider papers concerned with viralinfections. These should be submitted to the Journalof Virology.


IAI will consider papers concerned with unicellularparasites. Those dealing with multicellular parasitesare usually not accepted unless the paper is concernedwith immune modulation by parasites or their prod-ucts.

Papers describing methodology are not encouraged;only under unusual circumstances will they be consid-ered for publication.

Questions about these guidelines may be directed tothe editor in chief of the journal being considered.Note that a manuscript rejected by one ASM journal

on scientific grounds or on the basis of its generalsuitability for publication is considered rejected by allother ASM journals.

Editorial StyleThe editorial style of ASM journals conforms to the

Council of Biology Editors Style Manual (5th ed.,1983; Council of Biology Editors, Inc., 9650 RockvillePike, Bethesda, Md.), Robert A. Day's How To Writeand Publish a Scientific Paper (2nd ed., 1983; ISIPress), and Scientific Writing for Graduate Students(Council of Biology Editors, Inc.), as interpreted andmodified by the editors and the ASM PublicationsDepartment. The editors and the Publications Depart-ment reserve the privilege of editing manuscripts toconform with the stylistic conventions set forth in theaforesaid publications and in these instructions.

The Review ProcessAll manuscripts are subjected to peer review by the

editors, by members of the editorial board, or byqualified outside reviewers. When a manuscript issubmitted to IAI, it is given a manuscript controlnumber and is assigned to one of the editors. Thecorresponding author is notified of this number and theeditor to whom the manuscript is assigned. (It is theresponsibility of the corresponding author to informthe coauthors of the manuscript status throughout thereview and publication processes.) The reviewers op-erate under strict guidelines set forth in "Guidelinesfor Reviewers" and are expected to complete theirreviews within 3 weeks after receipt of the manuscript.Authors are notified, generally within 8 weeks aftersubmission, as to acceptance, rejection, or need formodification. When a manuscript is returned to theauthor for modification, it should be returned to theeditor within 2 months. If more time is required,permission should be obtained from the editor; other-wise it may be considered withdrawn.When an editor has decided that a manuscript is

scientifically acceptable for publication, the manu-script is sent to the ASM Publications Departmenttogether with a signed letter of acceptance. The monthof publication, approximate galley date, and sectionare added to the acceptance letter, and the letter ismailed to the author. The editorial staff of the ASMPublications Department completes the editing of themanuscript to bring it into conformity with prescribedstyle and English usage.

Page ProofsThe printer sends the dummy page proofs (i.e., page

proofs without folios), copy-edited manuscript, andpage charge/reprint order form to the author. As soonas the page proofs are corrected (within 48 h), theyshould be mailed to the ASM Publications Depart-ment.The proof stage is not the time to make extensive

corrections, additions, or deletions. Important newinformation that has become available between ac-ceptance and receipt of the proofs may be inserted asan "Addendum in Proof' with the permission of theeditor. Limit changes to correction of spelling errors,incorrect data, serious grammatical errors, and com-pletion of "in press" references. Such references canbe listed in Literature Cited in alphabetical order byadding "a," "b," etc., to the reference number; i.e., ifthe reference falls after citation 12, give it the designa-tion "12a." Do not renumber references.

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Regular PapersRegular full-length papers should include the ele-

ments described in this section.

Title. Each manuscript should present the results ofan independent, cohesive study; thus, numbered se-ries titles are not permitted. Exercise care in compos-ing a title. Avoid the main-title/subtitle arrangement,complete sentences, and unnecessary articles. On thetitle page, include: title, running title (not to exceed 54characters and spaces), full name (including first nameand middle initial) of each author, address(es) of theinstitution(s) at which the work was performed, andeach author's affiliation or a footnote indicating thepresent address(es) of any author(s) no longer at theinstitution where the work was performed. Place anasterisk after the name of the author to whom inquiriesregarding the paper should be directed, and give thatauthor's telephone number.

Disclaimers. If a statement disclaiming governmen-tal or any other type of endorsement or approval isincluded, it will be deleted by the Publications Depart-ment.

Abstract. Limit the abstract to 250 words or fewer,and concisely summarize the basic content of thepaper without presenting extensive experimental de-tails. Avoid abbreviations, diagrams, and references.When it is essential to include a reference, use the full

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literature citation but omit the article title. Because theabstract will be published separately by abstractingservices, it must be complete and understandablewithout reference to the text.

Introduction. The introduction should supply suffi-cient background information to allow the reader tounderstand and evaluate the results of the presentstudy without referring to previous publications on thetopic. The introduction should also provide the ratio-nale for the present study. Choose references carefullyto provide the most salient background rather than anexhaustive review of the topic.

Materials and Methods. The Materials and Methodssection should include sufficient technical informationso that the experiments can be repeated. When centrif-ugation conditions are critical, give enough informa-tion to enable another investigator to repeat the proce-dure: make of centrifuge, model of rotor, temperature,time at maximum speed, and centrifugal force (x g,rather than revolutions per minute). For commonlyused materials and methods (e.g., commonly usedmedia and protein determinations), a simple referenceis sufficient. If several alternative methods are com-monly employed, it is useful to identify the methodbriefly as well as to cite the reference. For example, itis preferable to state "cells were broken by ultrasonictreatment as previously described (9)" rather than"cells were broken as previously described (9)." Thereader should be allowed to assess the method withoutconstant reference to previous publications. Describenew methods completely, and give sources of unusualchemicals, equipment, or microbial strains. Whenlarge numbers of microbial strains or mutants are usedin a study, include strain tables identifying the sourcesand properties of the strains, mutants, bacteriophages,plasmids, etc.A method, strain, etc., used in only one of several

experiments reported in the paper may be described inthe Results section or, if brief enough (two or threesentences), in a table footnote or figure legend.

Results. In the Results section, include the rationaleor design of the experiments as well as the results;reserve extensive interpretation of the results for theDiscussion section. Present the results as concisely aspossible in one of the following: text, table(s), orfigure(s). However, avoid extensive use of graphs topresent data that might be more concisely presented inthe text or tables. For example, except in unusualcases, double-reciprocal plots used to determine ap-parent Km values should not be presented as graphs;instead, the values should be stated in the text. Simi-larly, graphs illustrating other graphic methods com-monly used to derive kinetic or physical constants(e.g., reduced viscosity plots and plots used to deter-mine sedimentation velocity) need not be shown ex-cept in unusual circumstances. All tabular data mustbe accompanied by either standard deviation values or

standard errors of the means. The number of replicatedeterminations (or animals) used for making suchcalculations also must be included. All statementsconcerning the significance of the differences observedshould be accompanied by probability values given inparentheses. The statistical procedure used should bestated in Materials and Methods. Limit photographs(particularly photomicrographs and electron micro-graphs) to those that are absolutely necessary todemonstrate the experimental findings. Number fig-ures and tables in the order in which they are cited inthe text, and be sure to cite all figures and tables.

Discussion. The Discussion should provide the inter-pretation of the results in relation to previously pub-lished work and to the experimental system at handand should not contain extensive repetition of theResults section or reiteration of the introduction. Inshort papers, the Results and Discussion sections maybe combined.

Acknowledgments. Acknowledgments for financialassistance and for personal assistance are given in twoseparate paragraphs. The usual format for acknowl-edgment of grant support is as follows: "This workwas supported by Public Health Service grant CA-01234 from the National Cancer Institute."

Appendixes. Appendixes, which contain supplemen-tary material to aid the reader, are permitted. Titles,authors, and Literature Cited sections that are distinctfrom those of the primary article are not allowed. If itis not feasible to list the author(s) of the appendix inthe by-line or the Acknowledgment section of theprimary article, rewrite the appendix so that it can beconsidered for publication as an independent article,either full length or Note style. Equations, tables, andfigures should be labeled with the letter "A" preced-ing the numeral to distinguish them from those cited inthe main body of the text.

Literature Cited. The Literature Cited section mustinclude all published work that is relevant. Arrange thecitations in alphabetical order, by first author, andnumber consecutively. (Abbreviate journal names ac-cording to Serial Sources for the BIOSIS Data Base,BioSciences Information Service, 1983.) Cite eachlisted reference by number in the text.The following types of references are not valid for

listing: unpublished data, personal communications,manuscripts in preparation, manuscripts submitted,"in press" references, pamphlets, abstracts, patents,theses, dissertations, and material that has not beensubjected to peer review. References to such sourcesshould be made parenthetically in the text. An "inpress" reference to an ASM publication should statethe control number (e.g., IAI 576) or the name of thepublication, if it is a book.

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Follow the styles shown in the examples below.1. Alderete, J. F., and D. C. Robertson. 1978. Purification

and chemical characterization of the heat-stable entero-toxin produced by porcine strains of enterotoxigenicEscherichia coli. Infect. Immun. 19:1021-1030.

2. Berry, L. J., R. N. Moore, K. J. Goodrum, and R. E.Couch, Jr. 1977. Cellular requirements for enzyme inhibi-tion by endotoxin in mice, p. 321-325. In D. Schlessinger(ed.), Microbiology-1977. American Society for Micro-biology, Washington, D.C.

3. Finegold, S. M., W. E. Shepherd, and E. H. Spaulding.1977. Cumitech 5, Practical anaerobic bacteriology. Co-ordinating ed., W. E. Shepherd. American Society forMicrobiology, Washington, D.C.

4. Gill, T. J., III. 1976. Principles of radioimmunoassay, p.169-171. In N. R. Rose and'H. Friedman (ed.), Manual ofclinical immunology. American Society for Microbiology,Washington, D.C.

5. Leadbetter, E. R. 1974. Order II. Cytophagales nomennovum, p. 99. In R. E. Buchanan and N. E. Gibbons(ed.), Bergey's manual of determinative bacteriology, 8thed. The Williams & Wilkins Co., Baltimore.

6. Miller, J. H. 1972. Experiments in molecular genetics, p.352-355. Cold Spring Harbor Laboratory, Cold SpringHarbor, N.Y.

7. Sacks, L. E. 1972. Influence of intra- and extracellularcations on the germination of bacterial spores, p. 437-442. In H. 0. Halvorson, R. Hanson, and L. L. Campbell(ed.), Spores V. American Society for Microbiology,Washington, D.C.Parenthetical references in the text should be cited

as follows:... and protects the organisms against oxygen toxici-ty (H. P. Misra and I. Fridovich, Fed. Proc. 35:1686,1976).... system was used (W. E. Scowcroft, A. H. Gib-son, and J. D. Pagan, Biochem. Biophys. Res. Com-mun., in press).... in linkage group XIV (R. D. Smyth, Ph.D. thesis,University of California, Los Angeles, 1972).... in poly mitochondria (S. E. Mainzer and C. W.Slayman, Abstr. Annu. Meet. Am. Soc. Microbiol.1976, K15, p. 139).

NotesSubmit Notes in the same way as full-length papers.

They receive the same review, and they are neitherpublished more rapidly than full-length papers norconsidered preliminary communications. The Noteformat is intended for the presentation of brief obser-vations that do not warrant full-length papers.Each Note must have an abstract of no more than 50

words. Do not use section headings in the body of theNote; report methods, results, and discussion in asingle section. Paragraph lead-ins are permissible. Thetext is not to exceed 1,000 words, and the number offigures and tables should be kept to a minimum.Materials and methods should be described in the text,not in figure legends or table footnotes. Present ac-knowledgments as in full-length papers, but do not usea heading. The Literature Cited'section is identical tothat of full-length papers.

ErrataThe Erratum section provides a means of correcting

errors (e.g., typographical) in previously publishedarticles. Changes in data and addition of new materialare not permitted.Send errata directly to the Publications Department.

Author's CorrectionsThe Author's Correction section provides a means

of adding citations that were overlooked in a previous-ly published article. The author who failed to cite areference and the author whose paper was not citedmust agree to such a publication; the editor, editor inchief, chairman of the Publications Board, and direc-tor of Publications will not be involved. Letters fromboth authors must accompany the author's correctionsent to the Publications Department.

ILLUSTRATIONS AND TABLESHalftone PhotographsWhen submitting halftone photographs (e.g., poly-

acrylamide gels), keep in mind the journal page size:35/16 inches for a single column and 67/8 inches for adouble column (maximum). Include only the signifi-cant portion of the illustration. Each must be ofsufficient contrast to withstand the inevitable loss ofcontrast and detail inherent in the printing process.Submit two photographs of each figure; photocopiesare not acceptable. If possible, submit figures the samesize as they are to be published. If they must bereduced, make sure that all elements, including label-ing, can withstand reduction and remain legible. If afigure is a composite of a halftone and a drawing orlabeling, the halftone should be mounted on the origi-nal drawing (i.e., do not submit a photograph of thecomposite).

Electron and light micrographs must be first-genera-tion copies of the original negative; in addition to thetwo sets of photographs for the reviewers, include aset to be used for reproduction. Indicate the magnifica-tion with a scale marker on each micrograph. Figuresmay be mounted on bond paper or on lightweight,flexible board; do not mount them on heavy card-board.

Color PhotographsColor photographs are discouraged. However, if

they are necessary, include three copies so that a costestimate for printing may be obtained. The cost ofprinting color photographs must be borne by theauthor.

DrawingsSubmit graphs, charts, diagrams, and other draw-

ings as photographs made from finished drawings notrequiring additional artwork or typesetting. No part ofthe graph or drawing should be typewritten or handlettered. Use a lettering set or other professional-quality device for all labeling. Most graphs will be

iv


reduced to a one-column width (35/16 inches), and allelements in the drawing should be prepared to with-stand this reduction. Avoid heavy letters, which tendto close up when reduced, and unusual symbols,which the printer may not be able to reproduce in thelegend. Direct readouts from computers, recorders,etc., are not usually acceptable; such material shouldbe redrawn. One of the two sets of drawings may

consist of photocopies; the other, however, mustconsist of photographs.

In figure ordinate and abscissa scales (as well as intable column headings), avoid ambiguous use of num-bers with exponents. Usually, it is preferable to use

the International System of Units (,u for 10-6, m for10-3, k for 103, M for 106, etc.). A complete listing ofSI symbols can be found in the International Union ofPure and Applied Chemistry (IUPAC) "Manual ofSymbols and Terminology for Physicochemical Quan-tities and Units" (Pure Appl. Chem. 21:3- 44, 1970).Thus, a representation of 20,000 cpm on a figureordinate is to be made by the number 20, accompaniedby a label kcpm.When powers of 10 must be employed, the editorial

style of IAI follows the CBE Style Manual recommen-dation, which differs in the convention employed fromthat of several other journals. The CBE Style Manualsuggests that the exponent power be associated withthe number shown. In representing 20,000 cells per ml,the numeral on the ordinate would be "2" and thelabel would be "i04 cells per ml" (not "cells per ml x10-4"). Likewise, an enzyme activity of 0.06 U/mlwould be shown as 6, accompanied by the label 10-2

U/ml. The preferred designation would be 60 mU/mllabeled as mU (or milliunits) per ml.

Figure LegendsLegends should provide enough information so that

the figure is understandable without frequent refer-ence to the text. However, detailed experimentalmethods must be discussed in the Materials and Meth-ods section, not in a figure legend. A method that isunique to one of several experiments may be reportedin a legend only if the discussion is very brief (two orthree sentences). Define all symbols and abbreviationsused in the figure. Common abbreviations and othersused frequently in preceding text need not be rede-fined in the legend.

TablesType each table on a separate page. Arrange the

data so that columns of like material read down, notacross. The headings should be sufficiently clear sothat the meaning of the data will be understandablewithout reference to the text. See the Abbreviationssection of these instructions for those that may be usedin tables. Explanatory footnotes are acceptable, butmore extensive table "legends" are not. Footnotesshould not include detailed descriptions of the experi-ment. A well-constructed table is shown below.

TABLE 1. Trapping of previously perfused piliated S. ty-phimurium by mouse livers

% Recovery in':Bacteria Total

Liver Perfusate recovery

Control 60.1 ± 11.2 46.2 ± 10.5 106.2 ± 8.7Previously 39.4 8.4b 66.2 ± 9.5b 105.6 ± 10.3

perfused

a Mean ± standard deviation of at least seven experi-ments.

b p < 0.001 versus control by the White rank ordermethod (21).

Camera-Ready CopyDrawings, tables, chemical formulas, etc., that can

be photographically reproduced for publication with-out further typesetting or artwork are referred to as"camera ready." Such copy may also be prepared forcomplicated mathematical or physical formulas, por-tions of genetic maps, diagrams, and flow schemes. Itshould not be hand lettered. Camera-ready copy mustbe carefully prepared to conform with the style of IAI.The advantage to submitting camera-ready copy is thatthe material will appear exactly as enyisioned by theauthor, and no second proofreading is necessary. Thisis particularly advantageous when there are long,complicated tables and when the division of materialand spacing are important.

NOMENCLATURE

Chemical and Biochemical NomenclatureThe recognized authority for the names of chemical

compounds is Chemical Abstracts (Chemical AbstractService, Ohio State University, Columbus) and itsindexes. For biochemical terminology, including ab-breviations and symbols, consult the following: Inter-national Union of Biochemistry Biochemical Nomen-clature and Related Documents (1978; reprinted forThe Biochemical Society, London, England), instruc-tions to authors of the Journal ofBiological Chemistryand Archives of Biochemistry and Biophysics (firstissues of each year), and the Handbook ofBiochemis-try and Molecular Biology (G. D. Fasman, ed., CRCPress, Inc., 3rd ed., 1976).Do not express molecular weight in daltons; molecu-

lar weight is a unitless ratio. Molecular mass is ex-pressed in daltons.For enzymes, use the recommended (trivial) name

assigned by the Nomenclature Committee of the Inter-national Union of Biochemistry as described in En-zyme Nomenclature 1978 (Academic Press, Inc.,1979). If a nonrecommended name is used, place theproper (trivial) name in parentheses at first use in theabstract and text. Use the EC number when it hasbeen assigned, and express enzyme activity either inkatals (preferred) or in the older system of ",umol/min."

v


DrugsWhenever possible, use generic names rather than

trade names of drugs.

Nomenclature of MicroorganismsBinary names consisting of a generic name and a

specific epithet (e.g., Escherichia coli) should be usedfor all microorganisms. Names of higher categoriesmay be used alone, but a specific epithet must bepreceded by a generic name the first time it is used in apaper. Thereafter, the generic name should be abbre-viated to the initial capital letter (e.g., E. coli), provid-ed there can be no confusion with other genera used inthe paper. Names of all taxa (phyla [for fungi, divi-sions], classes, orders, families, genera, species, andsubspecies) are printed in italics; strain designationsand numbers are not.The spellings of bacterial names should follow those

presented in Bergey's Manual ofDeterminative Bacte-riology (8th ed., The Williams & Wilkins Co., 1974).The names in the Approved Lists of Bacterial Names(American Society for Microbiology, 1980) and thesubsequent validation lists published in the Interna-tional Journal of Systematic Bacteriology have taxo-nomic precedence over those published in Bergey'sManual. If there is reason to use a name that does nothave standing in nomenclature, the name should beenclosed in quotation marks and an appropriate state-ment concerning the nomenclature status of the nameshould be made in the text (for an example, see Int. J.Syst. Bacteriol. 30:547-556, 1980).

It is recommended that a strain be deposited in arecognized culture collection when that strain is neces-sary for the description of a new taxon (see Bacterio-logical Code, 1975 Revision, American Society forMicrobiology, 1975).

Since the classification of fungi is far from complete,it is the responsibility of the author to determine thecurrently accepted binomial for a given yeast or mold.Some sources for the spelling of these names includeThe Yeasts (J. Lodder, ed., North-Holland PublishingCo., 1970) and Ainsworth and Bisby's Dictionary ofthe Fungi, Including the Lichens, 6th ed. (Common-wealth Mycological Institute, Kew, Surrey, England,1971).Microorganisms, viruses, and plasmids should be

given designations consisting of letters and serial num-bers. It is generally advisable to include a worker'sinitials or a descriptive symbol of locale, laboratory,etc., in the designation. Each new strain, mutant,isolate, or derivative should be given a new (serial)designation. Such a designation should be distinctfrom those of the genotype and phenotype, and geno-typic and phenotypic symbols should not be included.A registry of plasmid designations is maintained by

the Plasmid Reference Center, Department of MedicalMicrobiology, Stanford University, Stanford, CA94305.

Genetic Nomenclature

Bacteria. The genetic properties of bacteria aredescribed in terms of phenotypes and genotypes. Thephenotype designation describes the observable prop-erties of an organism. The genotype refers to thegenetic constitution of an organism, usually in refer-ence to some standard wild type. Use the recommen-dations of Demerec et al. (Genetics 54:61-74, 1966) asa guide in employing these terms. If your manuscriptcontains information including genetic nomenclature,please refer to the Instructions to Authors in the Janu-ary issue of the Journal of Bacteriology.

"Mutant" vs. "mutation." Keep in mind the distinc-tion between a mutation (an alteration of the primarysequence of the genetic material) and a mutant (astrain carrying one or more mutations). One mayspeak about the mapping of a mutation, but one cannotmap a mutant. Likewise, a mutant has no geneticlocus-only a phenotype.

Transposable elements, plasmids, and restriction en-zymes. Nomenclature of transposable elements (inser-tion sequences, transposons, phage Mu, etc.) shouldfollow the recommendations of Campbell et al. (Gene5:197-206, 1979), with the modifications given in sec-tion vi. The system of designating transposon inser-tions at sites where there are no known loci, e.g., zef-123::Tn5, has been described by Chumley et al. (Ge-netics 91:639-655, 1979). Whenever possible, use thenomenclature recommendations of Novick et al. (Bac-teriol. Rev. 40:168-189, 1976) for plasmids and plas-mid-specified activities, of Low (Bacteriol. Rev.36:587-607, 1972) for F-prime factors, and of Roberts(Nucleic Acids Res. 9:r75-r96, 1981) for restrictionenzymes and DNA fragments derived from treatmentwith these enzymes. Recombinant DNA molecules,constructed in vitro, follow the nomenclature for in-sertions in general. DNA inserted into recombinantDNA molecules should be described by using the genesymbols and conventions for the organism from whichthe DNA was obtained. The Plasmid Reference Cen-ter, Stanford University School of Medicine, assignsTn and IS numbers in such a fashion as to avoidconflicting and repetitive use.

ABBREVIATIONS AND CONVENTIONS

Verb TenseUse the past tense to narrate particular events in the

past, including the procedures, observations, and dataof the study you are reporting. Use the present tensefor general statements, including your own generalconclusions, conclusions of previous researchers, andgenerally accepted facts. In addition, the present tenseshould be used for discourse having an immediateeffect on the reader ("the data indicate"; "Fig. 1shows").

Vi


AbbreviationsGeneral. It is strongly recommended that all abbre-

viations except those listed below be introduced in thefirst paragraph in Materials and Methods. Alternative-ly, define each abbreviation and introduce it in paren-theses the first time it is used; e.g., "cultures weregrown in Eagle minimal essential medium (MEM)."Generally, eliminate abbreviations that are not used atleast five times in the text (including tables and figurelegends). Abbreviations should be used primarily as anaid to the reader, rather than as a convenience to theauthor, and therefore their use should be limited.Abbreviations other than those recommended by theIUPAC-IUB (Biochemical Nomenclature and RelatedDocuments, 1978) should be used only when a casecan be made for necessity, such as in tables andfigures.

It is often possible to use pronouns or to paraphrasea long word after its first use (e.g., "the drug," "thesubstrate"). Standard chemical symbols, numericalmultiples (e.g., Me2SO for dimethyl sulfoxide), andtrivial names or their symbols (folate, Ala, Leu, etc.)may be used for terms that appear in full in theneighboring text.Not requiring introduction. In addition to abbrevia-

tions for standard units of measurement and chemicalsymbols of the elements, the following should be usedwithout definition in the title, abstract, text, figurelegends, and tables: DNA (deoxyribonucleic acid);cDNA (complementary DNA); RNA (ribonucleicacid); RNase (ribonuclease); DNase (deoxyribonucle-ase); rRNA (ribosomal RNA); mRNA (messengerRNA); tRNA (transfer RNA); AMP, ADP, ATP,dAMP, GTP, etc. (for the respective 5' phosphates ofadenosine or other nucleosides); ATPase, dGTPase,etc. (adenosine triphosphatase, deoxyguanosine tri-phosphatase, etc.); 2'-AMP, 3'-AMP, and 5'-AMP (the2'-, 3'-, and 5'-, when needed for contrast, phosphatesof the nucleosides); NAD+ (nicotinamide adenine di-nucleotide, oxidized); NADH (nicotinamide adeninedinucleotide, reduced); NADP (nicotinamide adeninedinucleotide phosphate); NADPH (nicotinamide ade-nine dinucleotide phosphate, reduced); Pi (orthophos-phate); PP1 (pyrophosphate); UV (ultraviolet); PFU(plaque-forming units); CFU (colony-forming units);MIC (minimal inhibitory concentration); MBC (mini-mal bacterial concentration); Tris [tris(hydroxymeth-yl)aminomethane]; DEAE (diethylaminoethyl); andEDTA (ethylenediaminetetraacetate). Abbreviationsfor cell lines (e.g., HeLa cells) also need not bedefined.The following abbreviations should be used without

definition in tables:amt (amount)approx (approximately)avg (average)concn (concentration)diam (diameter)expt (experiment)

SE (standard error)SEM (standard error of themean)

sp act (specific activity)sp gr (specific gravity)temp (temperature)

ht (height)mo (month)mol wt (molecular

weight)no. (number)prepn (preparation)SD (standard deviation)

tr (trace)vol (volume)vs (versus)wk (week)wt (weight)yr (year)

Reporting Numerical DataStandard metric units are used for reporting length,

weight, and volume. For these units and for molarity,use the prefixes m, ,u, n, and p (for i0-', 10-6, 10-9,and 10-12, respectively). Likewise, use the prefix k(for 103). Avoid compound prefixes such as mp. or RR,.Use ,ug/ml or ,ug/g in place of the ambiguous ppm.Units of temperature are presented as follows: 37°C or342 K.When fractions are used to express units such as

enzymatic activities, it is preferable to use wholeunits, such as g or min, in the denominator instead offractional or multiple units such as jig or 10 min. Forexample, "pmol/min" would be preferable to "pmol/10 min," and ",umol/g" would be preferable to "nmol/,ug." It is also preferable that an unambiguous formsuch as exponential notation be used in place ofmultiple slashes; for example, ",umol g-1 min-1" ispreferable to ",umol/g per min."See the CBE Style Manual, 5th ed., for more

detailed information regarding the reporting of num-bers. Also contained in this source is information onthe appropriate SI units to be used for the reporting ofillumination, energy, frequency, pressure, and otherphysical terms. Always report numerical data in theappropriate SI unit.

Isotopically Labeled CompoundsFor simple molecules, labeling is indicated in the

chemical formula (e.g., 14Co2, 3H20, H235S04).Brackets are not employed when the isotopic symbolis attached to a word which is not a specific chemicalname (e.g., 1311-labeled protein, 14C-amino acids, 3H-ligands, etc.).For specific chemicals, the symbol for the isotope is

placed in square brackets directly preceding the part ofthe name that describes the labeled entity. Note thatconfiguration symbols and modifiers precede the iso-topic symbol. The following examples illustrate cor-rect usage:[14C]urea UDP-[U-14C]glucoseL-[methyl-14C]methionine E. coli [32P]DNA[2,3-3H]serine fructose 1,6[1-32P]bisphosphate[a-14C] ysine[-_32P]ATP

This journal follows the same conventions forisotopic labeling as the Journal ofBiological Chemis-try, and more detailed information can be found in theinstructions to authors of that journal (first issue ofeach year).

.ii

1984 Full MembershipAmerican Society for Microbiology

1913 I St., NW, Washington, DC 20006

The Society welcomes to full membership any person who is interested in its objects, and who holds a bachelor's degree in

microbiology or a related field (or who has had training and experience equivalent to that represented by a bachelor's degree).The minimum annual membership assessment is $50, which includes a general membership fee, ASM News, and $41 toward

subscriptions to the Society's scientific journals. The Society publishes nine scientific journals (listed below). Members may

subscribe to one or more of these journals at special member rates; $41 of the minimum dues payment of $50 may be creditedtowards journal subscriptions. In addition, the Society publishes the monthly ASM News, which is sent to all members andcontains news and announcements of interest to all microbiologists.Memberships are initiated and renewed as of January each year. Unles there are directions to the contrary, membership

nominations received prior to November 1 will be credited to the current year, and back issues of the selected publications forthe current year will be furnished. Nominations received after November 1 will become effective the following January.

First Name Initial Last Name

Address

Area Code

City State Zip Code Phone No.

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Signature of Nominee

Nominated by(Signature of Society member)

I. 1. Journals may be subscribed to at the following rates. Please enter thehigher rate (column B) if you reside outside the U.S. and its possessions.

A B

Journal of Bacteriology UB).$37 $49Antimicrobial Agents and Chemotherapy (AA).$31 $41

Applied and Environmental Microbiology (AE).$32 $42

International Journal of Systematic Bacteriology (IJ).$27 $27

Journal of Virology (JV) ........... ................................. $37 $49

Journal of Clinical Microbiology UC) ....... ......................... $31 $41

Microbiological Reviews (MR) ......... ............................. $16 $26

Infection and Immunity (IA) ......... .............................. $37 $49

Molecular and Cellular Biology (CB) ....... ......................... $27 $35

2. Membership Fee (includes ASM News) ..................... ........................ $ 9.00

3. Total dues and journals from lines 1 and 2 (MINIMUM PAYMENT $50)... $II. Ol Check this block if you prefer to receive only ASM News and remit $50.

RATES ARE FOR 1984 ONLY

Please enclose payment with application.

Prices are listed in U.S. dollars. Due to currency exchange difficulties and cost, foreign applicants in countriesexcept Canada must remit in U.S. dollars by check or draft (payable to ASM) drawn on a U.S. bank located withinthe continental United States. Applicants from Canada may use checks drawn on Canadian banks, but remittancemust be made in U.S. dollars.

The American Academy of Microbiology (AAM), the professional arm of theAmerican Society for Microbiology, initiated voluntary certification programs20 years ago. These programs are now independently administered by theNational Registry of Microbiologists, the American Board of Medical Microbiologyand the American Board of Medical Laboratory ImmLunology. Through rigorousexamination processes, employers of certified individuals are assured ofprofessional competence.

PROFESSIONALS: INVESTIGATE THE OPPORTUNITY TODEMONSTRATE YOUR COMPETENCEAND ENHANCE YOUR CREDENTIALS

EMPLOYERS: DISCOVER THE ADVANTAGES OFHIRING CERTIFIED PROFESSIONALS

NATIONAL REGISTRY OF MICROBIOLOGISTSCertification following successful completion of a written examination byqualified microbiologists at the baccalaureate, masters and doctorate level.

AMERICAN BOARD OF MEDICAL MICROBIOLOGYCertification in public health and medical microbiology, mycology,parasitology or virology following successful completion of a thoroughwritten and oral examination by microbiologists completing an AAM approvedpostdoctoral training program or an approved preceptorship.

AMERICAN BOARD OF MEDICAL LABORATORY IMMUNOLOGYCertification in medical laboratory immunology following successfulcompletion of a thorough written and oral examination by qualifiedimmunologists completing acceptable postdoctoral training and experience.

For Information,Contact: CERTIFICATION PROGRAMS

c/o American Society for Microbiology1913 Street, NWWashington. DC 20006

p-

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0 m

1984 Student MembershipAmerican Society for Microbiology

1913 I St., NW, Washington, DC 20006

Any regularly matriculated student majoring in microbiology or a related field is eligible for election as a Student Member.

Student Members have all privileges of membership except the right to vote and hold office in the Society.Student Members receive the monthly ASM News and are entitled to subscribe to the Society's journals at member rates.

Memberships are initiated and renewed in January of each year. Unless there are directions to the contrary, membership

nominations received prior to November 1 will be credited to the current year, and back issues of the selected publications for

the current year will be furnished if available. Nominations received after November 1 will become effective the followingJanuary.

ADDRESS

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* Nominated by: (1)

(Society members) (2)

* If the department chairman is a member of the Society, only one additional nominating signature is required.

1. Journals may be subscribed to at the following rates. Please enter thehigher rate (column B) if you reside outside the U.S. and its possessions.

Journal of Bacteriology (B) .........................................Antimicrobial Agents and Chemotherapy (AA) .......................Applied and Environmental Microbiology (AE) .......................International Journal of Systematic Bacteriology (IJ) ...................Journal of VirologyUV).Journal of Clinical Microbiology JC).Microbiological Reviews (MR) ......................................Infection and Immunity (IA) .......................................Molecular and Cellular Biology (CB) ................................

A BL II$37 $49$31 $41$32 $42$27 $27$37 $49$31 $41$16 $26$37 $49$27 $35

2. Dues (includes ASM News) ..................... $ 5.00

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RATES ARE FOR 1984 ONLY

Please enclose payment with application.

Prices are listed in U.S. dollars. Due to currency exchange difficulties and cost, foreign applicants in countriesexcept Canada must remit in U.S. dollars by check or draft (payable to ASM) drawn on a U.S. bank located withinthe continental United States. Applicants from Canada may use checks drawn on Canadian banks, but remittancemust be made in U.S. dollars.