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© 2018 Align Technology, Inc. 1 Incredible Platform for Continued Growth / JOE HOGAN President and Chief Executive Officer / New York, May 23, 2018

Incredible Platform for Continued Growth

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© 2018 Align Technology, Inc. 1

Incredible Platformfor Continued Growth

/ JOE HOGANPresident and Chief Executive Officer

/ New York, May 23, 2018

© 2018 Align Technology, Inc. 2© 2018 Align Technology, Inc. 2

Forward Looking Statement

During this presentation and corresponding commentary we may make forward-looking

statements, including statements regarding Align’s strategy for future growth, plans related to

global expansion of operational presence, our expectations regarding our ability to develop and

commercialize new products, planned geographic expansion and anticipated impact on our

growth, our expectations related to sales force coverage on, among other things, customer

adoption, as well as statements related to Align’s business outlook for 2018 and beyond. Any such

forward-looking statements contained in this presentation and corresponding commentary are

based upon information available to Align as of the date hereof. These forward-looking statements

are only predictions and are subject to risks, uncertainties and assumptions that are difficult to

predict. As a result, actual results may differ materially and adversely from those expressed in any

forward-looking statement. Factors that may cause such a difference include, but are not limited to,

the factors that are discussed in more detail in Align Technology’s Forms 10-K and 10-Q, as well

as in other reports and documents filed from time to time with the Securities and Exchange

Commission. Align undertakes no obligation to revise or update publicly any forward-looking

statements for any reason.

© 2018 Align Technology, Inc. 3

Align Tech

Invisalign FDA

US Ortho

Consumer Ad

IPO

Europe

US GPs

NYU Dental School

Express 10 APAC Dist

Vivera

Invisalign TeenEMEA Dist

Invisalign G3

Cadent iTero

Invisalign G4

Invisalign G5

SmartTrackMaterial

APAC Direct

Express 5

ClinCheck Pro

EMEA Direct

Invisalign G6

China

iTero Element

India

Japan

Invisalign G7

Invisalign G6 iTero

Timelapse

Invisalign with Mandibular Advancement

1M Patients

2M Patients

3M Patients

4M Patients

100 Patients

$500 MILLION

$100 MILLION

$1.5 BILLION

5M Patients

We’re Just Startingto Hit Our Stride

© 2018 Align Technology, Inc. 4© 2018 Align Technology, Inc. 4

REVENUE GROWTH +$600MOperating Income

3.5XiTero Scanners

+1.6M Invisalign Cases

+38K Invisalign Doctors

2 YearGrowth

© 2018 Align Technology, Inc. 5© 2018 Align Technology, Inc. 5

CONVERGENCE

Demand Technology

Capability

© 2018 Align Technology, Inc. 6© 2018 Align Technology, Inc. 6

MARKET EXPANSION

© 2018 Align Technology, Inc. 7

Bring Clear AlignerOrthodontic Treatmentto the Masses

/ VISION

© 2018 Align Technology, Inc. 8© 2018 Align Technology, Inc. 8

Worldwide

Annual Cases

© 2018 Align Technology, Inc. 9

Worldwide

Annual Cases

4MAPAC

4MEMEA

4MAmericas

© 2018 Align Technology, Inc. 10© 2018 Align Technology, Inc. 10© 2018 Align Technology, Inc. 10

MILLIONWORLDWIDE

© 2018 Align Technology, Inc. 11© 2018 Align Technology, Inc. 11

Built ForDoctors& Consumers

100% DigitalApproach

GlobalScale

UnrivaledExperience

© 2018 Align Technology, Inc. 12© 2018 Align Technology, Inc. 12

© 2018 Align Technology, Inc. 13

YEARS

© 2018 Align Technology, Inc. 13

100% Digital Approach

Digital Scanning

Software Applications

Big Data Analytics

Machine Learning

Virtual Treatment Plans

© 2018 Align Technology, Inc. 14© 2018 Align Technology, Inc. 14

AlignersRetainersExpanders

SmartTrackMaterial

SmartForceAttachmentsand Features

SmartStageProgrammed Tooth

Movement

ClinCheck Pro

iTeroScanner

InvisalignOutcome Simulator

100% Digital Technology

© 2018 Align Technology, Inc. 15© 2018 Align Technology, Inc. 15© 2018 Align Technology, Inc. 15

GlobalScale

© 2018 Align Technology, Inc. 16© 2018 Align Technology, Inc. 16

Order Acquisition & Manufacturing Operations

SAN JOSE,COSTA RICA

Order Acquisition

ZIYANG, CHINA(2H 2018)

JUAREZ, MEXICO

COLOGNE,GERMANY

MADRID, SPAIN(2H 2018)

CHENGDU, CHINA

AMSTERDAM

Treatment Planning

Countries

103Trained Doctors

136KSalesMarketing

1KMfg. & CAD/CAMDesigners

4K

GlobalScale

© 2018 Align Technology, Inc. 17© 2018 Align Technology, Inc. 17

Brand AdvantageHighest consumer

and doctor awareness

Doctor AdvantageLargest network of

trained doctors

IP Advantage880 patents

Data AdvantageData and insights from

5.5 Million patients

Operational AdvantageLargest global reach

Go To Market AdvantageLargest and most

experienced salesforce

© 2018 Align Technology, Inc. 17

© 2018 Align Technology, Inc. 18© 2018 Align Technology, Inc. 18

Strategic Focusand Execution

InternationalExpansion

OrthodontistUtilization

GP DentistTreat & Refer

PatientDemand &Conversion

© 2018 Align Technology, Inc. 19

Our Unique Opportunityis Enormous

© 2018 Align Technology, Inc. 20