scientific committee

Paolo A. Ascierto

Ruggero Ridolfi

Carlo Riccardo Rossi

Alessandro Testori

Giusto Trevisan

Andrea Veronesi

Ministero della SaluteIstituto Superiore di Sanità

Regione Friuli Venezia GiuliaFederazione Regionale Ordine dei Medici ChirurghiComune di Grado

Università degli Studi di TriesteFacoltà di Medicina e Chirurgia - Università degli Studi di Trieste

AREA Science Park

A.I.O.M. Associazione Italiana di Oncologia MedicaA.I.I.O. Associazione Italiana Infermieri di OncologiaL.I.L.T. Lega Italiana per la Lotta contro i TumoriS.I.C.O. Società Italiana di Chirurgia Oncologica

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Thursday, November 3, 2005Room AQUILEIA

10.30 IMI Scientific Committee Meeting15.30 IMI General AssemblyRoom GRADO

16.30 Opening Ceremony

17.00 - 19.00MITTELEUROPEAN SYMPOSIUM ON MELANOMANational Approaches TowardsMelanoma: Organization ModelsChair: G. Trevisan (Trieste - Italy),A. Veronesi (Aviano - Italy)

17.00 What impact of pigmented lesion clinics inmelanoma screening?B. Giannotti (Florence - Italy)

17.15 Euro melanoma day campaign in SlovakRepublic and solar behaviorof the populationV. Hegyi (Bratislava - Slovak Republic)

17.30 Epidemiology and risk factorsfor melanomas in CroatiaJ. Lipozen@iæ (Zabgreb - Croatia)

17.45 A report on the organization of medical careof melanoma patients in SloveniaN. Glumac (Ljubljana - Slovenia)

18.00 Melanoma care in the Veneto Region:organizational aspects and programmesC. R. Rossi (Padua - Italy)

18.15 Melanoma care in SwitzerlandR. Dummer (Zurich - Switzerland)

Welcome Cocktail

Friday, November 4, 2005Room GRADO

8.30 -11.00Basic Research and New TechnologiesChair: G. Palmieri (Sassari - Italy),M.C. Montesco (Padua - Italy)

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8.30 Circulating endothelial cells as predictors ofanti-angiogenic responseF. Bertolini (Milan - Italy)

8.45 Hereditary melanoma in ItalyG. Bianchi-Scarrà (Genoa - Italy)

9.00 Inhibition of O6-alkylguanine - DNA alkyltransferase byTemozolomide to enhance the antitumor activity of FotemustineM. D’Incalci (Milan - Italy)

9.15 C.T.-P.E.T. in diagnosis and staging of melanomaO. Geatti (Udine - Italy)

9.30 RaLP, a novel Shc family’s member,is involved in the melanoma progressionL. Lanfrancone (Milan - Italy)

9.45 The role of histone deacetylasesin melanoma and solid tumorsS. Minucci (Milan - Italy)

10.00 Activation of endogenous anti-melanomaspecific T cell responsesM. Rescigno (Milan - Italy)

10.15 Dendritic cell vaccination: in vitro and in vivo monitoringA. Riccobon (Forlì - Italy)

10.30 Electrochemotherapy for local tumour control.Results of the ESOPE European trialL. M. Mir (Villejuif - France)

Rapporteur: G. Stanta (Trieste - Italy)

11.00 - 13.00Round Table: Dermatology and Telediagnosis

Chair: H. Kerl (Graz - Austria), R. Bono (Rome - Italy)

11.00 Teledermatology - first experimental experiencesH. P. Soyer (Graz - Austria)

11.15 The second opinion in the borderline melanocytic lesions.The role of thelepathologyG. Botti (Naples - Italy)

11.30 Diagnosis of melanoma without contact with the patient:what’s the risk?P. Carli (Florence - Italy)

11.45 Metastatic melanoma of unknown primary siteA. Gatti (Trieste - Italy)

12.00 Dermoscopic features for difficult melanomasM. A. Pizzichetta (Aviano - Italy)

12.15 Clinical and pathological backgroundof nevus-like melanomaI . Stanganelli (Ravenna - Italy)

12.30 The melanoma databaseat the European Institute of Oncology (EIO)G. Tosti (Milan - Italy)

Rapporteur: G. Trevisan (Trieste - Italy)

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Room AQUILEIA

9.00 - 13.00Surgery

Chair: F. Di Filippo (Rome - Italy), M. Schiavon (Udine - Italy), A.Testori (Milan - Italy)

9.00 The Rotterdam experience with 100 TNF+Melphalan basedIsolated Limb Perfusions (ILP) in patients with multiple mela-noma in transit metastasesA. Eggermont (Rotterdam -The Netherlands)

9.30 Surgery in Stage IV: the influenceof the Cancervax trial on the surgical approachC. Caracò (Naples - Italy)

9.50 In transit metastases: infusion vs perfusionF. De Cian (Genoa - Italy)

10.10 Sentinel node biopsy under local anaesthesiaG. Lazzaro (Milan - Italy)

10.30 Melanoma of the head and neckG. Macripò (Turin - Italy)

10.50 Histopathological examination of sentinel lymph nodesin cutaneous melanoma and prevalenceof additional metastasesG. Mazzarol (Milan - Italy)

11.10 Sentinel lymph node biopsy does not changemelanoma-specific-survival in patientswith Breslow thicker than 4 mm N. Mozzil lo (Naples - Italy)

11.30 Role of surgery in the treatment of metastatic melanoma M. Roseano (Trieste - Italy)

11.50 Role of surgery in the treatment of metastatic melanomaG. M. Verdecchia (Forlì - Italy)

12.10 The prognostic implications of locationfor scalp melanomaE. Fraccalanza (Udine - Italy)

12.30 Management of lymph node metastasesin melanoma patientsC. R. Rossi (Padua - Italy)

Rapporteur: M. Foletto (Padua - Italy)

Room LAGUNA

9.00 - 10.30Advanced Melanoma

Chair: A. Veronesi (Aviano - Italy), R. Ridolfi (Forlì - Italy)

9.00 Advanced melanoma: can we move on ?V. Chiarion Sileni (Padua - Italy)

9.15 Fotemustine plus dacarbazine with or without interferon. TheSICOG trialsG. Comella (Naples - Italy)

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9.30 Melanoma vaccine between dream and realityM. Guida (Bari - Italy)

9.45 What is there beyond chemo-immunotherapyfor metastatic melanoma patients?A. Romanini (Pisa - Italy)

10.00 Independent clinical researchG. L. De Salvo (Padua - Italy)

Rapporteur: A. Freschi (Aviano - Italy)

10.30 - 12.00

GIDO (SIDEMaSt) Group Meeting

M. G. Bernengo (Turin - Italy)

12.00 - 13.00

Free Communications

Chair: V. De Pangher Manzini (Gorizia - Italy), G. Moise (Gorizia - Italy)

12.00 Sentinel lymph node and melanoma: Aviano experienceA. Cattelan (Aviano - Italy)

12.10 Fotemustine in the front line treatmentof stage IV melanoma: pros and consF. Prignano (Florence - Italy)

12.20 Primary prevention campaign for malignant melanoma.A four-year study by AIDA F. Bertolini (Rovigo - Italy)

12.30 Hypertermic antiblastic perfusion with TNF alfaand melphalan in the treatment of limb melanomaV. Patrizi (Rome - Italy)

12.40 Role of sentinel lymph node biopsy in patientswith primary melanoma: results of a multicentric studyA. Vespa (Rome - Italy)

12.50 Insulin-like growth factor system gene expression in patientswith type 2 diabetes and skin cancerC. Colli (Trieste - Italy)

13.00 - 14.00Lunch

Room GRADO

14.00 - 15.00

Plenary Lecture

Chair: P.A. Ascierto (Naples - Italy)

Neoadjuvant therapy with high-dose interferon Alfa-2b

J. Kirkwood (Pittsburgh - USA)

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15.00 - 17.00

Round Table: Follow-up and Adjuvant Treatment

Chair: A. Paccagnella (Venice - Italy), M. Guida (Bari - Italy)

15.00 Prognostic role of melanoma follow-up and treatment appro-ach. A prospective randomised studyat a multi step levelA. Testori (Milan - Italy)

15.20 The follow-up of melanoma:from theory to a practical applicationP. Boggio (Novara - Italy)

15.40 IFN and beyond IFN M. G. Bernengo (Turin - Italy)

16.00 Management and recommendations on toxicitiesfrom adjuvant high-dose interferonA. Romanini (Pisa - Italy)

16.20 EORTC trialsA. Testori (Milan - Italy), A. Eggermont (Rotterdam - The Netherlands)

16.40 Imiquimod and melanoma in situI . H. Wolf (Graz - Austria)

Rapporteur: A. Paccagnella (Venice - Italy)

17.00 - 18.30

Photoprotection

Chair: P. Patrone (Udine - Italy), P. F. Zampieri (Merano - Italy)

17.00 Introduction P. Patrone (Udine - Italy)

17.10 Skin and/vs. Sun: relationship, effects, damagesP. Zampieri (Merano - Italy)

17.30 Photobiology of melanomaA.M. Manganoni (Brescia - Italy), P. Calzavara-Pinton (Brescia - Italy)

18.00 Sun protection: principles andcurrent scientific knowledge W. Wallnöfer (Bolzano - Italy)

Room AQUILEIA

15.00 - 16.00

Histopathology

Chair: H. Kerl (Graz - Austria), M. Pippione (Turin - Italy)

15.00 Melanocytic proliferations:new concepts and observationsH. Kerl (Graz - Austria)

15.30 Malignant blue nevusM. Pippione (Turin - Italy)

Rapporteur: M. Pippione (Turin - Italy)

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16.00 - 18.30ImmunologyChair: P. A. Ascierto (Naples - Italy), M. Maio (Siena - Italy)

16.00 Local immunotherapy in melanoma using gene transferR. Dummer (Zurich - Switzerland)

16.15 The molecular nature of melanoma antigensC. Castell i (Milan - Italy)

16.30 Epigenetic modulation of human melanoma:immunotherapeutic implicationsM. Maio (Siena - Italy)

16.45 Active immunotherapy in melanoma patientswith autologous dendritic cells pulsedwith natural tumor peptidesM. P. Protti (Milan - Italy)

17.00 Immunologic targets and approachesfor future development in melanomaP. Queirolo (Genoa - Italy)

17.15 Cancer immunotherapy based on Salmonellatyphimurium as infectious agentM. Rescigno (Milan - Italy)

17.30 Dendritic cell vaccination: evaluation of efficacy atdifferent degrees of maturation and of migration capacityR. Ridolfi (Forlì - Italy)

17.45 Autologous T cells expressing the tumor antigenMAGE-3 to treat melanoma patientsV. Russo (Milan - Italy)

Rapporteur: L. Ridolfi (Forlì - Italy)

Room LAGUNA

15.00 - 16.00New Drug Approach in MelanomaChair: G. Fasola (Udine - Italy), V. Chiarion Sileni (Padua - Italy)

15.00 Palonosetron: a second-generation5-HT3 receptor antagonist E. Bajetta (Milan - Italy)

15.30 Fotemustine and metastatic melanomaP. Queirolo (Genoa - Italy)

16.00 - 17.00Melanoma in Pregnancy and ChildhoodChair: S. Alberico (Trieste - Italy), G. Borroni (Pavia - Italy)

16.00 Melanoma in pregnancyS. Alberico (Trieste - Italy)

16.30 Melanoma in childhoodG. Borroni (Pavia - Italy)

Rapporteur: G. Borroni (Pavia - Italy)

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17.00 - 18.30Report SessionChair: P. A. Ascierto (Naples - Italy)

17.00 Report on Dermatology and Telediagnosis G. Trevisan (Trieste - Italy)

17.30 Report on Basic Research and New Technologies G. Stanta (Trieste - Italy)

18.00 Report on Surgery M. Foletto (Padua - Italy)

Saturday, November 5, 2005Room GRADO

8.30 - 11.00

Report Session

Chair: A. Testori (Milan - Italy)

8.30 Report on Follow-up and Adjuvant TreatmentA. Paccagnella (Venice - Italy)

9.00 Report on HistopathologyM. Pippione (Turin - Italy)

9.20 Report on Melanoma in Pregnancy and ChildhoodG. Borroni (Pavia - Italy)

9.40 Report on Immunology L. Ridolfi (Forlì - Italy)

10.10 Report on Advanced Melanoma A. Freschi (Aviano - Italy)

10.40 Report on Gruppo di Lavoro Infermieri e Data Managers

Room AQUILEIA

9.00 - 9.45

Psychooncology

Chair: E. Capovilla (Padua - Italy)

9.00 Psychological aspects in patients with melanomaM. A. Annunziata (Aviano - Italy)

9.30 Assessing the impact of breaking bad news to melanomapatients: the project for a pilot survey in four Italian centers P. Sedona (Venice - Italy)

9.45 - 10.30

Medico-Legal Issues

Chair: G. Mustacchi (Trieste - Italy)

Melanoma: medico-legal issues

G. Del Ben (Aviano - Italy)

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Room LAGUNA

10.30 - 11.00

Free Communications / Poster Discussion

Chair: P. A. Ascierto (Naples - Italy), G. Trevisan (Trieste - Italy)

Plenary Session

Room GRADO

11.00 - 12.30

Journal Club: Update 2005

Chair: R. Ridolfi (Forlì - Italy), P. A. Ascierto (Naples - Italy), C. R. Rossi (Padua -Italy)

Epidemiology

E. Bidoli (Aviano - Italy)

Basical research

G. Bianchi Scarrà (Genoa - Italy)

Dermatology

R. Bono (Rome - Italy)

Surgery

C. R. Rossi, M. Foletto (Padua - Italy)

Medical Oncology

P. Marchetti (Rome - Italy)

12.30

Closing remarks

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“INFERMIERE E MELANOMA:PROBLEMI APERTI”Grado, 4-5 novembre 2005

Venerdì, 4 novembre 2005Grand Hotel Astoria - Sala Lido - Largo S. Grisogono, 3, Grado

14.30 -18.30

Gruppo di lavoro Infermieri e Data Managers

Relatori: D. Chizzolini, A. M. Colussi, L. Mazzega Sbovata,R. Paroni, N. Pressello

14.30 La gestione infermieristica degliaccessi venosi centrali

15.30 La lettera di dimissione infermieristica

16.30 L’assistenza al paziente sottoposto atrattamento radio-chemioterapico

17.30 Ruolo dell’Infermiere di Ricerca

18.30 Discussione e conclusioni

Sabato, 5 novembre 2005Palazzo dei Congressi - Via Dante, Grado

Sala LagunaRelatori: A. Spada, G. Tabaro, D. Kilmartin, M. Andreuccetti

8.30 - 9.00 Ricerca clinica in oncologia

9.00 - 9.30 Aspetti critici e organizzazionedi una struttura sanitaria

9.30 - 10.00 Ruolo del Data Manager: esempio diorganizzazione di una rete di ricerca

10.00 - 10.20 Discussione e conclusioni

Sala Grado10.40 - 11.00 Report del Gruppo di Lavoro Infermieri

e Data Managers

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S. Alberico (Trieste - Italy)

M. Andreuccetti (Pisa - Italy)

M. A. Annunziata (Aviano - Italy)

P. A. Ascierto (Naples - Italy)

E. Bajetta (Milano - Italy)

M. G. Bernengo (Turin - Italy)

F. Bertolini (Milan - Italy)

G. Bianchi-Scarrà (Genoa - Italy)

E. Bidoli (Aviano - Italy)

R. Bono (Rome - Italy)

P. Boggio (Novara - Italy)

G. Borroni (Pavia - Italy)

G. Botti (Naples - Italy)

P. Calzavara-Pinton (Brescia - Italy)

E. Capovilla (Padua - Italy)

C. Caracò (Naples - Italy)

P. Carli (Florence - Italy)

C. Castell i (Milan - Italy)

V. Chiarion Sileni (Padua - Italy)

D. Chizzolini (Aviano - Italy)

A. M. Colussi (Aviano - Italy)

G. Comella (Naples - Italy)

M. D’Incalci (Milan - Italy)

F. De Cian (Genoa - Italy)

V. De Pangher Manzini (Gorizia - Italy)

G. L. De Salvo (Padua - Italy)

G. Del Ben (Aviano - Italy)

F. Di Fil ippo (Rome - Italy)

R. Dummer (Zurich - Switzerland)

A. Eggermont (Rotterdam - The Netherlands)

G. Fasola (Udine - Italy)

M. Foletto (Padua - Italy)

E. Fraccalanza (Udine - Italy)

A. Freschi (Aviano - Italy)

A. Gatti (Trieste - Italy)

O. Geatti (Udine - Italy)

B. Giannotti (Florence - Italy)

N. Glumac (Ljubljana - Slovenia)

M. Guida (Bari - Italy)

V. Hegyi (Bratislava - Slovak Republic)

H. Kerl (Graz - Austria)

D. Kilmartin (Padua - Italy)

J. Kirkwood (Pittsburgh - USA)

L. Lanfrancone (Milan - Italy)

G. Lazzaro (Milan - Italy)

J. Lipozen@iæ (Zabgreb - Croatia)

G. Macripò (Turin - Italy)

M. Maio (Siena - Italy)

A.M. Manganoni (Brescia - Italy)

P. Marchetti (Rome - Italy)

G. Mazzarol (Milan - Italy)

L. Mazzega Sbovata (Aviano - Italy)

S. Minucci (Milan - Italy)

L. M. Mir (Villejuif - France)

G. Moise (Gorizia - Italy)

M. C. Montesco (Padua - Italy)

N. Mozzil lo (Naples - Italy)

G. Mustacchi (Trieste - Italy)

A. Paccagnella (Venice - Italy)

G. Palmieri (Sassari - Italy)

R. Paroni (Aviano - Italy)

P. Patrone (Udine - Italy)

M. Pippione (Turin - Italy)

M. A. Pizzichetta (Aviano - Italy)

N. Pressello (Trieste - Italy)

M. P. Protti (Milan - Italy)

P. Queirolo (Genoa - Italy)

M. Rescigno (Milan - Italy)

A. Riccobon (Forlì - Italy)

L. Ridolfi (Forlì - Italy)

R. Ridolfi (Forlì - Italy)

A. Romanini (Pisa - Italy)

M. Roseano (Trieste - Italy)

C. R. Rossi (Padua - Italy)

V. Russo (Milan - Italy)

M. Schiavon (Udine - Italy)

P. Sedona (Venice - Italy)

H. P. Soyer (Graz - Austria)

A. Spada (Aviano - Italy)

I. Stanganelli (Ravenna - Italy)

G. Stanta (Trieste - Italy)

G. Tabaro (Aviano - Italy)

A. Testori (Milan - Italy)

G. Tosti (Milan - Italy)

G. Trevisan (Trieste - Italy)

G. M. Verdecchia (Forlì - Italy)

A. Veronesi (Aviano - Italy)

W. Wallnöfer (Bolzano - Italy)

I. H. Wolf (Graz - Austria)

P. F. Zampieri (Merano - Italy)

FACULTY

Venue

Congress Centre

Via Dante, Grado (GO, Italy)

All details on how to reach Grado are available on the web sitewww.theoffice.it/IMI05

Official Languages

Italian and English. No simultaneous interpretation will be provided.

CME CREDITS

Event n° 11516 - 214742 (Oncology, Dermatology and Venereology,Surgery) 8 credits

Event n° 11516 - 214950 (Nurses) 5 credits

To obtain the credits, you must attend the whole event,

fill in the questionnaires and the evaluation form.

REGISTRATION AND ACCOMMODATION

Registration Fee (VAT Included)

IMI Members € 96,00

IMI Non Members € 144,00

Nurses Free

For registration, hotel accommodation and other details, please visit theweb site www.theoffice.it/IMI05 and use the relevant form, available onthe same web site. The registration fee includes attendance, Meetingkit, certificate of attendance, abstract volume, open coffee, lunch andwelcome cocktail.

Organising Secretariat

The officeVia San Nicolò 1434121 Trieste (TS)ph. 0039 040 368343 int. 15fax 0039 040 368808melanoma@theoffice.itwww.theoffice.it/IMI05

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GENERAL INFORMATION

IGEA - Technology for Clinical Biophysics

Italfarmaco

Schering Plough

Boehringer Ingelheim

Chiron

G.O.C.N.E. - GruppoOncologico Cooperativo del Nord-Est

IDI Farmaceutici

Mavi Sud

Fastbrain

Medtronic Italia

Roche

Teleflex Medical