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Pierre G. Carlier
Imagingрактическая конфереваний"
Institute of Myology, CHU Pitié-Salpêtrière, Paris, France, CEA, IBFJ, MIRCen, Fontenay-aux-Roses, France,
Imaginggroupobjectivesрактическая конфереваний"
• ToassistHCPswithdiagnosticimaging
Imaginggroupobjectivesрактическая конфереваний"
• ToassistHCPswithdiagnosticimaging
• TopromotebetterNMDimagingprotocols
Imaginggroupobjectivesрактическая конфереваний"
• ToassistHCPswithdiagnosticimaging
• TopromotebetterNMDimagingprotocols Educationgroup
Imaginggroupobjectivesрактическая конфереваний"
• ToassistHCPswithdiagnosticimaging
• TopromotebetterNMDimagingprotocols
• TohelpdevelopingmoreadvancedNMDimagingprotocols
Educationgroup
Imaginggroupobjectivesрактическая конфереваний"
• ToassistHCPswithdiagnosticimaging
• TopromotebetterNMDimagingprotocols
• TohelpdevelopingmoreadvancedNMDimagingprotocols
Educationgroup
Researchgroup
Routineexam1
T1wimaging
Ø Whole-body
Ø QualitativeØ IdentificationofdiseasespecificpatternsofmuscleinvolvementØ Diagnosis
RSMD1-SEPN1BethlemMUllrichCMDLGMD2AEmery-Dreyfuss MD2-LMNA
MuscularDystrophieswithRigidityoftheSpine
Mercurietal.,Ann.Neurol.,2010
SkeletalmuscleNMRimaginginneuromusculardisorders
7/12
2
Fat/waterseparationtechniques(Dixon)
Ø Oftenspatiallylimited
Ø QuantitativeØ PreciseassessmentoffattydegenerativechangesØ Monitordiseaseprogressioninnaturalhistory/therapeutictrials
Quantitativefatimagingwasabletomeasurediseaseprogressionina cohort of limb-girdle musculardystrophy 2I (LGMD2I) patientsovera12-monthperiod
Willisetal.,PLoSONE,2013
SkeletalmuscleNMRimaginginneuromusculardisorders
Routineexam
8/12
Imaginggroup:diagnosticactivitiesрактическая конфереваний"
• Musclediseases:fattyinfiltrationpatterns
• Peripheralnervediseases:fastlygrowingbutnotestablishedyet
• Motorneuron,NMjunction,mitochondrialdiseases: littleornorole
Imaginggroup:diagnosticactivitiesрактическая конфереваний"
• R.Y.Carlier(USQV)G.Tasca(URoma):muscleMRI
• O.Scheidegger(UBern):MRneurography
• P.G.Carlier(IoM):qMRIandOMs
HCP’simagingcontactperson
CPMS
Imaginggroup:diagnosticactivitiesрактическая конфереваний"
• R.Y.Carlier(USQV)G.Tasca(URoma):muscleMRI
• O.Scheidegger(UBern):MRneurography
• P.G.Carlier(IoM):qMRIandOMs
HCP’simagingcontactperson
CPMS
Imaginggroup:diagnosticactivitiesрактическая конфереваний"
• R.Y.Carlier(USQV)G.Tasca(URoma):muscleMRI
• O.Scheidegger(UBern):MRneurography
• P.G.Carlier(IoM):qMRIandOMs
HCP’simagingcontactperson
CPMS
Imaginggroup:educationalactivitiesрактическая конфереваний"
• SOPs
Imaginggroup:educationalactivitiesрактическая конфереваний"
• SOPs
Imaginggroup:educationalactivitiesрактическая конфереваний"• SOPs
Imaginggroup:educationalactivitiesрактическая конфереваний"
• SOPs
– Updateonmuscleimaging–Dec17
– MRneurography–O.Scheidegger–Apr18
Imaginggroup:educationalactivitiesрактическая конфереваний"
• SOPs
• MuscleMRIatlasofpathologies:integrationof
Imaginggroup:educationalactivitiesрактическая конфереваний"
• SOPs
• MuscleMRIatlasofpathologies
• Hands-ontrainingandworkshop
ü June25th-June27th,2018:Paris,InstituteofMyology,immediatelyaftertheMyologySummerSchool
UpdateondiagnosticimagingHands-onsessionondiagnosticandquantitativeMRimagingHands-onsessiononmusclestrengthandactivitymeasurements
Imaginggroup:researchactivitiesрактическая конфереваний"
• Introducefasterimagingprotocols
• Encourageshiftfromqualitativetoquantitativeprotocols
• Developinter-siterobustnormalizationprocedures
Imaginggroupрактическая конфереваний"
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