（専門科目 / Major Subjects...平成30年度医科学専攻シラバス MEDICAL SCIENCE SYLLABUS 2018 （専門科目 / Major Subjects）平成30年4月 / April2018 神戸大学医学部学務課

平成 30 年度医科学専攻シラバス

MEDICAL SCIENCE SYLLABUS 2018

（専門科目 / Major Subjects）

平成３０年４月 / April２０１８

神戸大学医学部学務課

Student Affairs Section

Graduate School of Medicine Kobe University

共通科目のシラバスについては、

授業案内ページに決定分から随時アップします。

General Sublects ↓ here

http://www.med.kobe-u.ac.jp/GRADN/DRC/drc-schedule.htm

専門科目－Major Subjects－

生理学・細胞生物学講座　Physiology and Cell Biology

膜動態学　Membrane Dynamics 1

細胞生理学　Cell Physiology 2

システム生理学　System Neuroscience 3

神経情報伝達学　Neuronal Signaling 4

生体構造解剖学　Structural Medicine and Anatomy 5

神経分化・再生　Neural Differentiation and Regeneration 6

分子脳科学　Molecular Brain Science 7

血管生物学　Vascular Biology 8

発生・再生医学　Developmental Biology and Regenerative Medicine 9

生化学・分子生物学講座　Biochemistry and Molecular Biology

生化学　Biochemistry 10

分子細胞生物学　Molecular and Cellular Biology 11

膜生物学　Membrane Biology 12

シグナル統合学　Molecular and Cellular Signaling 13

病態シグナル学　Pathogenetic Signaling 14

薬理学　Pharmacology 15

病理学講座　Pathology

病理学　Pathology 16

病理診断学　Diagnostic Pathology 17

病理ネットワーク学　Pathology Network 18

病理病態学　Molecular Medicine & Medical Genetics 19

微生物感染症学講座　Microbiology and Infectious Diseases

臨床ウイルス学　Clinical Virology 20

ワクチン学　Vaccinology 21

感染制御学　Infectious Disease Control 22

感染病理学　Infectious Disease Pathology 23

感染治療学　Infectious Diseases Therapeutics 24

感染・免疫学（ウイルス感染）　Infection and Immunology(Virus Infection) 25

地域社会医学・健康科学講座　Social/Community Medicine and Health Science

地域医療支援学　Community Medicine and Career Development 26

橋渡し科学　Translational Science 27

医薬食品評価科学　Food and Drug Evaluation Science 28

疫学　Epidemiology 29

法医学　Legal Medicine 30

内科学講座　Internal Medicine

循環器内科学　Cardiovascular Medicine 31

不整脈先端治療学　Arrhythmia 32

消化器内科学　Gastroenterology 33

呼吸器内科学　Respiratory Medicine 34

糖尿病・内分泌内科学　Diabetes and Endocrinology 35

総合内科学　General Internal Medicine 36

腎臓内科学　Nephrology 37

免疫内科学　Rheumatology & Clinical Immunology 38

神経内科学　Neurology 39

腫瘍・血液内科学　Oncology/Hematology 40

血液内科学　Hematology 41

内科系講座　Internal Related

放射線診断学　Diagnostic and Interventional Radiology 42

機能・画像診断学　Functional and Diagnostic Imaging Research 43

分子イメージング学　Molecular Imaging 44

放射線腫瘍学　Radiation Oncology 45

小児科学　Pediatrics 46

こども急性疾患学　General Pediatrics 47

こども総合療育学　Developmental Pediatrics 48

皮膚科学　Dermatology 49

精神医学　Phychiatry 50

臨床検査医学　Laboratory Medicine 51

病因病態解析学　Metabolomics Research 52

先端緩和医療学　Palliative Medicine 53

薬剤学　Pharmaceutics 54

小児先端医療学　Advanced Pediatric Medicine 55

外科学講座　Surgery

食道胃腸外科学　Gastrointestinal Surgery 56

肝胆膵外科学　Hepato-Biliary-Pancreatic Surgery 57

乳腺内分泌外科学　Breast and Endocrine Surgery 58

心臓血管外科学　Cardiovascular Surgery 59

呼吸器外科学　Thoracic Surgery 60

小児外科学　Pediatric Surgery 61

外科系講座　Surgery Related

整形外科学　Orthopaedics 62

リハビリテーション機能回復学　Rehabilitation Medicine 63

脳神経外科学　Neurosurgery 64

眼科学　Ophthalmology 65

耳鼻咽喉科頭頸部外科学　Otolaryngology-Head and Neck Surgery 66

腎泌尿器科学　Urology 67

産科婦人科学　Obstetrics and Gynecology 68

形成外科学　Plastic Surgery 69

麻酔科学　Anesthesiology Surgery 70

口腔外科学　Oral and Maxillofacial Surgery 71

Division

Field of Study

Instructors

Major Subject

Title Special Lecture Ⅰ ６ credits Semester 1st

Evaluation

Evaluation Criteria

Information Regarding Preparationand Related Classes

Title Special Lecture Ⅱ ４ credits Semester 1st,2nd

Evaluation

Evaluation Criteria


Title Seminar ３ credits Semester 2nd

Evaluation

Evaluation Criteria


Written Test　　　・　　　Oral Test　　　・　　　Research Report


Research report and attendance


Details will be announced in class.



Theme and ObjectivesWe teach reserch paper reading activity and understanding endoplasmic reticulum functions.Our current lectures are as follows:

(1) Molecular mechanisms underlying the tubular and sheet structures of endoplasmicreticulum(2) Machinery for the translocon-independent insertion of membrane protein into endoplasmicreticulum(3) Reconstitution of organelles using artificial membrane


Medical Science Syllabus 2018

Toshiaki Sakisaka

Theme and ObjectivesWe teach new knowledge, experimental techniques, and paper writing concerning endoplasmicreticulum functions. Our current lectures are as follows:

(1) Molecular mechanisms underlying the tubular and sheet structures of endoplasmicreticulum(2) Machinery for the translocon-independent insertion of membrane protein into endoplasmicreticulum(3) Reconstitution of organelles using artificial membrane

We teach fundamental knowledge and experimental techniques concerning membrane trafficand its molecular mechanism. Our current lectures are as follows:

(1) Molecular mechanism of vesicle budding(2) Molecular mechanism of vesicle targeting(3) Molecular mechanism of vesicle docking and fusion

Physiology and Cell Biology

Membrane Dynamics


Membrane Dynamics

Theme and Objectives

Division

Field of Study

Instructors

Major Subject

Title Special Lecture Ⅰ ６ credits Semester 1st, 2nd

Evaluation

Evaluation Criteria


Title Special Lecture Ⅱ ４ credits Semester 1st, 2nd

Evaluation

Evaluation Criteria



Evaluation

Evaluation Criteria



Y. Minami, M. Nishita, M. Endo, M. Hayashi

Theme and ObjectivesCell polarity signaling plays important roles in regulating cellular differentiation andinmaintaining stemness of tissue stem cells (or cancer stem cells) and/or progenitor cells.Theaim of Special Lecture II is to learn advanced knowledge of molecular and cell biology withaparticular emphasis on the roles of cell polarity signaling in cellular differentiationandmaintenace of stemness, and to acquire advanced technique to perform well-designedexperiments to unveil important and difficult biological questions. Through SpecialLecture II, itis of importance to learn how to write a scientific paper.

Cell polarity and migration are regulated elaborately during developmental morphogenesis,andtheir aberrant regulation is associated with cancers and various inflammations. The aimofSpecial Lecture I is to learn basic knowledge of cell biology, in particular the regulation ofcellpolarity and migration under physiological and/or developmental conditions, and toacquireprinciple molecular and cell biological technique to examine cell polarity and migrationunderphysiological and pathological conditions. We will also present basic knowledge andtechnique tounderstand and monitor gene regulation under physiological and pathologicalconditions.


Cell Physiology


Cell Physiology (regulation of cell polarity and migration)




The percentage of attendance and the result of oral test.In somecases, research report will be required.





Theme and ObjectivesIn addition to Special Lectures I & II, through Seminar it is of importance to developone'sscientific ability to present his or her own findings clearly and logically and todiscussimportant biological issues with other scientists. One can also learn how to readandunderstand scientific papers reported by others through Seminar and can develop furtherone'sability to write his or her own papers with high quality.


Division

Field of Study

Instructors

Major Subject

Title Special Lecture Ⅰ ６ credits Semester

Evaluation

Evaluation Criteria


Title Special Lecture Ⅱ ４ credits Semester

Evaluation

Evaluation Criteria


Title Seminar ３ credits Semester

Evaluation

Evaluation Criteria




Level of achievement in the subject described above





Theme and ObjectivesStudents will present their own experimental results and learn how to develop discussions.They need to discuss following points: the originality of their research, whether logicalexplanation for their result ethics for the research (sample size and feasibility of their data),what additional experiments need to be performed, and their next question in the field. Theyneed to start to develop their own field to be more independent. In addition, students willintroduce a qualified research paper.



Hiroaki WAKE, Yoshihisa TACHIBANA, Shota SUGIO, AkikoMIYAMOTO

Theme and ObjectivesIn this lecture series, we develop the special lectureⅠof physiological functions of neuronalcircuits to their abnormalities. We use the psychiatric or neurological disorder model mice toanalyze their abnormalities in neuronal and glial funcions, thereby contributing to reveal theneuronal and glial mechanism for disease formation.

Our research has focused on understanding the neuronal basis for higher brain functions,thereby contributing to reveal the mechanism for psychitaric and neurological disorders. Inthis lecture, we combine two photon in vivo imaging with viral infection to visualize theneuronal and glial construction and functions. Our aim is to to get the technique for in vivoimaging and mathematically analyze the images to summarize the functions of neuronalcircuits.


System Neuroscience


Neuroscience, Neurophysiology


Division

Field of Study

Instructors

Major Subject


Evaluation

Evaluation Criteria



Evaluation

Evaluation Criteria


Title Seminar ３ credits Semester 1st

Evaluation

Evaluation Criteria



Evaluation will be done by attendance and knowledge.

Theme and ObjectivesThe participants read recent papers related to neuronal signaling, report their results of theexperiments, and acquire more knowledge and methodologies in neuronal signaling in addition tothose nurturing the ability of English presentation and writing.


Written Test　　　・　　Oral Test　　　・　　　Research Report

Written Test　　　・　　Oral Test　　　・　　　Research Report


Written Test　　　・　Oral Test　　　・　　　Research Report



Naoaki Saito, Takehiko Ueyama, Naoko Adachi

Theme and ObjectivesThis lecture aims to help participants understand the characteristic signaling pathways usinganimal models and study their involvement in neuronal diseases. The participants take specialsubjects to acquire a wide range of systematic and interdisciplinary knowledge andmethodologies in neuronal signaling in addition to those nurturing the ability of English writing.

This lecture aims to help participants understand basic mechanisms of intracellular signalingnetwork and characteristic signaling pathways in neuron. The basic techniques for molecularbiology and cell biology are also lectured.


Neuronal Signaling


Neuronal Signaling


Division

Field of Study

Instructors

Major Subject


Evaluation

Evaluation Criteria



Evaluation

Evaluation Criteria



Evaluation

Evaluation Criteria



Structural Medicine and Anatomy



Individuals displaying sufficient knowledge in essential embryologyand neuroanatomy will pass this course.

Individuals who can read recent research papers and explaincontents through presentation will pass this course.



Structural Medicine and Anatomy

Ryo Nitta,Satoshi Kikkawa


During this course, we teach the participants the theory and practice of (1) methods to labelneural circuit, (2) methods available for birth ate of neurons, (3) methods to identify geneexpression and expression of their transcripts, morphologically. Participants are expected tounderstand functional meanings of genes through the experiments utilizing mutant mice. Wealso teach the methods how to analyze data and to write research papers.

At the end of this course, the participants are expected to understand (1) functions of genesexpressing during the early embryogenesis, (2) development of neural tube and neural crestfrom which CNS and PNS are developed, respectively, (3) differentiation of neural tube intoprimary and secondary brain vesicles and region-specific gene expression, (4) generation ofcerebral cortex from telencephalon and genes related to corticogenesis, and (5) molecularmechanisms underlying formation of neural circuits.

The journal club is designed for the participants to understand the recent progress andtechnical terms in this field. The participants are expected to learn how to read and writeresearch papers in English through the presentation.



Individuals displaying sufficient knowledge in essential embryologyand neuroanatomy will pass this course.




Division

Field of Study

Instructors

Major Subject


Evaluation

Evaluation Criteria


Title Special Lecture Ⅱ ４ credits Semester 2nd

Evaluation

Evaluation Criteria



Evaluation

Evaluation Criteria



Hideki Enomoto

Theme and ObjectivesJournal club will be held with the research papers of development, regeneration anddevelopmental disorders of the nervous system.

A series of lectures will focus on the basic knowledge about development, regeneration andpathology of the nervous system toward deeper understanding of the principle and applicationof molecular biology techniques and mouse genetic approaches to tackle the problems in thefield.

Neural Differentiation and Regeneration

Development, Pathology and Regeneration of the NervousSystem


Development, Pathology and Regeneration of the NervousSystem




Based on the degree of understanding found in the researchreport





Theme and ObjectivesPractial lesson will be held to learn neuroanatomy, molecular biology, cell biology, biochemistryand mouse genetic approaches.


Division

Field of Study

Instructors

Major Subject


Evaluation

Evaluation Criteria



Evaluation

Evaluation Criteria



Evaluation

Evaluation Criteria



Kazuhiro Kobayashi, Motoi Kanagawa, Wataru Satake

Theme and ObjectivesBy integrating various research methods including genome analysis, proteomics, cell biology,glycobiology, genetic engineering, and others, students will be given opportunities to participateactively in researches that aim to elucidate pathogenesis of muscular dystrophy andParkinson’s disease, to understand the function of related disease causing genes, to developnovel intervention aiming for personalized medicine, and to identify genetic factors thatdetermine memory and intelligence. Through these studies, students will learn the skills toassemble various experimental methods, interpret data, and summarize data for publication.

The advance of genome science has brought a change in experimental methodology to “systematic andcomprehensive”, through which the entire nucleotide sequence of human genome has been recentlydetermined and the genetic code is now being systematically deciphered (functional analysis). Also it isknown that majority of diseases and biological processes we encounter in our daily lives such aslifestyle-related diseases, higher brain function like memory and intelligence, and others, are affected bygenetic factors, highlighting the immeasurable impacts of genome science on medical and life sciences.The lecture will expose students to current trends, significance, and development in medical applicationof genome technology, systematic genetic polymorphism analysis, systematic gene expression analysis,mouse mutation analysis, proteomic analysis, and other genome science methodologies in current brainresearch field.


Molecular Brain Science


Molecular Brain Science


Research Report

To master basic research methods

Research Report



To master how to make presentation

Theme and ObjectivesStudents will be given opportunities to master the skills to understand the contents and thesignificance of cutting-edge papers on medical and life sciences, summarize important pointsof the papers and make presentation of the papers. Students will learn the skills to presenttheir study in Special Lecture II.

To perform experiments aiming to fulfill research objectives andto present the results of the study

Research Report

Division

Field of Study

Instructors

Major Subject


Evaluation

Evaluation Criteria



Evaluation

Evaluation Criteria



Evaluation

Evaluation Criteria



Ability to read and understand papers in vascular biology and tomake appropriate presentations

Theme and ObjectivesThe vascular system is comprised of hierarchical network and plays a crucial role in tissuehomeostasis by circulating the blood throughtout the body. To gain deep knowledge about thedevelopment of endothelial cells and vascular morphogenesis in vertebrates, tips to read andunderstand representative papers in vascular biology will be instructed.

Acquisition of advanced knowledge and techniques in vascularbiology, and skills of manuscript preparetion



Acquisition of basic knowledge and techniques in vascular biology




Masanori Hirashima

Theme and ObjectivesThe vascular system is comprised of hierarchical network and plays a crucial role in tissuehomeostasis by circulating the blood throughtout the body. To investigate the development ofendothelial cells and vascular morphogenesis in vertebrates at the molecular and cellular levels,advanced knowledge and research methods will be instructed through experiments ofendothelial labelling, gene expression analysis, and so on in transgenic mice of vascularmorphogenesis-related genes. Based on up-to-date insights and research methods, how tomake research plan will be instructed. How to write up scientific papers will also be instructed.

The vascular system is comprised of hierarchical network and plays a crucial role in tissuehomeostasis by circulating the blood throughtout the body. Basic knowledge and researchmethods will be instructed about the development of endothelial cells, vascular morphogenesis,and structure of hieralhycal vascular network in vertebrates.


Vascular Biology


Vascular Biology


Division

Field of Study

Instructors

Major Subject

Title Special Lecture Ⅰ ６ credits Semester 1st,2nd

Evaluation

Evaluation Criteria



Evaluation

Evaluation Criteria


Title Seminar ３ credits Semester 1st,2nd

Evaluation

Evaluation Criteria





Degree of understaning found in the research report

Theme and ObjectivesPractical lesson wiill be held in basic molecular biology techniques to understand theirprinciples.




Takashi Tsuji

Theme and ObjectivesJournal club will be held with the research papers of preimplantation development, stem cellbiology, genome biology and epigenetics.

A series of lectures will focus on the basic techniques of molecular biology to understandingdevelopmental biology and regenerative medicine, particularly in relation to preimplantationdevelopment, stem cell biology, genome biology and epigenetics.


Developmental Biology and Regenerative Medicine


Developmental Biology and Regenerative Medicine




Division

Field of Study

Instructors

Major Subject


Evaluation

Evaluation Criteria



Evaluation

Evaluation Criteria



Evaluation

Evaluation Criteria




Evaluate collectively both by attedance and by research reports.




Evaluate collectively by both the attedance and research reports.

Theme and ObjectivesSeminar is intended to obtain up-to-date knowledge on signal transduction research throughjournal club routinely held in Biochemistry division. Students are encouraged to make theirprogress reports in English so as to get discussion ability useful in the international scientificconferences, meetings, etc.

Evaluate collectively by both the attedance and research reports.


Shun-ichi Nakamura

Theme and ObjectivesBased on knowledge and skills acquired in Special Lecture I, this course is programmed tomaster fundamental requirements, i.e ., making hypotheses, prove them through experimentalprocesses and study each step necessary for the publication in the international journals.

Human bodies comprise almost 50 trillion cells, which are highly differentiated and formtissues and organ with a fine tune of collaborate networks which enables a variety of eventsincluding motor function, digestion, immunity and memory formation. Disruption of suchnetworks, i.e., gain or loss of function of key molecules in the regulation, may cause a varietyof disorders in motor, metabolism, immunological and brain functions. This course is intendedfor students to become familiar with from basic to up-to-date knowledge on signaltransduction and to master fundamental skills necessary for cell signaling researches.

Biochemistry and Molecular Biology

Biochemistry


Biochemistry


Division

Field of Study

Instructors

Major Subject

Title Special Lecture Ⅰ ６ credits Semester 1st and 2nd

Evaluation

Evaluation Criteria


Title Special Lecture Ⅱ ４ credits Semester 1st and 2nd

Evaluation

Evaluation Criteria


Title Seminar ３ credits Semester 1st and 2nd

Evaluation

Evaluation Criteria







Based on contents and an attitude of the presentation, andaccuracy of their reply to scientific questions at the lab meetings.

Theme and ObjectivesStudents are instructed to read research papers and learn reading skills, way to set up properexperimental plans, and methods to evaluate research results, for a deeper understanding ofthe roles of oncogenes and tumor suppressor genes in cancers and developmentalabnormalities. In addition, students are required to present contents of the research articleson a regular basis at the lab meetings to improve oral presentation skills.

Based on the contents of research reports.


Akira Suzuki

Theme and ObjectivesIn this class, students learn methods to analyze and evaluate the roles of oncogenes andtumor suppressor genes in the onset and progression of cancers, but also in the onset ofvarious other diseases and abnormalities in development and differentiation. For this purpose,students need to expand knowledge and research techniques mastered in the Special LectureI, and to learn up-to-date experimental procedures in molecular biology, cellular biology, andembryonic engineering. We aim to publish the research results as research articles.

Most oncogenes and tumor suppressor genes are involved not only in the onset andprogression of cancers, but also in the onset of various other diseases and abnormalities indevelopment and differentiation. In this class, students learn basic concepts and experimentalmethods that are required to understand the roles of oncogenes and tumor suppressor genesin cancers and developmental abnormalities, especially focusing on p53 and PTEN signalingpathway which are frequently mutated in cancers, and Hippo signaling pathway which is gainingincreasing attention.


Molecular and Cellular Biology


Molecular and Cellular Biology


Division

Field of Study

Instructors

Major Subject


Evaluation

Evaluation Criteria



Evaluation

Evaluation Criteria



Evaluation

Evaluation Criteria



Toshiki Itoh, Hideyuki Mukai, Kazuya Tsujita

Theme and ObjectivesThe state-of-art techniques will be introduced for the visualization of morphological changes in biologicalmembranes in cells; including optical systems for the visualization of intracellular trafficking that utilizevarious fluorescent protein tags or fluorescent chemicals. Students will be also trained for techniquesthat enable recapitulation of morphological changes in biological membrane in vitro, by using fluorescent,differential interference and electron microcopies. Further, biochemical methods for the quantification ofmolecular interactions between proteins and lipids will be introduced. In the course, the students willmaster the above methodologies of membrane biology, as well as coordinate their own research projectsin the field; including membrane morphogenesis, cell migration, and intracellular membrane traffic. Theprojects will be aimed for publications of their own research papers.

To restrain free diffusion of soluble molecules is necessary for establishment and maintenanceof biological system. Cells that constitute our body achieve such a limitation by separatingtheir inner space from outer environment by biological membranes. Thus, the regulatorymechanisms of membrane dynamism are important for a variety of physiological eventsincluding cell growth, differentiation, immune response, and neurotransmission. In this course,the students will study the basic principles in the field of membrane biology, as well as betrained for tissue culture and genetic transformation techniques.


Membrane Biology


Membrane Biology



Evaluations will be made according to the degree ofaccomplishment in the above subjects.





Theme and ObjectivesThe biological membrane is one of the most fundamental cellular constituents involved in variousphysiological events such as intracellular vesicular trafficking, cell division and cell migration. The keyfeature of the membrane is the significant physical flexibility that supports its dynamic morphologicalchanges. Involved in this process is a group of cytosolic proteins that reversibly interact with lipidbilayer, creating unique curvature thus shape of the membrane. Recent research by many laboratorieshas revealed necessary roles of such proteins in endocytosis, thus is gathering increasing attentionsfrom the scientific community. In this course, students will be trained to understand and follow up thescientific topics not only in this particular research field, but also cell biology in general. Through theintensive discussions, it is aimed that the students will become able to find a creative solution forpossible obstacles in their own research projects.



Division

Field of Study

Instructors

Major Subject

Title Special ResearchⅠ ６ credits Semester 1st,2nd

Evaluation

Evaluation Criteria


Title Special Research II ４ credits Semester 1st,2nd

Evaluation

Evaluation Criteria



Evaluation

Evaluation Criteria



Evaluation will be based on reports.




Takashi Matozaki, Yoji Murata, Yasuyuki Sito, Takenori Kotani

Theme and ObjectivesAims of this training course will further develop the knowledge and experimental techniquesacquired by students in “Special Research I”, and make the students understandfundamentals of, and the latest progress in signaling mechanisms of bioactive substances,such as hormones, growth factors and differentiation factors. Students can learn the basicknowledge and the latest progress of this research area using progressive research papers asteaching materials. Furthermore, based on the basic knowledge, instructors give studentsspecific guidance on how to plan actual experiments, to process or evaluate experimentaldata, and to work up the results into a scientific paper.

A variety of bioactive substances acts on cells in vivo to evoke diverse array of intra- andinter-cellular signaling pathways, and thereby regulates various biological responses. In thistraining course, each student carries out research experiments to understand fundamentalsof, and the latest progress in signaling mechanisms of bioactive substances, such ashormones, growth factors and differentiation factors. Under the guidance of instructors, eachstudent carries out biochemical, molecular biology, and cell biology experiments, which requirespecial techniques and knowledge.


Molecular and Cellular Signaling





Evaluation will be based on presentation with a question andanswer session in this seminer.

Theme and ObjectivesIn this seminar, to understand fundamentals of signaling mechanisms of bioactive substances,such as hormones, growth factors or differentiation factors, students read the latest scientificpapers regarding this research area under the guidance of instructors. Through this process,students specifically learn how to set up hypotheses, to plan actual experiments and to carryout the experiments. Furthermore, based on the basic knowledge, students are trained for aresearcher who can make plans for actual research experiments and report findings of theresearch in oral presentations.

Evaluation will be based on reports.


Division

Field of Study

Instructors

Major Subject


Evaluation

Evaluation Criteria



Evaluation

Evaluation Criteria



Evaluation

Evaluation Criteria




Based on contents of the research reports.


Instructions are given during the classes.


Based on contents and an attitude of the presentation, andaccuracy of their reply to the scientific questions at laboratorymeetings.

Theme and ObjectivesStudents are instructed to read research papers in the field of cell adhesion molecules tolearn reading skills, way to set up proper experimental plans, and methods to evaluateresearch results for deeper understanding of the molecular mechanism by which cell adhesionmolecules regulate cell movement, proliferation, adhesion, and polarization. In addition,students are required to present contents of the research articles on a regular basis at ajournal club to improve oral presentation skills.

Based on contents of the research reports.


Yoshimi Takai

Theme and ObjectivesIn this class, students learn methods to analyze and evaluate roles and modes of action of celladhesion molecules in cellular functions, such as cell movement, proliferation, adhesion, andpolarization. For this purpose, students need to learn state-of-art experimental procedures inbiochemistry, molecular biology, and cell biology, by expanding knowledge and researchtechniques taught in the Special LectureⅠ. We aim to publish the research results asresearch articles.

Cellular signaling pathways and their crosstalk, which are associated with cell movement,proliferation, adhesion, and polarization, strictly regulate ontogeny and organogenesis.Dysregulation of the signaling pathways results in a variety of pathological conditions, such astransformation, invasion and metastasis of cancer cells, as well as neuropsychiatric disorders,and atherosclerosis. In this class, students learn basic concepts and experimental methods tounderstand the roles of cell adhesion molecules in regulation of cell movement, proliferation,adhesion, and polarization.




Pathogenetic Signaling


Division

Field of Study

Instructors

Major Subject


Evaluation

Evaluation Criteria



Evaluation

Evaluation Criteria



Evaluation

Evaluation Criteria



Theme and ObjectivesStudents will present their own experimental results and learn how to develop discussions. Thefollowing points will be discussed: Whether the aim of research is appropriately determined,whether the results are obtained in an unbiased manner with proper controls and sufficient samplesizes, whether experimental results are logically interpreted, what additional experiments need tobe performed, whether the results are unique and conceptually advanced, what is the nextquestion in the field. In addition, students will introduce a qualified research paper related toneuropsychopharmacology. Students are encouraged to learn background literature and to providethe history of a pertinent research field as well as its future perspective.

Based on attendance at the lectures and the outcome of oralexaminations. Research reports are occasionally requested.


Based on the quality of oral presentations and oral examinations.




Tomoyuki FURUYASHIKI, Shiho KITAOKA, Hirotaka Nagai

Theme and ObjectivesIn this lecture series, students will learn how genetic susceptibilities and environmental factorsalter functions of neural molecules, thereby affecting cognitive and emotional behaviors andprecipitating psychiatric disorders. Students will also learn how to use preclinical models,especially acute and chronic stress models in rodents, and how to analyze associated molecular,cellular and neural circuit changes. Validity and limitations of these models will also be discussed.Learned as well as newly developed methods will be employed to identify novel molecular, cellularand neural-circuit mechanisms underlying cognitive and emotional behaviors as well as thesedysfunctions. Given their own results, students will learn how to assemble experimental resultsand write an original paper.

Neuropsychopharmacology aims to understand actions of psychotropic drugs and functions ofneural molecules as their targets, thereby contributing to pharmaceutical development forpsychiatric disorders. In this lecture series, students will learn roles and functions of neuralmolecules underlying cognitive and emotional behaviors, such as neurotransmitters, growth factorsand inflammation-related molecules, in relation to structures and functions of neural circuits andneuron-glia interactions. Students will also learn methods of analyses of neural functions atmolecular, cellular, neural circuit and behavioral levels with spatiotemporally specific manipulationof gene expression and neuronal activity.


Pharmacology


Neuropsychopharmacology



Based on attendance at the lectures and the outcome of oralexaminations. Research reports are occasionally requested.

Division

Field of Study

Instructors

Major Subject


Evaluation

Evaluation Criteria

Information Regarding Preparation andRelated Classes


Evaluation

Evaluation CriteriaInformation Regarding Preparation andRelated Classes


Evaluation

Evaluation Criteria


Title Practice ２ credits Semester 1sr, 2nd

Evaluation

Evaluation Criteria


Pathology

Theme and Objectives1) Students will be able to classify and describe the pathologic changes of organs, tissues and cellsaccording to (1) regressive changes, (2) progressive changes, (3) metabolic disturbances, (4) circulatorydisturbances, (5) inflammation, (6) neoplasia and (7) malformation and discuss their etiology andpathogenesis.2) Students will be able to explain the morphologic and functional characteristics of various pathologicstatus in each organ.3) Students will be able to analyze the pathobiology of whole organs in diseased individual.



Pathology

Pathology

YOKOZAKI, Hiroshi; KOMA, Yu-ichiro; SHIGEOKA, Manabu, NISHIO, Mari


Theme and Objectives1) Students will understand the principles of common procedures of molecular pathology.2) Students will be able to select the appropriate techniques of molecular pathology (immunofluorescence,immunohistochemistry, histochemistry, in situ hybridization, Western blotting, Northern blotting, Southernblotting, polymerase chain reaction) for the analysis of specimens from patients.3) Students will be able to overview the recombinant DNA experiments necessary for the molecularpathological analysis.

Evaluate the levels of achievements of above educational objectives according tothe 5-level grading system of Kobe University (S, A, B, C and F) . Grades S, A, Band C are the passing marks.


Theme and Objectives1) Students will be able to describe the morphological changes of diseased individuals, tissues and cellswith appropriate pathological diagnosis.2) Students will master the conventional histopathological methods.3) Students will master the molecular pathological methods (immunofluorescence, immunohistochemistry,histochemistry, in situ hybridization, Western blotting, Northern blotting, Southern blotting, polymerasechain reaction) for the analysis of diseased specimens.




Evaluate levels of the ability for the diagnosis of surgical, biopsy and autopsymaterials.

Theme and Objectives1) Students will be able to perform autopsy according to the established method of Rokitansky or Virchow,then constract proper macroscopic as well as histopathological diagnoses.2) Students will be able to handle surgical and biopsy materials, describe the morphological alterationsaccording to the concept of general pathology then place the accurate histopathological diagnoses.3) By conducting the practices described in 1) and 2), students will be able to reach the level ofpathological diagnosis to pass the board examination by the Japanese Society of Pathology.

Evaluate the levels of achievements of above educational objectives according tothe 5-level grading system of Kobe University (S, A, B, C and F) . Grades S, A, Band C are the passing marks.



Division

Field of Study

Instructors

Major Subject


Evaluation

Evaluation Criteria



Evaluation

Evaluation Criteria



Evaluation

Evaluation Criteria


Title Practice ２ credits Semester 2nd

Evaluation

Evaluation Criteria




Diagnostic Pathology, immunohistochemistry

Theme and ObjectivesDiagnostic pathology is one of the most important fields in medicine. To recognize the basic ofthe morphology of the diseases is essential for the various researches. In our department,there is a number of experts of various organs and special diseases. Various studies are ongoing with combination of morphology, immunohistochemsitry, and the other special studies.

　Oral Test　　

　Oral Test　　　


The results will be graded by the degree of the achievement ofthe preset aims.

Theme and ObjectivesDiagnostic pathology is one of the most important fields in medicine. To recognize the basic ofthe morphology of the diseases is essential for the various researches. In this lecture, we willlecture about the grossing practice, diagnostic practice using advanced microscopic system,and the skills about immunohistochemistry.



Theme and ObjectivesDiagnostic pathology is one of the most important fields in medicine. To recognize the basic ofthe morphology of the diseases is essential for the various researches. In this seminar, welecture about the basics of the pathology, and aim for the improvement of your skills on thereading and recognition of the medical articles and textbook, and the communication.


Pathology

Diagnostic Pathology

Tomoo Itoh, Yasuhiro Sakai, Shigeo Hara, Fumi Kawakami,Takashi Yamasaki, Keiichiro Uehara


Theme and ObjectivesDiagnostic pathology is one of the most important fields in medicine. To recognize the basic ofthe morphology of the diseases is essential for the various researches. Based on the variousstudies regarding morphology, immunohistochemistry, and the other things, the researcherswill describe articles on the top-ranking journals.




Division

Field of Study

Instructors

Major Subject


Evaluation



Evaluation



Evaluation



Evaluation


Diagnostic Pathology

Theme and ObjectivesMajor histopathological findings, immunohistochemical characteristics, and molecular featuresof both neoplastic and non-neoplastic disorders in selected organs will be leant.



Pathology

Section of Pathology Network

Yoh Zen, Yukiko Morinaga

Evaluated according to estimated achievement


Theme and ObjectivesTo make a research plan and to learn basic methodology for future pathological studies onselected organs.



Theme and ObjectivesTo study pathological features, molecular aspects, and clinicopathological correlation throughliterature search for a couple of difficult cases allocated. Students will also be asked to makea presentation of the cases.





Theme and ObjectivesTo learn gross examination of pathology specimens, staining methods of tissue slides,immunohistochemistry through practical training. Telepathology (network-based remotepathological diagnosis) will also be experienced.




Division

Field of Study

Instructors

Major Subject


Evaluation

Evaluation Criteria


Title Special Lecture Ⅱ ４ credits Semester 1st

Evaluation

Evaluation Criteria



Evaluation

Evaluation Criteria



Professor Yoshitake Hayashi

Theme and ObjectivesDivision of Molecular Medicine & Medical Genetics, Department of Pathology is an emergingdiscipline within pathology, and focuses in the study and diagnosis of disease through theexamination of molecules within organs, tissues or bodily fluids. Our class shares someaspects of practice with both anatomic pathology and clinical pathology, molecular biology,biochemistry, proteomics and genetics, and is sometimes considered a "crossover" discipline.It is multi-disciplinary in normal and pathological tissues, and focuses mainly on thesubmicroscopic aspects of disease and unknown illnesses with strange and unrecognizedcauses. In this class, you can learn how to prepare data and how to complete for publicationf

Pathology is a the most important field that is concerned with the diagnosis of various diseasebased on the gross, microscopic, chemical, immunologic and molecular examination of organs,tissues, and whole bodies. Division of Molecular Medicine & Medical Genetics includes themolecular pathology and diagnostic pathology. The distinction between molecular anddiagnostic pathology is increasingly vague by the introduction of technologies that require newexpertise and the need to provide patients and referring physicians with integrated diagnosticreports. In this class, you can learn what is the pathology and its importance in both practicaland research fields.

Pathology

Molecular Medicine & Medical Genetics


Molecular Medicine & Medical Genetics




evaluation of ability to understand how to treat with normal andpathological tissues




evaluation of ability to make an experimental design andunderstand and make scientific papers

Theme and ObjectivesIn this class, you can learn how to proceed with your research through the presentation ofyour own work and other students' work, and you can understand how to find something newand important in your own work through discussion with other students and professors. Youcan learn recent important discovery by reading high-profiled scientific journals with theinstruction of professors. By this class, you can learn how to present your own work andcommunicate with otehrs in English. And you can understand Molecular Medicine, MedicalGenetics and Pathology by completing your own project as a scientific paper.

evaluation of ability to understand of genetical approaches withnormal and pathological tissues

Division

Field of Study

Instructors

Major Subject


Evaluation

Evaluation Criteria



Evaluation

Evaluation Criteria



Evaluation

Evaluation Criteria




to acquire the knowledge and technique of Virology, Cellularbiology, Molecular biology and Immunology




to acquire how to present the knowledge and technique

Theme and ObjectivesLecture for acquisition of the knowledge and technique of Virology, Cellular biology, Molecularbiology and Immunology Lecture for the way to presenting the knowledge and technique ofVirology, Cellular biology, Molecular biology and Immunology

to acquire how to write the report


Yasuko Mori

Theme and ObjectivesLecture for acquisition of the knowledge and technique of Virology, Cellular biology, Molecularbiology and Immunology Lecture for the way to wrting report about Virology, Cellular biology,Molecular biology and Immunology

Lecture for acquisition of the knowledge and technique of Virology, Cellular biology, Molecularbiology and Immunology

Microbiology and Infectious Diseases

Clinical Virology


Clinical Virology


Division

Field of Study

Instructors

Major Subject


Evaluation

Evaluation Criteria



Evaluation

Evaluation Criteria



Evaluation

Evaluation Criteria


Written Test　　　・　　　Oral Test　　　・　　　○Research Report

Status of the students to learn basic technologies

Written Test　　　・　　　Oral Test　　　・　　○Research Report



Masanori Kameoka

Theme and ObjectivesBased on the basic knowledge and technology obtained through "Special Lecture Ⅰ",students will learn (1) further advanced strategies for vaccine construction, (2) methods forevaluating their efficacy and (3) technologies including analytical methods required for theirdevelopment from various aspects. Students will construct a new strategic candidate vaccineand learn the process of vaccine develpment. Further, students will obtain abilities to compiletheir data into papers by their presentation and publishment.

Students will learn (1) medical and social significance of vaccination and (2) methods fordeveloping new strategic vaccines and evaluating their efficacy. Students will (1) constract acandidate vaccine by manipulating genes of pathogens using recombinant technology, (2)analyze expression products by the gene in vitro and (3) learn basic knowledge and technologyfor evaluating vaccine-induced immune responses in experimental animals.


Vaccinology


Vaccine Development



Status of the students to obtain abilities to read academic papersand to present these papers

Theme and ObjectivesStudents will obtain abilities to read academic papers relating to "Special Lecture Ⅰ" and"Special Lecture Ⅱ" and to present these papers in a well understandable fashion.

Status of the students to learn applied technologies and theability to construct paper

Written Test　　　・　　　Oral Test　　　・　　　○Research Report

Division

Field of Study

Instructors

Major Subject


Evaluation

Evaluation Criteria



Evaluation

Evaluation Criteria



Evaluation

Evaluation Criteria



Ikuo Shoji

Theme and ObjectivesBased upon the basic knowledge and techniques acquired from the Special Research I,students will systematically learn the microbial pathogenesis and current concepts indiagnostics, therapeutics and prevention. The Special Research II will allow students toacquire knowledge and experimental techniques at molecular, cellular and animal levels, whichwill be necessary for the development of new diagnostic, therapeutic and preventivemeasures. This course willteach students to make, test, and modify working hypotheses based upon the experimentaldata. Students will learn how to write a scientific paper and should be able to publish their

k

This course is designed for students who want to acquire basic knowledge of microbialgenome structures, gene expression mechanisms, and microbial protein structures andfunctions. Students will learn experimental techniques for analysis of the host-microbeinteractions and the mechanisms of virus proliferation.


Infectious Disease Control


Infectious Disease Control




Acquisition status of basic knowledge and basic experimentalskills




Acquisition status of scientific reading comprehension andpresentation skills

Theme and ObjectivesLearning activities include reading papers related to the Special Research I and II, andpresentation skill training necessary for scientific research.

Acquisition status of advanced knowledge, advancedexperimental skills, and scientific writing skills.

Division

Field of Study

Instructors

Major Subject


Evaluation

Evaluation Criteria



Evaluation

Evaluation Criteria



Evaluation

Evaluation Criteria



Professor Yoshitake Hayashi

Theme and ObjectivesThe mission of this class on infectious disease pathology is to acquire, advance, anddisseminate knowledge in the fields of infectious diseases that will help identify, control andprevent human and animal disease and/or contribute to public health. You can learn infectiousdiseases through the discussion with other students and professors. In this class, you canlearn how to prepare data and how to complete your paper with recent important findings. Andby this class, you can understand our mission to control the infectious diseases which is atrue threat to our society. In this class, you can learn how to prepare data present your ownwork and how to complete for publication of your paper.

Our research focus is on viral infected hepatitis and hepatology. Main project is to establishthe international network against the global spreading of emerging and reemerging infectiousdiseases, in Systematic and Politico-Economical as well as Medical and Scientic Researchaspects. As an education for PhD students, lectures on Molecular and Genetic analysis ofinfectious diseases, particularly epidemiologic study and genotype analysis of Hepatitis B virus,Dengue Virus, HIV (various patient groups in various geographical areas) and the problems ofDrug resistant bacteria are being carried out. Diagnostic and clinicopathological studies of liverdiseases are also being researched. In this class, you can learn how to research on infectiousdiseases


Infectious Disease Pathology


Infectious Disease Pathology




We evaluate the ability to understand how to treat with normaland infectious tissues




We evaluate the ability to present the research results andcommunicate and exchange various scientific informations.

Theme and ObjectivesIn this class, you can learn how to research work of infectious diseases through thepresentation of your own work and other students' work, and you can understand how to findsomething new and important in your own work through discussion with other students andprofessors. You can learn recent important discovery by reading high-profiled scientificjournals with the instruction of professors. By this class, you can learn how to present yourown work and communiate with others in English. And you can understand overviews ofvarious infectious diseases by completing your own work as a scientific paper.

We evaluate the ability to understand of genetic and molecularapproaches on infectious materials and to make scientic papers.

Division

Field of Study

Instructors

Major Subject


Evaluation

Evaluation Criteria



Evaluation

Evaluation Criteria


Title Seminar ３ credits Semester 1st, 2nd

Evaluation

Evaluation Criteria


Title Practice ２ credits Semester 1st, 2nd

Evaluation

Evaluation Criteria



Overall knowledge and understanding on clinical infectiousdiseases.

Theme and ObjectivesLearning how to manage infections and fever of unknown origin.

We evaluate the ability to evaluate patients' condition, reasonabletherapeutic decision making, and understanding of patientevaluation.

○Written Test　　　・　　　Oral Test　　　・　　　Research Report




Written Test　　　・　　　Oral Test　　　・　○Research Report

Written Test　　　・　○Oral Test　　　・　　　Research Report

Studies on therapeutics: Antimicrobials, non-antimicrobials, evaluation of therapy outcomes.

We evaluate the quality of studies on diagnostics.

Theme and Objectives Clinical reasoning, patients evaluation, choice of treatment, treatment evaluation.


We evaluate the quality of studies on diagnostics.

Written Test　　　・　　　Oral Test　　　・　　○Research Report

Infectious Diseases Therapeutics

Theme and Objectives Studies on diagnostics: epistemology, symptomatology, interpretation of test results,evaluation of safety and cost effectiveness about examinations, Evidence Based Medicine(EBM), production of severity scores and their validation. Also one may participate indevelopment of novel or modified tests such as automated Gram staining machine.



Infectious Diseases Therapeutics

Kentaro Iwata, Goh Ohji

Division

Field of Study

Instructors

Major Subject


Evaluation

Evaluation Criteria



Evaluation

Evaluation Criteria



Evaluation

Evaluation Criteria




Acquisition of basic knowledge and basic experimental skills




Acquision of ability to reading and presentation skills

Theme and ObjectivesThis class aims to obtain the abilities to read academic journals regarding microbiology andimmunology and persuasively present their contents.

Acquisition of advanced knowledge and experimental skills, andscientific writing skills


Jun Kunisawa

Theme and ObjectivesThis class aims to extend knowledge and experimental skills for the advanced and cutting-edge studies in the field of microbiology and immunology. Also, students are expected topublish their own data in the academin international journals.

This class aims to obtain basic knowledge and experimental skills about microbiology andimmunology.


Virus Infection


Infectious Immunology


Division

Field of Study

Instructors

Major Subject


Evaluation



Evaluation



Evaluation



Evaluation



Evaluation Criteria includes the daily activities and an oral test.

Theme and ObjectivesIn this course, students are expected to learn and participate in the daily practice in the fieldof Community Medicine. Based on the knowledge acquired in the above courses, students areexpected to become highly skilled person in their field.

The degree of achievement about a report of research



Submission of manuscript


Theme and ObjectivesBased on the knowledge of Special Lecture I, the graduate students perform medical researchprojects that are associated with community medicine and write scientific papers.



Theme and ObjectivesRead and understand important papers, and share these papers with the lab members. Also,develop communication skills through presentation of data and clinical assessment.



Community Medicine and Career Development

Theme and Objectives1. Gain basic knowledge of community medicine, general medicine, healthcare for the elderly,education and lifelong support for students, medical trainees, and healthcare providers.2. Learn basic methodology necessary for analyses of Clinical research concerning qualityimprovement of community medical care, general medical care, healthcare for the elderly,education and lifelong support for students, medcial trainees, and healthcare providers.



Social/Community Medicine and Health Science

Community Medicine and Career Development

Tsuneaki Kenzaka, Ryo Nishio

Division

Field of Study

Instructors

Major Subject


Evaluation

Evaluation Criteria



Evaluation

Evaluation Criteria



Evaluation

Evaluation Criteria




Based on attendance at the lectures and the outcome of oralexaminations. Research reports are requested by necessity.




Based on attendance at the lectures and the outcome of oralexaminations.

Theme and ObjectivesStudents will present their own study results on special lecture I, and learn how to developdiscussion. The following points will be discussed: whether the research question isappropriately determined, whether the study data are obtained in righteous processes andadequately managed, whether the interpretation is properly supported by the results, whetheradditional analyses are required, whether the results are unique and contribute to theimprovement of public welfare, and what is the next question. In addition, students will carefullyevaluate a qualified research paper related to the field, and are encouraged to reviewbackground literature and to understand the history of clinical and translational researchevolution as well as its future perspectives.

Based on attendance at the lectures and the outcome of oralexaminations. Research reports are requested by necessity.


Yoji NAGAI

Theme and ObjectivesPreclinical studies and clinical trials are the key components in medical technologydevelopments, whereby proactive initiatives of academic expertise are strongly expected. Atthe same time, the current medical technologies should be continuously evaluated andoptimized, through well designed implementation studies, with the risk for public healthadequately controlled. The success is dependent not only on basic science and cutting edgemedicine, but also on multidisciplinary science, including clinical science, regulatory science anddata science. Also, execution of clinical trials is justified only through strict adherence to theglobally authorized research ethics. Thus, this special lecture aims to understand scientific andethical principles required for the implementation of clinical trials.

“Translational Science” is the field of investigation focused on understanding the scientific andoperational principles underlying each step of the translational process. Translation is theprocess of turning observations in the laboratory, clinic and community into interventions thatcan improve the health of individuals and public. Thus, it includes not only the processes toapply basic research findings to humans, but also the processes to execute clinical trials, toextend the results in clinical practice, and to transfer clinical study findings to the populationhealth. Each process must be implemented through ethically, legally and socially righteousmethodologies, which are realized, for instance, by animal experiments, clinical trials andobservational studies. This special lecture aims to cultivate scientific principles underpinningsuch translational processes, and to learn how to facilitate respective processes leading to theimprovement of medicine and public welfare.


Translational Science


Translational Science, Clinical Science


Division

Field of Study

Instructors

Major Subject


Evaluation

Evaluation Criteria



Evaluation

Evaluation Criteria



Evaluation

Evaluation Criteria



Norihiro SAKAMOTO

Theme and ObjectivesAdvanced information analysis techniques are essential for constructing scientific evidencesregarding effects and side effects of supplements and functional foods.The objectives of this lecture are to learn information gathering techniques such asbibliographic retrieval, data mining for analizing large quantities of data, and meta-analysis forbuilding scientice evidences.

Supplements and functional foods are very popular with people becoming health-conscious.However effects and side effects of some of such foods and drugs are not wellanalyzed and known.The objectives of this lecture are to know frequently used supplements and functional foodsand to understand their functional mechanism, effects, and side effects.


Food and Drug Evaluation Science


Food and Drug Evaluation Science


Oral Test

Adequate understanding of effects and side effects of frequentlyused supplements and fuctional foods

Oral Test



Adequate understanding of bibliographic retrieval, data mining,and meta-analysis

Theme and ObjectivesIn this seminar, acquisition of documents regarding effects or side effects of a typicalsupplement or functional food, meta-analysis on them, and construction of scientificevidences are conducted.

Adequate understanding of bibliographic retrieval, data mining,and meta-analysis

Research Report

Division

Field of Study

Instructors

Major Subject


Evaluation

Evaluation Criteria



Evaluation

Evaluation Criteria



Evaluation

Evaluation Criteria



Masakazu Shinohara, MD, PhD　　Emma Niba, PhD

Theme and ObjectivesTheme: GeneticsObjectives: To write a short paper on the molecular analysis of the genetic disorders. (Shinohara, Niba)Theme: Analytical ChemistryObjectives: To write a report on the analytical chemistry based molecular epidemiology. (Shinohara)

Theme: GeneticsObjectives: (1) To understand the advanced research on the genes associated with the development of genetic disorders. (Shinohara, Niba) (2) To understand the outlines of analytical methods of the gene mutations and their effects. (Shinohara, Niba)Theme: Analytical ChemistryObjectives: (1) To understand basic principal of analytical chemistry based molecular epidemiology. (Shinohara)

Social/Community Medicine and Healthcare Science

Epidemiology


Genetics, Analytical Chemistry




The research reports will be graded on the basis of their content,organization, and quality of writing (or oral presentation).Attendance and class participation will be figured in the finalgrading.




Presentation and participation in the discussion will be figured inthe final grading.

Theme and ObjectivesTheme: GeneticsObjectives: To present your own ides on how the defective molecular machineries of spinal muscular atrophy lead to the loss of the motor neuron. (Shinohara, Niba )Theme: Analytical chemistryObjectives: To present your report on the analytical chemistry based molecular epidemiology. (Shinohara )

Division

Field of Study

Instructors

Major Subject


Evaluation

Evaluation Criteria

Information RegardingPreparation and Related Classes


Evaluation

Evaluation Criteria



Evaluation

Evaluation Criteria


Theme and Objectives To learn the basis of the Legal Medicine, and to improve your skills on the reading of themedical articles and textbooks of forensic medicine.

Oral Test

Evaluated according to estimated achievement.


Theme and Objectives To make a research plan and to learn basic methodolgy for advanced and practicable studieson forensic pathology and forensic toxicology.

Oral Test



Theme and Objectives The fundamental knowledge and skills of forensic pathology and forensic toxicology will belearnt.

Oral Test




Legal Medicine

Legal Medicine

Ueno Yasuhiro, Kondo Takeshi, Takahashi Motonori

Legal Medicine

Division

Field of Study

Instructors

Major Subject


Evaluation

Evaluation Criteria



Evaluation

Evaluation Criteria



Evaluation



Evaluation

Evaluation Criteria



One have to master the basic and clinical skill to examine,diagnose, and treat cardiovascular diseases.

Theme and Objectives Objectives are to take part in the team medical treatment and to master the clinicalknowledge and ability in cardiovascular diseases. Another objectives to develop newdiagnostics and therapies associated with cardiovascular diseases.

One can present one's data and discuss them.



One can refer some medical papers and write a research paperin English by oneself.


Theme and ObjectivesBased on the knowledge of Special Lecture I, the graduate students perform medical researchprojects that are associated with cardiovascular diseases and write scientific papers.

One can write a research paper in English and give scientificconsideration to medical problems.


Theme and ObjectivesTo master the scientific thinking about the pathogenesis of cardiovascular diseases.



Cardiovascular Medicine

Theme and ObjectivesTo learn the pathophysiology, diagnosis, and novel therapies of cardiovascular diseases,especially ischemic heart disease, heart failure, and arrythmia. Recent progresses in therapiesof cardiovascular diseases were remarkable and graduate students should catch up with them.Another aim of this program is to acquire the ability to present one's research results, tocomunicate and discuss in English, and to write a research and clinical papers.



Internal Medicine


Kei-ichi Hirata, Tatsuro Ishida, Tomoya Yamashita, HidekazuTanaka, Hiromasa Ohtake, Tetsuya Harai, Shumpei Mori, Hiroyuki

Division

Field of Study

Instructors

Major Subject


Evaluation

Evaluation Criteria



Evaluation

Evaluation Criteria



Evaluation



Evaluation

Evaluation Criteria



One have to master the basic and clinical skill to examine,diagnose, and treat cardiovascular diseases.

Theme and Objectives Objectives are to take part in the team medical treatment and to master the clinicalknowledge and ability in cardiovascular diseases. Another objectives to develop newdiagnostics and therapies associated with cardiovascular diseases.

One can present one's data and discuss them.



One can refer some medical papers and write a research paperin English by oneself.


Theme and ObjectivesBased on the knowledge of Special Lecture I, the graduate students perform medical researchprojects that are associated with cardiovascular diseases and write scientific papers.

One can write a research paper in English and give scientificconsideration to medical problems.


Theme and ObjectivesTo master the scientific thinking about the pathogenesis of cardiovascular diseases.




Theme and ObjectivesTo learn the pathophysiology, diagnosis, and novel therapies of cardiovascular diseases,especially arrythmia. Recent progresses in therapies of cardiovascular diseases wereremarkable and graduate students should catch up with them. Another aim of this program isto acquire the ability to present one's research results, to comunicate and discuss in English,and to write a research and clinical papers.



Internal Medicine

Cardiovascular Medicine/Arrythmia

Ken-ichi Hirata, Koji Fukuzawa, Kunihiko Kiuchi, KensukeMatsumoto, , Seimi Satomi-Kobayashi, Mitsuru Takami, Yu

Division

Field of Study

Instructors

Major Subject


Evaluation



Evaluation



Evaluation


Title Practice ２ credits Semester 1st,2nd

Evaluation




Theme and ObjectivesTo obtain medical skills and develop advanced medicine in the field of gastroenterology.






Theme and ObjectivesTo solve pathophysiologic mechanisums of infectious disease,inflammatory disease,andcancers in the field of gastroenterology.To develop advanced medicine in the field of gastroenterology.



Theme and ObjectivesStudents will introduce scientifically important papers and present their own research results.



Gastroenterology

Theme and ObjectivesTo understand pathophysiologic mechanisms,diagnosis,and treatments of infectiousdiseases,inflammatory diseases,and cancers in the field of gastroenterology.



Internal Medicine

Gastroenterology

Masaru Yoshida,Yoshihiro Yano,Namiko Hoshi,AtsuhiroMasuda,Hideyuki Shiomi,Yoshinori Morita,Tsukasa Ishida

Division

Field of Study

Instructors

Major Subject


Evaluation

Evaluation Criteria



Evaluation

Evaluation Criteria



Evaluation

Evaluation Criteria



Evaluation

Evaluation Criteria


Division of Respiratory Medicine deals with respiratory diseases, including bronchila asthma,COPD, sleep apnea, infectious diseases, cancers and interstitial pneumonia. Main objective inthe graduate course is to study pathophysiology of respiratory disease; Diagnosis andtreatment; New imaging technology; New biochemical assays; and New medication.




Internal Medicine

Respiratory Medicine

Yoshihiro Nishimura, MD, PhD

Respiratory Medicine


Introduction to Paper Writing

The students will present research results in our research meetngs and the both domesticand international academic conferences to improve the presentation skills.





Clinical Skill

Theme and ObjectivesFollowings have been extensively carried out in our division:1) Development of new technology and therapy against resoiratory diseases2) Chemo- and/or radiotherapy against thoracic malignancies3) Pariative care in patients with malignant diseases4) Sleep study using polysomonograph in patients with sleep apnea, cardiac diseases, andmetabolic diseases.

Research Presentation


Paper Writing



Division of Respiratory Medicine focuses on pathophysiology of respiratory diseases and thedevelopment of new technology: Molecular biology and molecular genetic approaches; Geneticdiagnosis. The students will read a lot of research papers and prepare for writing papers.


Division

Field of Study

Faculty

Major Subject


Evaluation

Evaluation Criteria


Evaluation

Evaluation Criteria


Evaluation

Evaluation Criteria


Evaluation

Evaluation Criteria

Diabetes and Endocrinology

Theme and Objectives1. Gain basic knowledge of the pathogenesis and pathophysiology of diabetes and endocrinediseases. 2. Learn basic methodology necessary for analyses of the pathogenesis andpathophysiology of diabetes and endocrine diseases.



Internal Medicine

Diabetes and Endocrinology

Wataru Ogawa, Yutaka Takahashi, Genzo Iguchi, Tetsuya Hosooka, Yushi Hirota,Shun-ichiro Asahara, Hidenori Fukuoka, Yuko Okada

Submission of manuscript in English


Theme and Objectives1. Learn up-dated findings of pathogenesis and pathophysiology clarified by state-of-artmethodology. 2. Learn how to translate basic finding to clinical setting. 3. Perform researchbased on the leading-edge knowledge and technology, analyze the data produced, and write apaper.

Evaluated by the knowledge and skills learned.


List problems based on clinical examination, their assessment,and make clinical plans to solve the problems.

Theme and ObjectivesReceive training to become specialists in diabetes and/or endocrine diseases in clinicalpractice as follows: 1. Learn about various clinical tests to assess pathophysiological states ofdiabetes and endocrine diseases. 2. Perform clinical test on actual cases and assess theresults, and draw the problems. 3. Make clinical plans to solve the problems.

Understanding of papers and presentation


Theme and Objectives1. Read and understand important papers on diabetes and endocrinology, and share thesepapers with the lab members. 2. Develop communication skills through presentation of dataand clinical assessment.

Division

Field of Study

Instructors

Major Subject


Evaluation

Evaluation Criteria



Evaluation

Evaluation Criteria



Evaluation

Evaluation Criteria



Evaluation

Evaluation Criteria



You search the manuscripts concerned with lifestyle-related illness and vesseral function, andassess the validity and its adaptation. You also present the summary of each manuscripts.


submission of manuscript



Internal Medicine

General Medicine

Kenji Kanazawa

General Medicine


understanding of CONSORT statement and interpritation of thevalidity of selected manuscripts

Theme and ObjectivesYou understand the CONSORT statement. You pick up the medical problems of out/inpatients and search the manuscripts related with them. You teach the information about themto medical students and make the students understand the validity and adaptation in clinicalsituation.

evaluation of understanding about clinical validity, medicalmorality and adaptation




You will research the interventional trial of lifestyle-realated illness evaluated by above threemethods and establish the manuscript about the relationship of the result and clinicalparameter of lifestyle-related illness.

confirmation of basal technical skill of above three methods


You have to understand the cause and clinical significance of large vessel disease andarteriosclerosis in the lifestyle-related illness and learn about the meaning of following method,1) carotid intima-media thickness measured by ultrasonography, 2) endothelial functionmeasured by flow-mediated dilation, 3) degree of arteriosclerosis measured by pulse wavevelocity.




Division

Field of Study

Instructors

Major Subject


Evaluation



Evaluation



Evaluation



Evaluation


Nephrology

Theme and ObjectivesOur goal is to perform basic and clinical studies concerning the resolution ofpathophysiologicalmechanism and development of treatment in nephrolgy field. Our main subjects are resolutionof pathophysiological mechanism regarding bone-mineral disorders, cardio-renal syndromeassociated with chronic kidney disease, glomerulonephritis and rejection in kidneytransplantation. It is important to understand the basic knowledge on above themes and learnthe essential techniques using animal models and human materials.



Internal Medicine

Nephrology Division of Nephrology and Clinical Immunology

Shinichi Nishi, Hideki , Shunske Goto, Keiji Kono, Mikiko Yoshikawa, KentaroWatanabe

Achievement states of related skils


Theme and ObjectivesThrough the basic and clinical learning, you have to learn the method of data analysis on yourown research and how to describe scientific articles.

Achievement states on research meeting and conference, article


Theme and ObjectivesYou have to learn basic knowledge to be able to understand the contents concerning ownresearch theme published in articles and presentation on academic conferences.




Achievement states of qualification

Theme and ObjectivesYou strive to get qualification of certifying physician and specialist physician on nephrologyfield and related fields. For examples, you must to try the qualification of certifying physicianinSocieties of Nephrology, Dialysis treatment, Kidney transplantation and Hypertension.

Achievement states of related skils



Division

Field of Study

Instructors

Major Subject


Evaluation



Evaluation

Evaluation Criteria



Evaluation



Evaluation




Theme and ObjectivesIn this course, students are expected to learn and participate in the daily practice in the fieldof Rheumatology. Based on the knowledge acquired in the above courses, students areexpected to become highly skilled person in their field.




Evaluation Criteria includes an original paper and/or oralpresentation at a scientific meeting.


Theme and ObjectivesThe objectives of this course is to learn advanced knowledge and techniques in the field ofRHeumatology and clinical immunology. Also how to write a scientfiv paper will be lectured.The goal of the course is to present the data in a scientific meeting and to write an originalpaper.



Theme and ObjectivesThe objectives of this course is to learn how to present your own data in an oral and posterpresentation. Also how to communicate with other people in a meeting wiil be learned.



Rheumatology / Clinical Immunology

Theme and ObjectivesThe objectives of this course is to learn basic knowledge and techniques in the field ofRheumatology and clinical immunology. The course includes how to read scientific articles,how to design experiments, and how to interpretate the experimental results.



Internal Medicine

Rheumatology & Clinical Immunology

A. Morinobu, Y. Kogata, G. Kageyama, A. Ohnishi

Division

Field of Study

Instructors

Major Subject


Evaluation

Evaluation Criteria



Evaluation

Evaluation Criteria



Evaluation

Evaluation Criteria


Title Practice 2 credits Semester 1st, 2nd

Evaluation

Evaluation Criteria


Theme and ObjectivesTo study clinical neurology and to improve skills for diagnosis and treatment, the participantswill be expected to take part in seeing patients in neurology ward and outpatient clinics. Theparticipants are supposed to become a board-certificated neurologist.

Research ReportEvaluated by degree of advancement including being board-certificated

l i tDetails will be announced in class.

Research Report

Research Report

Evaluated by degree of advancement

Research Report




Theme and ObjectivesThe participants will be studying current methods of diagnosis for neurological disorders, suchas neuroimaging and genetic diagnosis, through lectures and reading articles of milestone inneurology. The participants will be also required to improve skills of presentation anddiscussion based on these issues.



Kenji Sekiguchi, Takehiro Ueda, Norio Chihara, Yoshihisa Ohtsuka, Hisatsugu Tachibana

Theme and ObjectivesThe participants will be receiving lectures on neurodegenerative diseases, neuroimmunology,cerebrovascular diseases and other neurological problems by designated guest lecturers andare supposed to understand pathomechanisms of neurological disorders. The participants alsowill be expected to discuss possibilities of disease modifying therapy on these diseases.

To conduct productive and originative studies, there are many processes to be consideredincluding setting a designated goal, information gathering by reported articles, making andcarrying out a definite plan, evaluating your results and writing a report. The participants willbe mastering all these steps and will be supposed to submit at least one original article to amajor journal.

Internal Medicine

Neurology


Neurology


Division

Field of Study

Instructors

Major Subject


Evaluation

Evaluation Criteria



Evaluation

Evaluation Criteria



Evaluation

Evaluation Criteria



Evaluation

Evaluation Criteria


Theme and ObjectivesThe primary goal is to gain insight into the clinical principles and practice of medical oncologyand hematology based on curricula developed by the Japanese Society of Medical Oncologyand the Japanese Society of Hematology. Students should understand the rationale forengaging drug therapy against cancers in multiple organ systems and learn basic oncology,including molecular biology. Students should also obtain basic knowledge and methodology forclinical research and acquire skills of translational research necessary to solve clinicalquestions by basic research.




Internal Medicine

Medical Oncology/Hematology

Hironobu Minami

Medical Oncology/Hematology

Achieve competence level



Objectives are to learn methods for clinical research in medical oncology and hematologybased on knowledge of clinical pharmacology and advanced anticancer drug therapy, to performpharmacological research using knowledge of molecular target drugs and their mechanism ofaction and resistance, and to obtain the ability to investigate leukemogenesis and newapproaches for stem cell transplantation. Final goal is to publish results from these basic andclinical research.

Theme and ObjectivesGoals are to obtain skills for critical reading of publications, to achieve competency to evaluatethe strength of evidence, and to develop skills necessary to incorporate evidence-basedmedicine into oncology practice. Students should improve their capability for accurate andeffective presentation at case conferences and research conferences.






Theme and ObjectivesLearn how to diagnose and treat various cancers in multiple organ sytems includinghematological malignancies. Gain experience with a sufficient number of cases necessary tosuccessfully take certification examinations for medical oncologists and/or hematologistsauthorized by the Japanese Society of Medical Oncology or the Japanese Society ofHematology, respectively. Obtain skills to manage toxicities of stem cell tranplantation. Learnmanagement of oncology patients including supportive therapy, palliative care, andcommunicaton skills to deliver bad news. Students should function as active members of theoncology team and assume a prominent role in the multidisciplinary treatment of cancers.




Division

Field of Study

Instructors

Major Subject


Evaluation

Evaluation Criteria



Evaluation

Evaluation Criteria



Evaluation

Evaluation Criteria



Evaluation

Evaluation Criteria



Internal Medicine

Hematology

Yoshio Katayama, MD, PhD

To obtain the skill to deeply understand scientifically important papers. The students willpresent research results in our research meetings and the both domestic and internationalacademic conferences to improve the presentation skills.

active participation in the research and the outcome

Theme and ObjectivesExperimental Medicine: To proceed experiments and learn molecular biology, biochmistry, cellbiology, and genetics. Clinical reserach: To learn how to make a clinical study design whichcan be approved by Internal Review Board (IRB), and proceed through patient care. Bothexperimental and clinical research: To learn data analysis and medical statistics, and writingpapers.

active participation in the research and the outcome







Hematology

Theme and ObjectivesTo acquire basic skills to extract essential questions through the careful observation ofpatients with hematologic diseases. To learn how to appproach those questions clinically andscientifically, including the assessment of published papers, laboratory activity, and patientcare.



active participation in the practice and the outcome

Theme and Objectives1) To obtain the skills to care patients with molecular targeted drugs, chemo/immunotherapy,cell therapy together with supportive cares, which require for approved hematologist.2) To understand how important it is to care patients in an IRB approved clinical study.3) To be clearly aware of ethics/morals because many hematologic diseses are lifethreatening.

active participation in the seminar and the outcome


Division

Field of Study

Instructors

Major Subject


2) To learn X-rays dissection and pathologic anatomy for diagnostic imaging

Evaluation

Evaluation Criteria



1) To learn the imaging of various organs and the progress of the imaging in those organs2) To learn the latest finding of the diagnostic imaging in various organs3) To learn the clinical inspection method and clinical application of the utility in the imaging4) Preparation of manuscripts for submission to international and top journals in this field

Evaluation

Evaluation Criteria



Evaluation

Evaluation Criteria



1) To apply diagnostic imaging techniques in routine clinical practice and clinical study2) To aquire image interpretation skills in clinical practice

Evaluation

Evaluation Criteria



Results of oral test

Level of research report




1) To learn presentation skill for research results at international meeting2) To learn discussion and debate skills for research results presentation at internationalmeeting





Internal Related

Radiology

Koji Sugimoto, Takaki Maeda, Masato Yamaguchi, Munenobu Nogami, KeitaroSofue



Radiology





We conduct the systematic lecture along the following objectives and make use of it in thebedside teaching in the 2nd semester.

3) To learn the representative cases of the imaging in various diseases and build the basics ofclinical studies

1) To learn an imaging device and the imaging principle becoming basic of various imagediagnostics


Division

Field of Study

Instructors

Major Subject


Evaluation

Evaluation Criteria



Evaluation

Evaluation Criteria



Evaluation

Evaluation Criteria



Evaluation

Evaluation Criteria




Theme and Objectives1) To learn basic research methods for functional and diagnostic imaging research2) To learn basic research methods for computer-aided diagnosis research3) To learn state of the art for chest and abdominal diagnostic radiology and functional imaging4) To learn state of the art for computer-aided diagnosis5) Preparation of manuscripts for submission to international and top journals in this field


Internal Related

Radiology/Functional and Diagnostic Imaging Research

Yoshiharu Ohno, Sumiaki Matsumoto, Takeshi Yoshikawa, MizuhoNishio

Functional and Diagnostic Imaging, Computer-Aided Diagnosis

Theme and Objectives1) To learn foundations of image science for diagnostic imaging2) To learn basic mathematical models for functional and diagnostic imaging research3) To learn anatomy and basics for imaging technique


Theme and Objectives1) To apply functional and diagnostic imaging techniques in routine clinical practice and clinicalstudy2) To apply methodologies of computer-aided diagnosis in clinical study and clinical practice3) To apply chest and abdominal diagnostic and functional imaging analysis for clinical study









Theme and Objectives1) To learn presentation skill for research results at international meeting2) To learn discussion and debate skills for research results presentation at internationalmeeting


Division

Field of Study

Instructors

Major Subject


Evaluation

Evaluation Criteria



Evaluation

Evaluation Criteria



Evaluation

Evaluation Criteria



Evaluation

Evaluation Criteria



Theme and ObjectivesThe students learn to design and write a research protocol and participate in the dataacquisition and analysis for molecular imaging research activity to generate a research article.



Internal Related

Molecular Imaging / Radiology

Michio Senda





Clinical skill and team work.

Theme and ObjectivesThe students participate in the clinical research activities regarding molecular imagingperformed in Institute of Biomedical Research and Innovation and practice patient procedure,radionuclide handling, PET scanning and other skills.

Presentation and discussion skill.


Theme and ObjectivesThe students participate in the internal conferences of the Division of Molecular Imaging,Institute of Biomedical Research and Innovation, and learn to present and discuss researchdata with associates.

Research report, abstract, or full paper.

Report on PET basics

Molecular Imaging

Theme and ObjectivesThe students learn the basic principles and techniques for visualizing functions of the brain,tumor, and other organs using PET and other molecular imaging methods.


Division

Field of Study

Instructors

Major Subject


Evaluation

Evaluation Criteria



Evaluation

Evaluation Criteria



Evaluation

Evaluation Criteria




Evaluation according to students knowledge about basics ofradiation oncology




Evaluation of research reports

Theme and ObjectivesPurpose:Understanding the basic methods of radiation treatment planning.Outiline: Practicing three dimensional treatment planning including image fusion, treatmentverification and dose calculation. The goal is to complete radiation treatment planningsaccurately tobe applied in daily clinical practice.

Evaluation according to students knowledge about individualizedtreatment planning


Ryohei Sasaki, Kenji Yoshida, Daisuke Miyawaki, Takeaki Ishihara,Hiroaki Akasaka

Theme and ObjectivesPurpose:Understanding radiation therapy for each disease specifically.Outiline: Learn about the indication, dose/fractionation and radiation dose of each disease,such as head and neck cancers, lung cancers, esophageal cancers qand brain tumors.

Purpose:Understanding the basic theories of radiation oncology.Understanding curative and palliative radiation therapy.Outiline: To understand the basic theories of radiation oncology, radiation biology and radiationphysics, and to understand the tolerance dose of organs at risks as well as curative dose oftumors based on diagnostic imaging.

Internal Related

Radiation Oncology


Radiation Oncology


Division

Field of Study

Instructors

Major Subject


Evaluation

Evaluation Criteria



Evaluation

Evaluation Criteria



Evaluation

Evaluation Criteria



Evaluation

Evaluation Criteria


Accomplishment of objectives

To read papers on diseases in childrenTo develop communication skill


Internal Related

Pediatrics

Kazumoto Iijima et al.


Pediatrics

Theme and ObjectivesTo study the diagnosis and treatment on diseases in children







Theme and ObjectivesTo write papers on diseases in childrenTo study clinical trials in children for the development of new therapies




Theme and ObjectivesTo extract problem lists on diseases in children and resolve the problems



Division

Field of Study

Instructors

Major Subject


Evaluation



Evaluation



Evaluation



Evaluation


Pediatrics

Theme and ObjectivesTo study the diagnosis and treatment on diseases in children



Internal Related

Pediatrics / General Pediatrics

Kazumoto Iijima, et al.



Theme and ObjectivesTo write papers on diseases in childrenTo study clinical trials in children for the development of new therapies



Theme and ObjectivesTo read papers on diseases in childrenTo develop communication skill





Theme and ObjectivesTo extract problem lists on diseases in children and resolve the problems in the clinical fields




Division

Field of Study

Instructors

Major Subject

Title Special Lecture Ⅰ ６ credits Semester

Evaluation

Evaluation Criteria

Title Special Lecture Ⅱ ４ credits Semester

Evaluation

Evaluation Criteria


Evaluation

Evaluation Criteria

Title Practice ２ credits Semester

Evaluation

Evaluation Criteria

Theme and ObjectivesTo read papers on pediatric development.To develop cmmunication skills on pediatric development.




Theme and ObjectivesTo extract problems on pediatric development.To learn how to resolve problems on pediatric development.



To study what is normal and abnormal development in children.


Theme and ObjectivesTo study how to write a paper on pediatric development.




Internal Related

Developmental pediatrics/Pediatrics

Noriyuki Nishimura, et al.

Normal and abnormal development in children


Division

Field of Study

Instructors

Major Subject


Evaluation

Evaluation Criteria



Evaluation

Evaluation Criteria



Evaluation

Evaluation Criteria



Evaluation

Evaluation Criteria






Methods to propose the hypothesis for clarifying unsolved questions in dermatoses and interpretthe results logically will be educated. In addition, the way to write papers using these results will beinstructed.

absolute assessment

absolute assessment

Theme and ObjectivesA way of thinking for making a diagnosis in dermatology and techniques of clinical tests for thediagnosis will be instructed based on clinical experiences.

absolute assessment




absolute assessment


Through discussing papers and making presentations of obtained data, an ability of readingcomprehension and a skill of making presentations on the research will be developed.



Theme and ObjectivesThe concept and fundamental knowledge of dermatology will be educated. Methods to clarify itsquestions will be instructed.


Internal Related

Dermatology

Chikako Nishigori, Masahiro Oka, Hiroshi Nagai, Toshinori Bito, HiroshiNagai, Atsushi Fukunaga

Dermatology

Division

Field of Study

Instructors

Major Subject


Evaluation



Evaluation



Evaluation



Evaluation


Psychiatry

Theme and ObjectivesWe aim at mastering thatbasic clinical and biological study skills and knowledges aboutpsychiatric disorders. It includes clinical examination skills, interview skills, neurologicalexamination skills and so on.

Written Test　　　・　　○Oral Test　　　・　　○Research Report


Internal Related

Psychiatry

I .Sora, K. Tanaka, A. Hishimoto, T. Hashimoto, T. Kawamata

Archievement of aims


Theme and ObjectivesWe aim at mastering that advanced clinical and biological skills and knowledges aboutpsychiatric disorders. We read journal articles, and learn techniques of paper writing.



Theme and ObjectivesWe aim at mastering that advanced clinical and biological skills and knowledges aboutpsychiatric disorders by reading current journal articles, And practice presentations.

Required readind original English text books and articles

Required reading articles and writing English repots

Required speaking English


Theme and ObjectivesThe target of this subject is enhancing the capability to clinical examination techniques.Therefore, we can also choose training in professional medical organization.



Required writing English reports

Division

Field of Study

Instructors

Major Subject


Evaluation

Evaluation Criteria



Evaluation

Evaluation Criteria



Evaluation

Evaluation Criteria



Evaluation

Evaluation Criteria


Notified at the time of practice.


Theme and ObjectivesIn this course, students are expected to learn and participate in the daily practice in the fieldof Rheumatology, blood transfusion and laboratory medicine. Based on the knowledge acquiredin the above courses, students are expected to become highly skilled person in their field.



Notified at the time of seminers.

Evaluation Criteria includes an original paper and/or oralpresentation at a scientific meeting.


Theme and ObjectivesThe objectives of this course is to learn advanced knowledge and techniques in the field oflaboratory medicine, clinical immunology and blood transfusion. Also how to write a scientfivpaper will be lectured. The goal of the course is to present the data in a scientific meeting andto write an original paper.



Theme and ObjectivesThe objectives of this course is to learn how to present your own data in an oral and posterpresentation. Also how to communicate with other people in a meeting wiil be learned.

Notified at the time of lectures.

Notified at the time of lectures.

Laboratory Medicine

Theme and ObjectivesThe objectives of this course is to learn basic knowledge and techniques in the field oflaboratory medicine, clinical immunology and blood transfusion. The course includes how toread scientific articles, how to design experiments, and how to interpretate the experimentalresults.



Internal Related

Laboratory Medicine

S. Kawano, J. Saegusa

Division

Field of Study

Instructors

Major Subject


Evaluation



Evaluation



theme and Objectives



Evaluation


Metabolomics Research

Theme and ObjectivesIn this lecture, to understand the omics(Metabolomics and Proteomics) for disease diagnosis,you learn the basic knowledge and skill of the analysis technology using mass spectrometer,and then understand the clinical significance.



Internal Related

Metabolomics Research

Masaru Yoshida

It will be evaluated by achivement of research report.


Theme and ObjectivesIn this lecture, you analyze various diseases by omics technology (Metabolomics andProteomics), and investigate the target molecules. The goal is to lead research results toelucidation of novel clinical status and advanced medical technology, and also to prepareyour paper manuscripts based on the research results.



Theme and ObjectivesIn this lecture, you understand articles about metabolomics, and evaluate the validity of thearticles and their future adaptation. In addition, you aim at developing a communication skill bythe presentation including own study introduction.





Theme and ObjectivesIn this lecture, you understand highly advanced medical technology using the metabolomics,and aim at developing new advanced medical care.




Division

Field of Study

Instructors

Major Subject


Evaluation

Evaluation Criteria



Evaluation



Evaluation



Evaluation


Instracted during the term



Internal Related

Palliative Medicine

Hironobu Minami, Yoshiyuki Kizawa, Akihiro Sakashita, TakashiYamaguchi.

Palliative Medicine



Objectives・To understand concepts of palliative medicine・To describe the methods for multi-dimentional assessment (bio-psychosocial-spiritualsuffering) and basic management for patients and families facing life threatening illness.


Theme and Objectives・To plan clinical research or survey in palliative medicine based on clinical question・To collect and analyse data for clinical research・To write a paper in palliative medicine

It will be evaluated based on the degree of achievement ofacquiring basic knowledge in palliative medicine.

Theme and Objectives・To acquire skills for critical appraisal of scientific papers and presentation in scientificmeeting in Japanese and English・In the journal club, students are required to introduce important papers based on criticalaprraisal.・In the research meeting, students are required to present a progress in their own researchproject.・Students are required to present their research outcome in scieintific meeting.

It will be evaluated based on reports, presentation or writtenpapers.


It will be evaluated by clinical observation.

Theme and ObjectivesTo demonstrate multi-dimentional assessment (bio-psychosocial-spiritual suffering) andmanagement for patients and families facing life threatening illness.To demonstrate skills for specialist consultation in palliative medicine.

It will be evaluated by achievement of research reports.




Division

Field of Study

Instructors

Major Subject


Evaluation



Evaluation



Evaluation



Evaluation



Make a comprehensive assessment through basic and clinical practice.

Theme and ObjectivesBasic training for the tailor-made pharmacotherapy. According to genotyping,practice anddiscuss about the most relevant pharmacotherapy with other health care professionals.

Evaluate the seminar report.



Make a comprehensive assessment through research reports.


Theme and ObjectivesThe current research projects are as follows:(1) Drug optimal usage(2) Pharmacokinetics and pharmacodynamics(3) Personalized pharmacotherapy based on genotyping(4) Development of mechanism-based preventive methods for adverse reactions induced by moleculartargeted therapyCreate a paper based on the research results.

Oral test for assessment of the basic knowledge.


Theme and ObjectivesTo establish the basic knowledge for our research projects,fostering the comprehension ofresearch papers. Attend the seminar or workshop for development of the communication skillswith other healthcare proffessionals.



Pharmaceutics

Theme and ObjectivesThe goal of our research is to elucidate clinical applications for the optimalpharmacotherapy.The aim of this research is to acquire basic knowledge and skills fordeveloping the effective and safe pharmacotherapy by means of validating thepharmacokinetics and genotype as well as various medical bioinformatics available.




Pharmaceutics

Ikuko Yano, Tsutomu Nakagawa, Toshiyasu Sakane

Division

Field of Study

Instructors

Major Subject

Title Special Lecture Ⅰ ６ credits Semester 1st & 2nd

Evaluation


Title Special Lecture Ⅱ ４ credits Semester 1st & 2nd

Evaluation


Title Seminar ３ credits Semester 1st & 2nd

Evaluation


Title Practice ２ credits Semester 1st & 2nd

Evaluation


pediatrics

Theme and ObjectivesTo study the diagnosis and treatment on diseases in children at Kobe Children's Hospital

Written Test　　　・　　　Oral Test　　　・　○　Research Report


pediatrics

advanced pediatrics

Y.Kosaka, H.Nakao, etc


Written Test　　　・　○Oral Test　　　・　○Research Report

Theme and ObjectivesTo write papers on diseases in childrenTo study clinical trials in children for development of new therapies


Written Test　　　・　　　Oral Test　　　・　○Research Report

Theme and ObjectivesTo read papers on diseases in childrenTo develop communication skill





Theme and ObjectivesTo extract problem lists on diseases in children and resolve the problems


Written Test　　　・　○Oral Test　　　・　　　Research Report


Division

Field of Study Gastro-intestinal Surgery

Instructors

Major Subject Gastro-intestinal Surgery


Evaluation

Evaluation Criteria



Evaluation

Evaluation Criteria



Evaluation

Evaluation Criteria



Evaluation

Evaluation Criteria


Theme and ObjectivesThe theme and objectives are to understand the pathology including molecular biologicalaspects and study the basic knowledges and skills about diagnosis and treatment of surgicaloncology and the inflammation. We encourage the ability to analyze the informationscientifically. Furthermore, we instruct standard surgical treatments of the esophageal cancer,gastric cancer and colorectal cancer technically.



Surgery

Yoshihiro Kakeji

To master the advanced knowledges and skills about diagnosis and treatment inthe field of gastrointestinal surgery. To report the results as a paper.


Theme and ObjectivesThe theme and objectives are to research to elucidate cancer pathology and to establish anovel diagnosis and treatment in the field of gastrointestinal surgery focused on esophagealcancer, gastric cancer and colorectal cancer. Furthermore, the results of these studies arepresented at a research conference and reported as a paper.

To master the basic knowledges and skills about diagnosis andtreatment in gastrointestinal surgery.


Theme and ObjectivesThe objectives are to extract the problems of standard diagnostic and therapeutic methodsfor staging of gastrointestinal cancer, especially esophageal cancer, gastric cancer and coloncancer. The second is to acquire the communication skills by accumulating and decipheringthe latest knowledge from suitable papers and is to refine the skills to analyze these problems,and to make presentation at conferences. The third is to decide the surgical managementappropriately for patients in various stages and conditions.




To acquire essential diagnostic and therapeutic techniques for surgicaloncology and understand the significance of clinical trials as a gastrointestinalsurgeon.

Theme and ObjectivesThe objectives are to undergo minimally invasive surgery in the field of gastrointestinalsurgery focused on esophageal cancer, gastric cancer and colorectal cancer. In addition, weprovide opportunities to learn surgical operations, as well as multidisciplinary treatmentscombined with chemotherapy such as radiotherapy, anticancer drugs, and molecular targetedtherapeutic agents, and to involve in clinical trials of advanced medicine.

To master the advanced knowledges and skills about diagnosis and treatment inthe field of gastrointestinal surgery. To report the results as a paper.



Division

Field of Study

Instructors

Major Subject


Evaluation

Evaluation Criteria


Evaluation

Evaluation Criteria


Evaluation

Evaluation Criteria


Evaluation

Evaluation Criteria Report could be also evaluated.

Theme and ObjectivesThe aim of the practices is to perform the translational research on the leading-edgetreatments such as liver transplantation, islet/pancreas transplantation, laparoscopic surgery,PIHP and particle beam radiation therapy with a mentor.

Report could be also evaluated.


Theme and ObjectivesThe aim of the seminars is to understand the pathophysiology of Hepato-Biliary-Pancreaticdiseases, to develop the skills to analyze the problems on the novel diagnostics andtreatments by discussing, and to acquire how to evaluate the results and to write an articlewith a mentor.



Theme and ObjectivesThe aim of the lectures is to learn liver transplantation, islet/pancreas transplantation,laparoscopic surgery, PIHP and particle beam radiation therapy. It is additionally to learn theregeneration medicine and gene therapy expected to have the potential to treat Hepato-Biliary-Pancreatic diseases in the near future. The lectures are especially focused onresearching the pathological conditions and treatments associated with Hepato-Biliary-Pancreatic diseases based on the research plans developed in the Special Lecture I/II, andwriting an article.



Hepato-Biliary-Pancreatic Surgery

Theme and ObjectivesThe aim of the lectures is to learn the surgical diagnostics and treatments of Hepato-Biliary-Pancreatic diseases. The lectures are especially focused on learning the clinical anatomy andpathophysiology by comparing with the practical techniques required for the surgery.



Surgery

Hepato-Biliary-Pancreatic Surgery

Takumi Fukumoto

Division

Field of Study

Instructors

Major Subject


Evaluation

Evaluation Criteria



Evaluation

Evaluation Criteria



Evaluation

Evaluation Criteria



Evaluation

Evaluation Criteria




Theme and ObjectivesThe aim of the seminars is to understand the diagnoses and treatments procedures of breastcancers, to develop the skills of communication by the case presentations and discussions,and to acquire how to evaluate the results of clinical trials and translational researchs and towrite an article with a mentor.

by the results of oral tests and in the lectures and contents ofwritten papers


by the results of oral tests and reports in the practices

Theme and ObjectivesThe aim of the practices is to learn about the commimucation to the patients with breastcancers, the clinical interventions for diagnoses of breast cancers, and the Sentinel lymphnodes biopsy and surgical approarches with curability and cosmesis. It is also to leran howto perform the appropriate drug therapies for each patients with breast cancers and how topractice the team treatment with community cooperation for the patients with metastaticbreats cancers.

by the results of oral tests and reports in the seminar






Surgery

Breast Surgery

Sintaro Takao, Seishi Kohno

Breast Surgery

Theme and ObjectivesThe aim of the lectures is to learn the diagnostics and treatments of breast diseases. Thelectures are especially focused on learning the multidisciplinary approach to diagnose andtreat the patients with breast cancers.


Theme and ObjectivesThe aim of the lectures is to learn about up-to-date imaging diagnosis procedures for breastdiseases. It is also to aquire the newest oncoplastic surgical procedures with curability andcosmesis cooperated with plastic surgeons. It is to understand development of the newbiomarkers and mechanism of new target therapies. Finally, the lectures give the skills tomake the research plans for breast diseases developed in the Special Lecture I/II, and writingan article.

by the results of oral tests and research reports in the lectures

Division

Field of Study

Instructors

Major Subject


Evaluation

Evaluation Criteria



Evaluation

Evaluation Criteria



Evaluation

Evaluation Criteria



Evaluation

Evaluation Criteria




Aortic surgery (aortic arch and thoracoabdominal aorta) and endovascular aortic repair mustbe understood and learn the mechanism of spinal cord ischemia. Presentation at researchconference is performed at each semester. Research paper on spinal cord protectoin is mustbe completed at the end of the course

Theme and ObjectivesBasic research on 1 of the following themes is chosen; 1) aortic aneurysm: cerebral ischemiain aortic dissection, spinal cord ischmia in thoracoabdominal surgery, and hemodynamics inaortic root surgery; 2) control release of drugs using hydrogel: strengthen vascular wall andprevent graft degradation; 3) invention of small caliber graft; 4) cardiopulmonary bypass.

present a report at research conference




minimum of 50 points

Theme and ObjectivesBasic surgical skills and perioperative care in open heart surgery must be learned.



Theme and ObjectivesThe aim of this course is to understand general sugery, especially surgical stress andresponse of the body. As for cardiovascular surgery, students must learn about valvular ,ischemic heart , aortic and peripheral artery diseases. In addition, students need tocomprehend the system of cardiopulmonary bypass, which maintains the circulation of bloodand the oxygen content of the body during open heart surgery, and be able to troubleshoot.




Surgery

Cardiovascular Surgery

Yutaka Okita

Cardiovascular Surgery



Division

Field of Study

Instructors

Major Subject


Evaluation

Evaluation Criteria



Evaluation

Evaluation Criteria



Evaluation

Evaluation Criteria



Evaluation

Evaluation Criteria



The achievement is judged comprehensively.

Theme and ObjectivesStudents will learn Multidisciplinary treatment ageinst primary lung cancer in Kobe UniversityHospital and Hyogo Cancer Center.





Carrying out the presentation of the newest paper will give you expression, reading, andpersuasive ability.



Gene mutations and their expression disorder in lung cancer are analysed with surgicalspecimens and the relationship with clinico-pathological findings is evaluated.




Diagnostic methods and medical treatment for respiratory diseases are lectured．






Surgery

Thoracic Surgery

Yoshimasa Maniwa

Thoracic Surgery

Division

Field of Study

Instructors

Major Subject


Evaluation

Evaluation Criteria



Evaluation

Evaluation Criteria



Evaluation

Evaluation Criteria



Evaluation

Evaluation Criteria



There must be regular discussions of problems in clinical investigations or experimentalresearch.


We assess the level of achivement comprehensively.



Surgery

Pediatric Surgery

Eiji Nishijima, Chieko Hisamatsu

Pediatric Surgery



Theme and ObjectivesProgram should be incorporated with: (1) surgical techniques and endoscopic techniques, (2)preoperative and postoperative care.





Graduate students will research on (1) minimally invasive procedures of thoracic andabdominal surgery, (2) strategy for refractory pediatric disorders (airway disease andoncology), (3) organ transplantation using tissue engineering techniques, (4) development ofartificial internal organ for neonate.



Graduate students are expected to have a knowledge and understanding of: (1) basicsciences including genetics, embryology, anatomy, physiology, biochemistry, pathology, andphamacology, (2) clinical behavior, diagnosis and treatment of diseases in pediatric surgery.




Division

Field of Study

Instructors

Major Subject


Evaluation

Evaluation Criteria



Evaluation

Evaluation Criteria



Evaluation

Evaluation Criteria


Title Practice ２ credits Semester 1st

Evaluation

Evaluation Criteria





Theme and ObjectivesEtiology, basic science, and treatment for musculoskeletal disorders will be presented, andcorrelations between these diseases and clinical anatomy, physiology, pathology will be alsolectured. Based on the latest insights in the orthopaedics research, contemporary imaginganalysis and surgical techniques will be introduced, and research techniques will be alsopresented.

Evaluation by interview and reports to test the achivement.

Theme and ObjectivesThe aims of this practice are (1) to learn diagnostic methods to evaluate musculoskeletaldisorders and trauma and planning techniques for treatment, (2) to learn indications fororthopaedic surgeries, basic techniques of surgery, post-operative treatment, andrehabilitation.



Theme and ObjectivesThe aim of this seminar is to learn how the information of a living body can be detected tounderstand the situation of the disease and how the information can be interpreted fortreatment. The students also learn the skills for communication by reading published articlesand performing oral presentation.






The aims of this lecture are (1) to learn the latest knowledge and techniques of imaginganalysis and biomechanics to understand correlations between musculoskeletal disorders andpathological changes, (2) to learn editorial techniques of writing a manuscript for presentationof the results.




Surgery Related

Orthopaedics

Ryosuke Kuroda, Kotaro Nishida, Takahiro Niikura, Takehiko Matsushita, Tomoyuki Matsumoto

Orthopaedics

Division

Field of Study

Instructors

Major Subject


Evaluation

Evaluation Criteria



Evaluation

Evaluation Criteria



Evaluation

Evaluation Criteria



Evaluation

Evaluation Criteria




Theme and ObjectivesThe aims of this practice are to learn treatment methods to evaluate impairment and toindicate for orthosis, physical, occupational and speech therapy.



Theme and ObjectivesThe aim of this seminar is to learn how the information of a living body can be detected tounderstand the situation of the impairment, and how the information can be interpreted fortreatment. The students also learn the skills for communication by reading published articlesand performing oral presentation.





Theme and ObjectivesThe aims of this lecture are (1) to learn the latest knowledge and techniques of imaginganalysis, electro-physiological examination and biomechanics to understand correlationsbetween impairment and pathological changes, (2) to learn editorial techniques of writing amanuscript for presentation of the results.




Rehabilitation Medicine

Theme and ObjectivesEtiology, basic science, and treatment for rehabilitation medicine will be presented, andcorrelations between these diseases and clinical anatomy, physiology, pathology will be alsolectured. Based on the latest insights in the rehabilitaion research, contemporary imaginganalysis and electro-physiological examination and evaluation technique will be introduced, andresearch techniques will be also presented.



Surgery Related

Rehabilitaion Medicine

Yoshitada Sakai

Division

Field of Study

Instructors

Major Subject


Evaluation

Evaluation Criteria



Evaluation

Evaluation Criteria



Evaluation

Evaluation Criteria



Evaluation

Evaluation Criteria



Basic knowledge and skills are obtained for neurosurgicaldiagnostics and treatments.

Theme and ObjectivesImprove diagnostic ability through clinical cases in the neurosurgical ward. Aquire basicmicrosurgical technique in the operating theater.

Appropriate presentation can be done in the conference andjournal club



Enough advanced knowledge and skills are aquired and scientificpapers are completed.


Theme and ObjectivesLearn advanced knowledge and skills on pathophysiology, diagnostic methods and treatmentmodalities of various neurosurgical diseases. Basic and clinical research work should beperformed to make scientific papers.

Enough basic knowledge and skills are aquired onpathophysiology, diagnostics and therapies


Theme and ObjectivesCommunication ability is obtained through clinical conference and journal club



Neurosurgery

Theme and ObjectivesLearn basic knowledge and skills on pathophysiology, diagnostic methods and treatmentmodalities of various neurosurgical diseases. Basic knowledge will be also obtained onmolecular biological or genomic aspects of neurosurgical disorders.



Surgery related

Neurosurgery

Kohmura E, Taniguchi M, Sasayama T, Fujita A

Division

Field of Study

Instructors

Major Subject

Title Special Lecture Ⅰ ６ credits Semester all

Evaluation

Evaluation Criteria

Title Special Lecture Ⅱ ４ credits Semester all

Evaluation

Evaluation Criteria

Title Seminar ３ credits Semester all

Evaluation

Evaluation Criteria

Title Practice ２ credits Semester all

Evaluation

Evaluation Criteria

Ophthalmology

Theme and ObjectivesTo learn the experimental skills to investigate the mechanisms of pathogenesis of oculardiseases and to earn clinical updated knowledge in ophthalmology.

Written Test　　　・　　○　Oral Test　　　・　　　Research Report


Ophthalmology

Clinical and basic eye research

Nakamura M, Honda S, Yamada Y, Kusuhara S, Kurimoto T, Miki A

The presentation to assess the level of achievement theirunderstanding and knowledge earned about scientific informationon recent progress in the research of ocular diseases.

Written Test　　　・Oral Test　　　・　　　　○　　Research Report

Theme and ObjectivesOn the basis of the knowledge obtained in Special Lectue I, the experimental design will beconstructed to develop a novel approach. The experimental results should be reported ininternational scientific journals.

The achievement will be evaluated to assess their understandingand knowledge earned about scientific information on recentprogress in the research of ocular disease.

Written Test　　　・　　　Oral Test　　　・　　　○　Research Report

Assesment their clinicall skills and techniques acquired during thecourse

Theme and ObjectivesTo experience and obtain the recent techniques on the diagnosis and the treatment in theoutpatient clinic under the supervison.

The presentation including discussion at the meetings to assessthe level of achievement in the PhD research.

Written Test　　　・　　　○　Oral Test　　　・　　　Research Report

Theme and ObjectivesTo understand the recent progress in the research of ocular diseases and to achieve the skillsfor their effective presentation.

Division

Field of Study

Instructors

Major Subject

Title Special Lecture Ⅰ ６ credits Semester whole year

Evaluation

Evaluation Criteria


Title Special Lecture Ⅱ ４ credits Semester whole year

Evaluation

Evaluation Criteria



Evaluation

Evaluation Criteria


Title Practice ２ credits Semester whole year

Evaluation

Evaluation Criteria




Theme and ObjectivesTheme: Communication Skills and Clinical Reseach in Otolaryngology-Head and Neck SurgeryObjective: At the completion of this unit, the resident can discuss the nonsurgical andsurgical management of diseases and disorders in general otolaryngology

The student can perform a comprehensive history and physicalexamination, order appropriate laboratory and diagnostic testing,develop a differential diagnosis, and arrive at a diagnosis ofintractable diseases and disorders in Ootolaryngology-Head andNeck Surgery.


The resident can perform neck dissection, endoscopic nasalsurgery, microlaryngosurgery and mastoidectomy under thementorship of instructors.

Theme and ObjectivesTheme: Surgical Skills in Otolaryngology-Head and Neck Surgery.Objectives: At the end of the end of this unit, the resident can perform the standard surgicaltechniques for general diseases and disorders in Otolarygology-Head and Neck Surgery.

The resident can present case reports at academic meeting.






Department of Surgery Related

Division of Otolaryngology-Head and Neck Surgery

Ken-ichi Nibu, MD, PhD

Otolaryngology-Head and Neck Surgery

Theme and ObjectivesTheme: General Diseases and Disorders in OtolaryngologyObjectives: At the end of this unit, the student can recognize, assess diagnose and managethe the diseases and disorders in General Otolaryngology.


Theme and ObjectivesTheme: Intractable Diseases and Disorders in Otolaryngology-Head and Neck SurgeryObjectives: At the end of this unit, the student can recognize, assess diagnose and managethe the intractable diseases and disorders in Otolaryngology-Head and Neck Surgery.

The student can perform a comprehensive history and physicalexamination, order appropriate laboratory and diagnostic testing,develop a differential diagnosis, and arrive at a diagnosis ofdiseases and disorders in General Otolaryngology

Division

Field of Study

Instructors

Major Subject


Evaluation

Evaluation Criteria



Evaluation

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Evaluation

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Evaluation

Evaluation Criteria




Theme and ObjectivesThe purpose of this seminar is to get the presentation skills and paper-writing skills inurological field.

60%


Report

Theme and ObjectivesYou learn diagnosis, treatment and management of urologic diseses. Topics are "Roboticsurgery", "Laparoscopic surgery", "Artificial reproductive therapy", "Molecular targetedtherapy for renal cancer", "Renal transplantation", and "Laser in urologic field".

60%






Surgery Related

Urology

Masato Fujisawa

Urology

Theme and Objectives"From bed to bench" and "From bench to bed" are the aim of the research in ourdepartment. You learn Urologic oncology, Urolithiathis, Urinry tract infection, ED, Voidingdysfunction, Pediatric urology, Female urology, renal failure, renal transplantation.


Theme and ObjectivesYou learn advanced medicine in urological field. Topics are "Gene therapy for prostatecancer", Cell to cell interaction in testis", and "Mechanism of antimicrobial resistance inurogenital infection".

60%

Division

Field of Study

Instructors

Major Subject


Evaluation



Evaluation



Evaluation



Evaluation


Obstetrics and Gynecology

Theme and ObjectivesTo understand human reproduction and reproductive systems.To learn basic knowledge and skills needed to treat patients in Obstetrics, Gynecology,Reproductive health, ane Women's health.



Surgery Related

Obstetrics and Gynecology

Hideto Yamada, Yasuhiko Ebina, Masashi Deguchi, KenjiTanimura, Mayumi Morizane

Judgment of acceptance will be determined by research paper andattitude.


Theme and ObjectivesObstetrics: To understand natural immunity during conception and fetal development. Creating novelstrategy for unexplained recurrent miscarriage. To elucidate pathological condition in prenatal infection.To establish safe cesarean section in patients with placenta previa. To create novel management forthe pregnancy with complication.Gynecologic oncology: To assess clinicopathological factors in patients with gynecologic malignancies.To develop radical surgery with functional preservation for gynecological cancer.Reproductive health: To understand pathophysiology of conception and infertility, To create novelstrategy for infertility.Womens' health: To create novel management of pelvic organ prolapse. To establish novel therapiesfor congenital abnormality of the genitalia, Development of new therapy for sexually transmitteddiseases.

Judgment of acceptance will be determined by research paperand attitud


Theme and ObjectivesTo review the topics of research, and report the progress of the research regularly.





Theme and ObjectivesTo perform medical care in Perinatal medical center and Ob/Gyn ward. To instruct medicalstudents or residents.




Division

Field of Study

Instructors

Major Subject


Evaluation

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Evaluation

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Evaluation

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Evaluation

Evaluation Criteria




Theme and ObjectivesTo study of histological assessment in nerve regeneration after the microsurgical anastomosis

acquisition of progressive skill and development of paper


acquisition of practical application

Theme and ObjectivesClinical trial of microsurgical method of a nerve transfer between facial and sublingual nerves

acquisition of reading comprehesion and presentation skill






Surgery Related

Plastic and Reconstructive Surgery

Hiroto Terashi

Plastic Surgery

Theme and ObjectivesTo master the method of microsurgical transfer using wth the neurovascular anastomosis


Theme and ObjectivesTo clarify the mechanism of repair after the microsurgical transfer

acquisition of basic knowledement and skill

Division

Field of Study

Instructors

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Evaluation


Title Special Lecture Ⅱ ４ credits Semester 1st

Evaluation



Evaluation



Evaluation


Acceptance criteria is:Mastering expert knowledge and skills.



Theme and ObjectivesThe program develops the students' ability to evaluate and treat the patients withperioperative stress.Theme: Understand that adequate management of stress under anesthesia and intensive careaffects patient's prognosis.Objectives: ① Assess the statement of each patient under anesthesia and intensive careusing several parameters. ② Know that the reaction to medicine is respectively different.



Refer to Miller's Anesthesia(7th edi.). We indicate others during classes.

We indicate during classes.




Surgery Related

Anesthesiology and Perioperative MedicineSatoshi Mizobuchi, Yumiko Takao, Shinitiro Izuta, Takuyo Misumi, HitoakiSato, Moritoki Egi

Anesthesiology



The program develops the students' ability to evaluate and analyze parameters for biologicalreaction to stress.Theme: Study the mechanisms of protection against stress including operation and infection.Objectives: ① What is stress? Understand the mechanisms of stress. ② Elevate and analyzereactionｓ to stress. ③ Learn technique required in order to obtain the information fromseveral models.


Theme and ObjectivesThe program develops the students' knowledge and skills on preparation and accomplishmentof research with stress animal model.Theme: Observe the changes induced by stress of pain as operation, sepsis, hemorrhagicshock, etc. and protect the fuctions of major organs (brain, lung, liver, heart and kidney).Objectives: ① Prepare instruments for research and learn the technique. ② Learn how tomake animal models. ③ Understand assessments of stress.


Theme and ObjectivesThe program develops the students' ability to understand and interpret the scientific papers,and to discuss the problem with other reserchers.

Division

Field of Study

Instructors

Major Subject


Evaluation

Evaluation Criteria



Evaluation

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Evaluation

Evaluation Criteria



Evaluation

Evaluation Criteria



Written Test　　　・　　○　Oral Test　　　・　　○　Research Report


This course provides advanced knowledge and skills in oral and maxillofacial surgery. At thesame time students are required to write scientific paper.

attendance record, test result


Theme and Objectives This course intends to provide operation techniques and skills mainly in major surgery.







Students sre required to read important articles and to give their comments on the problems.Through this course communication skills are formed.



Theme and Objectives This course provides basic knowledge and skills in oral and maxillofacial surgery. The lecturesalso concern anomaly, deformity, injury, mucosal disease, inflammation, cyst and tumor of oraland maxillofacial region.


Surgery Related

Oral and Maxillofacial Surgery

Komori Takahide, et al.

Oral and Maxillofacial Surgery


Documents

（専門科目 / Major Subjects...平成30年度医科学専攻シラバス MEDICAL SCIENCE SYLLABUS 2018 （専門科目 / Major Subjects） 平成30年4月 / April2018 神戸大学医学部学務課

（専門科目 / Major Subjects...平成30年度医科学専攻シラバス MEDICAL SCIENCE SYLLABUS 2018 （専門科目 / Major Subjects）平成30年4月 / April2018 神戸大学医学部学務課