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Human Genes and Diseases

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Page 1: Human Genes and Diseases

Gene, 52 (1987) 297-303

Elsevier

297

GEN 01902

Rook Reviews

F. Blasi (Ed.): Human Genes and Diseases. [Vol. 8 of Horizons in Biochemistry and Biophysics, E. Quagliariello, Ed.] Wiley and Sons, Chichester and New York, 1986, xii + 676 pp. ($84.95) ISBN O-471-91 167-4.

(38 authors, 16 contributions. Linkage map of the X-chromosome; hemophilia A and B ; rare X-linked genes; DNA polymorphism; crossover points; HPRT genes; phosphoglycerate kinase gene; metal- lothionein gene regulation in Menke’s disease; j?-globin gene disorders in the Mediterranean area; hyperlipidemia; human collagens; human plas- minogen activators; in vitro transformation by acute retroviruses; monoclonal antibodies to the insulin receptors as probes; cellular oncogenes; patho- genesis of human cancer; human B-cell neoplasia; the e&-B-related growth factor receptors; aldolase gene; molecular pathophysiology).

G.H. Bourne and J.F. Danielli (Eds.): International

Review of Cytology, vol. 97, Academic Press, Inc., Orlando, FL, 1985, viii + 354 pp. ($52.5O/f46.00) ISBN O-12-364497-6.

[Molecular biology of higher plant mitochondrial DNA (Pring and Lonsdale); cell biology of the asialoglycoprotein receptor system: a model of receptor-mediated endocytosis (Breitfeld et al.); myosin isoenzyme transitions in muscle develop- ment maturation and disease (Bandman); the verte- brate yolk-platelet crystal: comparative analysis of an in vivo crystalline aggregate (Lange); invertebrate immunity: basic concepts and recent advances (Ratcliffe et al.)].

J. Brachet (Ed.): Molecular Cytology (Vol. 1, The Cell Cycle) Academic Press, Inc., Orlando, FL, 1985, xiii + 424, ($59.50, f52.00) ISBN 0-12- 123370-7.

[Five chapters (each followed by a list of references), 21 sections. Recent history of cytology; cytochemical approach-nucleic acids; optical, cyto- chemical and biophysical techniques; cell surface; cytoskeleton; membrane-bound cytoplasmic organ- elles; the GERL system; semiautonomous cell

organelles ; interphase nucleus; nuclear matrix; nuclear membrane and envelope; chromatin; nucle- olus; nucleoplasm; biochemical activities of isolated nuclei; the cell cycle; mitosis].

J. Brachet (Ed.): Molecular Cytology, Vol. 2, Cell Interactions. Academic Press, Inc., Orlando, FL 1985, xiii + 512 pp. ($69.50/f59.50 - hardcover; $39.95/f34.00 - paperback) ISBN 0-12-123379-

513-1. (17 chapters. Gene transfer in somatic cells: intact

cells, enucleation, hybrids, cybrids, DNA-mediated transformation. Nucleocytoplasmic interactions in oocytes and eggs: Xenopus oogenesis, maturation, fertilization of sea urchin anucleate eggs, cleavage, cytoplasmic and nuclear determinants. Cell differen- tiation, transformation, and aging: differentiation, transformation and malignancy, aging and death. Final remarks).

T.H. Carmen (Ed.): Cloning and the Constitution

(An Inquiry into Governmental Policymaking and Genetic Experimentation). The University of Wisconsin Press, 1985, xv + 223 pp. ($22.50). ISBN O-299-10340-4.

(A unique and excellent monograph covering the constitutional aspects of the ‘Great Recombinant DNA Debate’ and discussing: science in American constitutional history; cloning as American con- stitutional freedom; recombinant DNA debate as constitutional dialogue; cloners and their watch- dogs; recombining constitutional images; and three appendices: A. Respondent selection process. B. Questionnaire for recombinant DNA researchers. C. Questionnaire for institutional biosafety com- mittee chairmen).

Cold Spring Harbor Symposia on Quantitative

Biology, vol. XLIX, Recombination at the DNA Level. Cold Spring Harbor Laboratory, Cold Spring Harbor, NY, 1984, xxv + 852 pp. ($130.00) ISBN o-87969-049-6.

[Very important volume, obligatory for scientific workers in the field; 92 articles. Introduction: the