Hepler & Frank 71 Intraoccular Pressure_ JAMA

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    ID

    Minneapolis

    Marihuana Smoking and

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    Intraocular Pressure

    To the

    ment a bird whose name has become a

    household word in the 20th century,

    the barium swallow, Cousin of thebismuth swallow hatched in Walter

    Cannons laboratory, he is as white as

    the great arctic owl, although less air-

    worthy. He is a bland, but gritty fel-

    low with an atomic weight of 137, and

    his nickname is ambiguity.

    The point of this is that the world

    would be a better place if the barium

    swallow were extinct. His name on

    any x-ray film requisition prompts a

    flurry of telephone calls until the

    most appropriate of his many aliasescan be established in the case at hand.

    Sometimes it mean9 gastroin-

    testinal tract study or even small

    bowel study. In any case we wish he

    had never been conceived. He has

    generated more confusion than the

    combined imprecisions of the index of

    suspicion, the

    Barium Swallow

    Capistrano Revisited

    To the Editor.-Consider for a

    murmur, and the

    possible minimal pulmonary infil-

    trate.

    roscopy, but who can be sure? Barium

    swallow sometimes means

    the-heart usually means cardiac

    of the United States has called for a

    major effort to study drug effects in a

    scientific manner. In an attempt to

    investigate the effects of marihuana

    smoking upon the human visual sys-

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    tem, complete ocular examinations

    were performed in a group of youth-

    ful subjects, before and one hour

    1392

    is accepted widely

    that the physiologic effects of smok-

    ing marihuana are not well known,

    despite an acknowledged high in-

    cidence of usage. Even the

    September6, 1971

    l

    217,

    No 10

    arge percentage of

    within a period of thret

    nonths following the administratior

    dose of 250 mg four times a day. Ir

    in a later publication.

    Marihuana and Intraocular Pressure

    water pipe.

    It is our hope that further

    2 9 -22

    11 28 14 15 7 9 -45

    The purpose of this letter is

    intraocular pressure observed in

    far, namely, a substantial

    the

    tetracycline hydrochloride orally

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    to be high (0.9%). Two grams

    most impressive change

    mechanism of action, and

    3 28

    14 14 -27

    4 25 17 17 13 13 -23

    5 29

    rare entity whose lesions

    I

    2 23

    - 4 2

    9 27 15 15

    Progressive Telangiectasia:

    same experienced examiner

    6 26

    -30

    7 29 15

    of observations. Marihuana war

    possible implications, including

    39-year-old woman,

    and details

    noncontributory. The eruption

    the same tonometer for

    case report by Shelley,

    on the tops and sides of

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    tonometry was performed

    Health, and assays proved

    Treatment with Tetracycline

    by each

    25

    21 17 15

    physical examinations

    preliminary data concerning

    and dilated capillaries, had

    therapeutic action in

    a nd

    by the National Institute

    will be stimulated by

    of glaucoma, are obvious.

    of confluent areas of

    by clinicians and basic

    recorded in the Table

    of

    Treatment of

    a patient

    the protocol

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    13 13

    MD

    Los Angeles

    7

    of subjects

    11 -32

    using an ice

    R.

    by

    %

    dial function was recently reviewed

    in an editorial

    1971). Many

    reports of tion this with technique have more verified and elaborate its the good sensitivity

    correla-

    cardiac

    function tests. A potential appli-employment of cation left not ventricular suggested of serial heretofore ejection measurements

    is time

    the

    Letters

    indirect measure-

    ment of left ventricular ejection time

    intervals for assessment of

    laritis leading to telangiectasia and

    degenerative changes of the smallvessels.

    Since both our patient and Shelleys

    patient recovered following proce-

    dures capable of eliminating under-

    lying infections, the therapeutic ac-

    tion of tetracycline in Shelleys

    patient may have been due, after all,

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    to its broad-spectrum antibiotic ef-

    fect.

    Los Angeles

    Assessment of

    Cardiac Performance

    Syph

    Three had evidence of of focal Beckers infection, patients

    in-

    cluding mastoiditis, tonsillitis, prosta-

    titis, and dental infection.

    Our patient, a

    woman,

    had had her eruption for over a year

    and a chronic sinus infection for fouror five years, characterized by right

    antral pain, postnasal discharge, and

    frequent colds. Her eruption was

    widely scattered, being most severe

    on the upper part of

    trunk and

    arms, with nondescript or serpiginous

    areas of erythema and dilated capil-

    laries. The biopsy revealed a

    that it might have

    of dermatologic

    practice, which was apparently due

    a chronic sinus infection and which

    cleared completely following surgical

    eradication of this focus of infection,

    accompanied by

    cases of generalized telangiectasis

    reviewed by Becker, including four of

    his

    of some little-understood

    action rather than the

    usual wide-spectrum antibiotic effect,

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    although he speculated that a change

    be considered

    as a therapeutic mechanism.

    This report called to mind a similar

    case, the onlywhich I have seen

    in more than

    administration of

    an autogenous vaccine (Arch

    bowel

    the

    in

    must

    1932). This paper cited

    condition, feeling:

    of action

    the