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Instructional Design Book, Immunology and Infection Module, FMUI 2012 1 INSTRUCTIONAL DESIGN BOOK INFECTION AND IMMUNOLOGY MODULE Copyright 2012 by Faculty of Medicine of Indonesia all right reserved. This book or any parts there of may not used of reproduced in any manner without written permission from the writer/publisher. Printed in Jakarta, Indonesia ISBN 978-979-496-504-7 International Class Program Faculty of Medicine UNIVERSITY OF INDONESIA 2011/ 2012

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Instructional Design Book, Immunology and Infection Module, FMUI 2012

1

INSTRUCTIONAL DESIGN BOOK

INFECTION AND IMMUNOLOGY MODULE

Copyright 2012 by Faculty of Medicine of Indonesia all right reserved. This book or any parts there of may not used of reproduced in any manner without

written permission from the writer/publisher. Printed in Jakarta, Indonesia

ISBN 978-979-496-504-7

International Class Program Faculty of Medicine

UNIVERSITY OF INDONESIA 2011/ 2012

Instructional Design Book, Immunology and Infection Module, FMUI 2012

2

CONTENTS

Page

PREFACE 3 CHAPTER I : INTRODUCTION 4 Student Characteristic 5 CHAPTER II : Learning Objectives 6 CHAPTER III : Topics Discussion 7 CHAPTER VI : Teaching method 11 CHAPTER IV : Matrix Activity 13 Human resources 21

Facility 23 References 24 Chapter VI : Budget plan 26

CHAPTER VII : Evaluation of student results 28

Appendix 1 : Triggers 30 Appendix 2 : Duty & Responsibility 40 Staf Obligations 43 Appendix 3 : Guidelines for PBL 48 Appendix 4 : Organizational Structure 50 Appendix 5 : Evaluation of study results 51 Appendix 6 : Module Flowchart 53 Appendix 7 : Evaluation Sheets 54

Instructional Design Book, Immunology and Infection Module, FMUI 2012

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PREFACE In an effort to improve the quality of education in the Faculty of Medicine University of Indonesia to reach the regional/international standard, a new curriculum was made based on the Problem-based Learning method, which will be integrated and mainly executed into modules Infection and immunology module is the 11th module, administered in 6 weeks in 6th semester. The final goal of infection and immunology module is to reach stage 1 competence of the FMUI 2005 medical curriculum which consists of 6 major competencies and 3 minor competencies. This instructional design book is a guidance for the resource persons, the organizing committee, tutors and students; it contains all information related to infection and the human immune response which will provide the medical students ready for the clinical stage. Through this module, students are expected to learn anatomy, physiology, regulation of the immune system in normal and pathology especially in relation to infection. The scope of infection covers the pathogen and its interaction with the host immune system, innate and adaptive immunity, main clinical manifestations and the management. We thank everyone that has helped in developing this book, especially the Infection and immunology Module development team. We sincerely hope this book will of benefit for all of us.

Jakarta, January 2012

Organizing Committee

Instructional Design Book, Immunology and Infection Module, FMUI 2012

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CHAPTER I INTRODUCTION

1. Module name: Infection and Immunology Module

2. Module code: SI

3. The module is administered in semester VI as a parallel activity in two classes i.e. regular and international classes.

4. Total credits: 5

Immunology and infection module is a series of learnings which are intended to encourage students to learn and understand all aspects of basic immunology and infectious disease. This module covers normal regulatory immune response up to pathology in infectious disease. Immune response is basically important events in human which regulate the body’s immune system against foreign antigens including infections. Infectious diseases are still the primary cause of morbidity in Indonesia and developing countries in the tropics. Some problems that correlate with infectious diseases in last two decades are HIV, bioterrorism, malaria, tuberculosis, infective diarrhea, and avian influenza. Apart from its role in infection, immune response also has contribution in autoimmune disease, transplantation, diagnostic kit construction, production of vaccines and immunotherapy. Infection and immunology module is the 11th module, administered in 6 weeks in 6th semester. Through this module, students are expected to learn anatomy, physiology, regulation of the immune system in normal and pathology especially in relation to infection. The scope of infection covers the pathogen and its interaction with the host immune system, innate and adaptive immunity, main clinical manifestations and the management

Instructional Design Book, Immunology and Infection Module, FMUI 2012

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STUDENTS CHARACTERISTIC Students qualified to attend Immunology and Infection module are: Stage III students who have passed stage I and stage II curriculum; therefore they have achieved various learning skills. Students have been mastering basic skill and basic behaviour i.e. life-long study, general skill and empathy toward environment and community.

Instructional Design Book, Immunology and Infection Module, FMUI 2012

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CHAPTER II

LEARNING OBJECTIVES

Terminal Learning Objectives After completion of this module, the students are expected to acquire basic knowledge, clinical and laboratory skills in immunology and infection, have capability to implement standard problem solving steps in basic management of patients with immune disorders and infectious diseases, able to use the technology to seek information and related references, research in infectious diseases, capability in self development, manuscript writing and develop appropriate attitude and personality necessary to support their profession such as life long learning skill, integrity, sense of responsibility, credibility, respect patients as human beings in accordance to medical ethics.

Supported Learning Objectives

I. When provided with secondary data about clinical, laboratory and epidemiology problems of immune disorders and infectious diseases, students are able to:

1. Identify the problems by integrating biomedical and clinical science. 2. Explain in normal structure and function of organs involved 3. Explain the pathogenesis and pathophysiology of the disorders 4. Analyse the etiology, determine diagnosis and differential diagnosis 5. Plan the management and prevention 6. Explain the prognosis and its influencing factors 7. Explain the complications and their management 8. Explain medical emergencies in immunology and infection diseases, and their management

II. When provided with a simulation patient, students are able to:

1. Collect appropriate data history on the problems given 2. Do the routine physical examination ing to the problems 3. Determine necessary supporting examinations 4. Interpret the results of supporting examinations 5. Make diagnosis and differential diagnosis 6. Plan comprehensive management (including prevention, rehabilitation and referral) 7. Communicate to the patient with empathy both in verbal and non verbal and act as active

listener

III. When provided with data of immune disorders/infection problems in a community, students are able to:

1. Determine the extent of the problem in the community 2. Determine the etiology factor or other factors related to development of the problems 3. Set up plans to solve the problem (prevention, treatment, rehabilitation) in the community. 4. Explain the management of the problem

IV. Able to stimulate basic and applied research topics in infectious diseases and immune disorders

Instructional Design Book, Immunology and Infection Module, FMUI 2012

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CHAPTER III

TOPIC DISCUSSION

Materials Subjects Topics References Basic Immunology

1. Components of

Immune System

- Antigen and immunogen - Cell and organ of immune system - Immunoglobulin, complement,

cytokines - Major Histocompatibility Complex

(Classification, structure, function) - Molecule and surface receptors

1, 2, 4

2. Immune Responses

- Non specific / innate / natural immune response: humoral and cellular

- Specific immune response: humoral and cellular.

1, 2, 4

Immuno- Pathology

1. Hipersensitivity Hipersensitivity reaction - Type and mechanism Hipersensitivity diseases - Classification (immune response type

and effector mechanism) - Pathogenesis of disease - Supportive laboratory examination - Management (pharmacologic and non

pharmacologic)

1, 2, 4, 9, 10, 11, 12

2. Immunodeficiency Congenital Immune deficiency T Cell Deficiency - Disease and pathogenesis - Screening & follow up laboratory

examinations and its interpretation B Cell Deficiency - Disease and pathogenesis - Screening & follow up laboratory

examinations and its interpretation Non Specific immune deficiency - Disease and pathogenesis - Screening & follow up laboratory

examinations and its interpretation Acquired Immune deficiency - Aetiology - Disease and pathogenesis - Screening & follow up laboratory

examinations and its interpretation - Immunonutrition - Management (pharmacologic and non

pharmacologic)

1, 2, 4, 9, 10, 11, 12, 16

Instructional Design Book, Immunology and Infection Module, FMUI 2012

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3. Autoimmune Immune Tollerance - T cell tolerance (central and perifer) - B cell tolerance (central and perifer) - Tolerance to foreign antigens Autoimmune disease - Classification (organ and non organ) - Pathogenesis of autoimmune disease - Autoantibody (organ specific and non

organ) - Screening & follow up laboratory

examinations and its interpretation - Management (pharmacologic and non

pharmacologic)

1, 2, 4, 12

Immuno- diagnosis

1. Cellular immunity diagnostic tests

Non Specific - Quantitative test (neutrophyl count) - Phagocyte qualitative test

(Nitrobluetetrazolium, killing of microbes)

Specific - Lymphocyte quantitative test (T

lymphocyte, B lymphocyte, T helper and suppressor count)

- B lymphocyte quantitative test ( B lymphocyte count)

- Lymphocyte qualitative test (lymphocyte transformation, citotoxicity, migration inhibition, leucotaxis)

- Antigen recall (Mantoux test, Prick test)

2. Humoral Immunity diagnostic Tests

Non specific - Complement quantitative test (C3 and

C4 level determination) - Complement activity qualitative test Specific - Antibody quantitative test ( IgG, IgA, IgM, IgE level)

Immuno- therapy

Immunization - basic of immunization, immunomodulation

- various immune responses due to selective induction

- Kind of immunization - Application of immunization - Requirements for successful

vaccination

3, 7, 8

Basic of Infectious Disease

- General Feature of Infection - Immunology of infectious disease - Pathogenesis of infection and sepsis - Anatomy-histology- physiology of the regulation of body temperature

- Zoonosis

- Hypothalamus, skin, autonomous nervous system, (peripheral blood vessel, hemodynamic, mechanism of body defense)

- Immune response to infection (innate, acquired, specific, non specific)

- Transmission (vector and non vector)

6, 7, 8, 17, 18

Instructional Design Book, Immunology and Infection Module, FMUI 2012

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Bacterial infection - Classification of bacteria - Immune responses to bacterial

infection - Primary bacterial infectious disease

(typhoid fever, leptospirosis) - Immunopathogenesis of bacterial

infectious diseases - Clinical features - Screening & follow up laboratory

examinations and its interpretation - Management (pharmacologic and non

pharmacologic)

7, 8, 9

Parasitic Infection - Classification of parasite - Immune responses to parasitic

infection - Primary parasitic infectious disease

(malaria, filariasis) - Immunopathogenesis of parasitic

infectious disease - Clinical features - Screening & follow up laboratory

examinations and its interpretation - Management (pharmacologic and non

pharmacologic)

5, 6, 9

Viral Infection - Classification of Virus - Immune responses to viral infection - Primary viral infectious diseases

(Dengue, CMV, Chikungunya, avian influenza H5N1)

- Immunopathogenesis of viral infectious disease

- Clinical features - Screening & follow up laboratory

examinations and its interpretation - Management (pharmacologic and non

pharmacologic)

67, 8, 14

Systemic Fungal Infection

- Classification of fungi - Immune responses to fungal infection - Primary fungal infection disease

(Candida, PCP, Cryptococcus, Histoplasma)

- Immunopathogenesis of fungal infectious disease

- Clinical features - Screening & follow up laboratory

examinations and its interpretation - Management (pharmacologic and non

pharmacologic)

7, 8, 14

Nosocomial Infection and Sepsis

- Definition - Aetiology agents - Sources of infection - Lab diagnosis and resistency test - Management and prevention

7, 8, 17, 18

Laboratory Screening in Infectious Diseases

- Hematology - Serology (IgM, IgG, CRP, Calcitonin

etc)

4, 12

Instructional Design Book, Immunology and Infection Module, FMUI 2012

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Pharmaco-logy of Antimicrobes

Principles of the rationale drug use

- Mechanism of drug in infectious disease and immune system disorders

- Indication and contraindication - Drug dosage form, drug interaction - Side effect

13, 14, 15 Drug influencing the

immune system (immunomodulator)

- Immunosuppresive - Immunostimulant

Antiviral therapy - Nucleoside analogue reverse transcriptase inhibitors (NRTIs)

- Non nucleoside reverse transcriptase inhibitors (NNRTIs)

- Protease inhibitors (Pis) - Principles of antiretroviral drug

combination - Antiretroviral drug interaction

Additional Discussion Topics Module

Materials

Subjects

Topics

Research Research in infectious diseases and its correlation to immunology

- Research topic (serodiagnostic, patho- genesis, etc) - Research facility

Empathy and Patient Care (EPC)

Empathy and social culture communication, medical anthropology, and humaniora

Counselling to infectious disease patients (HIV, nosocomial infection, critical illness)

BCS Universal Precautions, Aseptic, Antiseptic, Wound hecting, Specimen collection, oropharingeal swab

Instructional Design Book, Immunology and Infection Module, FMUI 2012

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CHAPTER IV TEACHING METHODS

A. TEACHING METHODS

The teaching methods implemented in the immunology and infection module is an active learning consists of interactive lecture, group discussion, self discussion, supporting laboratory activity and basic clinical practice; using problem based learning approach. The teaching method in this module consists of three phases : 1. Orientation 2. Exercise 3. Feedback 1. Orientation The objective is to provide basic knowledge on immunology and infection in general.

a. Lecture - Lecture 29 hours

Basic general medical knowledge 3 hours Basic clinic medical knowledge 16 hours Clinic medical knowledge 9 hours

- Research discussion 2 hours - Empathy discussion 2 hours

b. PBL (Problem Based Learning)/Group discussion Group discussion for 4 triggers each 5 hours c. Laboratory activity Laboratory activity consists of: - Anatomy Pathology Lab Practice 2 hours - Clinical Pathology Lab Practice 2 hours - Parasitology Lab Practice 4 hours - Microbiology Lab Practice 4 hours - Practical examination 4 hours - Practical Pre-test by e-learning

2. Exercise The objective is to develop and increase student’s ability, skill and knowledge through:

a. Problem Based Learning b. Laboratory activities c. Daily Observation d. Presentation

3. Feedback

The objective is to give input to the students and the module organizer through evaluation of the learning process and the students’ scores. Feedback will be obtained through:

a. Plenary sessions b. Formative examination c. Summative examination d. Questionaires e. Laboratory activity report

Instructional Design Book, Immunology and Infection Module, FMUI 2012

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B. LEARNING SOURCES

- Textbook - Resource person - Handout - Laboratory activity/practical guide book - Internet

C. INSTRUCTIONAL MEDIA

- LCD - Flip chart - Microscope - Reagents & Laboratory equipments - Simulation tools - Notebook

Instructional Design Book, Immunology and Infection Module, FMUI 2012

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CHAPTER V ACTIVITY MATRIX

LIST OF LECTURERS

Day/Date Time Activity International Department

Week-1 Monday March 26, 2012

08.00-09.00

L1 Introduction

Arifin Nawas Module Team

09.00-10.00

L2 – Basic of Immunology

Dewi Wulandari

Clinical Pathology

10.00-11.00

L3- Hipersensitivity

Endang Rostini

Anatomy Pathology

11.00-12.00

L4-Clinical review of hypersensitivity reaction

Iris Rengganis

Internal Medicine

13.00-14.00

L5- Pharmacology of drugs used in hypersensitivity reaction

Rianto Setiabudy

Pharmacology

Wednesday March 28, 2012

08.00-09.00

L6- Basic principles & pathogenesis of bacteria & fungal infection

Budiman Bela Microbiology

09.00-10.00

L7- Basic principles and pathogenesis of viral infection

Budiman Bela

Microbiology

Thursday March 29, 2012

08.00-09.00

L8- Infection control and interpretation of microbiological examination results

Budiman Bela Microbiology

09.00-10.00

L9- Infection control and interpretation of microbiological examination results

Budiman Bela

Microbiology

10.00-11.00

L10- Pathogenesis of fever

Erni J. Nelwan Internal Medicine

11.00-12.00

L11- Clinical approaches of fever patient

Erni J Nelwan Internal Medicine

13.00-14.00 L12- Fever in Children

Alan R. Tumbelaka Paediatric

Friday March 30, 2012

10.00-11.00

L13- Immunomodulator and antipyretic

Rianto Setiabudy

Pharmacology

13.00-14.00

L14- Antimicrobials dosage forms and its application

Adisti Dwijayanti Pharmacy

Week-2

Tuesday April 3, 2012 08.00-09.00

L15- Basic principles of parasitology

Agnes Kurniawan Parasitology

09.00-10.00 L16- Immune response to parasitic infection

Agnes Kurniawan

Parasitology

Wednesday, April 4, 2012

08.00-09.00 L17-Epidemiology and Infection Setyawati B

Comm. Medicine

09.00-10.00

L18- Rational Antimicrobial Therapy (Pharmacology)

Rianto Setiabudy

Pharmacology

Week-3

Monday April 9, 2012

08.00-09.00 L19- Immunodeficiency

Endang Rostini

Anatomy Pathology

09.00-10.00 L20- Autoimmune

Instructional Design Book, Immunology and Infection Module, FMUI 2012

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Endang Rostini Anatomy Pathology

10.00-11.00

L21- Diagnostic tests for immunedeficiency and autoimmune

Dewi Wulandari

Clinical Pathology

11.00-12.00 L22- Pharmacology aspects of anti viral

Rianto Setiabudy

Pharmacology

13.00-14.00 L23- Clinical approach in immunodeficient and autoimmune patient (IPD)

Evy Yunihastuti

Internal Medicine

Wednesday April 11, 2012

08.00-10.00 General Lecture on basic concept of infection, immunology and clinical application. (IPD)

Djoko Widodo Internal Medicine

Friday April 13, 2012

10.00-11.00 L25-Opportunistic parasitic infection

Agnes Kurniawan

Parasitology

13.00-14.00 L26- Supporting Lab tests in Infection ( CP)

Ninik Sukartini

Clinical Pathology

Week-4

Wednesday April 18, 2012

08.00-09.00

L27- The role of nutrition in infection and Immune disorders (Dept. of Nutrition)

Fiastuti W Clinical Nutrition

09.00-10.00 L28- Basic Principles in immunization and Immuno- therapy (IKA)

Alan R. Tumbelaka. Paediatric

Instructional Design Book, Immunology and Infection Module, FMUI 2012

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Week I

Time Monday, 26 March 2012 Tuesday, 27 March 2012 Wed, 28 March 2011 Thurs, 29 March 2012 Friday, 30 March 2012

7:00 - 8:00 SDL SDL SDL SDL

GD2 – T1

8:00 - 9:00 L1- MODULE

INTRODUCTION (Team)

GD1 – TI

L6,7 - Basic principles and pathogenesis of bacterial, fungal, viral

infection (Micro)

L8,9 - Infection control and interpretation of

microbiological examination results

(Micro) 9:00 -10:00 L2 - Basic Immunology (CP)

10:00 - 11:00 L3 - Hipersensitivity

Reaction (AP)

BCS BCS

L10 - Pathogenesis of fever (IPD)

L13 - Imunomodulator and antipyretic (Pharmacology)

11:00 - 12:00 L4 - Clinical Review of

Hipersensitivity Reaction (IPD)

L11 – Clinical approaches of Fever

patient (IPD)

SDL

12:00 - 13:00 BREAK

13:00 - 14:00 L5 - Pharmacology of drugs

used in Hipersensitivity Reaction (Pharmacology)

BCS

BCS

L12 – Fever in Children (IKA)

L14 - Antimicrobials dosage forms and its application (Farmasi)

14:00 -15:00 SDL SDL SDL

Instructional Design Book, Immunology and Infection Module, FMUI 2012

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Week 2

Time Monday, 2April 2012 Tuesday, 3 April 2012 Wed, 4 April 2012 Thurs, 5 April 2012 Friday, 6 April 2012

7:00 - 8:00

PLENARY 1

SDL

L15- General Lecture on basic concept of

infection, immunology and clinical application.

(IPD)

GD 1 – T2

SDL SDL

HO

LID

AY

8:00 - 9:00

L15 - Basic principles and pathogenesis of

parasitic infection (Parasitology)

L17 - Epidemiology and Infection (IKK)

FORMATIVE 1 Feedback

9:00 - 10:00 L16- Immune response to parasites (Parasitology)

L18 - Rational Antimicrobial Therapy

(Pharmacology)

10:00-11:00 PAR W

Micro X

BCS

BCS

PAR Z

Micro Y

11:00-12:00

12:00-13:00 BREAK

13:00-14:00 PAR

Y

MICRO Z

BCS

BCS

PAR X

Micro W 14:00-15:00

Instructional Design Book, Immunology and Infection Module, FMUI 2012

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Week 3

Time Monday , 9 April 2012 Tuesday , 10 April 2012 Wed, 11 April 2012 Thurs, 12 April 2012 Friday, 13 April 2012

7:00 - 8:00

SDL

SDL

SDL SDL

GD2 – T2 8:00 - 9:00 L19 - Imunodefisiensi (AP)

GD1-T2

L24- General Lecture on basic concept of

infection, immunology, and clinical application

(IPD)

SUMATIVE 1

9:00 - 10:00 L20- Autoimmune (AP)

10:00-11:00 L21- Diagnostic tests for immunedeficiency and autoimmune (CP)

BCS

BCS

CP Z

PA Y

L25- Opportunistic parasitic infections

(Parasitology)

11:00-12:00 L22- Pharmacology aspects of anti viral (Pharmacology)

SDL

12:00-13:00 BREAK

13:00-14:00

L23- Clinical approach in immunodeficient and autoimmune patient

(IPD)

BCS BCS

CP X

PA W

L26- Supporting Lab tests in Infection ( CP)

14:00-15:00 SDL SDL

Instructional Design Book, Immunology and Infection Module, FMUI 2012

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Week 4

AP = Anatomy Pathology Micro = Microbiology SDL = Self Directed Learning

CP = Clinical Pathology Par = Parasitology BCS = Basic Clinical Skill IKA= Paediatric IPD = Internal Medicine Comm Med = Community Medicine

Time Monday , 16 April 2012 Tuesday, 17 April 2012 Wed,18 April 2012 Thurs,19 April 2012 Friday, 20 April

2012

7:00 - 8:00

PLENARY 2

SDL SDL SDL

GD2 – T3

8:00 - 9:00

GD1-T3

L27- The role of Nutrition in infecion and immune

disorder (Dept. of Nutrition) FORMATIVE 2

Feed Back

9:00 - 10:00 L28- Basic Principles in

immunization and Immunotherapy (IKA)

10:00-11:00 CP W

PA X

BCS

BCS

PAR Z

Micro Y

Research

11:00-12:00

12:00-13:00 BREAK BREAK

13:00-14:00

CP Y

PA Z

BCS

BCS

Par X

Micro W

Research

14:00-15:00

SDL

Instructional Design Book, Immunology and Infection Module, FMUI 2012

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Week 5

Time Monday, 23 April 2012 Tuesday, 24 April 2012 Wed, 25 April 2012 Thurs, 26 April 2012 Friday, 27April 2012

7:00 - 8:00

PLENARY 3

SDL SDL SDL

GD2-T4

8:00 - 9:00

GD1-T4 EPC

PRACT TEST (Par, Micro, CP, AP)

9:00 - 10:00

10:00-11:00

PAR Z

Micro Y

BCS

BCS

11:00-12:00

12:00-13:00 BREAK

13:00-14:00

Par X

Micro W

BCS

BCS

PRACT TEST (Par, Micro, CP, AP)

SDL

14:00-15:00

Instructional Design Book, Immunology and Infection Module, FMUI 2012

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Week 6

Time Monday, 30 April 2012 Tuesday, 1 Mei 2012 Wednesday, 2 Mei 2012 Thursday, 3 Mei 2012 Friday, 4 Mei 2012

7:00 - 8:00

PLENARY 4

SDL

SDL

SDL

SDL

8:00 - 9:00

SUMMATIVE 2

9:00 - 10:00

10:00-11:00

SDL SDL

11:00-12:00

12:00-13:00 BREAK

13:00-14:00

SDL SDL SDL SDL SDL

14:00-15:00

Instructional Design Book, Immunology and Infection Module, FMUI 2012

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CHAPTER VI HUMAN RESOURCES

Resource Persons No Name of lecturer Departement

1 Dr.dr.Iris Rengganis, SpPD-KAI Internal Medicine

2 Dr. Erni J. Nelwan Internal Medicine

3 Prof. Dr. Djoko Widodo, SpPD-KPTI Internal Medicine

4 Dr. Dewi Wulandari, SpPK, MSc Clinical Pathology

5 Dr. Ninik Sukartini, DMM, SpPK(K) Clinical Pathology

6 Prof. DR. Dr. Rianto Setiabudy, SpFK Pharmacology

7 Dr. Endang SR Hardjolukito, MS., SpPA(K) Anatomy Pathology

8 DR. Dr.Budiman Bela, SpMK Microbiology

9 Dr. Agnes Kurniawan, PhD, SpParK Parasitology

10 Dr. Fiastuti W.,MSc, MS, SpGK Clinical Nutrition

11 Dr. Alan R. Tumbelaka, SpA. Paediatric

12 Dr.Setyawati Budiningsih,MPH Community Medicine

13 Dr. Adisti Dwijayanti Pharmacy

Facilitators for group discussion

No Name Departement 1 Dra. Rahmawati Ridwan, Apt, MS

Chemistry

2 Dr. Primariadewi Rustamadji, MM. SpPA.

Anatomy Pathology

3 Dr.Astrid Sulistomo

Community Medicine

4 Dr. Ninik Sukartini DMM, SpPK (K) Clinical Pathology

5 Dr. Isnani A. Suryono, MS

Histology

6. Dr.Maria Fransisca Ham, PhD, SpPA

Clinical Pathology

– Practical Instructors 3 - 7 persons per practical session – Module Organizer 4 persons (Chair; Vice Chair; Secretary for reguler and international

class)

Instructional Design Book, Immunology and Infection Module, FMUI 2012 22

Resource Persons for Plennary Session Departement PLENNARY 1 Dr. Dewi Wulandari, SpPK, MSc Clinical Pathology Dr. Endang SR Hardjolukito, MS, SpPA(K) Anatomy Pathology Dr.dr. Evy Yunihastuti, SpPD-KAI (*) Internal Medicine Prof. DR.Dr. Rianto Setiabudy, SpFK Pharmacology PLENNARY 2 DR. Dr. Budiman Bela Microbiology DR. Agnes Kurniawan, PhD, SpParK Parasitology Dr. Ernie J. Nelwan, SpPD-KPTI Internal Medicine Dr. Ninik Sukartini, DMM, SpPK (K) Clinical pathology Prof.DR.Dr. Rianto Setiabudy, SpFK(*) Pharmacology PLENNARY 3 Dr. Endang SR Hardjolukito, MS, SpPA(K) (*) Anatomy Pathology

Dr. Ernie J. Nelwan, SpPD-KPTI Internal Medicine DR. Agnes Kurniawan, PhD, SpParK Parasitology Prof.DR.Dr. Rianto Setiabudy, SpFK Pharmacology DR. Dr. Budiman Bela Microbiology

PLENNARY 4 Dr.Setyawati Budiningsih,MPH Community Medicine dr. Alan R. Tumbelaka.SpA (*) Paediatric

Dr.dr.Iris Rengganis, SpPD-KAI Internal Medicine DR. Dr. Budiman Bela Microbiology

(*) : MODERATOR

List of Immunology and Infection Module Organizer

No Name Department Position

1. Dr. Dra. Taniawati Supali Parasitology Chairman

2. Dr. Kie Chen, SpPD Internal Medicine Vice chairman

3. Dr. Yulia Rosa S., SpMK Microbiology Secretary Reg

4. Dr. Lisawati Susanto, MS Parasitology Secretary Int

5. Prof. DR. Dr. Rianto Setiabudy, SpFK Pharmacology Member

6. Dr. Arifin Nawas SpP(K), MARS Pulmonology Member

7. Dr. Dalima Astrawinata, SpK Clinical Pathology Member

8. Dr. Dina Muktiarti, SpA Paediatric Member

9. Dra. Mulyati, MS Parasitology Member

10. Dr. Maria Fransisca Ham, PhD, SpPA Anatomy Pathology Member

Instructional Design Book, Immunology and Infection Module, FMUI 2012 23

FACILITY FACILITY

1. Facility

There are 60 students in international class, divided into 6 groups.

No Description International class

Quantity Unit

1. Instructional Guide Book (IGB)

15 Books

2. Tutor Guide Book (TGB)

60 Books

3. Student Guide Book (SGB)

20 Books

4. Reference (for each group) 6

Sets

5. Computer with connection to the internet for each group

6 Units

6. Lecture tools : - OHP - Slide projector - Multimedia projector - White board/Flip chart

1 1 1 4

Unit Unit unit

items

7. Microscopic slides histology-AP

20 Sets

8. Material and for Parasitology, Microbiology, and Clinical Pathology Practical Activity

3 Sets

2. Rooms

– Lecture room o 1 big lecture room with adequate facility for 60 students

– Discussion room for SDL: o 6 discussion rooms adequate for 8-12 students

– Practical laboratory room with capacity for 75 students o Microbiology o Parasitology

– Group discussion room for special topic: o 3 group discussion rooms adequate for 15-20 students

– Computer laboratory – Library

Instructional Design Book, Immunology and Infection Module, FMUI 2012 24

References : I. Textbook TITLE AUTHOR PUBLISHER YEAR/EDITION

IMMUNOLOGY

1. Cellular and Molecular Immunology

Abbas AK,Lichtman AH WB. Saunders, Philadelphia

2003/5th ed

2. Imunology & Serology in Laboratory Medicine,

Turgeon ML. Mosby, St.Louis 2003/3rd ed

3. The Immunology of vaccination, In: Vaccines.

Ade G, In: Plotkin SA, Mortimer (eds)

Philadelphia. WB. Saunders

1999/2nd ed. p.28-40

4. Imunologi Dasar Baratawidjaja, KG Balai Penerbit FKUI

2000/ ed 4

PARASITOLOGY

5. Principles & Practice of Clinical Parasitology

Gillespie SH, Pearson RD

John Willey and Sons.

2001

6. Foundations of Parasitology Roberts LS, Janovy J McGraw-Hill, Inc.

2005/7th ed

MICROBIOLOGY

7. Medical Microbiology Mims C, H.M. Dockrell, R.V. Goering et al

Mosby, Toronto 2008/ 4th ed

8. Manual of Cinical Microbiology Murray CR, Baron EJ, Jogersen JH et al

ASM Press 2007/9th ed

9. Benneth & Brachman Hospital Infections

Jarvis WR Lippincott Williams & Wilkins

2007/5th ed

ANATOMY PATHOLOGY

10. Pathologic Basis of Disease Cotran, R.S., V. Kumar, T. Collins

WB Saunders Co.

2004/7th ed

11. General And Systemic Pathology 12. Buku Ajar Patologi

JCE Underwood Himawan S

Churchill Livingstone Sagung Seto

2003/3rd ed 2002 / 1st ed

CLINICAL PATHOLOGY 13. Imunologi: Diagnosis dan Prosedur

Laboratorium

Kresno SB

Balai penerbit FKUI

1991, 2nd ed

PHARMACOLOGY 14. The Pharmacological Basis of Therapeutics

Brunton LL in Goodman & Gilman’s

McGraw-Hill, Inc

2006, 11th ed p.1679-1706

15. Antiiviral agents, In: Basic & Clinical Pharmacology

Katzung BG, Safrin S McGraw-Hill, Inc. NY

2004/ 9th ed p. 801-27

Instructional Design Book, Immunology and Infection Module, FMUI 2012 25

TITLE AUTHOR PUBLISHER YEAR/EDITION

16. Immunopharmacology, In: Basic and Clinical Pharmacology

Katzung BG , Lake DF, Adrienne DB, Akporiaye ET

McGraw-Hill, Inc. NY

2004/ 9th ed p. 931-57

NUTRITION 17. Imunonutrition

Shills ME, Olson JA, Moshe S, Cathar R

9th ed, p.305-47,p.1503-11

Internal Medicine 18. Harrison's Principles of Internal Medicine

Kasper DL, Braunwald E, Fauci AS et al

McGraw-Hill, Inc. NY

2005/16th ed

19. Buku Ajar Ilmu Penyakit Dalam

Setiati S, Sudoyo AW, Idrus Alwi, Simadibrata M, Setyohadi B

Pusat Informasi Ilmu Penyakit Dalam(PIP)

2007/ 4th ed

Instructional Design Book, Immunology and Infection Module, FMUI 2012 26

Chapter VII

EVALUATION

A. EVALUATION OF THE STUDENTS’ OUTCOME Evaluation will be taken in the form of observations of group discussion, laboratory activities, written examination, Lab practice examination, and student book assessment. Observation will be performed through a check list to assess student’s participation, argumentation, activity, interaction, attitude in communication and discussion. Written summative evaluation using MCQ will be done twice, in the middle of week 4 and week 6

Mode of assessment

Group Discussion : 25%

Log book 5 %

Lab. Practice report : 10%

Theory exam : 50%

Integrated Lab. practice exam:

10%

Before summative written test, there will be two formative written tests at week 2 & week 5. Formative evaluation will not be considered in the student score. Passing level of immunology and infection module is average score of 55 (C) based on each component above. B. EVALUATION OF EDUCATIONAL PROGRAM Module effectiveness: Students pass with minimum score of C > 90% Passing score : 55 Module efficiency:

- 90% of activities are conducted on time as scheduled - Attendance of students, facilitators, lecturers, plenary moderators and Lab. practice

supervisors > 90%. After the written test, students and facilitators are requred to fill in a questionnaire as a feedback to the module organizer.

Instructional Design Book, Immunology and Infection Module, FMUI 2012 27

Appendix 1

TRIGGERS

TRIGGER 1: A BOY WITH RECURRENT SNEEZING

Indra, 8 years old, came to the clinic with complaint of recurrent sneezing and cold, since a year ago.

These complaints were often accompanied by watery and itchy eyes. He often rubbed his itchy nose.

These complaints occurred mostly in the morning or when Indra played in a dusty place. Indra’s

mother, Mrs. Tuti, had frequent attacks of short breathing mostly at night. Indra’s sister aged 3 years

old, Asih, suffered frequent skin itching, especially when she consumed shrimp. His father and sister,

however, did not have any of these complaints.

TRIGGER 2: A MAN WITH FEVER

Dr. Bayu, 25 years old, is a physician who has completed his compulsory work (PTT) in East

Kalimantan 2 months ago and has returned to Jakarta. He was brought to a hospital due to high fever,

shivering, sweating, paleness, headache and vomiting. Previously he had the same symptoms in

Kalimantan. Physical examination: temperature 38.30C; pulse 100x/minute; blood pressure:

120/80mmHg; respiratory rate: 18X/minute.

TRIGGER 3: A 20 YRS OLD STUDENT WITH CHRONIC DIARRHEA

A student, 20 years old, came to the hospital because of diarrhea that has been experienced for

about 1 month. Everyday, the patient experienced diarrhea 4-5 times with a moderate amount and

liquid stool consistency. The patient has received treatment at the primary health care, but there was

no improvement. Since having the illness, the patient experienced weight loss of 7 kg. The patient

was an ex-injecting drug user. At the time of admission, the patient was weak, the temperature of

38.50 C, pulse 100x/minute, blood pressure 100/60 mmHg.

TRIGGER 4: A CHILD WITH SWOLLEN NECK

Neni, 6 years old, came to the emergency unit with chief complain of painful swellings on left and right

neck since three days ago. The patient also had high fever and sore throat. He has been vaccinated

with BCG, 3x Hepatitis B, 2x DPT, 2x Polio but he never had measles vaccination.

From physical examination, the child looked conscious, had no difficulty of breathing and no cyanosis.

Pulse rate was 10x/min, regular, with normal volume. Respiratory rate was 28X/min, regular. Axillary

temperature was 37.8°C. The size of tonsils was T2-T2, and there was grayish white membrane

spread over both tonsils until pharynx which was difficult to be detached and easy to bleed. The

lymphatic glands at left and right neck were enlarged with size 7x5x2 cm and had skin colour, were

warm and tenderness at palpation. Other physical examination were normal.

Yann
Yann

Instructional Design Book, Immunology and Infection Module, FMUI 2012 28

APPENDIX 2

DUTY AND RESONSIBILITY PERSON IN CHARGE OF MEDICAL EDUCATION MANAGER PROGRAM DIRECTOR, YEARLY COORDINATOR & MODULE DIRECTOR IN THE 2005 FACULTY CURRICULUM OF MEDICAL FACULTY UNIVERSITY OF INDONESIA

PERSON IN CHARGE OF MEDICAL EDUCATION ORGANIZER

1. Responsible to the Education Manager

2. Responsible in implementing the 2005 Faculty Curriculum of Medical Faculty University of Indonesia – Regular Class and International Class.

3. Responsible in evaluation of the overall 2005 Faculty Curriculum, in both regular and international classes (by giving feedback to MEU to organize the 2011 Faculty Curriculum)

4. Carry out Progress test, together with MEU.

II. PROGRAM DIRECTOR

Responsible to the Person in Charge of medical education organizer

Execute the 2005 Faculty Curriculum in both regular class and international class.

Organize evaluation meeting every semester, inviting:

a. Module director in the corresponding semester b. Yearly coordinator in the corresponding semester c. Person in charge of medical education organizer d. Education Manager e. MEU Director f. Vice Dean I g. Dean. Maintaining the course of yearly academic calender (module implementation, holiday,

examination, yudisium meeting and submitting the result of yudisiu) in accordance with University of Indonesia academic calender, taking into consideration:

a. program in accordance with the curriculum b. deadline for grade / graducates submittance to University of Indonesia

Organize internal evaluation instrument, especially program evaluation for each module and to report the result to the module organizer, yearly coordinator, person in charge of 2005 Faculty curriculum implementation, Education Manager, Vice Dean I, and Dean of Medical Faculty.

Accept module implementation report, including evaluation result from yearly coordinator.

Responsible in calculating student’s Grade Point Average (GPA) at the end of Bachelor in medical science education program, at the end of semester 8 and Medical Doctor at the end of semester 10.

Supervise the graduates data preparation by educational secretariat, after which will be submitted to the University of Indonesia Education Director in Depok, in coordination with assistant manager of education administration.

Instructional Design Book, Immunology and Infection Module, FMUI 2012 29

Convey report of problematic student in one year to the next yearly coordinator, for it to be given a special attention.

Give special attention to problematic student in every level during the implementation of 2005 Faculty Curriculum. In addition, to call upon those students and to report them to the team for evaluation of continual study via the Education Manager.

Receive report from assisstant manager of education administration in regard to student whose study term is almost over, to be further evaluated.

YEARLY COORDINATOR

1. Organize yearly activity calendar which includes modul implementation date, modul evaluation meeting, yudisium meeting and submitting result of yudisium, in accordance with the UI academic calendar. This activity calendar is assembled together with module organizer, regular and international class program directors.

2. Supervise the implementation of module activity:

a. Receive and evaluate module director’s report b. Carry out evaluation module implementation at the end of each module.

3. Report module implementation, including result of student evaluation to the Program Director of Medical Education for Regular class/ International class and Medical Education Organizer during yudisium meeting for regular / international class.

4. Receive module final grade **) after REVISION-1 from Module Director (pre-yudisium)

5. Organize yudisium meeting at the end of every even semester (end of academic year), of which the date is decided together with Vice Dean I/ Education Manager/ Program Director for Regular class and International class, inviting:

a. Program Director for Regular class/ International class

b. Medical Doctor Education Organizer

c. Education Manager

d. MEU Director

e. “Mahalum” Manager

f. Vice Dean I

g. Dean

h. UPMA

i. Evaluation team for continual study

j. Counseling team Medical Faculty UI

6. Responsible in filling in student final score (including those directly passed or with remedial) into the yudisium form and student academic card, at the end of even semester.

7. Give back the yudisium form to the student.

8. Receive report and manage further students whom failed the remedial exam and report it to the MEU Evaluation Committee.

9. Follow up the Evaluation Committee recommendation as follows:

a. Students who are still eligible to continue their study, will be submitted their names to the secretariate education program for regular class/ international class, who will then further included into the next modul acitivity.

b. Students who are not eligible to continue their study, will be reported to the Education Manager and evaluation team for continual study

10. Receive and follow up the recommendation of evaluation team for continual study, as follows:

Instructional Design Book, Immunology and Infection Module, FMUI 2012 30

a. Students who are still given a chance to continue their study, will be submitted their names to the secretariate education program for regular class/ international class, and will be included to next module activity which they have to repeat.

b. Students who cannot continue further their study, will be reported to the Education Manager to given a letter of study discontinuation.

11. Confirm the fulfilment of student requirements for each modul participants, before their names submitted to the next subprogram.

12. Supervise the distribution of students groups in module which are carried out in rotation.

MODULE DIRECTOR

1. Complete the Guide Book: Instructional Design, Tutor Guide Book, Student Guide Book in coordination with Medical Education Unit (MEU).

2. Assemble module activity matrix in accordance with the time of modul implementation which have been decided with yearly coordinator and undergraduate program director for regular class and international class.

3. Carry out module activity in accordance to the Guide Book.

4. Report to the Yearly Coordinator, concerning:

a. module implementation

b. result of study evaluation

c. problematic students who need special attention.

MODULE VICE DIRECTOR

Carry out evaluation of study program Report the result of evaluation to module director.

Instructional Design Book, Immunology and Infection Module, FMUI 2012 31

STAFF OBLIGATIONS 1. THE OBLIGATION OF MODULE COORDINATOR TEAM The module coordinator team consists of: Module Director Module Vice Director Module Secretary Secretariat staff: 3 persons (in accordance with HRD provision) PRE- MODULE OPERATION

1. Reevaluate the matrix activity adjusted to: a. national holiday b. availability of facilities such as laboratory class/skills lab, etc c. time readiness of resource person who is responsible for lectures d. accessibility of educational infrastructure in Leading Center Development Hospital:

Rumah Sakit Umum Pusat Persahabatan (RSP), Rumah Sakit Penyakit Infeksi Prof. Dr. Sulianti Saroso, Jakarta (RSPI-SS), RSAB Harapan Kita and Pusat Jantung Nasional Harapan Kita

2. Submit application letter of module realization budget to the Manager of Finance based on budget agreed by Director of UCP / MEU (acquainted by Director of MEU) belatedly 1 month before the module begins.

3. Receive following data from Sub-Program Coordinator a. student name and group list (source: Coordinator of Education Program of Regular

Class & International Class) b. evaluation form for group discussion by tutor (source: MEU) c. facilitator name list (source: HRD Manager co Responsible Coordinator of Doctor

Education Program) 4. Arrange the obligation schedule for teaching staff

a. Resource person: lecture, plenary session, summary session b. Facilitator: group discussion and examination bystander

5. Organize the preparation meeting a. involving resource persons about:

i. Lecture: time and material readiness, including continuity among lectures material (provided that there is any continuity)

ii. Plenary and Feedback session: time readiness of 3-4 resource persons and follow up after post-plenary feedback session.

iii. Readiness of teaching material to be comprised in virtual class, (teaching material in the form of LECTURE OUTLINE/ HANDOUT given to MEU Secretariat and will be uploaded by Labkom staff: Mr. Wahyono / Mr. Syafei)

iv. Outline of examination material and activity schedule of examination document creation

b. involving facilitator about: i. Explanation of module objective i. Important aim about materials for group discussion, such as: triggers and pointers/

keywords/question and answer list ii. Evaluation of facilitator duty and operating procedures iii. Assurance of time readiness and mechanism of facilitator substitution in module

operation iv. Explanation about group distribution and discussion room v. Facilitator’s on duty obligation (should the facilitators go directly to discussion room

or should they go to the secretariat first in order to obtain facilitator kit; should the attendance list be filled or should it be distributed with sudden inspection.

vi. Willingness of the facilitator to be a bystander of written examination vii. Explanation about payment for facilitators

6. Distribute the Student Guide Book which has been prepared by UCP/MEU to the student / student representative

7. Arrange copies of compulsory reference in accordance with the amount of student group and distribute them to the student/student representative

Instructional Design Book, Immunology and Infection Module, FMUI 2012 32

MODULE OPERATION

1. Prepare the activity class and equipment as follow: a. Lecture/Plenary Session/Feedback session: lecture class + AVA + 3 set of extra-

wireless microphone for students b. Discussion session: discussion room in accordance with student group amount +

flipchart + paper + board marker Note: The activity of laboratory practice is prepared by executive department of laboratory practice and Basic Clinical Skill (BCS) is prepared by BCS module

2. Monitor module activity operation / realization Note:

- The activity of laboratory practice is prepared by executive department of laboratory practice and coordinator of the department staff concerned – in coordination with module coordinator

- Basic Clinical Skill (BCS) is prepared by BCS module 3. Monitor student attendance as well as the problem and report it to Academic Counselor (AC) 4. Manage weekly evaluation meeting of module coordinator, resource persons, facilitators and

instructors. 5. Organize evaluation of study result

a. Preparation Examination schedule and location: time, examination room, distribution of student and

examination bystander based on examination room. Evaluation and supporting materials: examination documents, answer sheet,

examination rules, student attendance list, examination by stander, official report of examination accomplishment

b. Realization Carry out the examination punctually Check the examination result (written examination MCQ: examination result is checked

and analyzed at the MEU) c. Follow-up

Calculate student grade by the method in accordance with MEU guide Examine the result of examination question analysis and discuss it with resource

persons. note: Module coordinator in coordination with Director of Regular Class Program / International Class Program should prepare the examination room. As necessary, there should be coordination with General and Facilities Manager

6. Support realization of evaluation program executed by MEU through distributing and collecting questionnaire of evaluation program to the student / staff

POST- MODULE OPERATION

1. Arrange the module report consisting : a. ACTIVITY REPORT

i. Description about the activity program and its realization. ii. The involved teaching staff and students; recapitulation of student and staff

attendance list in each activity. iii. Special consideration:

1. Evaluation of facilitator’s attendance in discussion 2. Evaluation of lecture resource person’s attendance 3. Evaluation of resource person’s attendance in plenary and feedback

session. 4. Evaluation of infrastructure and equipment

iv. An evaluation report consists of: 1. The type of evaluation

Instructional Design Book, Immunology and Infection Module, FMUI 2012 33

2. The module grade list for every student 1 v. Closure: conclusion and suggestion

The report of module operation is submitted to the involved Sub Program Director in 2 weeks after module completed with the exception of the last module in even semester, which should be submitted in 1 week period.

b. FINANCIAL REPORT The written financial report (with enclosed receipt) should be completed together with the Financial Manager. Report copy should be handed to Responsible Coordinator of Doctor Education Program in Faculty of Medicine, University of Indonesia.

2. Arrange presentation of module report in module evaluation meeting, which is organized by Sub Program Director.

3. Submit final module grade2 post REMEDIAL-1 to Sub Program Director belatedly 2 (two) days before the 1st commencement meeting. The module grade is letter grade form in accordance with conversion grade based on Revised Faculty Curriculum, March 2006 (FMUI 1st Vice Dean Letter number 1791/PT02.M1 FK/Q/2006).

4. Participate in commencement meeting organized by Sub Program Director and verify the module grade in Sub Program recapitulation result.

5. Carry out the REMEDIAL-2 test in accordance with schedule determined by the Sub Program Director

6. Submit the final module grade of post REMEDIAL-2 to the Sub Program Director belatedly 2 (two) days before the 2nd commencement.

1 The module grade is submitted in print out and softcopy forms.

Instructional Design Book, Immunology and Infection Module, FMUI 2012 34

2. THE OBLIGATION OF FACILITATOR, RESOURCE PERSON AND MODERATOR FACILITATOR A. Group Discussion

a. Group Discussion 1 Introductory Session

Note: Facilitator should bring the Instructor Guide Book in every discussion especially in the first discussion.

Arrange student’s seat to ascertain well-discussion session, i.e. every participant may retain eye-contact with every member in discussion group

Introduce their self

Host the acquaintanceship session of group discussion member and evaluate the attendance list

Provide general explanation about process and objective of PBL as well as the evaluation process executed by the facilitator

Ask the group to select their leader and secretary of group discussion

Explain the duty of leader and secretary in discussion series Discussion of Trigger Problems Session

Invite the group leader to guide discussion, and it starts by reading the trigger problem. (Trigger reading may be done by every member or being read by one of discussion member. Reading the trigger loudly will keep the group member to be focused and recognizing pronunciation error of some terms, which should be corrected)

Keep a good group discussion in appropriate to PBL steps (Branda) The 1st – 6th PBL steps of Branda, i.e.:

1. Clarification of difficult term and definition of the problem 2. Analysis of the problem 3. Development of hypothesis (ses)/plausible explanation 4. Identification and characterization of the knowledge needed 5. Identification of what is already known 6. Identification of appropriate learning resources

Motivate or invite a more living discussion by giving statement such as “You have to make more questions” or “You have to find more information about it”.

End Session

Before the 1st discussion session ends, every participant should clarify their self-learning study program within two sessions by: o FIRST, participant should identify all issues o SECOND, allocate issue for every participant and determine the person who is

responsible for each issue. Basic problem should be read by all participants. o THIRD, determine SPECIFIC question which will be answered personally. o FOURTH, determine how participants could find / answer the learning issues

(example: by looking for information in their lecture note, reading text book, literature searching or by consultation with the resource person)

Fill up the evaluation form of group discussion process and group discussion result form 1.

Remind about the next meeting / group discussion schedule and remind that participant should take advantage in various study session (self-learning, lecture, laboratory practice, skill lab, etc) as a media in order to get new information / knowledge in the Self-Learning activity.

b. Group Discussion 2

Introductory Session

Begin the discussion session by reminding about end points in discussion 1

Take time for filling the attendance list Discussion Session

Instructional Design Book, Immunology and Infection Module, FMUI 2012 35

Direct the discussion process by implementing the 8th – 12th PBL steps of Branda, i.e.: 8. Synthesis of old and new information 9. Repetition of all or some of the previous steps as necessary 10. Identification of what was not learned 11. Summary of what was learned and if possible, 12. Testing the understanding of the knowledge by its application to another problem

Keep a harmonic discussion and be fair to all participants by asking students to: Have mutual participation to share and exchange knowledge (sharing and

pooling) for synthesizing it as a solving problem answer for the identified problem.

Understand that in discussion 2, the obtained knowledge should appropriate to questions collected in Discussion 1, and the answer should be based on available reference or other reference literature.

Record any new questions that occur in this discussion Report question and answer collected in Discussion 1 including the reference

to module responsible person

To perform their duty, facilitators should avoid giving direct answers to students. They facilitate students to stimulate thinking process, such as by giving another question to the student

Fill up the evaluation form of student group discussion process and result form of Discussion 2, and subsequently submit it to module responsible person after group discussion has been completed. (Explanation: there are two copies for evaluation form of discussion process and discussion result form. First copy is given to module responsible person and the second copy is given to student).

B. Others

Fill up the facilitator’s attendance list

Watch the examination determined by module responsible person

Participate in meetings hold by coordinator for module preparation and evaluation. RESOURCE PERSON

Prepare lecture materials and submit the softcopy to module responsible person.

Upload lecture materials to virtual class at www.kampus.fk.ui.ac.id Provide lectures in accordance with lecture schedule

Construct question for examination and submit it to the responsible person

Participate in meetings hold by coordinator for module preparation and evaluation

Should attend the plenary session, provide feedback and summary in accordance with schedule and determine the moderator on duty for that time

Check the written examination when computerized check is not available

As examiner for skill test LABORATORY INSTRUCTOR

Ask for module schedule to module responsible person

Prepare the necessary equipment and infrastructure for laboratory activity and assisted by laboratory staff

Provide supervision and training for student in accordance with the objective of laboratory practice

Fill up the evaluation form for student laboratory activity and submit it to module responsible person directly after the activity completed. (Explanation: there are two copies for evaluation form of student laboratory activity. First copy is given to module responsible person and the second copy is given to student.

Instructional Design Book, Immunology and Infection Module, FMUI 2012 36

APPENDIX 3

PROBLEM BASED LEARNING :

GUIDELINES FOR IMPLEMENTATION

A. PHILOSOPHY To become a scientist, students are required to use knowledge in explaining the occurrence of a problem and its management. Accordingly, in the student learning process, the acquired knowledge needs to be trained together with analytic thinking skills which are required to identify and manage problem in accordance to scientific methods of certain discipline. A medical doctor is always involved in managing medical problem of patient or people. Therefore, implementing scientific problem management steps is required to be mastered, in addition to nurturing the awareness attitude towards environment. Learning methods using problem based learning is aimed to enriched the learning process with connecting what student already know with new knowledge, which shows a continuation of knowledge studied. This learning process can always be used even though one has graduated from his medical education, because as a medical doctor, one will always face problems and do all steps to solve the problem using basic medical knowledge. Enriched learning is achieved when student can elaborate all the knowledge he mastered. B. PBL STEPS

1. Identification of problems in the trigger. Clarify all the unknown terms 2. Problem analysis with elaborating all the possible causes. 3. Assemble questions which correlate with each cause which still needs explanation, and then

form a hypothesis 4. Application of knowledge needed to answer each question. 5. Answer question which can be answered with the current acquired knowledge. 6. For those still unanswered questions, identify the necessary correlated resources. 7. Independent study. Result of this independent study is recorded in a book. 8. Assemble new knowledge based on what has been studied (old and new knowledge) 9. PBL steps can be repeated as needed 10. Identification of what cannot be studied. 11. Summarized all which have been studied. 12. If possible, test the new understanding of knowledge to other problems.

C. STUDENT’S GUIDELINE Based on the PBL steps in B, group discussion is divided into group discussion 1 (GD-1) to implement steps 1 – 7, and group discussion 2 (GD-2) to implement steps 8 – 12.

Guidelines for group discussion - 1 (GD-1)

1. For each group discussion, elect a chairman and secretary in rotation.

2. Read carefully each trigger. Each student reads by themselves.

3. Identify all the problems in the trigger.

4. Make a problem analysis, i.e. a possible correlations among all the issues, if exists, or a possible underlying mechanism for all identified problems in (3). Then make a hypothesis based on the problem analysis.

Instructional Design Book, Immunology and Infection Module, FMUI 2012 37

5. Assemble questions which correlate with all the possible connections between those issues or the underlying mechanism, which you do not know.

6. List those questions systematically according to key questions: what, why, how, etc.

7. Decide what knowledge is necessary to answer each question.

8. Select questions which you can answer with the knowledge you have now.

9. For those unanswered questions, plan to look for the answer on your own. If independent study is divided into groups, then each question should be answered by at least 2-3 students.

10. You have to record all the discussion from problem analysis (step 3) up to independent study (step 7)

Independent study (IS)

Independent study is a student learning activity done independently after each group discussion. Result of this study is recorded in your book, including all the references used written in order.

Guidelines for group discussion - 2 (GD-2)

1. Elect a chairman and secretary group discussion.

2. Each student gives report of his independent study with stating the reference. Other student pay attention and write down any necessary information to be discussed.

3. After every student gives their reports, a group discussion is started. In the discussion, correlate all the discussion with the questions.

4. Use all the answers you get to explain the problems identified in the trigger.

5. After all the discussion is finished, all students compile summaries of all independent study results and write them in their book.

Instructional Design Book, Immunology and Infection Module, FMUI 2012 38

APPENDIX 4

STRUKTUR ORGANISASI PENGELOLAAN PENDIDIKAN DOKTER FKUI SK Dekan No. 230/SK/D/FKUI/2005

Manajer Pendidikan

Penanggungjawab Pendidikan Dokter FKUI

Ketua Program Ketua Program Sekretariat Kelas Reguler Kelas Khusus Sekretariat

Sub Program Sub Program Sub Program Sub Program Sub Program Sub Program Pendidikan Umum Ilmu Kedokteran Praktik Klinik & General Medical Integrated Clinical Practice & Kedokteran Terintegrasi Kedokteran Komunitas Education Medical Sciences Community Medicine

Modul Modul Modul

Instructional Design Book, Immunology and Infection Module, FMUI 2012 39

APPENDIX 5

EVALUATION OF STUDY RESULTS 2006 FACULTY CURRICULUM

MANAGEMENT OF MODULE EXAMINATION Module evaluation is assess from 2 aspects: 1. Cognitive and practice with weight of 50% 2. Process and attitude with weight of 50% Follow up in module If a student failed, there will be a remedial examination given during module break. Module final grade after remedial is maximum of C, and this is the grade which will be brought to yudisium meeting. There will be no grade adjustment during yudisium meeting and there will be no remedial after yudisium. Follow up even semester yudisium 1. Pass 2. Repeat module 3. DO PREDICATE

GPA LEVEL YUDISIUM BACHELOR OF MEDICAL SCIENCE YUDISIUM

2.00 – 2.75 satisfactory satisfactory

2.76 – 3.50 Very satisfactory Very satisfactory

3.51 – 4.00 With honor cum laude

GPA PROFESSION YUDISIUM

2.50 – 3.00 satisfactory

3.01 – 3.50 Very satisfactory

3.51 – 4.00 cum laude

Note:

1. Module passing grade : final score ≥ 60 (C) for each module 2. Repeat module : if module grade is less than C

a. Student is presented to MEU Evaluation Committee, after failing a module. b. The failed module must be repeated at first chance according to the 2005 Faculty

curriculum schedule. c. Student can move on to the next module on the next semester d. The time for repeating module in one academic year is decided by the Subprogram

Director. e. If grade after repeating module is less than 60 (C), the student will be sent to MEU

Evaluation Committee for further evaluation.

Instructional Design Book, Immunology and Infection Module, FMUI 2012 40

3. DO (in accordance to UI academic rule SK no 478/SK/R/UI/2004) a. If on evaluation of the first 2 (two) semester, the GPA is less than 2,0 from minimum of

24 best credits. b. If on evaluation of the first 4 (four) semester, the GPA is less than 2,0 from minimum of

48 best credits. c. If on evaluation of the first 8 (eight) semester, the GPA is less than 2,0 from minimum

of 96 best credits. d. If on evaluation of end study period, GPA does not reach the minimum with grades of

all the required studies minimum of C. e. If study period cannot be finished within ”1 ½ n”

GUIDELINE FOR DETERMINING MODULE GRADE SUB PROGRAM INTEGRATED MEDICAL SCIENCES 2005 FACULTY CURRICULUM MEDICAL FACULTY UNIVERSITY OF INDONESIA

1. Summative evaluation is done at the end of each module with % weighing as follows: a. 50% knowledge-based assessment which can be acquired from (can be choosen and

determine its own % weighing) i. MCQ exam ii. MEQ exam iii. Essay exam iv. PSSS exam v. Practice exam

b. 50% process assessment which can be acquired from (can be choosen and determine its own % weighing)

i. group discussion observation (MEU format) ii. student note book (format MEU) iii. peer assessment

2. Formative evaluation is done twice for each module at during 2nd week and 4th week which

includes the same scope of assessment with summative evaluation (1a and 1b). 3. Progress test will be done twice a year, as a formative on 3rd and 4th semesters. At the end of

6th semester there will be a comprehensive examination as a summative before going to semester 7. Progress test is carried out by the person in charge of medical education organizer 2005 faculty curriculum.

Instructional Design Book, Immunology and Infection Module, FMUI 2012 41

APPENDIX 6 FLOWCHART OF EVALUATION OF THE STUDY RESULT KURFAK 2005

NEXT MODULE …

J U D I C I U

M

PASS (MODULE

GRADE 60)

REPEATING MODULE

(ARRANGED BY SUB PROGRAM DIRECTOR)

DROP OUT (DO)

SK REKTOR 478/SK/R/UI/200

4

MODULE GRADE

50%

COGNITIVE

50% PROCESS ATTITUDE

FINAL GRADE AFTER REMEDIAL IN THE MODULE

MODULE GRADE

50% COGNITIVE

50%PROCESS ATTITUDE

FINAL GRADE AFTER REMEDIAL IN THE MODULE

MODULE GRADE

50%

COGNITIVE

50% PROCESS ATTITUDE

FINAL GRADE AFTER REMEDIAL IN THE MODULE

MODULE GRADE

50%

COGNITIVE

50% PROCESS ATTITUDE

FINAL GRADE AFTER REMEDIAL IN THE MODULE

FAIL EVALUATION COMITTEE

Instructional Design Book, Immunology and Infection Module, FMUI 2012

42

APPENDIX 7

Faculty of Medicine University of Indonesia GENERAL MEDICAL EDUCATION SUBPROGRAM

INTEGRATED MEDICAL SCIENCES SUBPROGRAM

DISCUSSION REPORT – 1 Group : .......................... Facilitator name : .......................... Day/Date : ..........................

Module : .......................... Semester : .......................... Time : ..........................

Group members: 1. ............................................. 6. ............................................. 2. ............................................. 7. ............................................. 3. ............................................. 8. ............................................. 4. ............................................. 9. ............................................. 5. ............................................. 10. ...........................................

Problem Identification

Learning issues:

Data’s already collected

Issues that need to be learned

Facilitator Signature

(This form is signed by the facilitator after he verifies the content in accordance with the task given. After being signed, the form must be returned to the students)

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Faculty of Medicine University of Indonesia GENERAL MEDICAL EDUCATION SUBPROGRAM

INTEGRATED MEDICAL SCIENCES SUBPROGRAM

DISCUSSION REPORT– 2 Group : .......................... Facilitator name : .......................... Day/Date : ..........................

Module : .......................... Semester : .......................... Time : ..........................

Group members: 1. ............................................. 6. ............................................. 2. ............................................. 7. ............................................. 3. ............................................. 8. ............................................. 4. ............................................. 9. ............................................. 5. ............................................. 10. ...........................................

Group member participation in every member’s presentation

Presentation topic that still not clear

Solution :

Topic/question that hasn’t been discussed or answered:

Solution:

Facilitator signature

(This form is signed by the facilitator after he verifies the content in accordance with the task given. After being signed, the form must be returned to the students)

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MEDICAL EDUCATION UNIT FACULTY OF MEDICINE UI

MEMBER EVALUATION SHEET IN A GROUP DISCUSSION

(TO BE SUBMITTED TO THE MODULE ORGANIZER) Group : ______________ Module : ______________

Facilitator Name : ______________ Academic year : ______ – ______ Trigger : ______________

No Name Involvement Behavior Sum (Max: 40)

Sh

arin

g

Arg

um

en

tatio

n

Activ

ity

Do

min

an

t

Dis

cip

line

/Atte

nda

nce

Co

mm

un

ica

tion

1

2

3

4

5

6

7

8

9

10

11

Note:

Score Score

0-5 6-7 8-10 -5 -3 0

Sharing Minimum Sometimes Always Dominant Yes Sometimes No

Argumentation Poor Fair Good Discipline/ Attendance

Late > 15’

Late < 15’ On time

Activity Poor Fair Good

Communication poor Fair Good

Definition on evaluation term:

Sharing : sharing opinion/information related to the topic discussed between group member

Argumentation : giving logical knowledge and argumentation based on literature

Activity : active in discussion without facilitator intervention Dominant : dominating the forum in a group discussion Communication : listening, explaining and asking questions using

appropriate language systematically

Jakarta, ____,____________2009

(________________) ( _____ ______) facilitator I name facilitator II name

Instructional Design Book, Immunology and Infection Module, FMUI 2012 45

UNIT PENDIDIKAN KEDOKTERAN (MEDICAL EDUCATION UNIT) FKUI

FACILITATOR EVALUATION IN GROUP DISCUSSIONS

Facilitator Name : _____________________ (MUST be filled completely) Module :____________________________ Date:_______________ Student name : _________________________ (may be anonymously) Please evaluate your facilitator contribution in the process of group discussion. Please write comment on your facilitator specific habit. This feed back is very helpful for the facilitator and contribute to the effectiveness of your group discussion. This evaluation sheet should be put in the envelope, sealed and given to the facilitator or the secretary of module. Always Often Sometimes Never

I. ATTITUDES

1. Shows enthusiasm as a facilitator

2. Attend the discussion session as scheduled

3. Gives full attention and feed back on participants behaviour

II. SKILLS

4. Asking without directing, challenging questions

5. Avoiding mini-lecturing

6. Directing the student to a chosen source of information and learning materials

7. Helping the students focus on the learning issues and learning objectives

8. Give feedback and evaluate the process

9. Encourage critical thinking to see the whole topic in a comprehensive way

Comments:

Instructional Design Book, Immunology and Infection Module, FMUI 2012 46

FACULTY OF MEDICINE, UNIVERSITY OF INDONESIA SUBPROGRAM GENERAL EDUCATION SUBPROGRAM INTEGRATED MEDICAL SCIENCES

STUDENT NOTE BOOK FORMATIVE EVALUATION SHEET IMMUNOLOGY AND INFECTION MODULE – ACADEMIC YEAR 2008-2009 (to be submitted to module coordinator at the end of each trigger)

TRIGGER* : 1 – 2 – 3 – 4 Group : ..............................................

STUDENT’S NAME EVALUATION **

POOR GOOD

1 2 3 4

1

2

3

4

5

6

7

8

9

10

*circle the right trigger **tick () the appropriate column FACILITATOR (................................................) NOTE: STUDENT THAT GETS 2 CONSECUTIVE POOR EVALUATIONS WILL BE SUMMONED BY THE MODULE COORDINATOR

Instructional Design Book, Immunology and Infection Module, FMUI 2012 47

FACULTY OF MEDICINE, UNIVERSITY OF INDONESIA SUBPROGRAM GENERAL EDUCATION SUBPROGRAM INTEGRATED MEDICAL SCIENCES

PRACTICAL WORK REPORT SHEET Immunology & Infection Module

Experiment: …………………….. Date: 2009 Time: ….. - ….. Group ….. Supervisor : ……………………

No. NAME Team Work

Participation

Discipline

Result Quality

Total Score (Mean Value)

1. 2. 3. 4. 5. 6. 7. 8. 9. 10.

Note: Range of Score = 0 - 100

Range: <6 = Poor 6 – 6,9 = Bad 7 – 7,9 = Average 8 – 8,9 = Good 9 – 10 = Excellent PRACTICAL WORK SUPERVISOR (..............................................................................)

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