GROUP NAME- PHARMACOGNOSY & ETHNOPHARMACOLOGY

1. Objectives:

a) Standardization and quality evaluation of herbal raw drugs/ formulations.

b) Identification of elite chemotypes of medicinal plants.

c) To study the effect of season on medicinal plants.

d) To validate the ethno-medicinal claims.

e) To develop scientifically validated standardized herbal products based on traditional knowledge.

2. Goals:

a) Preparation of monographs of medicinal plants. b) Identification markers of adulterants/substitutes of ASU drugs. c) Identification of elite chemotypes with maximum concentration of identified

bioactive markers. d) Determination of the best season of collection / harvesting of industrially important

medicinal plants for commercial exploitation. e) Development of scientific validated standardized pharmaceutical/ nutraceutical/

cosmaceutical herbal products.

3. Competencies:

The group has experienced team of scientists and technical staff specialized in Pharmacognosy, Pharmacology, Chemotaxonomy, Chemistry and Pharmacy. The team has following expertise to fulfill the objectives and to achieve the goals.

Taxonomic identification of plants and it parts

Macro- microscopical details along with the quantitative microscopy & microphotography

Histochemical analysis of the plant parts used as medicine

To develop physico-chemical standards viz. Foreign matter Ash values (Total ash, sulphated ash, acid insoluble and water soluble ash) Extractive values (I.P. method) Estimation of alkaloids, total phenolics, tannins, sugars, starch and protein

etc. of crude as well as finished herbal drugs/products.

Preliminary phytochemical screening for the presence of alkaloids, anthraquinones, glycosides, sugars, phenolics, tannins, saponins, steroids and terpenoids etc

To develop chemical markers for Identification, quality and batch-to-batch consistency with the help of HPTLC, HPLC, GLC & DNA finger printings etc.

To detect the microbial contamination including the detection of mycotoxins and heavy metals and pesticide residue in herbal drugs (raw as well as finished) in

accordance with the WHO guidelines.

To develop the monographs of medicinal plants.

To develop the SOP’s of Ayurvedic formulation & their Pharmacopoeial monographs.

Pharmacological evaluation to cover the therapeutic efficacy & safety aspects or toxicity Antistress Antioxidant Anti-diarrheal & antiulcer Hepatoprotective Diuretic Immunomodulating Antimicrobial activities

4. Facilities:

Authentication of raw drugs.

Quality control & standardization of herbal drugs/products.

Pharmacological screening of herbal drugs/formulations.

National Accreditation Board for Testing and Calibration Laboratories (NABL) Accreditation Lab

5. Highlights of Current Research:

The Pharmacognosy and Ethnopharmacology division, CSIR-NBRI, Lucknow is a multidisciplinary and applied research division with the objective of establishing a state-of-the-art expertise facilitating in plant product research with special reference to standardization & quality evaluation of ASU drugs and plant-based herbal drugs/products.

Search for elite chemotype of Plumbago zeylanica L.

Plumbago zeylanica was selected for identification of elite chemotypes/germplasms with maximum concentration of identified bioactive marker and also determination of its agro-climatic conditions suitable for the elite chemotypes/ germplasms vis-à-vis their ecology in the natural habitats. A bioactive component plumbagine has been identified from this plant for estimation.

Seasonal variation studies on plant Tephrosia purpurea (L.) Pers.

Tephrosia purpurea, an annual plant, recently has attracted the attention, for its

hepatoprotective and stimulant activity, was selected to study the effect of season on plant and

active constituents responsible for the therapeutic action of the plant and to determine the best

season and time of collection. Phytochemical evaluations for marker compounds have led to the

identification of lupeol, β-sitosterol, rutin and rotenone in its extracts which will be taken up for

seasonal variation studies.

Pharmacognostic evaluation of ‘Saalparni’-

Saalparni, consists of roots of Desmodium gangeticum (L.) DC., but roots of other plants viz. D.

triflorum (Linn.)DG, D. velutinum (Willd.) DC are also used or reported as ‘Saalparni’ in different

parts of India. The pharmacognostic evaluation of aforesaid three Desmodium species was

carried out by using macro-microscopic details, physico-chemical analysis and HPTLC

fingerprinting along with the solasodine, stigmasterol and lupeol marker compounds.

Development of Cosmaceuticals products:

1. TS Root 2. TS Root 3. TS Root

1. 2. 3.

Macro-Microscopy of ‘Saalparni’

1. Desmodium gangeticum; 2. D. velutinum; 3. D. triflorum

Physico-chemical Analysis of ‘Saalparni’

HPTLC fingerprints of ‘Saalparni’

1. Desmodium gangeticum; 2. D. velutinum; 3. D.

triflorum; R1, Solasodine; R2, Stigmasterol; R3,

Lupeol

o Herbal colours for cosmetics: Lipophilic Strawberry red colour was isolated from the plant NBR-R1 and standardized along with safety studies for application in lip balm.

o Natural Lip-Balm- Technology developed jointly by CSIR-NBRI & CSIR-CIMAP. Herbal colour and natural ingredients used in lip balm protect the lips and leaves the lips hydrated and nourished by preventing moisture loss. Natural lip balm is non toxic.

o Technology developed for Yellow colour – Lipophilic yellow colour was also isolated from the plant NBR-Y for its application in lip butter/balm. Mango flavoured, Vitamin E enriched Yellow Lip balm developed jointly with CSIR-CIMAP. It keeps the lips healthy and color is safe. Further, this know how is also ready to license to the company after QC and safety studies.

Network Projects:

Survey and collection tours were conducted to Govind Wild Life Sanctuary. Two plant

samples, NBC10 and NBC 11 were collected from the natural habitat of and passport data

sheets were prepared. The samples were extracted separately with 95% alcohol, 50%

aqueous alcohol and water. Further the plant samples were subjected to estimation of

total phenol, antioxidant activity and HPTLC fingerprinting. The extracts were sent to CDRI

for single dose primary screening against different cancer cell lines viz breast, liver, colon,

ovary, brain, pancreas and prostate.

The extract exhibiting antidementia activity was taken up under Fast Track mode for detailed studies. The extract exhibited significant preventive potential. In order to

HPTLC fingerprints of NBC11 Extracts

along with the biomarker

1 2 3 4 5 6 R 7 8 9 10 11

12 HPTLC fingerprints of NBC10 Extracts

along with the biomarkers

1 2 3 4 5 6 R1 7 8 9 10 11 12

R2

enhance the curative potential of the active fraction, a well known plant showing antioxidant activity was selected. It was found that the combination exhibited preventive as well as curative properties.

Under NAIP funded project ‘Studies on relationship between ecogeography of the

chemotypic variation of nine important but highly threatened medicinal plant species and

prospects of their cultivation’ we aimed to identify the best suitable agro-climatic

conditions for cultivation of nine industrially important medicinal plants in different

phytogeographical zones of the country and also their relationship with secondary

metabolites. During the project tenure more than 296 accessions of Tribulus terrestris,

Acorus calamus,Sida cordifolia, Desmodium gangeticum, Asparagus racemosus, Gymnema

sylvestre, Hedychium spicatum, Origanum vulgare and Valeriana jatamansi were collected

from different phytogeographical regions of the country. On the basis of secondary

metabolites (bioactive molecules); 8 elite accessions/chemotypes of above mentioned plant

species were identified.

Under NAIP funded project ‘Novel Approaches for Production of Nutraceuticals from Milk

and Indian Herbs for Potential Use in Functional Dairy Foods’, three Indian herbs (NBD-1,

NBD-2 and NBD-3) were selected for incorporation in functional dairy foods in a form

compatible to milk systems. Different milk combinations with Pueraria tuberosa were

prepared by homogenizing pasteurized toned milk with its ethanolic and hot water extracts

and their stability with reference to pH and coagulation was studied over a period of 15

days. The Kudzu-fortified milk combinations were also analyzed for puerarin, the major

isoflavone C-glucoside present in P. tuberosa, through high-performance liquid

chromatography using photo diode array detector. It was observed that there was no

precipitate formation and the pH also did not change during the study period indicating

their physical stability under the experimental conditions. Also there was no significant

change in the content of Puerarin during the study period, thereby indicating the chemical

stability of the samples. These studies will be useful for developing milk nutaceuticals

fortified with Indian Kudzu which has the potential to be included as an ingredient in health

and functional foods.

Under the project ‘Identification of Potential Antimutagenic Phytochemicals form weeds and Agri-wastes’, antioxidant potential of 50% ethanolic extract of selected agro wastes (Mangifera indica, Litchi chinensis, Citrus reticulate, Aegle marmelous and Musa paradisiaca) was assessed. The yield of the extract varied over a wide range (8.80 to 29.9 g/100g of dry weight). Total phenolic content (TPC), total flavonols, kaempeferol, quercetin, myricetin HPLC method). DPPH radical scavenging and inhibition of linoleic acid peroxidation of the extracts varied significantly ranging from 1.9-36.40, 0.26-4.89 g/100g of dry matter, 11.2-52.6, and the highest TPC, TFC and total flavonols exhibited superior antioxidant activity followed by Aegle marmelous, Litchi chinensis,, Mangifera indica, Citrus reticulate, and Musa paradisiacal. The increase in level of antioxidant profile i.e. superoxide dismutase (SOD) , catalase , glutathione reductase (GR) and glutathione peroxidase (GPx) by the natural extract may be attributed to have biological significance in eliminating reactive free radical that may affect the normal functioning of cell. The

isolated bioactive fraction from Litchi chinensis showed rich in antioxidant in mucosal tissue and may helps to reduce the risk of cardiovascular disease, cancer, stroke and aging.

Under the project ‘Search for elite chemotype(s) of industrially valuable threatened

medicinal species and their relationship with ecogeography’, total of 72 accessions of

Centella asiatica have been collected from different phyto-geographical zones of the

country and studied. Variations were observed and recorded. Among all the collected 72

accessions, two morphotypes (CA-09 & 10) has been identified. Qualitative phytochemical

screening and quantitative estimation of secondary metabolites using conventional

methods of HPTLC on these 72 accessions for their bioactive chemical constituents showed

elite accessions CA-15 & CA-45 for Asiaticoside, CA-45 & CA-51 for Madecassoside and CA-

07 for Asiatic acid. Among all the collected 72 accessions, three elite accessions have been

identified.

6. List of Ongoing projects: NBRI In house project:

1. Quality Evaluation And Scientific Validation Of Indigenous Indian Medicinal Plants

Having Industrial Application (Pharmaceutical, Nutraceutical, Cosmaceutical) And Development Of Herbal Product(s) Based On Traditional Knowledge- In-House Project (OLP 0089)

2. “Bioprospection of plant resources and other natural products (BioprosPR)”- Network Project (BSC 0106)

3. Studies on relationship between ecogeography of the chemotypic variation of nine important but highly threatened medicinal plant species and prospects of their cultivation”. GAP-274725 (NAIP/ICAR)

4. Study of herbal acaricides as means to overcome the development of resistance in ticks to conventional acaricides. GAP-274825 (NAIP/ICAR)

5. Novel Approaches for Production of Nutraceuticals from Milk and Indian Herbs for Potential Use in Functional Dairy Foods. GAP-275325(NAIP/ICAR)

6. Identification of Potential Antimutagenic Phytochemicals form weeds and Agri-wastes - UPCST Lucknow (GAP- 274525)

7. Reviving traditional remedies for age dementia disorders in elderly: Documentation and dissemination of ancient Indian wisdom as mentioned in Ayurveda. DST (GAP - 275625)

8. Identification and biological studies of potential bioactive constituents from important medicinal plants (Aegle marmelos) used in gastrointestional disorders

and their geographical variations in chemical markers. GAP-275025 (NMPB, Dept. of AYUSH, New Delhi)

9. Identification of substitutes for traded drug Chirayata (Swertia species) using pharmacognostic and pharmacological parameters. GAP-275125 (NMPB, Dept. of AYUSH, New Delhi).- Completed

10. Search for elite chemotype (s) of industrially valuable threatened medicinal species and their relationship with ecogeography. OLP-077 (CSIR-EMPOWER Scheme)- Completed

11. Preparation and supply of Botanical References Substances (BRS) to Indian Pharmacopoeia Commission (IPC) New Delhi. (Sponsored by Indian Pharmacopoeial Commission, Govt. of India, Ghaziabad, U.P.) GAP-275425--Completed

12. Discovery and preclinical studies of new bioactive molecules (Natural and semi-synthetic) & traditional preparations. NWP-0037. (CSIR) -Completed

13. Rural School Heath Education programme integrating with diverse inputs Reaching the Unreached. MLP-0006 (sponsored by CSIR)- Completed.

14. Biodiversity assessment, prospection and conservation of plant resources of India. SIP-05. (CSIR) - Completed.

Outside agencies like DBT / DST / MOEF etc. :

7. Significant achievements: Upto 11th Five year Plan:

Over 350 raw single herbal drugs and about 50 polyherbal formulations have been standardized. Some of the pharmaceutical important raw drugs evaluated are ‘Amra haridra’, ‘Ashoka’, ‘Arjuna’, ‘Ativisha’, ‘Bala’, ‘Bhuiamla’, ‘Bilva’, ‘Brahmi’, ‘Chiraita’, ‘Dashmoola’, ‘Daru Haridra’, Deodara’, ‘Dronpushpi’, ‘Gokshru’, ‘Hansraj’, ‘Jivanti’, ‘Kali Musali’, ‘Kalmegh’, ‘Kesar’, ‘Khatmi’, Kulanjana’, ‘Kurchi’, ‘Manjishtha’, ‘Punarnava’, ‘Safed Musli’, ‘Salam Panja’, ‘Sapan’, ‘Satawar’, ‘Siris’, ‘Talispatra’, ‘Vacha’, ‘Vasa’ and ‘Vidarikand etc

Monographs on Quality Standards of Important Indian Medicinal Plants published in The ‘Ayurvedic Pharmacopoeia of India’ and ‘Quality Standards of Indian Medicinal Plants’ and SOP’s of Polyherbal ASU formulations & their Pharmacopoeial standards were published.

HPTLC/HPLC methods have been developed for estimation of biomarkers in several important medicinal plants/formulations for their standardization and quality control. Some of them are Mangifera indica, Heracleum candicans, Syzygium aromaticum, Strychnos nux-vomica, Myrica esculenta, Dendrophthoe falcata, Bergenia sps., Sida sps., Phyllanthus sps., Adiantum sps., Terminalia sps., ‘Chyavanprash’, ‘Triphala’, ‘Kalmeghasava’, ‘Ashokarishta’ etc.

SOP’s and standardization of some Ayurvedic formulations such as ‘Chyavanprash’, ‘Puga khand’, ‘Ashtangavaleha’, ‘Kalmeghasava’, ‘Chitraka Haritaki’, ‘Hingawastaka Churna’, ‘Kaiśhora guggulu’, ‘Punarnava guggulu’, ‘Mahakalyanaka Grita’, ‘Vidariyadi Grita’, etc. have been done.

A new methodology for mass production of seedlings as developed for Hedychium spicatum

and Valeriana jatamansi will benefit the farmers for profitable cultivation. Two alternative

species of Tribulus terrestris have also been identified from the arid zone of country with

common secondary metabolites (protodioscin, prototribestein and tribulosin).

Pharmacological and toxicological screenings of herbal extracts/formulations in various experimental animal models were performed. Around 50 medicinal plants were screened for Antiulcer and antidiarrhoeal activities in various animal models. Plant extracts showed significant antiulcer potential are Musa sapientum, Ficus racemosa, Annona squamosa, Utleria salicifolia, Aegle marmelos, Cinnamomum tamala, Buchanania lanzan etc. Plant extracts were subjected for the screening of anti HCC in Nitrosodiethylamine induced hepatic damage in experimental rats and Fumaria indica showed significant activity. Throat soothing anti-cough herbal syrup was prepared and standardized the method for manufacturing. The extracts were processed and formulated as anti-ulcer herbal combination and wound healing ointment.

Antioxidant activities by both in vitro and in vivo models of around 100 plants and formulations have been carried out. Developed a photochemilumescent based assay for the

Part-I, Vol.-V Part-I, Vol.-V (Atlas) Part-II , Vols.-I – III Vols.-I – VIII

NBRI’s contribution:

13 monographs 43 monographs 20 Formulations 54 Monographs

screening of antioxidant activity of colored plant extracts using the Photochem apparatus. Plant extracts showed significant antioxidant potential are Acorus calamus, Asparagus racemosus, Anogeissus latifolia, Desmodium gangeticum, Piper longum, Piper cubeba, etc.

Under the CSIR Inter-Laboratory network project 250 parts of 135 plants were collected in bulk and extracted with 95% ethanol, 50% aqueous ethanol and hot water. 12750 samples were sent to various CSIR labs for bio-evaluation. Six plant extracts/fractions were found promising for anti-dementia, anti-filarial, anti-malarial, anti-tuberculosis, anti-psychotic activities and 14 extracts showing anti-termite activity.

Jointly with other CSIR Labs prepared standardized novel herbal based formulations for degenerative disorder viz. Osteoarthritis and Rheumatoid Arthritis, Diabetes mellitus type II (NIDDM) and Common hepatic disorders under NMITLI projects.

Various Training programs organized for the Scientists, Teachers & Paramedic of AYUSH, and Students on the aspects of ‘Quality Evaluation of Herbal Drugs/Products’.

Conducted several awareness programs among the rural masses including the school children and educating them about the importance of medicinal plants and indigenous knowledge for their health care needs.

Established Indian Herbal Garden at WHO (Hq.) Geneva (Switzerland) with the aim to popularize plants of Indian Traditional Systems of Medicine, under National Medicinal Plants Board project.

Two books namely ‘Package of Practices for Organic Cultivation & Utilization of Important Medicinal Plants’ (Part-I) and ‘Bark Drugs’ Vol. 1 under also published by the Division.

A view of Indian Herbal Garden developed by CSIR-NBRI at Geneva.

Technology developed:

Wound healing Herbal

Composition

Strawberry red herbal

colour for lip balm

Lipophilic Yellow colour for

cosmaceuticals

Natural Lip balm Jointly developed by

CSIR-NBRI & CSIR-CIMAP

Herbi-Chew Jointly developed by

CSIR-NBRI & CSIR-CIMAP

Herbal soft health drink Herbal Anticough

Formation Antiulcer Herbal

Composition

Fruit based fermented

health drink

Nutri-Jam

Technology transferred:

Natural lip balm- transferred to M/S. Chaira Herbals Pvt. Ltd., New Delhi. Strawberry red herbal colour for lip balm - transferred to M/s Himalaya Drug Company,

Bangalore. Anticough Syrup- transferred to M/s. Toral Herbals, Lucknow (U.P.) Herbal colours for cosmaceuticals- transferred to M/s. Ayur Herbals, Alwar (Raj.) Fermented health drink- transferred to M/s. ANJS Exports, Kanpur (U.P.) Anticig - transferred to M/s. MIR Holistics Pvt. Ltd., Kochi (Kerala)

In 12th five year plan:

Recent Publications

1. M.M. Pandey, A. Katara, G. Pandey, Subha Rastogi and A.K.S. Rawat. “An Important Indian Traditional Drug of Ayurveda Jatamansi and Its Substitute Bhootkeshi: Chemical

Herbal Lipsticks

Profiling and Antioxidant Activity.” Evidence-Based Complementary and Alternative Medicine, 2013, vol. 2013, Article ID 142517, 5 pages, 2013. doi:10.1155/2013/142517.

2. Sharad Srivastava and AKS Rawat. Quality evaluation of Ayurvedic crude drug

Daruharidra, its allied species and commercial samples from herbal drug markets of

India. Evidence-Based Complementary and Alternative Medicine (e-CAM). 2013, Article

ID 472973. DOI:10.1155/2013/472973

3. Shweta Singh, Sayyada Khatoon, Harsh Singh, S. K. Behera, P. B. Khare, A. K. S. Rawat. A report on pharmacognostical evaluation of four Adiantum species, Pteridophyta, for their authentication and quality control, Revista Brasileira de Farmacognosia (Brazilian Journal of Pharmacognosy) 23(2): 207-216, Mar./Apr. 2013.

4. Sawale Pravin Digambar, Ram Ran Bijoy Singh, Suman Kapila, Sumit Arora, Subha Rastogi and Ajay Kumar Singh Rawat. “Immunomodulatory and antioxidative potential of herb (Pueraria tuberosa)-milk model in mice.” International Journal of Dairy Technology, 2012, vol 65. Article first published online: 29 OCT 2012 | DOI: 10.1111/1471-0307.12011 1.107

5. Neeraj V, G Amresh, P K Sahu, Ch V Rao, A P Singh. Anti-hyperglycemic activity of Woodfordia fruticosa (Kurz) flowers extracts in glucose metabolism and lipid peroxidation in streptozocin –induced rats. Indian Journal of Experimental Biology 50, 2012, 351-358.

6. Srikant Ghosha, Shashi Shankar Tiwari, Sharad Srivastava, Anil Kumar Sharma, Sachin Kumar, D. D. Ray, A.K.S. Rawat. Acaricidal properties of Ricinus communis leaf extracts against organophosphate and pyrethroids resistant Rhipicephalus (Boophilus) microplus. 2013, Veterinary Parasitology 192: 259– 267.

7. Shashi Shankar Tiwari, Madan Mohan Pandey, Sharad Srivastava and AKS Rawat. Simultaneous determination of Picrosides (Picroside-I and Picroside-II) in Picrorhiza kurroa and its substitute Picrorhiza scrophulariiflora through High Performance Thin layer Chromatography. 2012, Biomedical Chromatography, 26 (1): 61–68.

8. T. S. Rana, Kamalesh S. Mahar, M, S. K. Srivastava and A. K. S. Rawat. Molecular and chemical profiling of 'sweet flag' (Acorus calamus L.) Germplasm from India. 2013, Physiology and Molecular Biology of Plants. 19:231-237.

9. Anil Kumar Sharma, Rinesh Kumar, Sachin Kumar, Gaurav Nagar, Nirbhay Singh, Sumer Singh Rawat, M.L. Dhakad, Rawat A.K.S., Ray, D.D., Srikant Ghosh. Deltamethrin and cypermethrin resistance status of Rhipicephalus (Boophilus) microplus collected from six agro-climatic regions of India. 2012, Veterinary Parasitology, 188: 337-345.

10. Sunil K. Jaiswal, Chandana V. Rao, Brijesh Sharma, Pritee Mishra, Sanjib Das, Mukesh K. Dubey Gastroprotective effect of standardized leaf extract from Argyreia speciosa on experimental gastric ulcers in rats. Journal of Ethnopharmacology, 137 (1), 2011, 341-344.

11. Sanjeev Kumar Ojha, Pramod Kumar Sahu, Sri Krishna Tewari : Health through herbs Applied Botany Abstract, Vol. 31 (3):255-260. 2011.

12. A.K. Agnihotri, Shital K. Sharma, S. Khatoon and A.K.S. Rawat Validation of Traditional Claims of Ashwagandha (Withania somnifera) - The Indian Ginseng. Applied Botany Abstract, 31(2):160-180. 2011.

13. Mansi Gupta, Deepa Bisht, M.M. Pandey, S.K. Ojha, S. Khatoon, Subha Rastogi and A.K.S. Rawat. “Standardization of Ashwagandhadi lehya — an Important Ayurvedic Formulation of Withania somnifera.” Indian Journal of Traditional Knowledge, 2011, 10(4): 594-598.

14. Subha Rastogi, M.M. Pandey and A.K.S. Rawat. “An Ethnomedicinal, Phytochemical and Pharmacological Profile of Desmodium gangeticum (L.) DC. & D. adscendens (Sw.) DC.”. Journal of Ethnopharmacology, 2011, 136: 283–296.

15. Khatoon Sayyada, Singh Harsh, and Goel A.K. Use of HPTLC to Establish the Chemotype of a Parasitic Plant, Dendrophthoe falcata (Linn. f.) Etting. (Loranthaceae), Growing on Different Substrates. Journal of Planar Chromatography, 2011, 24 (1) 60-65.

Staff:

Dr. A.K.S. Rawat Senior Principal Scientist & HOD Dr. Ch.V. Rao Principal Scientist Dr. Sayyada Khatoon Principal Scientist Dr. Sharad Srivastava Senior Scientist Dr. Subha Rastogi Senior Scientist Dr. Sanjeev Kumar Ojha Senior Scientist Dr. Brahma Nand Singh Scientist Dr. Madan Mohan Pandey TO Mr. Ram Gopal Pandey Helper

Research Fellows/Project Assistant:

Ms. Nishi Srivastava CSIR-SRF Ms. Saba Irshad ICMR-SRF

Ms. Monika Sharma DST-Inspire JRF Mr. Siddhartha Pragyadeep UGC-JRF Ms. Garima Pandey Project Assistant Level-III Ms. Archana Rai Project Assistant Level-III Ms. Shweta Singh Project Assistant Level-II Mr. Abhishek Gupta Project Assistant Level-II Mr. Shikhar Verma Project Assistant Level-II Mr. Pramod Kumar Singh Project Assistant Level-II

Source of Funding

CSIR

DBT

DST

National Medicinal Plant Board, Dept. of AYUSH, New Delhi

Dept. of AYUSH, New Delhi

NAIP/ICAR (World Bank)

UPCST

Foreign Collaboration:

Bio-Asia Program of France, Thailand & India.

Training provided to WHO Fellows from Mayanmar.

Areas open for collaboration:

Authentication, Quality evaluation and standardization of herbal drugs.

Development, value addition & standardization of Pharmaceutical, Nutraceutical and

Cosmaceutical products of Industrial importance.

Validation of Ethnobotanical claims.

Name of the Group Leader: Dr. AKS Rawat, Senior Principal Scientist & HOD

Phone: 0522-2297816

Fax: 0522- 2205836

E-mail: rawataks@rediffmail.com; a.k.s.rawat@nbri.res.in