Grass Roots Initiatives

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    For 30 years, the paediatric ward of theKhmer Soviet Friendship Hospital

    stood crumbling at the southern end ofthe Cambodian capital Phnom Penh.

    In 2008, supported largely by private dona-tions, the Cambodian Health Committee,a non-governmental organization (NGO),transformed the ward into the Sullivan Out-patient Center for children with HIV andtuberculosis (TB). Later that year, MdecinsSans Frontires (MSF) entrusted the care of205 HIV-positive children to the centre.

    Now called the Global Health Committee(GHC), the Cambodian group was born in 1994at a refugee camp on the CambodiaVietnamborder. The genocidal Khmer Rouge regime

    targeted health-care professionals, so, when itsreign ended in 1979, those who survived wereleft with no medical infrastructure.

    Since its inception, the GHC has caredfor more than 5,000 HIV patients and cured25,000 people of TB, says Anne Goldfeld, thegroups co-founder and professor of medicineat Harvard University. With donors rang-ing from the drug company Eli Lilly to theUnited Nations World Food Programme andthe US National Institutes of Health, the GHCprovides medicines, meals and care for anestimated 15,000 people. The group managesfive centres for HIV and TB care and research

    in Cambodia, stretching from rural provincesto Phnom Penh.

    Community involvementIn 2008, the group expanded its model toEthiopia. Staff members have also visitedrefugee camps in Pakistan, and are discussingplans to move into Swaziland and Vietnam.Their approach differs from other missionsthat deliver care after war, says Paul Hamil-ton, project director at an aid organization inUganda, who is not affiliated with the GHC.I think their commitment is longer and theyreally work on incorporating the community.

    And the second thing that is really different isthat they do a lot of basic research.

    Many international medical NGOs are inthe process of leaving Cambodia. At times like

    these, the [GHC] becomes more important.says Didier Laureillard, a physician specializ-ing in HIV and TB at the European GeorgesPompidou Hospital in Paris, who volunteeredwith MSF in Cambodia.

    The group owes its success inCambodia in part to sustaina-bility brought about by trainingand working with the commu-nity. Its staff members visit patients at homeand enlist local health-care workers to monitorthe nutritional quality of meals eaten by thosereceiving antiretroviral drugs from its clinics.

    Goldfeld also initiated basic research in the

    mid-1990s. Her team is conducting a clinicaltrial on the ideal time for those co-infected withTB and HIV to begin taking AIDS drugs.

    There were a lot of people who doubtedour ability to do it because Cambodia had noinfrastructure, she says. Not only did we end

    up recruiting 661 patients but, whats more,weve enhanced care all over Cambodia for TBand AIDS.

    Fighting the brain drainGoldfeld has mentored local clinicians inwriting proposals, designing studies andpublishing results. That training is bound tohave a broader impact, says Kristian Olson, aclinician educator at Massachusetts GeneralHospital and health advisor for the GHC.

    If you create this cadre of inquisitivephysician scientists that are driven to answercompelling questions, youll do a lot for staff

    retention and reverse the brain drain, Olsonsays.

    Olson volunteers with GHCs outpost inAddis Ababa, set up with the Ethiopian Min-

    istry of Healths approval, tocombat HIV and TB. Accord-ing to a 2008 World HealthOrganization report on Ethio-pia, 40% of TB patients tested

    there were HIV-positive.The Cambodian team has repeatedly visited

    Addis Ababa to train local doctors. Last year,with funding from the JoliePitt Foundation,it opened the Zahara Childrens Center for

    HIV-positive kids modelled after the groupssimilar Maddox Chivan Childrens Center inCambodia.

    With some tweaks, the GHCs model forbuilding medical infrastructure will workin any impoverished, war-torn country, saysSok Thim, a former Cambodian refugee andthe groups co-founder. We have the modeland the means to deliver it, Thim says, Wewant to help wherever there is great need forTB care.

    Extending models to other countries isharder than it sounds, cautions Hamilton. Iveseen good models work in one country but not

    transfer to another. For example, he says, theEthiopian government is wary of NGOs. Yet those affiliated with the GHC say it has suc-ceeded in Ethiopia partly because it works inpartnership with the Ministry of Health.

    As a survivor of the killing fields, povertyand TB, Thim relates to the frustrations ofEthiopian health-care workers, Olson says.

    Care providers in Addis Ababa see Thim asa medical expert who easily could have beenthe poor refugee, says Olson. After trainingwith Thim, Olson says, I heard them goingfrom no confidence to feeling like they will be[part of ] a centre of excellence. nAmy Maxmen is a freelance writer in New York

    City.

    GrassrootsinitiativesA Cambodian group has developed a pioneering

    community-based approach to HIV and TB care and

    research. Amy Maxmen describes how this powerful

    model is being expanded to other war-torn countries.

    The Cambodian group has cared for many

    children infected with HIV and tuberculosis,

    including Ye How (at age six in 2006, top; andafter successful treatment a year later, bottom).

    GHC

    They really work

    on incorporating the

    community.

    HIV worldwide

    S20

    15 July 2010OUTLOOKHIV/AIDS

    www.nature.com/outlooks