GRAS Magazine | issue 1

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ALL AMERICAN PET BRANDS

SILKY cLeanISn’T GeRM FRee Page 8

GENERALLY REGARDED AS SAFE

How oFTen Do I BaTHe MY DoG?Page 5

GeRMS aRe eVeRYwHeReaLL THe TIMe Page 25

InTeRcepTInG THe MIcRoBeS can HuRT uS Page 30

#1 2013

Warm water is no more

effective than cold for removing

germs. More importantly, while

soap and water will remove

dirt, neither kills germs. The

ingredients in soap will help wash

most, but not all of the millions of

germs from the surface of your

dog’s skin and coat. That’s both

a good and a bad thing as many

germs are actually good for us,

but the few that are dangerous

require more than a soak in the

suds to remove the potential

for infection they present.

Equally important to note, the

oils on your dog’s coat are an

important natural protection

barrier. Frequent washing will

not only remove those essential

oils, but expose skin, glands and

tissues to irritation, disease and

severe drying which will promote

scratching and sores. The

solution to harmful germ removal

is hypoallergenic, alcohol free,

antibacterial PAWTIZER. It is,

according to the FDA, GeneRaLLY ReGaRDeD aS SaFe (gRaS)

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GeneRaLLY ReGaRDeD aS SaFe (gRaS)

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GRAS #1 2013

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GRAS #1 2013

Improper bathing can cause dog’s dry dog skin. Dry skin occurs when too much bathing or bathing with harsh products strips your dog’s skin of its natural oils. Symptoms of dry skin include itching, redness, hair loss, hot spots and infection. First evaluate whether serious underlying health conditions are caus-ing your dog’s dry skin and treat any you find. Whatever the cause of dry skin, implement the right bathing schedule and use the right products to repair and rejuvenate your dog’s dry skin.

Too much of a clean Thing, iSn’T a good Thing.

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How often Do I BatHe My Dog?There is no one right answer to this question. As a general rule, dogs need to take baths far less often than humans do. Depending on the breed and length of coat, as well as general health status of your dog, you and your vet will decide on the appropriate bathing schedule.

Use tHe RIgHt sHaMpoos foR DRy skInNever use shampoos formulated for humans or dish-washing liquid to bathe your dog; such products are too harsh and have the wrong pH for dogs. Choose canine-specific, soap-free and pH-balanced sham-poos and 99/9% effective PAWtizer antibacterial wipes.

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GRAS #1 2013

It onLy takes ten geRMs to Infect

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It is not the length of time we are exposed, or by whom we become exposed or how we are exposed to pathogens as it only takes ten microscopic organisms to impact the health of the healthiest child or adult with a threatening disease innocently carried and transmitted by our pet children to our families.

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GRAS #1 2013

1Switch to a high-quality dog food. Premium food has a type of meat listed as the first ingredient. Protein is essential to a healthy coat.

2A lack of omega-3 and omega-6 fatty acids could be the reason its coat is not shiny.

SilKY

iSn’T GeRM FRee

3If you have a long-haired dog, you might need to brush it daily to avoid tangles and keep the hair soft and healthy. Grooming doesn’t mean washing, though – dogs’ coats have natural oils that keep them from getting too dry. If you bathe your dog too often, you might end up stripping those oils and causing the hair to look dry and dull.

clean

GENERALLY REGARDED AS SAFE

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5A weak immune system, skin parasites or infections can affect the look and health of the coat. Treating the issue with medication will eventually make the coat shinier and healthier.

4Switch to a two-in-one doggie shampoo, which comes

with added conditioners. Just like you use

conditioners in your own hair to improve its softness

and shine, When giving a bath, remember to rinse

well – if there are remnants of shampoo on the hair,

it can make it look dull and dry.

6PAWtize – alcohol free, soap free, ph neutral hypoal-lergenic benzalkonium chloride 99/9% effective against contagious pathogens.

clean

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GRAS #1 2013

Benzalkonium chloride-based hand sanitizer products are considered to be an ideal and actually a safer alternative to legacy, alcohol-based products. Commonly referred to as “BZK” or “BAC”, this organic compound is the common ingredient in most OTC antiseptics (e.g. Bactine), and is often the active ingredient in nasal spray and contact lens.

Numerous independent lab studies evaluating BAC within a hand sanitizer application have found these products are not only equally effective against a broad spectrum of pathogens (including flu, HIV, Salmonella, Hepatitis, etc.), but are safer to the skin. It is important to note that the CDC recommendations for water-less hand cleansers were established in 1994 and thus do not reflect the current studies in non-alcohol anti-microbials such as Benzalkonium chloride. The latest generation products are more effective and much safer than alcohol based sanitizers. Low compliance with hand sanitizer use in medical professionals is directly related to the adverse impact alcohol has on the skin. Additives such as gels, Aloe and Vit. E merely mask the extreme drying effect of alcohol.

o.13%

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While alcohol does kill germs, it also kills protective skin cells intended to defend against bad bacteria. Alcohol has no persistency. Once it dries (which is within seconds), it stops being effective. Alcohol-based products do not penetrate dirt – which is why leading makers (Purell) caution consumers to wash their hands prior to applying. Leading anyone to ask “If I should wash my hands before applying, why would I apply something kills my skin?” and leading

a continuously growing group of experts to conclude that BAC-based hand sanitizer products are the pragmatic choice when washing with soap and water is not readily available. While all hand sanitizers should be used as directed, alcohol based sanitizers pose a significantly higher safety risk in terms of flammability, poisoning from accidental ingestion and skin degradation…to people and most importantly our dogs.

MoRe eFFecTIVe anD SaFeR THan aLcoHoL

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GRAS #1 2013

BZcl

The combination of a continuous stream of academic and research studies pointing to the “downside” of alcohol-based hand sanitizers, coupled with heightened awareness on equally-effective, yet safer, environmentally friendlier, and arguably, more cost-efficient hand sanitizer products has resulted in a major shift away from flammable, alcohol-based products, and towards alcohol-free products.

A Nielsen Co report showed the retail market of hand sanitizer during a 52 week period of Swine Flu pandemic generated as much as $180 million, a 70 percent increase from the previous year.

Alcohol-free hand sanitizers most often utilize the organic compound benzalkonium chloride as the active ingredient. Benzalkonium chloride and its cousins have been recognized for a long time as effective antibacterial and antiseptic agents and are proven to be upwards of 99.99 percent effective. It is essentially nontoxic to be applied to the skin or mucous membranes. Benzalkonium Chloride is used primarily in hand or face washes, as well as a disinfectant.

Benzalkonium chloride-based hand sanitizers demonstrated greater sustained degerming activity than gelled alcohol gel hand sanitizers that actually became less effective with repeated use and made the skin dirtier, not cleaner due to removal of protective natural skin oils and entrapment of dead skin cells by the polymer thickeners used in the gelled alcohol products.

non-ToXic / hYPoalleRgenic99.9% effectIVe foR peopLe anD pets

BZcl Lasts LongeR tHan aLcoHoL BaseD HanD wasHes pRoVIDIng sUstaIneD pRotectIon fRoM HaRMfUL geRMs

BZcl wHILe aLcoHoL eVapoRates

IMMeDIateLy, BZcL wILL pRoVIDe

contInUoUs pRotectIon foR

Up to foUR HoURs

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GRAS #1 2013

MRSA

Methicillin-resistant Staphy-lococcus aureus (MRSA) has rapidly become the problem bacteria of the decade. MRSA infections now respond only to very advanced antibiotics that were never meant to be a first-line defense. Usually, the drugs have to be delivered intrave-nously – which often means spending some nights in the hospital. And it doesn’t help that the state of antibiotics is falling behind. With new antibiotics being approved at slower and slower rates, the battle against MRSA has many doctors worry-ing about creating a superbug they can’t kill at all. Now, new data suggest that the MRSA problem may be even worse than we thought.

In a recent study by researchers at the University Health System Consortium (UHC) and University of Chicago Medicine, the rate of MRSA infections recorded at U.S. academic hospitals doubled in the five years between 2003 and 2008. That means nearly 1 in 20 inpatients are now either battling an invasive infection or have been colonized by the bacteria (meaning they carry the germ but don’t suffer from any symp-toms). In each of the last three years, more MRSA-infected people have checked into the hospital than either HIV-positive or influenza-afflicted patients, combined.Most of these patients are likely pick-ing up the bacteria even before they reach the hospital grounds. Accord-ing to a 2010 Centers for Disease Control (CDC) report, infections of invasive MRSA acquired in-hospital fell by 28 percent from 2005 through 2008. Given MRSA’s rapid advance in the face of the CDC’s finding – from 21 infections per 1,000 people to 42 per 1,000 – it’s probably safe to conclude that the increases we’re seeing can be blamed on commu-

nity-associated MRSA, a different strain of the germ. Together, the CDC report and the newer study from the University of Chicago paint two different portraits of the MRSA problem. The first describes the ex-tent of the illness as it actually affects victims today. It only counts serious infections that have penetrated deep into blood or spinal fluid, and makes a point of excluding cases of coloni-zation. The second tries to account for all cases of infection, including colonization, and winds up capturing MRSA’s full potential. Knowing how many people have been colonized by MRSA implies just how many are at risk for consequential illness.

In fact, the Chicago scientists say, the new estimate might even be low-balling the disease’s pervasiveness because the database they use – a collection of insurance bills – tends to under-report instances of MRSA if patients were hospitalized for some other ailment. When the researchers went back to correct for the statisti-cal inaccuracy, they discovered that the insurance claims had missed

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between a third to one-half of actual MRSA cases as re-corded by the hospitals’ own records.At least some of the increase reported in the Chicago paper may simply be due to the fact that we’re now more alert to MRSA than we used to be. Better screening means we’ll find more of what we’re looking for. Still, that doesn’t change the fact that more people in general are becoming carriers for MRSA. Getting infected may not guarantee illness in a specific patient, but it also increases the bacteria’s chances of eventually being spread to someone who will fall ill from an infection. And that’s why understanding the scope of MRSA’s potential – as opposed to measuring only the immediately-consequen-tial cases of MRSA infection – is so important.

%99

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GRAS #1 2013

OUR DOGS INNOCENTLY PICK UP GERMS LIKE A LINT bRUSH AND THEN DEPOSIT THEM ON PEOPLE AND SURFACES WHERE THEY CAN INFECT THE INNOCENT WITH A LICK OR PAT. PAWTIzER’S bzCL SOLUTION SAFELY DE-GERMS DOGS AND PEOPLE OF PATHOGENS WITH A 99.9% EFFICIENCy.

OUR DOGS INNOCENTLY PICK UP GERMS LIKE A LINT bRUSH AND THEN DEPOSIT THEM ON PEOPLE AND SURFACES WHERE THEY CAN INFECT THE INNOCENT WITH A LICK OR PAT. PAWTIzER’S bzCL SOLUTION SAFELY DE-GERMS DOGS AND PEOPLE OF PATHOGENS WITH A 99.9% EFFICIENCy.

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GRAS #1 2013

Although Salmonella and E. coli are

most commonly transmitted through

contaminated food, these pathogens

are some of the zoonotic pathogens

that can be spread between people

and animals. Animals that appear

to be infection free, can carry the

pathogens and pass them through

their feces. The germs easily

contaminate a dog’s fur, skin and

paws as well as the rooms, furniture

and other members of your family

and guests in your home.

Those that become infected exhibit

diarrhea, fever, and stomach pain

5,800 HospItaLs

640,000 tHeRapy Dogs

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1,347,000 that typically appears 1 to 3 days after they become infected. These symptoms typically subside after a week unless they have a weakened immune system and must seek medical assistance as the course of the infection will be more severe. Despite the presence of the germs in and on your dog, it will still appear healthy and clean and that is why PAWtizer must become a part of your dog owning regimen.

InfectIons

640,000 tHeRapy Dogs

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GRAS #1 2013

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aLL anIMaLs caRRy1,000,000 BacteRIa

on tHeIR skIn

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GRAS #1 2013

Animals are the ultimate source for virtually all of the 1.4 million cases/year Salmonella cases. Dogs may suffer sal-monellosis as a “reverse zoonosis,” with infection transmitted from human-to-dog and subsequently back to other humans. Salmonella spp. can be isolated from healthy dogs at rates of up to 36%. That’s one dog in every three pets. Dogs tend to shed Salmonella organisms for very prolonged periods of time after infection. Dogs can shed Salmonella organisms in both their feces and saliva, meaning that transmission can occur via licking.

saLMoneLLaTHE SEVERITY OF THE DISEASE WILL OFTEN DETERMINE THE SIGNS AND SYMPTOMS THAT ARE OVERTLY PRESENT IN THE DOG. SYMPTOMS COMMONLY SEEN IN DOGS WITH SALMONELLOSIS INCLUDE: – Fever

– Shock– Lethargy– Diarrhea– Vomiting– Anorexia– Weight loss– Dehydration– Skin disease– Mucus in stool– Abnormally fast heart rate– Swollen lymph nodes– Abnormal vaginal discharge– Miscarriage or spontaneous abortion

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CHRONIC FORMS OF SALMONELLOSIS MAY

ExHIbIT SOME OF THESE SAME SYMPTOMS;

HOWEVER, THEY WILL bE MORE SEVERE.

THESE INCLUDE SYMPTOMS:

– Fever– Weight loss– Loss of blood– Non-intestinal infections– Diarrhea that comes and goes with no logical explanation, which may last up to three or four days, or longer.

CAuSESThere are more than 2,000 different types of Salmonella, a Gram-negative enterobacteria. Typically, a host animal carrying the disease will have two or more different microorganisms or types of Salmonellae bacteria that cause this disease.Risk factors include the dog’s age, with younger and older animals most at risk due to their underdeveloped and/or com-promised immune systems. Similarly, dogs with weak immune systems or immature gastrointestinal tracts are at risk.Dogs receiving antibiotic therapy are also at risk because the healthy bacteria that line the digestive tract (or florae), may become imbalanced, increasing the risk of salmonellosis.

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GRAS #1 2013

PAWtizer is safe on people, pets and would you believe shoes – it is a 99.9% effective antibacterial agent without any of the dangers or dam-aging drying effects of alcohol. Be safe. PAWtizer.

Dog’s paws, people’s shoes and everyone’s hands are covered with millions of germs. Most of the organisms are of little concern, but it only takes 10 pathogens to infect. Dogs innocently carry our e.Coli, salmonella and MRSA germs on their paws, face and coat. When we get affectionately licked by our dog, or just pet them, the germs are transferred on contact back to us.

EffECTIvE

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Nearly half of all dogs sleep with their pet-parents – few pet-parents wear their shoes to bed. PAWTizer’s Benzalkonium chloride solution de-germs dog paws, fur and people of pathogens with a 99.9% efficiency.

geRMs aRe eVeRywHeReall The Time

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GRAS #1 2013

The great problem with germs is that we can’t leave them behind as we take them every-where we go and oth-ers are waiting for us when we arrive.

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The great problem with germs is that we can’t leave them behind as we take them every-where we go and oth-ers are waiting for us when we arrive.

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GRAS #1 2013

E. coli lives in the intestinal tracts of humans and dogs. Dogs and people can also pick it up from the environment and spread it to other humans and dogs on contact. These animals and people are typically not sick themselves. 0157 is often transmitted by peo-

ple who have an infection but do not wash their hands properly and dogs that have not been degermed that come in contact with people, surfaces and foods that are already contaminated or will become contaminat-ed in their presence.

e.coLI o157

A healthy adult will usually make a full recovery from E. Сoli O157:H7 infection within 5 to 7 days. However, young children, elderly individuals and patients with weakened immune systems can develop potentially fatal HUS (hemolytic uremic syndrome), a type of kidney failure.

Most E. coli strains pose no harm to human health, except for serotype O157:H7, which can cause food poisoning in humans and can become lifethreatening.

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PRODUCT ATTRIBUTES

Protects family membersProvides peace of mindReduces the risk of infectionsReduces the risk of transmissionKills germs and bacteria

Kills 99.9% of Pathogens SafelyAlcohol FreeHypoallergenicAloe Skin ConditionersVeterinarian Endorsed

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GRAS #1 2013

Intercepting the microbes that can hurt us, while leaving the other beneficial ones to do their jobs can be easily accomplished with a single wipe with a safe antibacterial wet cloth. PAWtizer contains benzalkonium сhloride, the active ingredient in Bactine and Benzocaine. A single wipe will eliminate 99.9% of the harmful bacterial on paws, face, coat and yourself safely for hours. As it contains no alcohol it won’t burn or dehy-drate and its hypoallergenic.

There are as many germs on paws as there are on hands. Pass it on.

“It only takes 10 microbes to give us a Salmonella, e.coli or MRSa infection...

and there are 78,500,000 Dogs”

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People and dogs alike carry a million microbes on their skin (and coat) and no two of us carry the same combination of them. Even though we bathe, those microbes will regenerate by themselves daily. A few microbes, both benign and dangerous will be picked up from objects, organic and inorganic surfaces, other people and other dogs. While 999,999 are harmless, it only takes 10 microbes to give us a salmonella, E.coli or MRSA infection. Curiously, those ten dangerous ones can be passed onto us from our dogs who innocently picked them up and gave them back to us.

and there are 78,500,000 Dogs”

TheRe aRe aS manY geRmS on PawS aS TheRe aRe on handS

TM

Available at

www.pawtizer.com www.allamericanpetcompany.com /pawtizer www.allamericanpetbrands.com

INTRODUCING THE ONLY 99.9% EFFECTIVE ANTIBACTERIAL SPRAY AND WIPE FOR DOGS

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GRAS Magazine | issue 1