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1 Gastritis: Causes Helicobacter pylori infection NSAID use Excessive alcohol consumption Heavy smoking Radiotherapy Cancer chemotherapy Systemic infections (Salmonella, CMV) Severe stress Ischemia and shock Suicide attempts with acids or alkali Mechanical trauma Distal gastrectomy

Gastritis: Causes - Columbia University in the City of … · 1 Gastritis: Causes • Helicobacter pylori infection • NSAID use • Excessive alcohol consumption • Heavy smoking

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Gastritis: Causes• Helicobacter pylori infection• NSAID use• Excessive alcohol consumption• Heavy smoking• Radiotherapy• Cancer chemotherapy• Systemic infections (Salmonella, CMV)• Severe stress• Ischemia and shock• Suicide attempts with acids or alkali• Mechanical trauma• Distal gastrectomy

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Types of Chronic Gastritis• Autoimmune gastritis (type A gastritis):

diffuse gastritis of corpus; antibodies to parietal cells andintrinsic factor; low acid, pernicious anemia; associatedwith other autoimmune disorders; uncommon.

• Helicobacter pylori gastritis (type B gastritis):may affect all parts of the stomach, mostly antrum; 3subtypes: antrum-predominant, corpus-predominant,pangastritis; very common.

• Chemical gastritis (type C gastritis): due torepeated chemical or toxic injury (bile acids, duodenalcontents, NSAIDs); common.

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Complications of H.pylorigastritis: Frequency

• Lymphoma: 0.1%

• Duodenal ulcer: 13%

• Carcinoma: 1%

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Gastric Polyps

• Hyperplastic polyp• Fundic gland polyp• Adenomatous polyp• Inflammatory fibroid polyp

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