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Function - Ephyla antiradical, antioxidant, vasoconstrictor Renewable botanical origin: Lannea microcarpa fruit extract Geographic origin: Intertropical West Africa (Burkina Faso)

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Page 1: Function - Ephyla antiradical, antioxidant, vasoconstrictor Renewable botanical origin: Lannea microcarpa fruit extract Geographic origin: Intertropical West Africa (Burkina Faso)
Page 2: Function - Ephyla antiradical, antioxidant, vasoconstrictor Renewable botanical origin: Lannea microcarpa fruit extract Geographic origin: Intertropical West Africa (Burkina Faso)

Function: antiradical, antioxidant, vasoconstrictor

Renewable botanical origin: Lannea microcarpa fruit extract

Geographic origin: Intertropical West Africa (Burkina Faso)

Cosmos, Ecocert standard availability

Available forms: Powder- Sensiteam Be- INCI: Bentonite & Lannea microcarpa fruit extract

Liquid - Sensiteam Et- INCI: Alcohol& Lannea microcarpa fruit extract

000

Identity card

an amazing Skin Protector Active Ingredient from African wild grape extract

EPHYLA SAS Centre De Recherche Yves Coppens, UBS - Campus de Tohannic BP 573 – 56000 Vannes Tel : 09.81.61.62.79 – Fax : 09.81.70.35.59 Email : [email protected]

In vivo analysis

1. Antiradical effect: DPPH Test

2. Antioxidant effect:

Results:

Lipoperoxidation particularly affects the lipid bilayers of cell membranes. Limit this stress contributes to maintain cell membranes integrity.

Sensiteam® reinforces cells membrane integrity at the basal level and ensures an anti-lipoperoxidation effect. 3. Vasoconstrictor effect

Efficiency of Sensiteam® at 1% on skin problem with a panel of 24 Canadians subjects versus placebo

In vitro analysis

Results:

Sensiteam® at 0,2 % : inhibition of 8 % of radical activity Sensiteam® at 2 % : inhibition of 100 % of radical activity

Because of the cellular senescence inhibition, SENSITEAM® extends

healthy life span of skin cells.

71,2 73,2

181,5

0

50

100

150

200

% E

ndot

hélin

s ne

oynt

hesi

s

Stimulation of endothelins neosynthesis-In vitro analysis of human endothelial cells

% SENSITEAM

50

55

60

65

70

75

80

85

J2 J7 J10

Num

ber o

f pos

itive

opi

nion

s (%

)

Fewer imperfections

SENSITEAM

Placebo

From 7 days, a high rate of satisfaction is expressed. The rate differs significantly from placebo effect.

Results:

By stimulating endothelins neosynthesis, Sensiteam® increases cellular regeneration of skin microvessels. Skin vascularization is improved and its unsightly disorders are cleared.

0,004% 0,01% 0,02%

-9 -64

-100 -200

-100

0

% T

BA

RS

% Sensiteam

Decrease in the basal emergence of TBARS - In vitro in a human dermal fibroblast model 0,002 % 0,01 % 0,02 %