DISCIPLINE: ENDOCRINE

Key points in anatomy and physiology Points essentiels en anatomie et en physiologie

Gland Les Glandes

Hypothalamus GnRH (Gonadotrophin Releasing Hormone), TRH (Thyrotropin Releasing Hormone), Dopamine, GHRH (Growth Hormone Releasing Hormone), Somatostatin, CRH (Corticotropin Releasing Hormone)

LHypothalamus GnRH (Gonadolibrine), TRH (Thyrolibrine), Dopamine, GHRH (Somatocrinine), Somatostatine, CRH (Corticolibrine)

Pituitary:

GH (Growth Hormone), TSH (Thyroid Stimulating Hormone), Prolactin, FSH (Follicle Stimulating Hormone), LH (Luteinizing Hormone), ACTH (Adrenocorticotrophic Hormone)

Posterior Pituitary Oxytocin, ADH (Antidiuretic Hormone) [Vasopressin]

LHypophyse :

LHypophyse antrieure GH (Hormone de croissance), TSH (Thyrotropine), Prolactine, Gonadotropines FSH (hormone folliculo-stimulante), LH( hormone de lutinisation), ACTH (corticotropine)

LHypophyse postrieure Ocytocine, ADH (Hormone antidiurtique, Vasopressine)

Thyroid - Thyroxine Thyrode Thyroxine

Parathyroid Parathyroid Hormone Parathyrodes Parathormone

Pancreas Insulin, Glucagon, Somatostatin Pancras Insuline Glucagon, Somatostatine

Adrenals Cortisol, Aldosterone, DHEA (Dihydroepiandosterone)

Surrnales:

Corticosurrnale :

o Glucocorticodes (Cortisol)

o Minralocortcodes (Aldostrone)

o Andrognes (Dhydropiandrostrone = DHEA, Androstnedione)

Mdullo-surrnale: Adrnaline, Noradrnaline, Dopamine

Gonads Gonades

Testes - Testosterone Testicules Testostrone

Ovaries Oestrogen, Progesterone Ovaires strognes, Progestrone

Autocrine Autocrine

Paracrine Parakrin

Endocrine Paracrine

Viatmin D Vitamine D

Noradrenaline (NA) Noradrnaline (NA)

Triiodothyronine Triodothyronine (T3), Ttraodothyronine

(Thyroxine, T4)

History Taking Anamnse

Major presentations of disease Prsentations principales (cliniques) des pathologies

Alopecia Alopcie

Amenorrhoea Amnorrhe

Angina Angor (angine de poitrine)

Ankle swelling Gonflement de cheville

Anorexia Anorexie

Anxiety Anxit

Apathy Apathie

Bruising Ecchymose

Carpal Tunnel Syndrome Syndrome du canal carpien

Cataracts Cataracte

Central Obesity Obsit centrale

Constipation Constipation

Deafness Surdit

Decreased Skin Thickness Atrophie cutane

Depression Dpression

Diarrhoea Diarrhe

Diplopia Diplopie

Dry Hair Cheveux secs

Dry Skin Peau sche

Excessive Lacrimation Larmoiement excessif

Fatigue Fatigue

Galactorrhoea Galactorrhe

Gynaecomastia Gyncomastie

Hair Thinning Perte de cheveux

Heat/Cold Intolerance Intolrance la chaleur/ au froid

Hypercalcaemia Hypercalcmie

Hyperglycaemia Hyperglycmie

Hyperkalaemia Hyperkalimie

Hypoglycaemia Hypoglycmie

Hyponatraemia Hyponatrmie

Impotence Impuissance

Infertility Infertilit

Irritability Irritabilit

Loss of libido Perte de la libido

Loss of secondary sexual characteristics Absence de caractres sexuels secondaires

Loss of visual acuity Perte de lacuit visuelle

Menorrhagia Mnorragie

Moon Face Visage lunaire

Muscle stiffness Rigidit musculaire

Muscle weakness Faiblesse musculaire (Asthnie musculaire / Myasthnie?)

Palpitations Palpitations

Peptic Ulceration Ulcre peptique (ulcre gastro-duodnal)

Pigmentation Pigmentation

Postural Hypotension Hypotension orthostatique

Primary/Secondary Amenorrhoea Amnorrhe primaire / secondaire

Pruritis Prurit

Psychosis Psychose

Renal Colic Colique nphrtique

Shock Choc

Steatorrhoea Statorrhe

Striae Vergetures

Sweating Transpiration/ Sudation

Tremor Tremor (tremblement)

Vomiting Vomissement

Weight loss/gain Perte/gain de poids

Retinopathy Rtinopathie

Nephropathy (Diabetic) Nphropathie (Nphropathie diabtique)

Peripheral Neuropathy Neuropathie priphrique

Diabetic Foot Disease Le pied diabtique

Differential Diagnosis common clinical conditions

Diagnostic diffrentiel Affections mdicales frquentes

Pituitary Hypophyse

Pituitary Adenoma Adnome hypophysaire

Pituitary Insufficiency (post trauma) Insuffisance hypophysaire (post traumatique)

Acromegaly Acromgalie

Craniopharyngioma Craniopharyngiome

SIADH (Syndrome of Inappropriate Anti-Diuretic Hormone release)

SIADH (Syndrome de scrtion inapproprie dhormone antidiurtique)

Diabetes Insipidus Diabte insipide

Parathyroid Parathyrodes

Primary Hyperparathyroidism Hyperparathyrodie primaire

Secondary Hyperparathyroidism Hyperparathyrodie secondaire

Tertiary Hyperparathyroidism Hyperparathyrodie tertiaire

Pseudohyperparathyroidism Pseudo-hyperparathyrodie

Thyroid Thyrode

Hypothyroidism Hypothyrodie

Hyperthyroidism Hyperthyrodie

Graves Disease Maladie de Graves-Basedow

Autoimmune Hypothyroidism Hypothyrodie auto-immune

Multinodular Goitre Goitre micronodulaire

Transient Thyroiditis Thyrodite transitoire

Thyrotoxic Crisis Crise thyrotoxique (thyrotoxicose ou thyrotoxicose)

Hashimotos Thyroiditis Thyrodite dHashimoto

Adrenals Surrnales

Phaeochromocytoma Phochromocytome

Congenital Adrenal Hyperplasia Hyperplasie congnitale des surrnales

Cushings Disease Maladie de Cushing (hypercortisme hypophysaire) Syndrome de Cushing (hypercortisme de toute cause confondue)

Addisons Disease Maladie dAddison (insuffisance surrnalienne primaire)

Conns Syndrome Syndrome de Conn (hyperaldostrisme primaire)

GI Tract Tractus gastro-intestinal

Insulinoma Insulinome

Gastrinoma Gastrinome

Type 1 Diabetes Mellitus Diabte de type 1

Type 2 Diabetes Mellitus Diabte de type 2

Pancreatic Carcinoma (Adno)Carcinome pancratique

Neuroendocrine Tumours Tumeur neuroendocrine

Carcinoid Tumours Tumeur carcinode

Reproductive Systme reproducteur :

PCOS (Polycystic Ovarian Syndrome) SOPK (Syndrome des ovaires polykystiques ou syndrome de Stein-Leventhal)

Leydig Cell Tumour Tumeur ( cellules) de Leydig

Teratoma Tratome

Granulosa Cell Tumour Tumeur cellules de la granuleuse

Menopause Mnopause

Hypogonadism Hypogonadisme

Turners Syndrome (45XO) Syndrome de Turner (45X0)

Klinefelters Syndrome (47XXY) Syndrome de Klinefelter (47XXY)

5 alpha reductase deficiency (guevedoce) Dficit en 5-alpha rductase (Guevedoces)

Investigations Examens complmentaires

Blood Glucose (BM) Glycmie

Calcium Calcium

CT CT scan (tomodensitomtrie)

Dexamethasone Suppression Test Test de suppression la dexamthasone

FNA Cytology Cytologie sur ponction laiguille fine

Gonadotropins Gonadotrophines

MRI IRM (Imagerie par Rsonance Magntique)

PET Pet-scan (tomographie par mission de positons TEP)

Radionuclide Radionuclides (Radioisotopes / Isotopes, scintigraphie)

Serum Cortisol Cortisol srique

Sinus ACTH Sampling Dosage dACTH au niveau des sinus

Specific Hormone Testing Tests hormonaux spcifiques

Thyroxine Thyroxine

TSH TSH

Ultrasound Echographie

Urinalysis Analyse durines