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Tumor Markers: Development and Use in Clinical OncologyRichard L. Schilsky and Sheila Taube, Guest Editors
June 2002
Introduction: Tumor Markers as Clinical Cancer Tests—Are We There Yet? Richard L. Schilsky andSheila Taube
Issues and Barriers to Development of Clinically Useful Tumor Markers:A Development Pathway Proposal M. Elizabeth H. Hammond and Sheila E. Taube
Issues in Clinical Trial Design for Tumor Marker Studies Daniel Sargent and Carmen Allegra
c-erbB-2 in Breast Cancer: Development of a Clinically Useful Marker Daniel F. Hayesand Ann D. Thor
P53 Gene Mutations: Case Study of a Clinical Marker for Solid Tumors Minetta C. Liu andEdward P. Gelmann
Clinical Translation of Gene Expression Profiling in Lymphomas and Leukemias Andreas Rosenwaldand Louis M. Staudt
Prostate-Specific Antigen in Prostate Cancer: A Case Study in the Development of a Tumor Markerto Monitor Recurrence and Assess Response Eric J. Small and Mack Roach III
Pathological and Molecular Assessment of Sentinal Lymph Nodes in Solid Tumors David Krag andDonald L. Weaver
Challenges in Developing a Molecular Characterization of Cancer Jonathan R. Pollack,Matt van de Rijn, and David Botstein
Doctor’s Dilemma: Incorporating Tumor Markers Into Clinical Decision-Making Christina M. Caniland Ian F. Tannock
Regulatory Issues in Tumor Marker Development Steven Gutman
Forthcoming Issue