Formation Constants From Several Sources

8/12/2019 Formation Constants From Several Sources

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Source: https://www.akzonobel.com/dissolvine/functions/the_right_chelate/

DTPA according to Martell

Ca2+ at 25C mu 0.1 = 10.75 (+-6)^91

DTPA combines more with Ca. Martell

Metal ion EDTA GLDA DTPA HEDTA NTA EDG PDTA

Al3+ 16.4 12.2* 18.6 14.4 11.4 7.7 16.3

Ba 2+ 7.9 3.5 8.7 6.2 4.8 3.4 3.9

Ca 2+ 10.7 5.9 10.8 8.1 6.4 4.7 7.2

Cd 2+ 16.5 9.1* 19.0 13.7 9.8 7.4 13.8

Co 2+ 16.5 10.0* 18.8 14.5 10.4 8.0 15.5

Cu 2+ 18.8 13.1 21.2 17.4 13.0 11.8 18.8

Fe 2+ 14.3 8.7* 16.2 12.2 8.9 6.8 13.4

Fe3+ 25.1 11.7* 28.0 19.7 15.9 11.6 21.6

Hg 2+ 21.5 14.3 26.4 20.1 14.3 5.5 19.8

Mg 2+ 8.8 5.2 9.3 7.0 5.5 3.4 6.2

Mn 2+ 13.9 7.6* 15.2 11.1 7.5 5.5 10.0

Ni2+ 18.4 10.9* 30.1 17.1 11.5 9.3 18.2

Pb 2+ 18.0 10.5* 18.8 15.6 11.5 9.4 13.6

Sr 2+ 8.7 4.1 9.8 6.8 5.0 3.8 5.2

Zn2+

16.5 10.0* 18.2 14.6 10.7 8.4 15.2


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STABILITY CONSTANTS OF LIGAND & METAL: Source: http://george-eby-research.com/html/stability_constants.html

Metal (to right)Ligand (below)

Al( I I I ) Ba Ca

Co(I I ) Cu

Fe(I I )

Fe(II I ) H g M g M n Ni Sr Zn

Acetic acid 0.39 0.53 2.24 3.7d 0.51 0.74 0.43 1.03

Adenine

Adipic acid 1.92 2.19 3.35

ADP 2.36 2.82 3.68 5.90 3.11 3.54 4.50 2.50 4.28

Alanine 0.80 1.24 4.82 8.18 3.24 5.96 0.73 5.16

-Alanine 7.13 4.63 4

Albumin 2.20

Arginine 3.20 2.0

Ascorbic acid 0.19 0.35Asparagine 0 0.43

Aspartic acid 1.14 1.16 5.90 8.57 2.43 3.74 7.12 1.48 5.842.90a

ATP 9.8 3.29 3.60 4.62 6.13 4.0 3.98 5.02 3.03 4.25

Benzoic acid 1.6 0.9 0.9n -Butyric acid 0.31 0.51 2.14 0.53 0.36 1.00

Casein 2.23

Citraconic acid 1.3 1.3

Citric acid 11.7e 2.3 3.5 4.4 6.1 3.2 11.8510.9d 2.8 3.2 4.8 2.8 4.5

Cysteine 9.3 19.2 6.2 14.4d < 4 4.1 10.4 9.8

Dehydracetic acid 5.6 4.1

Desferri-ferrichrysin 29.9Desferri-ferrichrome 29.0

Desferri-ferrioxamin E 11.8 13.7 32.5 12.2 12.0

3,4-Dihydroxybenzoicacid

3.71 7.96 12.79 5.67 7.22 8.27 8.91

Dimethylglyoxime 11.94 14.6 7.7

O,O -Dimethylpurpurogallin

4.5 6.6 9.2 4.9 6.7 6.8

DNA


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EDTA 16.13 7.7810.70

16.21 18.8 14.3 25.7

21.5d 8.69

13.56

18.56 8.63 16.5

Formic acid 0.60 0.80 1.98 3.1 0.66 0.60

Fumaric acid 1.59 2.00 2.51 0.99 0.54

Globulin 2.32

Gluconic acid 0.95 1.21 18.29 0.70 1.00 1.70

Glutamic acid 1.28 1.43 5.06 7.85 4.6 1.9 3.3 5.9 1.37 5.45Glutaric acid 2.04 1.06 2.4 1.08 0.6 1.60

Glyceric acid 0.80 b1.18

b0.86

b0.89

b 1.80b

Glycine 0.77 1.43 5.23 8.22 4.3 10.0 10.3

d3.45 3.2 6.1 0.91 5.16

Glycolic acid 0.66 1.11 1.60 2.81 4.7 0.92 b0.80

b 1.92b

Glycylglycine 1.24 3.00 6.7 2.62 9.1 1.34 2.19 4.18 3.91

Glycylsarcosine 3.91 6.50 2.29 4.44Guanosine 3.2 6 4.3 3.0 3.8 4.6

Histamine 5.16 9.55 9.60 3.72 6.88 5.96

Histidine 7.30 10.60 5.89 4.00 3.58 8.69 6.63

-Hydroxybutyric0.43

b0.60

b0.60

b0.47

b 1.06b

3-Hydroxyflavone 9.91 13.20 9.70

Inosine 2.6 5 3 3.3

Inosine triphosphate 3.76 4.74 4.04 4.57

Iron-free ferrichrome 24.6

Isovaleric acid 0.20 2.08

Itaconic acid 1.20 2.8 1.8 0.96 1.9

Kojic acid 7.7 2.5 7.11 6.6 9.2 3.0 7.4 4.9

Lactic acid 0.55 1.07 1.89 3.02 6.4 0.93 1.19 2.21 0.70 1.86

Leucine 4.49 7.0 3.42 9.9 2.15 5.58 4.92

Lysine 4.5 2.18

Maleic acid 2.26 2.43 3.90 1.68 2.0 1.1 2.0

Malic acid 1.30 1.80 3.4 1.55 2.24 1.45 2.80Methionine 3.24 9.1 5.77 4.38


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Methylsalicylate 5.90 9.77

NTA >10 4.82 6.41 10.6 12.68 8.84 15.87 5.41 7.4411.26 4.98 10.45

Metal (to right)Ligand (below)

Al( I I I ) Ba Ca

Co(I I ) Cu

Fe(I I )

Fe(II I ) H g M g M n Ni Sr Zn

Orotic acid 6.39c 6.82c 6.42c

Ornithine 4.02 6.90 3.09 8.7 4.7 9.4 2.55 3.9 5.16 2.54 4.9

-Phenylalanine 7.74 3.26 8.9

Pimelic acid 1.08

Pivalic acid 0.55 2.19Polyphosphate 3.0 3.5 3.0 3.2 5.5 3.0 2.5Proline 4.07 10.0 3.34

Propionic acid 0.34 0.50 2.2 3.45 0.54 0.43 1.01

Purine 6.90 4.88

Pyrophosphate 5.0 6.7 22.2 5.7 5.8 8.7

Pyruvic acid 0.8 2.2

Riboflavin 3.9


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n -Valeric acid 0.20 0.30 2.12

Valine 7.92 3.39 9.6 2.84 5.37 5.0

Xanthosine 2.8 3.4


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Formation Constants From Several Sources