florence prigent, md, bs, facc, fasnc

February, 2010

__________________________________ Signature

FLORENCE PRIGENT, M.D., B.S., F.A.C.C., F.A.S.N.C.

OFFICE ADDRESS: Harper University Hospital Academic Cardiology (Hudson 4, # 4906) 3990 John R Detroit, MI 48201 Phone: (313) 745‐2647 Fax: (313) 745‐8643 E‐mail: [email protected] EDUCATION: 1968‐1970 Bachelor in Sciences, Lycee de Lillebonne, France 1970‐1977 Medical School, Rouen University School of Medicine, Rouen, France POSTGRADUATE TRAINING: 1977‐1981 Residency and Cardiology Fellowship, Rouen University Hospital, France.

Medicine, Intensive Care and Cardiology 1981‐1982 Clinical Cardiology Fellow, Cedars Sinai Medical Center, Los Angeles, CA.

Cardiovascular Surgery Intensive Care 1982‐1985 Cardiology Fellow, Cedars Sinai Medical Center, Los Angeles. (American Heart

Association Fellow, Nuclear Cardiology) 1985‐1986 Rotating Internship and Senior Resident, Veterans Administration Medical

Center, Sepulveda, CA, Nuclear Medicine and Medicine 1987 Sabbatical Training at the National Heart and Chest Institute, Cardiac MRI Unit,

London, UK, for 3 weeks 2005‐2009 Training in Cardiac Computed Tomography Angiography (CCTA) to become level

II, then level III credentialed by the Society of Cardiac Computed Tomography.

Florence Prigent, MD

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FACULTY APPOINTMENTS:

1986‐1988 Assistant Professor of Radiology, University of Miami School of Medicine,

Miami, FL 1988‐1990 Assistant Professor of Radiology, UCLA School of Medicine, Los Angeles, CA 2001‐2005 Associate Professor of Medicine, Health Sciences Center, State University of

New York at Stony Brook, Long Island, NY 2004‐Present Associate Professor of Medicine, Wayne State University, Clinical Educator Track HOSPITAL OR OTHER PROFESSIONAL APPOINTMENTS: 1986‐1988 Director, Nuclear Cardiology, University of Miami School of Medicine 1986‐1988 Physician‐in‐Charge, Cardiac Magnetic Resonance Imaging, University of Miami,

School of Medicine, Miami, FL 1986‐1988 Nuclear Medicine Physician, Division of Nuclear Medicine, Department of

Radiology, University of Miami, Jackson Memorial Hospital and University of Miami Hospitals at NCCH, Miami, FL

1986‐1988 Nuclear Medicine Physician, Division of Nuclear Medicine, Cedars Medical

Center, Miami, FL 1998‐1990 Associate Nuclear Cardiologist and Nuclear Medicine Physician: Cedars Sinai

Medical Center and Out‐patient Center (Cardiac & Vascular Diagnostic Center), Los Angeles, CA

1988‐1990 Research Consultant, Nuclear Cardiology: Cedars Sinai Medical Center, Los

Angeles, CA 1990‐1992 Associate Director Nuclear Cardiology, Division of Cardiology, St.

Luke’s/Roosevelt Medical Center, New York, New York 1990‐1992 Physician‐in‐Charge, Cardio‐Diagnostic Center, New York, NY 1990‐1993 St. Luke’s Roosevelt Medical Center, New York, NY 1994‐2003 Co‐Director, Nuclear Cardiology, Division of Cardiology, Winthrop‐University

Hospital, and Winthrop Cardiology Associates, Minneola, NY 2004‐Present Director, Nuclear Cardiology, Wayne State University


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2004‐2009 Director, Nuclear Cardiology and Cardiac Stress Laboratory, Harper University Hospital and Wayne State University School of Medicine, Detroit, MI. (Voluntary resignation in 2009)

2005‐present Teaching Faculty, Nuclear Cardiology, Division of Cardiology, St. John Hospital

(affiliated WSU teaching program). 2006‐present Cardiac PET Imaging, Children’s Hospital, DMC, Detroit, MI 2009‐present Chief, Nuclear Cardiology and Cardiac Stress Laboratory, John D. Dingell VA

Hospital 2009‐present Acting Radiation Safety Officer, JDVA MAJOR PROFESSIONAL SOCIETIES: 1985‐1992 *American Association of Nuclear Physicians 1985‐2009 *Society of Nuclear Medicine, with membership in the Cardiovascular & PET

Councils 1986‐1992 *Society of Magnetic Resonance in Medicine 1986‐1992 *American Federation for Clinical Research 1986‐2000 *American Heart Association with membership in the Cardiovascular Radiology

and Clinical Cardiology Council 1993‐present American Society for Nuclear Cardiology – Full Member 1995‐1999 *American Association for Nuclear Cardiology‐Full Member 1996‐1998 *Heart Failure Society of America 1996‐2000 *American Medical Association, Nassau County Academic Society, Nassau

County Medical Society 1999‐2000 *International Society of Holter and Non‐Invasive Cardiology 1999‐2001 *Society of Geriatric Cardiology 2000‐2003 *Elected Fellow of the American College of Chest Physicians 2000‐present Elected, Fellow American College of Cardiology 2005‐present Founding Member Society of Cardiac Computed Tomography (SCCT)


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2006‐present Elected, Fellow American society of Nuclear Cardiology 2009‐present American Heart Association *Membership not renewed for cost containment. MEDICAL LICENSURE: 1981‐present French Medical License 1986‐2007 Florida State Medical License, I voluntarily relinquished my license for cost

containment. 1988‐2007 California State Medical License, I voluntarily relinquished my license for cost

containment 1994‐2003 Listed as an authorized user on NYS DOH Radioactive License 1990‐present New York State Medical License 2004‐present Michigan Board of Medicine License 2004‐present Michigan Pharmacy Controlled Substance License 1986‐present DEA 2004‐present Listed as Authorized user, Harper University Hospital Radionuclide License 2006‐present Listed as authorized user on nuclear license, Pet Imaging Center, Children’s

Hospital of Michigan, DMC, Detroit, MI: 2009‐present Listed as authorized user on nuclear license JDVA BOARD CERTIFICATION: 1970 Baccalaureate in Sciences (Mathematics & Physics) with Honors, National

Examination France. 1977 Passed Competitive Examination for the entrance into the four year Residency/

Fellowship Program at Rouen University Hospitals (Concours de l’Internat, which is the highest distinction in medical training in France)

1981 Doctor in Medicine, Rouen University School of Medicine, Rouen, France 1981 French Cardiology Boards (valid indefinitely)


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1981 California FLEX 1982 ECFMG 1987 American Board of Nuclear Medicine (valid indefinitely) 1996 Certification Examination in Nuclear Cardiology, American Society of Nuclear

Cardiology (valid indefinitely) 2009 Recertification in BCLS 2007, 2010 Recertification ACLS 2008 Cardiac CT Level II: credentialed by the Society of Cardiac Computed

Tomography, verification valid until 2011 2009 Cardiac CT Level III: credentialed by the Society of Cardiac Computed

Tomography, verification valid until 2012 2009 Passes Certification Board in Cardio‐vascular Computed Tomography, valid until

2019 HONORS/AWARDS: 1963‐1970 Best student throughout Junior High School and High School. 1974 Selected among Rouen University medical Students for ten weeks medical

training in USA (Albany University School of Medicine, NY). 1977 Passed the Competitive Examination for the entrance into a four year Residency

Fellowship program in Rouen University Hospitals (“Concours de l’Internat” which is the highest distinction in medical training in France).

1983‐1985 American Heart Association Fellow; Greater Los Angeles Affiliated Chapter,

Division of Nuclear Cardiology, Cedars‐Sinai Medical Center 1984 Young Investigator Competition Finalist, American Heart Association, Los

Angeles Affiliate 1985 Young Investigator Competition Finalist, American Heart Association, Los

Angeles Affiliate 1987 Sabbatical training at the National Heart and Chest Institute MRI Unit, London,

UK 1989 Young Investigator Competition Finalist, American heart Association, Greater

Los Angeles Affiliate


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1989 Young Investigator Competition Finalist, Society of Nuclear Medicine National

Meeting 1990 Young Investigator competition Finalist, American Heart Association, Greater

Los Angeles Affiliate 1997 Winner, 1996 American Society of Nuclear Cardiology working groups

Membership Drive Contest, while I was the director of the Greater NY‐ long Island working group

1997 Best Cardiology Division, Winthrop University Hospital: US News and World

Reports, 1997 1998, 1991 Winthrop University Hospital was granted JCAHO Accreditation with

commendation 1999 Winner, Winthrop‐University Hospital Intramural Funding Competition 1999 Winner, Third Place Award at the Society of Geriatric Cardiology Open Division

Abstract Competition. National Meeting, New Orleans, LA, March 1999 2007 Nominated for WSU President Teaching Award (I did not pursue this project,

thinking it was for faculty on the Tenure Track) 2009 Nominated for Wayne State University College Teaching Award 2009 Awarded Wayne State University College Teaching Award


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SERVICE: Wayne State Departmental of Medicine/Division of Cardiology: (hire date 3/22/2004) 2005‐present Interview Cardiology Fellow’s Candidates every year

I interviewed 37 candidates in 2008, 18 candidates in 2009 Participate in fellow’s selection meetings School of medicine

2005‐2006 Grant Reviewer, Intra‐mural funding program, WSU: reviewed several proposals

2006‐present Member Research Steering Committee, WSU

University Physician group (hire date 3/22/2004)

2004‐2009 FTE 1.0.

Harper Hospital: Director of the Nuclear Cardiology and Stress testing Laboratory; Daily supervision, interpretation of stress tests and nuclear cardiology studies (average 8 hours a day).

Administrative responsibilities for the laboratory

Rest Electrocardiograms

Multiples in‐services / lectures for Harper Nuclear Cardiology technologists, nurses and physician assistant. Trained physician assistant and nurses to independently supervise stress testing

Interviewed all applicants for staff position (nurse, PA, technologist, ECG tech)

Didactic lectures to staff and new physician assistant

Met with vendors (radiopharmaceuticals, new stress testing agent)

Met with vendors and went on site visit to identify best potential camera for the laboratory in 2008

2007‐2009 Developed T wave alternans testing in the Harper stress laboratory: administration,

review of literature, in‐service to staff. Our Clinical program is now in place. 2005‐present Member Radiation Safety Committee, Harper Hospital 2009‐present In 2009, I voluntary resigned from my position of Director of Nuclear Cardiology at

Harper Hospital, so I could dedicate my time to my new position of Chief, Nuclear Cardiology at the Detroit VA. I am now part time at UPG, and my clinical activities at UPG include stress testing supervision and interpretation of stress tests, nuclear cardiology studies and ECG at Harper Hospital.


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Cardiac Pet Imaging/ Children’s Hospital

2006‐present Cardiac PET at Children’s Hospital: Developed Imaging protocols for the new PET‐CT

Scanner for Cardiac Perfusion imaging using N13 ammonia, Cardiac Sarcoidosis Imaging and Viability studies using F‐18 FDG glucose; Trained staffed for stress testing; Performance of several volunteer studies. I met with vendors for purchase of cardiac PET software. Our Clinical program is now running.

Detroit JD VA 2009‐present John Dingell VA Hospital (.5 FTE)

Chief of the Nuclear Cardiology and Stress Testing Laboratory Supervision, interpretation of stress tests and nuclear cardiology studies Rest ECG’s interpretation Administrative responsibilities In‐services/lectures to JDVA Nuclear Cardiologists, stress lab physician assistants, Nurse practitioners and ECG techs Review/development of all policies and protocols Member Radiation Safety Committee

Other Practice Plans: (prior to 2004) 1986‐1988 University Miami School of Medicine, Miami, Florida: Read nuclear medicine

scans (adults and pediatrics) at Jefferson Memorial Hospital, NCCH, and Cedars Hospital of Miami; Supervised stress testing at Cedars and NCCH; Administrative responsibilities; Developed Cardiac MRI program and read cardiac MRI scans at JMH; Daily clinical responsibilities. Radiation Safety Committee, JMH.

1988‐1990 Cedars Sinai Medical Center and outpatient nuclear cardiology laboratory:

supervision and interpretation of stress testing and interpretation of nuclear cardiology scans at outpatient center. Took night calls in nuclear medicine at CSMC.

1990‐1992 St. Luke’s/ Roosevelt Medical Center: Physician in charge, Diagnostic Outpatient

Cardiology Center: supervised and interpreted stress test and interpreted nuclear cardiology studies; Administrative responsibilities.

1994‐2003 Winthrop University Hospital: Co‐directed the Nuclear Cardiology Laboratories

at Winthrop University Hospital and Winthrop Cardiology Associates; Supervision and Interpretation of stress tests; Nuclear cardiology scans interpretation; Supervision of cardiac rehabilitation sessions. Radiation Safety Committee WUH from 1994‐2003; Credentialing Committee, WUH, 2001‐2003 (committee dissolved in fall of 2001); Member Investigational Review Board, 1996‐2003.


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Consulting: 1990 Lecturer Investigator Meeting on Antimyosin Antibodies, Rancho Las Palmas, CA 1996 Consultant for Davis/HRA Research: Future Trends in the Practice of Cardiology 1996‐present Lecturer for Fujisawa/Astellas Inc 2001‐2002 Expert Witness on a legal case involving a Myocardial Perfusion Scan 2003‐present Speaker Bureau, BMS Imaging Scholarly Services: Peer Review Journals 1985‐present Editorial consultant: American Heart Journal, American Journal of Cardiology,

Journal of the American College of Cardiology, Journal of Nuclear Medicine, Journal of the American Medical Association.

Abstract Reviewer 1987 Abstract Reviewer, Southeastern Chapter of the Society of Nuclear Medicine 1988 Abstract Reviewer, ACNP, Annual Meeting 1998 Abstract Reviewer, 1999 Scientific Sessions of the American College of

Cardiology 2000 Abstract Reviewer: 5th International Convention of Nuclear Cardiology 2007 Abstract reviewer, Cardiology Imaging Section, Society of Nuclear Medicine

Annual Meeting, June 2007 2009 Abstract reviewer, Cardiology Imaging Section, Society of Nuclear Medicine

Annual Meeting, June 2009 Question Writer for American Boards of Nuclear Cardiology 1997 Question Writer, Certification Boards in Nuclear Cardiology 1998 Question Writer, Certification Boards in Nuclear Cardiology 1999 Question Writer, Certification Boards in Nuclear Cardiology 2000 Question Writer, Certification Boards in Nuclear Cardiology


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2001 Question Writer, Certification Boards in Nuclear Cardiology 2002 Question Writer, Certification Boards in Nuclear Cardiology 2003 Question Writer, Certification Boards in Nuclear Cardiology 2004 Question Writer, Certification Boards in Nuclear Cardiology 2006 Question Writer, Certification Boards in Nuclear Cardiology 2007 Question Writer, Certification Boards in Nuclear Cardiology 2008 Question Writer, Certification Boards in Nuclear Cardiology 2009 Question Writer, Certification Boards in Nuclear Cardiology Investigational Review Board 1996‐2003 Member, Investigational Review Board Committee, Winthrop University

Hospital Medical Societies Committees/ Activities: 1987 Program Committee, Southeastern Chapter of the Society of Nuclear Medicine 1995‐2003 Founder and Director, American Society of Nuclear Cardiology ‘Greater New

York‐Long Island working group 1997‐2002 American Society of Nuclear Cardiology, Working Group Committee member 1997‐2002 American Society of Nuclear Cardiology, Membership Committee member 1998‐2001 American Society of Nuclear Cardiology, Corporate Sponsorship Committee

member 1999 Practice Expense Consensus Group on CPT code 78465 (American Society of

Nuclear Cardiology) 2004‐2005 President elect American society of Nuclear Cardiology, Michigan Chapter 2005 Committee CPT Coding Task Force of the American society of Nuclear Cardiology 2005 Organizing Committee, American Society of Nuclear Cardiology Annual Meeting,

Michigan Chapter: “Nuclear Cardiology as a Screening Tool”


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2005 Organizing Committee, American Society of Nuclear Cardiology Annual Meeting, Annual Fellows Competition, Michigan Chapter

2005‐2006 President, American Society of Nuclear Cardiology, Michigan Chapter 2006 CBNC Nuclear Cardiology Practice Analysis Survey. 2007 Society Cardiac Computed Coronary Angiography: Survey to determine task and

knowledge that physician must master in order to perform and interpret Cardiac CT examination in a comprehensive manner

Moderator for Scientific Sessions: 1987: Southern Chapter of the Society of Nuclear Medicine: Moderator, Cardiac Imaging. 1996: Chair, Case Review with the Experts Presentation; Symposium on Nuclear Cardiology:

American Society of Nuclear Cardiology, Greater New York/Long Island Working Group. Cold Spring Harbor Laboratory, Cold Spring Harbor, NY

1997: Chair, Case review with the expert session; Symposium on Myocardial Viability;

American Society of Nuclear Cardiology, Greater New York/Long Island Working Group, Cold Spring Harbor Laboratory, Cold Spring Harbor, NY

1998: Chair, Case review with the expert’s session; Symposium, Combined North Eastern

working groups of the American Society of Nuclear cardiology; New York, NY 1999: Co‐Chair, Original Contributions Session: American College of Cardiology Scientific

Sessions (Prognostic Impact of Cardiac Function and Perfusion) 2001: Chair: Essential Cardiology for the Nuclear Physician: Coronary Blood Flow in Health and

Disease; 5th International Convention for Nuclear Cardiology, Vienna Austria.

2001: Chair, original contribution sessions (Instrumentation), 5th International Convention for

Nuclear Cardiology, Vienna, Austria

2002: Chair, Advancements in Nuclear Cardiology; Combined Northeast ASNC Working Groups Meeting, New York, NY

2002: Chair, Update on Non‐gamma camera technologies, Combined Northeast ASNC Working

Groups Meeting. New York, NY 2005: Chair, New frontiers in cardiology, Imaging section; Symposium organized by WSU DMC;

Dearborn, MI


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TEACHING: Wayne State University: 2004‐present Director, Nuclear Cardiology, Wayne State University School of Medicine,

Detroit, Michigan Other Universities 1986‐1988 University of Miami, School of Medicine, Miami Florida 1988‐1990 UCLA, Los Angeles, California 1990‐1992 Columbia University College of Physicians and Surgeons, New York, New York 1994‐2003 SUNY Stony Brook, Minneola, New York Teaching at Wayne State University, School of Medicine:

WSU Internal Medicine Grand Rounds: 5/2007 PET Cardiac Hybrid Imaging 5/2009 Myocardial perfusion Imaging: the present and the future: implications for

fellows training in multi‐modality Imaging

Program Director, Nuclear Cardiology to WSU‐DMC Cardiology Fellows (12):

2004‐Present Clinical Rotations: Harper Hospital stress lab: Each Cardiology Fellow rotates for 4‐5 months in the nuclear laboratory; Training in stress testing; Daily didactic supervision of stress testing and reading sessions in nuclear cardiology and stress testing’ ECG’s for 8 hours daily. Since 2009, I also interpret studies at JDVA, so my clinical involvement at the Harper stress lab has decreased in proportion while the teaching curriculum has remained the same.

Until 2007 (enrollment completed), fellows had the opportunity to participate in

gas‐exchange stress testing (maximal 02 consumption analysis) at the Applebaum exercise physiology laboratory, as part of a National Institute of Health (NIH) grant (Exercise and Sleep Study).

2005‐2008 Nuclear Cardiology Course to Cardiology Fellows (12 fellows), St. John’s

Hospital, Detroit (WSU teaching affiliate): Each St John’s fellow rotated through the Harper Nuclear Cardiology program for approximately 1 month; their activities in the lab were the same as for the Harper fellows. In 2008, St. John’s


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Hospital was required to develop their own nuclear cardiology program and St. John fellows no longer rotate at the Harper Stress Lab.

2005‐present I am part of the St. John’s teaching faculty since November 2005 and I lecture

every month at St. John’s Hospital on Nuclear Cardiology Imaging, Cardiac PET Imaging and Stress Testing.

2006‐2009 Course to WSU Internal Medicine Residents: “Radionuclide Assessment of

Coronary Artery Disease: Audience includes residents, interns, and medical students. Due to time constraints, I had to stop this course

2007‐present Cardiology fellows supervise and interpret Cardiac PET Imaging studies as part

of the nuclear cardiology rotation. 2007‐present Cardiology fellows supervise and interpret T wave Alternans testing as part of

the nuclear cardiology rotation.

Course or Curriculum Development: WSU 2004‐present developed and updated on a yearly basis the nuclear cardiology teaching

curriculum WSU‐UPG fellowship program 2005‐present developed and yearly updated the nuclear cardiology teaching curriculum WSU‐

St ‐John fellowship program 2006‐present developed and yearly updated the cardiac PET teaching curriculum 2009‐present developed Curriculum for Non Invasive cardiac CT. The plan is to develop an

integrative non‐invasive imaging cardiology teaching curriculum that encompasses nuclear cardiology, cardiac PET, CMR, and CCTA to reflect current COCATS recommendation. Rotations will be split between the VA Hospital, the office of a private cardiologist that owns a CT scanner and DMC. There will be a yearly calendar of lectures to encompass all basic and clinical aspects of these techniques. Fellows will be prepared to sit for the CCTA boards in addition to the nuclear cardiology Boards. Radiology residents want to attend the lectures.

Academic Administration 2004‐Present: I am the dedicated Preceptor for all Harper/WSU fellows for all matters

regarding nuclear cardiology and cardiac Pet imaging Monthly feed‐back / evaluations of fellows during their rotations in the nuclear

lab Write / sign Preceptor certificate for Federal Nuclear Regulatory Commission

Write / Sign Letter so fellows can sit at the Certification boards of nuclear cardiology examination


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Critical review of physics Course which is given by a non‐WSU Physicist: for instance, in 2009, it appeared that the physic’s course need improvement and therefore that preceptor in physic’s had to be replaced. Arrangements have been made with Mr. Kumpuris, M.S. to teach the physic’s course in 2010. Reviewed physics curriculum with physicist; made sure NRC and CBNC physic’s / Radiation Safety educational requirements are met.

Stress Testing / Nuclear Cardiology Laboratory Precepting: 1 to 2 fellows rotate at a time per month, on average 8 hrs a day

Pre test patient examination, review of indications, contraindication and appropriateness of stress

testing and myocardial perfusion imaging. Supervision of fellows during stress testing; teaching skills for

ECG's and myocardial Perfusion Imaging interpretation; review of fellows preliminary interpretation

when they are advanced enough to do it; basic principles of physics, data acquisition, processing and

radiation safety.

On my reading days, I take fellows at the end of the day to the PET center to review any cardiac PET

(viability study or rest stress Perfusion) that would have been acquired

The rotating fellow in nuclear cardiology attend the in‐services to the staff in the stress lab.

Didactic lectures to WSU Fellows Harper University Hospital: One‐hour lectures were given to fellows and some faculty, residents, and medical students by Dr Prigent 04/2004 Principles of SPECT Interpretation 05/2004 Artifacts in SPECT Imaging 6/2004 Radionuclide Assessment of Myocardial Viability 7/2004 Stress testing in nuclear cardiology 10/2004 Cases Presentations; myocardial perfusion SPECT quantification 11/2004 Case Presentation 12/2004 Case Presentation 3/2005 Radiopharmaceuticals and Imaging protocols in Nuclear Cardiology 4/2005 Case Presentation 5/2005 SPECT Quantification / Bull’s eyes


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7/2005 Stress testing in the nuclear cardiology laboratory, 1 8/2005 Stress testing in the Nuclear Cardiology Laboratory, 2 9/2005 Case Presentations 10/2005 On‐going research in the Harper Nuclear Cardiology Laboratory 12/2005 Nuclear Cardiology Case Studies 2/2006 Cases 3/2006 Case Presentation 5/2006 Nuclear Cardiology Board Review 1 6/2006 Nuclear Cardiology Board Review 2 7/2006 Lecture: Introduction to stress testing 8/2006 Lecture: Stress Testing 2 10/2006 Case Presentation 11/2006 Quality Control of Gamma Cameras 12/2006 Case Presentation 1/2007 Case Presentation 2/2007 Myocardial Viability 3/2007 Quantification in myocardial perfusion Imaging 6/2007 Helped Dr. Jin to prepare and present a lecture on radionuclide

ventriculography 7/2007 Introduction to stress testing 1 8/2007 Introduction to stress testing 2 10/2007 Myocardial Perfusion Imaging Interpretation 1 11/9/207 Nuclear Cardiology Case Review 11/30/207 Nuclear Cardiology Review boards 12/2007 Interpretation of Myocardial perfusion imaging cases


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2/2008 Helped Dr. Mohammad prepare and present lecture on physiology of coronary

blood flow 3/2008 Case Presentation 4/2008 Helped Dr. Mohammad finish lecture on physiology of coronary blood flow 5/2008 Nuclear Cardiology Board Review, 1 6/2008 Nuclear Cardiology Board Review, 2 7/2008 Introduction to Stress Testing, 1 8/2008 Introduction to Stress Testing, 2 8/2008 Introduction to Stress Testing, 3: Introduction Cardiac PET Imaging 9/2008 Interpretation of Perfusion Scan, 1 10/2008 Interpretation of Perfusion Scan, 2 10/2008 Interpretation of Perfusion Scan, 3 10/2008 Moderator MRI Self assessment Program 11/2008 Nuclear Cardiology Board Review, 1 11/2008 Nuclear Cardiology Board Review, 2 12/2008 Case Presentation, 1 12/2008 Case Presentation, 2 1/16/2009 Case presentation 2/23/2009 Radio‐pharmaceuticals and Protocols 3/5/2009 Moderator during fellow lecture on Stress Testing 3/11/2009 Helped fellow to prepare and give presentation on myocardial Viability 3/18/2009 Moderator during Journal Club presentation 4/22/2009 Nuclear Imaging: interpretation 4/23/2009 Moderator during Journal Club presentation on Courage trial


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6/4/2009 Nuclear board review/Nuke Sap 6/8/2009 Nuclear board review/Nuke Sap 6/11/2009 Nuclear board review/Nuke Sap 6/12/2009 Nuclear board review/Nuke Sap 6/24/2009 Nuclear board review/Nuke Sap 7/6/2009 Introduction to Stress Testing 1 7/7/2009 Moderated an In‐service on New stress testing agent to nuclear cardiology

fellows and stress testing Staff, Harper hospital 7/9/2009 Introduction to Stress Testing 2 7/23/2009 CCTA 1 Anatomy scanner 8/17/2009 Helped fellow to prepare and present AHA/ACC/ASNC guidelines for pre‐

operative assessment 8/20/2009 Introduction to Stress Testing 3 8/24/2009 Helped fellow prepare and present lecture on Appropriateness Criteria for

nuclear Perfusion Imaging 8/26/2009 Organizer & Moderator during Radiation Safety lecture given by Mr. Kumpuris,

physicist 8/27/2009 Cardiac Imaging protocols 1 9/10/2009 Nuclear board review/Basic sciences 9/16/2009 Nuclear board review/basic sciences 9/23/2009 Organizer Moderator during “NRC Physician requirements” lecture by Mr.

Kumpuris, physicist 9/30/2009 ECG basic interpretation 10/5/2009 Nuclear board review/basic sciences 10/7/2009 Nuclear board review/basic sciences 10/21/2009 Nuclear board review/basic sciences 10/22/2009 Nuclear board review/basic sciences


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11/5/2009 Cardiac Imaging: Interpretation myocardial Perfusion Images 11/9/2009 Cardiac Imaging; Interpretation myocardial Perfusion Images 11/18/2009 Organizer and Moderator during lecture on “Requirements to be a radiation

Safety Officer” by Mr. Kumpuris, physicist 11/25/2009 Cardiac Imaging: Nuclear Board Review misc. 11/30/2009 Cardiac Imaging: Nuclear Board Review misc. Of Note, at the request of cardiology fellows, I volunteered several times to give the noon lecture when

no other faculty member was able to do it.

Lectures to WSU Cardiology Fellows at St. John Hospital: 11/2005 Case Presentation with Emphasis on SPECT Interpretation 12/2005 Case Presentation with Emphasis on SPECT Artifacts 01/2006 Radio Pharmaceuticals and Protocols 3/2006 Nuclear Cardiology Board Review, 1 4/2006 Nuclear Cardiology Board Review, 2 6/2006 Case Presentation 7/2006 Introduction to Stress Testing, 1 8/2006 Introduction to Stress Testing, 2 10/2006 Case Presentation, 1 10/2006 Case Presentation, 2 12/2006 Case Presentation 2/2007 Myocardial Viability 3/2007 Quantification in Myocardial Perfusion Imaging 6/2007 Cardiac PET Hybrid Imaging 7/2007 Introduction to Stress Testing, 1


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8/2007 Introduction to Stress Testing, 2 10/2007 Interpretation of Myocardial Perfusion Imaging 1 10/2007 Interpretation of Myocardial Perfusion Imaging 2 11/2007 Nuclear Cardiology Board Review Course 12/2007 Nuclear Cardiology Cases 1/2008 Nuclear Cardiology Case and Attenuation correction 2/2008 Case/Pre‐test Likelihood, Localization Scheme 4/2008 Case Presentation, 1 4/2008 Case Presentation, 2 5/2008 Nuclear Cardiology Board Review 8/2008 Stress Testing 1 9/2008 Stress Testing 2 10/2008 Nuclear Cardiology Board Review Course 11/2008 Interpretation of Myocardial Perfusion Scan 1 12/2008 Interpretation of Myocardial Perfusion Scan 2 1/16/2009: Case presentation 2/20/2009: Imaging Protocols 4/20/2009 Myocardial Viability 5/29/2009 Myocardial perfusion Imaging: the present and the future: implications for

fellows training in multi‐modality Imaging 8/25/2009 Introduction to Stress testing 10/27/2009 Q&A Basic Nukes, and myocardial viability, part 2 The Nuclear Cardiology Course described above is intended to prepare the fellows for the certification Board of Nuclear Cardiology. I do all of the nuclear cardiology teaching. This course has resulted in 100% success rate at the Certification Boards in Nuclear Cardiology for cardiology fellows in 2006, 2007, 2008 and 2009 for both Harper and St. John’s. Successful candidates are:


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2006 Harper: Drs. Reddy, Dawson, Modi (3 candidates) 2006 St. John’s: Drs. Adulmalik and Basit (2 candidates) 2007 Harper: Drs. Ramappa, Jin, Pitta, Bachour, Bernal, Ali, Rudriah (7 candidates) 2007 St. John’s: Drs. Jefic, Aboufakher, Ganthok, Kamal, Basit, Desai (6 candidates) 2008 Harper: Drs. Kizilbash, Khetarpal (2 candidates) 2008 St. John’s: Drs. Koul, Boguszewski, Franck, Alroaini (4 candidates) 2009 Harper: Drs Kottam, Pradhan, Sigmen, Mohammad (4 candidates) 2009 St. John’s: Manreet Kanwar, Jigishu Dhabuwala, Dennis Doan, Jay Hamze (4

candidates)

Didactic lectures to WSU Internal Medicine residents One hour lectures to WSU Internal Medicine Residents, Interns, and Medical Students, Harper University Hospital Jan. 11, 2006 Radionuclide assessment of coronary artery disease, 1 Jan. 18, 2006 Radionuclide assessment of coronary artery disease, 2 Feb. 8, 2006 Radionuclide assessment of coronary artery disease, 1 Feb. 15, 2006 Radionuclide assessment of coronary artery disease, 2 Feb. 22, 2006 Radionuclide assessment of coronary artery disease, 3 Mar. 8, 2006 Radionuclide assessment of coronary artery disease, 1 Mar. 15, 2006 Radionuclide assessment of coronary artery disease, 2 Mar. 29, 2006 Radionuclide assessment of coronary artery disease, 3 Apr. 12, 2006 Radionuclide assessment of coronary artery disease, 1 Apr. 19, 2006 Radionuclide assessment of coronary artery disease, 2 May 10, 2006 Radionuclide assessment of coronary artery disease, 1 Jul. 27, 2006 Radionuclide assessment of coronary artery disease


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Aug. 23, 2006 Radionuclide assessment of coronary artery disease Sept. 26, 2006 Radionuclide assessment of coronary artery disease, 1 Sept. 27, 2006 Radionuclide assessment of coronary artery disease, 2 Oct. 25, 2006 Radionuclide assessment of coronary artery disease, 1 Oct. 27, 2006 Radionuclide assessment of coronary artery disease, 2 Nov. 28, 2006 Radionuclide assessment of coronary artery disease Dec. 19, 2006 Radionuclide assessment of coronary artery disease Jan. 25, 2007 Radionuclide assessment of coronary artery disease Feb. 22, 2007 Radionuclide assessment of coronary artery disease Mar. 27, 2007 Radionuclide assessment of coronary artery disease Oct. 24, 2007 Radionuclide assessment of coronary artery disease Nov. 2007 Radionuclide assessment of coronary artery disease Jan. 23, 2008 Radionuclide assessment of coronary artery disease Feb. 20, 2008 Radionuclide assessment of coronary artery disease Apr. 23, 2008 Radionuclide assessment of coronary artery disease May 21, 2008 Radionuclide assessment of coronary artery disease July 27, 2009 Introduction to Nuclear cardiology, residents & Stress testing Staff, JDVA July 30, 2009 Moderator during guest speaker presentation: Physicians, residents and fellows,

JDVA

Lecture to WSU Radiology Residents: 6/2007 Hybrid Cardiac PET CT imaging (1 hour lecture)

Lectures to WSU PET Center physicians, PhD Students and technical / Nursing Staff: 6/2007 Hybrid Cardiac PET CT imaging (1 hour lecture)


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6/2009 Myocardial perfusion Imaging: the present and the future: implications for fellows training in multi‐modality Imaging

Medical Students: WSU Medical Students MED II: Faculty Cardiac Pathophysiology Course

Feb. 2005 Radionuclide assessment of coronary artery disease (40 min lecture given 8

times), Scott Hall Jan. 2006 “Non‐Invasive assessment of coronary artery disease” (35 min lecture given 8

times), Scott Hall Jan. 2007 “Non‐Invasive assessment of coronary artery disease” (50 min lecture given 4

times), Scott Hall Jan. 2009 Clinic day: “Non‐Invasive assessment of coronary artery disease” (45 min

presentation given 6 times), VA Hospital Feb. 2010 Clinic day: “Non‐Invasive assessment of coronary artery disease and

Introduction to Cardiac non‐invasive Multi‐modality Imaging” (45 min presentation given 6 times), Margherio WSU Conference Center

WSU Faculty: 2004‐present Some WSU faculty members attend my lectures to the Cardiology Fellows. 2005 Symposium Co‐Director and Course Director, Nuclear Cardiology Section. “New

Frontiers in Cardiology,” April 15‐16, 2005, Dearborn, Michigan; CME earning and WSU‐DMC co‐sponsored program. The Nuclear Section included:

Risk Stratification in Chronic CAD (Dr. Bateman) Stress/ Rest Myocardial Perfusion Imaging with Rubidium Cardiac PET (Dr.

Bateman) Role of Nuclear Cardiology and CT in Guiding Patient Management (Dr. Berman) Non Invasive Assessment of Myocardial Viability, Emphasis on Cardiac PET (Dr.

Dorbala) Cardiac MRI: Current Research and Future Indications (Dr. Haacke)

Private Cardiologist 2005 Three day Nuclear Cardiology Preceptor Ship for DMC Cardiologist

Clinical Mentorship: 2004‐present Preceptor of one or two cardiology fellows per year (in addition to being their

nuclear cardiology preceptor) Several career mentoring meetings per year: 2007‐2008 Drs. Ali, Bernal; in 2008‐2009, Dr Faraz 2009, 2010: Dr. Faraz and Hafez


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Misc mentoring to fellows who want to pursue a career in Imaging Write letters in support of fellows

2004‐present New Fellows’ orientation on July 1st of each academic year (2004, 2005, 2006,

2007, 2008, 2009 2004‐present Question writer for Cardiology Fellow’s in house written examinations. Research Mentorship: 1. Is there an incremental value to stress Imaging in Patients with Low Ejection

Fraction and Normal Perfusion on Rest Myocardial Perfusion Imaging? Research preceptor for Dr. M. Kizilbash, cardiology fellow; Abstract published in 2007; Manuscript being written by Dr. Kizilbash under my supervision.

2. Clinical and Scintigraphic correlates in patients with Normal Coronaries.

Research preceptor for Dr. T. Mohammad, cardiology fellow. In progress 3. Research preceptor for Dr. Badheka, internal medicine resident: Effect of

Syncalide on Interpretation of Myocardial Perfusion Sestamibi Images. Abstract presented by Dr. Badheka at WSU research day 2008.

4. Research preceptor to Dr. Mahajan, hospitalist who wants to go into our

cardiology fellowship program: Spectrum of gated SPECT myocardial perfusion imaging abnormalities in patients with left main coronary artery disease: Abstract presented at the American society of nuclear cardiology annual meeting in 2008

5. Case Report on Occurrence of Seizure during Pharmacological Stress Testing.

Research preceptor for Dr. V. Khetarpal, cardiology fellow 6. Significance of a flat diaphragm on myocardial Perfusion Imaging: Relationship

to Pulmonary function tests. Mentor to Dr. Faraz Course or Curriculum Development: (Prior to WSU): 1995‐2003 Founder and Director, Long Island Working Group of the American Society of

Nuclear Cardiology. I organized and directed a nuclear cardiology course through the working group. The following lectures symposia were given:

12/1995 Advances in Pharmacological Stress Testing, Speaker: M. Cerqueira, M.D.

4/1996 Symposium: Nuclear Cardiology for the Clinical Cardiologist and Read with the

Experts; Cold Spring Harbor Laboratory, Long Island. Course Co‐director. Speakers: Drs. Bateman, Berman, Heller, Maddahi.


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5/1996 Advances in Pharmacological Stress Testing. Speaker Mario Verani, M.D.

01/1997 Anti‐Myosin Antibodies Imaging for Cardio‐Vascular Disorders, Speaker Jagat Narula, M.D.

5/1997 Comprehensive Strategy for the Evaluation and Triage of Patients with Recent

Onset of Chest Pain, speaker, James L. Tatum, M.D. 10/1997 Symposium: Rationale and means for Assessing Myocardial Viability, Cold

Spring Harbor Laboratory, Long Island. Course Co‐Director. Speakers: Drs. Rahimtoola, Bateman, Dilsizian, Oz, Bergman, Sandler, Zoghbi

01/1998 Symposium: Pharmacological Stress Imaging in 1998: Changes Concepts and

Read with the Experts; Combined Northeaster Working Groups of the American Society of Nuclear Cardiology. Course Co‐director. Speaker: Drs. Wackers, Sinusas, Udelson, Levine, Miller, McClellan, Leppo, Mahmarian, Cullom, Iskandrian, Bergman, Prigent, Vaccarino

3/1998 Assessment of Myocardial Viability with PET: S Bergman, M.D., and Ph.D. 10/1998 Utility of Cardiac Troponins Serum Levels in Patients with Acute Coronary

Syndromes, Speaker Alan Wu, Ph.D.

5/1999 the Ongoing Evolution of Risk Stratification Using Myocardial Perfusion Imaging, speaker Rory Hachmovitch, M.D.

10/1999 Myocardial Perfusion Imaging for Risk Stratification Following Acute Myocardial

Infarction, Speaker John Mahmarian, M.D.

3/2000 F18‐FDG SPECT Imaging, Speaker E. Gordon De Puey, M.D.

5/2000 Utility of Myocardial Perfusion Imaging in the Emergency Department, Speaker James Udelson, M.D.

2/2001 Risk Stratification in Patients with Acute Coronary Syndromes Using Myocardial

Perfusion Imaging, Speaker Mario Verani, M.D.

10/2001 Risk Stratification with Combined Assessment of Stress Myocardial Perfusion and Function, Speaker Garry Heller, M.D.

4/2002 Symposium: Combined ASNC North‐Eastern Working Group Meeting, Marriott

Marquis, and New York, New York. Course Co director. Speakers: Drs. Mahmarian, Heller, Shaw, Wackers, Bateman, De Puey, Narula, Leppo, Recheck, Prigent. New York City

5/2002 Cardiac PET: A Clinical Reality, Speaker Marcello Did Carla, M.D.


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7/2002 Contemporary Echo/Doppler Assessment of the Heart Failure Patient, Speaker John Gorman II.

4/2003 Nuclear Cardiology Cases PET and SPECT: Steven Bergman, M.D.

5/2003 Technical and Clinical Aspects of Attenuation Correction, Speaker Robert Handel,

M.D. Visiting Professor Lecturer 1992 Los Robles Medical Center, Los Robles, CA, Department of Nuclear Medicine Teaching at other Universities: 1985‐1986 Nuclear Cardiology: Veterans Administration Hospital, Sepulveda, CA 1986‐1988 Nuclear Cardiology course to House Staff: Teaching course of Nuclear Medicine,

Radiology and Internal Medicine Residents and Cardiology Fellows, University of Miami School of Medicine, Miami, FL

1986‐1988 Cardiac MRI: University of Miami School of Medicine, Miami, FL 1986‐1988 Mechanisms of Disease: Course to Medical Students, University of Miami

School of Medicine, Miami, FL 1986‐1988 Faculty Review Course of the University of Miami School of Medicine, Nuclear

Cardiology and Cardiac MRI, Miami, FL . 1986‐1988 Teaching Course, Cardiac Simulation Laboratory, University of Miami School of

Medicine, Miami, FL 1986‐1988 Nuclear Medicine Technologists Teaching Course, University of Miami School of

Medicine, Miami, FL 1988 Application of Magnetic Resonance to Cardiac Imaging: Picker International and

the University of Miami Teaching Course, Miami, FL 1988: Cardiac Imaging, Faculty Review Course of the University of Miami, Miami FL 1988‐1990 Nuclear Cardiology/ Nuclear Medicine: Cedars Sinai Medical Center, Los

Angeles, CA (UCLA) 1990‐1992 Nuclear Cardiology Course to Cardiology Fellows, St. Luke’s/Roosevelt Medical

Center, New York, NY (Columbia University) 1992 Introduction to the Patient: Course to Medical Students, Columbia University

College of Physicians and Surgeons, New York, New York


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1994‐2003 Nuclear Cardiology Course to Cardiology Fellows, Winthrop University Hospital, Minneola, NY (SUNY Stony Brook)

1996 Preceptor in Research: Medical Student Summer Research Program, Winthrop

University Hospital, Minneola (SUNY Stony Brooks) 1997‐2008 Listed as Preceptor in Nuclear Cardiology on the American Society of Nuclear

Cardiology Preceptor Roster. Several outside physicians have applied for 1 –

several weeks’ preceptorship to get credentialed in nuclear cardiology.

However, so far I have not taken any applicants due to lack of infrastructure and

removed our laboratory from the Roster until a structure is in place.

2000: Overview on Nuclear Cardiology, Core Lecture to House‐staff. Winthrop University Hospital, Minneola, NY


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GRANTS CONTRACTS, AND OTHER FUNDING: Active: None Previously Funded Grants and Contracts, WSU Educational grants 2004 Bracco Diagnosis for preceptorship for myself in Cardiac PET 2005 Education grant from: Philips, BMS, Fujisawa, Mallinckrodt for “New Frontiers

in Cardiology” meeting organized by WSU Research grants and contracts 2004‐2007 Medical Director and Research Consultant Title: Exercise and Sleep Study Source: National Institute of Health: PI Dr. Jean Davis, R.N., PhD Total period of support: 4 years. Enrollment closed in 2007; about 50 patients underwent pre and post

treatment exercise stress test studies Site: Wayne State University 2005‐2007 Co‐Investigator Title Serv‐ First for Pulmonary Arterial Hypertension: Study to Evaluate Right

Ventricular Ejection Fraction as Index of Response to Therapy for Pulmonary Arterial Hypertension.

Source: Actelion Pharmaceuticals, US.PI: H. Mubarak, MD, PI initiated Total period of support: 2 Years. Closed in 2007 due to Dr. Mubarak Leaving; Four Patients with Pre and

Post Treatment Studies were Enrolled. Site: Wayne State University/ Harper University Hospital Previously Funded Grants and Contracts, prior to WSU Educational Grants (to fund above described lectures and symposia): 1995 Fujisawa 1996 American Society of Nuclear Cardiology, Hoechst Marion Rousses, Adac,

Capintec, DuPont Pharma, Fujisawa, General Electric, Lee Imaging, Mallinckrodt, Medi‐Physics, Syncor

1997 American Society of Nuclear Cardiology, Centocor, DuPont Pharma, Abiomed,

Adac, Amersham Healthcare, Bayer, Bay Ridge Nuclear Imaging, Bayer, Elscint, Fujisawa, Hoechst Marion Rousses, Key Pharmaceuticals, Mallinckrodt, Merck & Co., Novartis, Pfizer, Picker, Sanofi, Syncor


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1998 American Society of Nuclear Cardiology, Fujisawa, Pet net, Bayer, Amersham, DuPont Pharma

1999 American Society of Nuclear Cardiology, Fujisawa, DuPont Pharma 2000 American Society of Nuclear Cardiology, Pfizer, Park‐Davis 2001 American Society of Nuclear Cardiology, Fujisawa, DuPont Pharma 2002 American Society of Nuclear Cardiology, Syncor, Bracco Diagnostic, Pfizer,

Fujisawa 2003 American Society of Nuclear Cardiology, Bristol Myers Squibb Medical Imaging 2003 Prospective Investigation: The site is being screened by King Pharmaceuticals

for potential participation in study MRE‐0470P involving an Adenosine‐like agent for stress testing.

Research Grants and Contracts: 1982 Co‐Investigator and Research Fellow Title: Ischemic Heart Disease Specialized Center of Research (SCOR) Source: National Heart, Lung and Blood Institute (NHLBI) Total period of support 5 years For: $365,000 Site: Cedars Sinai Medical Center, Los Angeles, CA 1985 Co‐Investigator and Fellow Title: Ischemic Heart Disease, Specialized Center of Research (SCOR) Grant: Unit VII:

“Single Photon Emission computerized Tomography for Quantitative Assessment of Myocardial Perfusion and Ventricular Function.”

Source: National Heart, Lung, and Blood Institute Total period of support 5 years For: $1,099,218 Site Cedars Sinai Medical Center, Los Angeles, CA 1985 Co‐Investigator and Fellow Title: Ischemic Heart disease Specialized Center of Research (SCOR) Grant Unit V:

Nuclear Cardiology Core Source: National Heart, Lung, and Blood Institute Total period of support: 5 years For: $468,475 Site: Cedars Sinai Medical Center, Los Angeles, CA 1986 Co‐Investigator and Fellow Title: Clinical Nuclear Cardiology in Ischemic Heart Disease


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Source: American Heart Association, Greater Los Angeles Affiliate, Investigator Group Fellowship Award

Total period of support: 1 year For: $54,000 Site: Cedars Sinai Medical Center Los Angeles 1989‐1992 Investigator Title Clinical Nuclear Cardiology in Ischemic Heart Disease Source: American Heart Association Greater Los Angeles Affiliate, Investigator Group

Fellowship Award For: $57,000.00 Total period of support: 1 year Site: Cedars Sinai Medical Center Los Angeles 1989 Principal‐Investigator‐Investigator Initiated Title: Reproducibility of Quantitative Stress‐Redistribution T1‐201 SPECT Source: DuPont de Nemours, Inc. Total period of support: 1 year For: $50,000 Site: Cedars Sinai Medical Center, Los Angeles, CA 1989 Co‐Investigator Title: Tc‐99m SESTAMIBI for Assessing Myocardial Perfusion and Function. Source: National Heart, Lung, and Blood Institute Total period of support: 5 Years For: $862, 663 Site: Cedars Sinai Medical Center, Los Angeles, CA 1990‐1991 Co‐Investigator. Investigator Initiated Title: The Ability of Nifedipine GITS to Ablate Ischemia Due to Exercise and Mental

Stress Source: Pfizer Inc For $ 297, 780 Site: St. Luke’s/Roosevelt Medical Center, New York, NY 1997 Principle Investigator‐Investigator Initiated Title: Assessment of Serum Troponin Levels in Patients Presenting to the Emergency

Department with Chest Pain. Source: Bayer: Free Troponin Reagents Total period of support: 2 years Site Winthrop University Hospital, Minneola, NY 1997 Principal Investigator‐ Investigator Initiated Title: Is There a Release of Troponin During Exercise Testing? Source: Boehringer Manheim Total period of support: 2 years For: Free Reagents Site: Winthrop University Hospital, Minneola, New York


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1997 Principal Investigator‐Investigator Initiated Title: Assessment of Glycogen Phosphorylase Is enzyme BB in Patients Undergoing

Exercise Myocardial Perfusion Imaging Source: Pace Diagnostic, Toronto, Canada Total period of support: 2 years For: Free Reagents Sites: Winthrop University Hospital, Minneola, NY and Hartford Hospital, Hartford CT 1997 Principal Investigator‐Investigator Initiated Title: Assessment of Glycogen Phosphorylase Iso‐Enzyme BB in patients presenting to

the Emergency Department with chest pain. From: Pace Diagnostic, Toronto Canada For: Free reagents Sites: Winthrop University Hospital, Minneola, NY and Hartford Hospital Hartford CT 1998 Principal Investigator‐Investigator Initiated Title: Can Serum Levels of Glycogen Phosphorylase ISO‐Enzyme BB be used as a

Marker of Ischemia in Patients Undergoing Myocardial Perfusion Testing? A Pilot Study

Source: Society of Nuclear Medicine Total period of support: 1 year For: $3,000 towards the stipend of a college student Site: Winthrop University Hospital and Hartford Hospital 1999 Principal Investigator‐Investigator Initiated Title: Assessment of Glycogen Phosphorylase Iso‐Enzyme BB in Patients Presenting to

the Emergency Department with Chest Pain For: $9,000.00 Source: Winthrop‐University Hospital Grant Funding Intramural Competition Total period of support: 1 year Site: Winthrop‐University Hospital 1999 Site Co‐Investigator Title: Open Artery Trial From: National Institute of Health Site: Winthrop University Hospital Total period of support: I do not know CLINICAL TRIALS ACTIVITIES WSU 2005 Site Co‐Investigator, Nuclear Cardiology Imaging Title: AMIHOTII (Acute Myocardial Infarction with Hyperoxemic Therapy II). Source: TherOX: PI Dr. J. Richard Spears, PI Initiated Total period of support: 2 years; Study closed due to Dr. Spears Leaving; Four Patients Were Enrolled Site: Wayne State University/Harper Hospital


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WSU, non funded 2004‐2005 Site Principal Investigator Title: A “Multi center Trial to Examine Inducible Myocardial Perfusion Abnormality

Detection with BMS068645 and Adenosine Stress SPECT Compared to Coronary Angiography:

Source: BMS Imaging Total period of support: Closed to enrollment for entire nation Site: Wayne State University/ Harper Hospital 2005‐2006 Site Principal Investigator Title: An Open Label, Multicenter, Phase 3 Study Evaluating the Utility of 123 MIBG

Imaging in Diagnosing Autonomic Dysfunction in Subjects with Symptomatic Heart Failure.

Source: GE Medical Total period of support: Site Closed to enrollment 2006 Site: Wayne State University/ Harper University Hospital 2007‐2008: Co‐Investigator and Principal Investigator for Nuclear Imaging PI: Dr. Robert

Welch Source: Molecular Insight Pharmaceuticals Title: “Open Label, Phase 2 Study of the Safety and Efficacy of I 123 BMIPP for the

Identification of Ischemic Myocardium Using SPECT in Adults with Symptoms Consistent with Acute Coronary Syndrome”

Total period of support: IRB declined for patient with ACS Site: Emergency Department and Nuclear Cardiology 2009: A phase 2, open label, multicenter Study for the development of One Day rest/

Stress cardiac Positron Emission Tomography (PET) Perfusion Imaging Protocols of BMN747158: after site visit, we were not selected because the company had already several investigational sites

Prior to WSU, funded 1987‐1988 Site Principal Investigator Title: Multicenter Trial for the Safety of Diagnostic Accuracy of In‐111‐Labeled

Antimyosin for Detecting Myocardial Necrosis in Ischemic Heart Disease From: Centocor, Inc For: $25,000.00 Site: University of Miami School of Medicine, Miami, FL 1990 Site Co‐Investigator Title: Clinical Evaluation of Tc‐99m SESTAMIBI for Myocardial Perfusion Imaging,

Phase III Source: DuPont de Nemours Inc. Site: St. Luke’s/ Roosevelt Medical Center, New York, NY 1989 Site Co‐Investigator


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Title: Clinical Evaluation of Tc‐99M MIBI as a Substitute for Thallium 201 for myocardial imaging, Phase III

Source: DuPont de Nemours, Inc. Site: Cedars Sinai Medical Center, Los Angeles, CA. 1990 Site Co‐Investigator (Nuclear Cardiology) Title: Late Thrombolysis with TPA Site: St. Luke’s / Roosevelt Medical Center, New York, NY Source: Genentech Inc 1991 Co‐Investigator: Title: A Randomized Multicenter Study to Evaluate the Value of Scintigraphic

Myocardial Perfusion Testing Using Dipyridamole Stress and Sub Maximal Exercise for the Prediction of Future Cardiac Events in Acute Myocardial Infarction Patients.

Source: DuPont Pharmaceuticals. Site: St. Luke’s / Roosevelt Medical Center, New York, NY 1997 Site co‐Investigator Title: An Open evaluation of Carvedilol in patients with chronic congestive heart

failure (NYHA Class II‐IV). From: Smith Kline Beecham Site: Winthrop University Hospital and Winthrop Cardiology Associates, Minneola 1997 Co‐Investigator, Site Principal Investigator Title: Evaluation of Free Fatty Acid‐Binding Protein in Chest Pain Patients Using the

Immuno 1 Analyzer Source: Bayer Corporation For: $20,000 Sites: Winthrop University Hospital, Minneola, NY and New Britain Hospital, CT 1997 Site Co‐Investigator (Nuclear Cardiology) Title: Impress Trial: Inhibition of Metallo Protease by BMS‐186716 in a Randomized

Exercise and Symptoms Study in Subjects with Heart Failure. Source: Bristol‐Myers Squibb Site: Winthrop University Hospital, Minneola, NY 1997 Site Co‐Investigator Title: Metroprolol CR/XL. Study code SH‐MET‐0024‐ A Double Blinded, Placebo

controlled Survival Study with metroprolol CR/XL in Patients with Decreased Ejection and Symptoms of Heart Failure.

Source: Astra, USA, Inc. Site: Winthrop University Hospital 1996 Site Co‐Investigator Title: Sudden Cardiac Death and Heart Failure Trial (SCD‐HeFT) Site: Winthrop University Hospital 1998 Site Co‐Investigator


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Title: TIMI 15 B: a Randomized, Double Blind, Placebo Controlled Study to Assess the safety and Efficacy of IV Klerval administration for 24 to 96 Hours, Followed by Oral Klerval Administration for 4 Weeks, in Patients with Acute Coronary Syndromes.

Source: Rhone‐Poulenc Rorer Research and Development Site: Winthrop University Hospital 1998 Site co‐investigator Title: Amistad II: A Randomized, Double/Blind, Placebo‐Controlled, Multicenter Trial

to Evaluate the Efficiency and Safety of Adenosine (Pallacor, Adenosine Injection) as an Adjunct to Reperfusion Therapy (Thrombolysis or Mechanical Reperfusion) in the Treatment of Acute Anterolateral myocardial Infarction

Source: Medco Research, Inc Site: Winthrop‐University Hospital 1998 Co‐Investigator Title; VEGF Study: A Phase II, Double Blind, Placebo‐Controlled Study to Assess the

Effect of Intra‐coronary and Multiple Intravenous Administrations of rah‐VEGF on Exercise Tolerance in Adults with Viable but Under‐Perfused Myocardium

Source: Genentech Site: Winthrop University Hospital 1999 Site Co‐Investigator Title: Aggressive Study of Restenosis (Adore Study) Site: Winthrop University Hospital 1997 Site Co‐Investigator Title: A Randomized, Open Label, Parallel, Dose‐Finding Study of TNK‐tPA in

Combination with AGGRASTAT in the Treatment of Acute Myocardial Infarction (FASTER Trial)

Source: Merck & Co. Site: Winthrop University Hospital 2000 Co‐Investigator Title: INSPIRE Trial (Adenosine Sestamibi SPECT Post‐Infarction Evaluation) Source: Fujisawa Inc. and DuPont Inc. 2000 Co‐Investigator (Nuclear Cardiology) Title: Clinical Evaluation of the Thoracic Aria Coronary Artery Bypass Graft. Source: Throated Laboratories Site: Winthrop University Hospital 2000 Site Co‐Investigator Title: A Randomized, Open Label, parallel, dose‐finding study of TNK‐tPA in

combination with AGGRASTAT in the treatment of Acute Myocardial Infarction (FASTER Trial)

From: Merck & Co Site: Winthrop University Hospital


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PUBLICATIONS Peer‐Reviewed Publications Original Observation in Referred Journals Cribier A, Berland J, Prigent F*, Letac B: Etude angiographique de la fraction d’’ejection par tiers de systole chez le coronarien. (First third systolic ejection fraction in coronary artery disease: an Angiographic study). Arch maladies du Coeur 75(6):641‐652, 1982 (role: data analysis) Van Train K, Garcia E, Maddahi J, Areeda J, Friedman J, Prigent F*, Waxman A, Berman D: A comprehensive method for the four dimensional quantification and display of thallium‐201 myocardial tomograms. Computers in Cardiology, 1984 (role: clinical validation) Garcia EV, Van Train K, Maddahi JU, Prigent F*, Friedman J, Areeda J, Waxman A, Berman DS: Quantification of rotational thallium‐201 myocardial tomography. J Nucl Med 26:17‐26, 1985 (role: clinical validation) Prigent F*, Maddahi J, Garcia E, Friedman J, Van Train K, Bietendorf J, Swan HJC, Berman DS: Thallium 201 Stress Redistribution myocardial rotational Tomography: Development of criteria for visual interpretation. Am Heart J 109:2:274‐81, 1985 Prigent F*, Maddahi J, Garcia E, Van Train K, Friedman J, Berman D: Noninvasive quantification of the extent of jeopardized myocardium in patients with single vessel disease by stress redistribution thallium 201 Single Photon Emission Computerized Rotational Tomography. Am Heart J. 111 (3): 578‐586 1986 Prigent F, Maddahi J, Garcia E, Satoh Y, Van Train K, Berman D: Quantification of myocardial infarct size by Tl‐201 Single Photon Emission computerized Tomography: Experimental Validation in the Dog. Circulation 74 (4): 852‐861, 1986 Prigent F, Maddahi J, Garcia EV, Resser K, Lew A, Berman DS: Comparative methods for quantifying the extent of myocardial infarction with TI‐2001 SPECT. J Nucl Med. 28:325‐333, 1987 Friedman J, Berman D, Van Train K, Garcia E, Prigent F, Maddahi J: Patient motion in thallium myocardial SPECT imaging: An easily detected frequent source of artifactual defects. J Nucl Med, 13 (5): 321‐324, 1988 (role: analysis, manuscript revision) Friedman J, Van Train K, Maddahi J, Rozanski A, Prigent F, Bietendorf J, Waxman A, Berman DS: Upward creep of the heart, a frequent source of falsely positive reversible defects during TL 201 stress‐redistribution SPECT: J Nucl Med. 30:1718‐1722, 1989 (role: analysis, manuscript revision) Maddahi J, Van Train K, Prigent F, Garcia V, Friedman J, Ostrzega E, Berman D: Quantitative single photon emission computed thallium‐201 Tomography in the evaluation of coronary artery disease: Optimization and prospective validation of a new technique. J Am Coll Cardio 14 (7): 1689‐1699. (Role: key participation in design, analysis. Manuscript writing in part)


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Van Train K, Maddahi J, Berman D, Kiat H, Areeda J, Prigent F, Friedman J: Quantitative analysis of tomographic stress thallium 201 scintigrams: A Multicenter Trial. J Nucl Med. 31 (7): 1168‐1179, 1990. (Role: analysis, manuscript revision) Chouraqui P*, Maddahi J, Ostrega E*, Honma H, Van Train K, Prigent F, Charuzi Y, Berman D: Quantitative exercise Tl‐ 201 rotational Tomography for evaluation of patients following myocardial infarction. Am J Cardio 66 (2):151‐157, 1990 (role: analysis, manuscript revision) Maddahi K, Kiat H, Van Train K, Prigent F, Friedman J, Garcia E, Alazraki N, De Puey Y, Nicholas K, Berman D: Myocardial Perfusion Imaging with Technetium 99mm Sestamibi SPECT in the evaluation of coronary artery disease. Am J Cardio 66:55E‐62E, 1990. (Role: analysis, manuscript revision) Prigent F, Maddahi J, Van Train K, Berman D: Comparison of Rotational Tomography and Planar Imaging for Quantification of Experimental Infarct Size. Am Heart J 122:972‐9, 1991 Prigent F, Berman D, Elashoff J, Rozanski A, Maddahi J, Friedman J, Dwyer J: Reproducibility of Stress‐Redistribution Thallium 201 SPECT Quantitative indexes of Hypoperfused Myocardium Secondary to Coronary Artery Disease: Am J Cardio 70:1255‐1263, 1992 Kiat H, Van Train K, Friedman J, Germano G, Silagan G, Wang F, Maddahi J, Prigent F, Berman D: Quantitative Stress‐Redistribution Thallium 201 SPECT Using Prone Imaging: Methodological Development and Validation. J Nucl Med. 33:1509‐1515, 1992. (Role: analysis, manuscript revision) Klein H*, Rodriguez EA*, Berman D, Prigent F, Chao SY, Maryon T, Rozanski A: Prevalence and functional significance of transient ST segment depression during daily life activity: Comparison of Ambulatory ECG with Stress Redistribution Thallium 201 Single Photon Emission Computed Tomography Imaging: Am Heart J 125:1247‐1257, 1993. (Role: analysis, manuscript revision) Prigent F, Hyun M, Berman D, Rozanski A: Effect of Motion on thallium‐201 SPECT Studies. A simulation and clinical study: J Nucl Med, 34:1845‐1850, 1993 Limacher MC, Douglas PS, Germano G, Larkey WK, Lindsay BD, Mc Kitty MH, Park J, Prigent F, Walsh M: American College of Cardiology Expert Consensus Document “Radiation Safety in the practice of Cardiology” J Am Coll. Cardio: 31 (4):892‐913, 1998 Wu A, Ghani F, Prigent F, Petry C, Armstrong G, Graft L: Reflex testing II: Evaluation of an Algorithm for use of Cardiac markers in the Assessment of Patients presenting to the Emergency Department with Chest pain. Clinical Chim Acta, 288 (1‐2):97‐99, 1999 Ghani F, Wu A, Petry C, Brown A, Armstrong C, Prigent F, Graft L: The Role of Heart Type Fatty Acid‐Binding Protein in Early Detection of Acute Myocardial Infarction. Clinical Chemistry, 46 ((5):718‐719, 2000 CASE REPORTS Lew A, Prigent F*, Maddahi J: Marked precordial ST segment elevation during exercise induced right ventricular Ischemia. Am Heart J 111 (1): 172‐4, 1986


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Pina E, Stang RB, Mallon S, Prigent F, Chahine R: Exercise induced coronary artery spasm after percutaneous angioplasty. Chest 1994:1287‐88, 1988 Prigent F, Hirsh H, Sassower M, Steingart R: Severe reversible left ventricular dysfunction in an elderly man: Utility of thallium 201 myocardial perfusion scintigraphy imaging in the Coronary Care Unit: Cardio‐Vascular Reviews and Reports: 18:53‐56, 1997 REVIEW ARTICLES Klein J*, Berman D, Prigent F, Rozanski A : The Technical and Clinical Applications of Rest and Exercise Radionuclide Ventriculography: Am J Cardiac Imaging 5 (4):291‐304, 1991 Prigent F: Radionuclide assessment of myocardial viability in patients with chronic coronary artery disease: Heart Failure, 11 (3): 110‐123, 1995 Prigent F, Steingart R: Clinical Value of Electron Bean Completed Tomography in the Diagnosis and Prognosis of Coronary Artery Disease. Current Opinion in Cardiology, 12 (6) 561‐565, 1997 BOOKS AUTHORSHIPS, EDITORSHIPS, AND CHAPTERS Marzo K, Prigent F, Steingart RM: Interventional Therapy in Heart Failure Management. Heart Failure in the Elderly. Clin Geriatric Med. 16 (3):549‐566, 2000 ABSTRACTS (LAST FIVE YEARS) Rudriah L *, Kottam a *, Kizilbash M *, Prigent F; is there an incremental value to stress imaging in patients with low ejection fraction and normal perfusion on rest myocardial perfusion imaging? Journal of Nuclear Cardiology, April 2007 Badheka A*, Prigent F: Effect of Syncalide on interpretation pharmacological stress Sestamibi images. WSU SOM Resident competition, 2008 Afonso L, Mahajan N, Prigent F: Spectrum of gated SPECT myocardial perfusion abnormalities in patients with left main coronary artery disease: a tertiary medical center experience. Journal of Nuclear Cardiology, 2008 SOFTWARE PROGRAMS* Inventor of the Localization Scheme Algorithm for the Cedars Sinai Medical Center Thallium ‐201 tomographic quantitative software (Autoquant), while I was a trainee. This scheme is also used for the Cequal software (Sestamibi SPECT Quantitative Software) and for some PET myocardial perfusion imaging software. Completed in about 1996. SCIENTIFIC CORRESPONDENCE

NUCLEAR CARDIOLOGY NEWS UPDATE IN THE JOURNAL OF NUCLEAR CARDIOLOGY:


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Prigent F: How often do you do infarct avid imaging? J Nucl Cardio 4(3): 262‐3, 1997 Prigent F: J Nucl Cardio: 4(4):p346, 1997 Prigent F: What is the most frequent type of nuclear cardiology study done in your geographic region? J Nucl Cardio, 4(5), 432‐8, 1997 Prigent F: Which is better for the diagnosis of viable myocardium, dobutamine echo or thallium? J Nucl Cardio 4(6):591‐592, 1997 Prigent F: How should nuclear cardiologist prepare for the next five to ten years? J Nucl Cardio 5(1):114‐6, 1998 Prigent F: In utilizing a technetium 99m perfusion agent, are most laboratories imaging rest first and stress later, or the reverse? J Nucl Cardio 5(2):240‐1, 1998 Prigent F: Must a physician be present for both a stress test and the imaging? J Nucl Cardio 5(30:356‐364, 1998 Prigent F: Is quantitative approach in routine clinical use in most laboratories? J Nucl Cardio 5(4):453‐6, 1998 Prigent F: Would the development and implementation of an objective standard for accreditation of nuclear cardiology ( or nuclear medicine) laboratories be a useful adjunct to quality assurance in your area? J Nucl Cardio (5(5):546‐8, 1998 Prigent F: Which is the predominant strategy after myocardial infarction in your country? What is the role of stress myocardial perfusion imaging? J Nucl Cardio 5(6):646‐8, 1998 Prigent F: Is there a need for a more standard approach or recommendations for the type of filter and settings used in processing of SPECT studies? J Nucl Cardio 6(1):158‐60. 1999 Prigent F: There is considerable variation in the acquisition of myocardial perfusion studies. We should take a poll to address several issues. J Nucl Cardio 6(2)248‐9, 1999 Prigent F: Are there any guidelines or recommendations for the ratio of technologists and gamma cameras to the volume of studies done per day? J Nucl Cardio 6 (3) 379, 1999 Prigent F: What is your experience with attenuation correction? J Nucl Cardio 6(4) 47508, 1999 Prigent F: How do you handle routine stress testing in‐patients with lung disease? J Nucl Cardio 6(5):552‐4, 1999 Prigent F: In GATED myocardial perfusion studies, which images do you use for perfusion analysis? J Nucl Cardio 6(6), in press, 1999 Prigent F: How do you deal with the assessment of lung uptake in SPECT myocardial perfusion imaging? J Nucl Cardio 7(1):93, 2000


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Prigent F: On routine stress perfusion imaging, how do you grade defect size? J Nucl Cardio 7(2):194‐6, 2000 Prigent F: How many people utilize quantification and bulls‐eyes interpretation for the assessment of perfusion images on all their patients? J Nucl Cardio 7(3):292‐4, 2000 Prigent F: Do you need to combine exercise with Dipyridamole? How do you deal with the reverse redistribution pattern? J Nucl Cardio 7(4):403‐4, 2000 Prigent F: Are you studying more patients this year than you did last year? What do your referring physicians find most helpful in the information provided from a gated perfusion scan? J Nucl Cardio 7(5) 547‐550, 2000 Prigent F: Are the results of Perfusion Imaging reported based on subjective evaluation of the images or does the report include a picture or a statement about quantification? J Nucl Cardio 8(1) 115‐8, 2001 Prigent F: How to develop Nuclear cardiology: Contributions from the International Community. J Nucl Cardio 8(2), 317‐20, 2001 Prigent F: Has the use of fast CT and calcium scores had an impact on the number of perfusion scans? J Nucl Cardio 4: 535‐8, 2001 Prigent F: Which is the current practice in your country with regards to the role of non‐invasive tests in general and the roles of stress myocardial perfusion imaging after acute coronary syndromes? J Nucl Cardio 5: 633‐6, 2001 Prigent F: When is the withdrawal of the medical therapy indicated and when is it not, before myocardial perfusion imaging? J Nucl Cardio 5:633‐6, 2001 Prigent F: How commonly is cardiac FDG imaging performed in your country to assess myocardial viability and what proportion is dedicated PET Vs coincidence Vs collimated SPECT? J Nucl Cardio, in press 2002 Prigent F: What percentage of perfusion studies is done for pre‐operative clearance? J Nucl Cardio 9:2252‐4, 2002 Prigent F: Are you satisfied with the left ventricular ejection fraction results of gated single photon emission computerized Tomography results received in different clinical subsets. J Nucl Cardio 9:3, 355‐8, 2002 Prigent F: Can your software allow simultaneous display of both stress and rest gated images? J Nucl Cardio 4:448‐50, 2002 Prigent F: Which adenosine dose do you use for patients with weigh>250 lbs ? J Nucl Cardio July/August 2002 Prigent F: What is the first line test for myocardial viability at your institution? J Nucl Cardio November/December issue 2002


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Prigent F: Does your nuclear cardiology workstation software allow movies of gated single photon emission computed Tomography? J Nucl Cardio January/February 2003 Prigent F: Do you use more than one tracer for perfusion imaging in your laboratory? J Nucl Cardio, 2003 Prigent F: Do you remotely read any Nuclear Cardiology Studies, e.g.: emergency room studies for acute chest pain after hours: J Nuclear Cardio 10(3):339‐341, 2003 Prigent F: Is the use of electron beam computed Tomography for coronary calcium and computed Tomography affecting the pattern of referral for myocardial perfusion imaging in your laboratories? J Nucl Cardio, July/August 2003 Prigent F: What percent patients are referred for Myocardial Perfusion imaging for a work up of heart failure? J Nucl Cardio, September/October, 2003 Prigent F: Do you use the Internet to read nuclear studies? Nucl Cardio November/December, 2003 Prigent F: In your country are doctors performing nuclear cardiology required to have some training in health physics, radiobiology and radiochemistry? J Nucl Cardio, January/February, 2004 This section of the Journal of Nuclear Cardiology was terminated by Editor 2/2004 Theses/Dissertation* 1981: Dissertation for the Gold Medal Competition of Rouen University Hospitals: Vasodilators in Cardiac Surgery. (Intérêt des Vasodilatateurs en Chirurgie Cardiaque: Mémoire pour le Concours de la Médaille d'Or), Rouen, France 1981: Thesis for medical degree: “Contribution a l’ etude d’un vasodilateur, la Nicergoline, en cours d’anesthesie generale pour chirurgie Cardiaque” (Assessment of the effect of Nicergoline, a new Vasodilator during general anesthesia for Cardiac Surgery), University of Rouen, France


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INVITED LECTURES / PRESENTATIONS Invited/refereed presentation at international/national meetings 1982: Hemodynamic effect of new vasodilator, Nicergoline during sternotomy for Open Heart Surgery. Canadian Anesthesiology Society National Meeting, Quebec, Canada 1982: A new objective approach for assessing left ventricular function at rest and during exercise using phase analysis of Radionuclide Ventriculography. American Heart Association 55th Scientific Sessions, Dallas, TX 1982: Comparison of rotational Tomography with planar imaging for thallium ‐201 stress myocardial scintigraphy. Society of Nuclear Medicine National Meeting, St Louis, MO 1984: Quantification of myocardial hypo perfusion in single vessel disease using stress redistribution TL‐ 201 single photon emission computerized Tomography (SPECT). American College of Cardiology National Meeting, Dallas, TX 1984: Quantification of the extent and severity of myocardial Ischemia in single vessel disease using stress redistribution thallium 201‐ Single Photon Emission Computerized Tomography, Society of Nuclear Medicine National Meeting, Los Angeles, CA 1984: Quantification of Myocardial Infarct Size in the dog using Single Photon Emission Computerized Tomography: slice by slice comparison of thallium 201 tomograms and pathology. American Heart Association National Meeting, Miami, FL 1985: Single Photon Emission Computerized Tomography for quantification of experimental Myocardial Infarct Size. American College of Cardiology National Meeting, Anaheim, CA 1985: Comparative Methods for Quantifying Total Left Ventricular Infarct size in vivo by Single Photon Emission Computerized Tomography (SPECT). Society of Nuclear Medicine National Meeting, Houston, TX 1985: Quantification of percent Hypoperfused myocardium required correction for individual myocardial slice mass. American Heart Association 58th Scientific Sessions, Washington, DC 1986: Is Tl‐201 SECT better suited than planar imaging for the quantification of myocardial infarct size? Society of Nuclear Medicine National Meeting, Washington, DC 1986: Quantification of stress redistribution TL‐201 single Photon Emission Computerized Tomography: Development of a scheme for localization of coronary artery disease. Society of Nuclear Medicine National Meeting, Washington, DC 1988: Magnetic Resonance Imaging in Myocardial Sarcoidosis. Society of Nuclear Medicine National Meeting, San Francisco, CA 1989: Quantification of % Hypoperfused myocardium by Tl‐201 SPECT: Development of an algorithm for correction for variation in myocardial slice Mass. Society of Nuclear Medicine National Meeting


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1989: Reproducibility of quantitative indices of Hypoperfused myocardium on follow‐up stress redistribution Tl‐201 studies. Young Investigators Award Competition, Society of Nuclear Medicine National Meeting, St. Louis, MO 1989: Effects of Motion of Thallium‐201 SPECT Images. American Heart Association National Meeting, New Orleans, LA 1990: Quantification of experimental myocardial infarction size with Tc‐99 MIBI: Experimental validation in the dog. American College of Cardiology Annual Meeting, New Orleans, LA 1990: Meta‐diagnosis of the experienced reader interpretation of SPECT Ti‐201 studies. National Meeting of the Society of Nuclear Medicine, Washington, DC 1990: Effect of Motion on Thallium‐201 studies: A clinical and simulation study. Workshop, Annual Meeting of the Society of Nuclear Medicine, Washington, DC 1990: Quantification of total left ventricular infarct size in the dog using Tc‐99m Sestamibi SPECT. Workshop 7th International Congress Cardiostim, Nice, France 1990: Quantification of total Left Ventricular Myocardial Infarct size with diastolic Tc‐99m MIBI SPECT: Experimental Validation in the dog. National Meeting of the Society of Nuclear Medicine, Washington DC 1990: Effect of Gating and Matrix size for myocardial perfusion defect sizing with Tc‐99m Sestamibi SPECT. American Heart Association Annual Meeting, Dallas, TX 1990: Effect of Gating and Matrix size for myocardial perfusion defect sizing with Tc‐99mm Sestamibi SPECT: 7th Convention on Information Cardiologique, Paris France 1995: Reader’s Confidence in Interpretation: Relationship to the Diagnostic Accuracy of Thallium SPECT Imaging. American Heart Association Annual Meeting, Anaheim, CA 1997: Are the Scintigraphic patterns different in Ischemic and Non‐Ischemic Cardiomyopathies? Third International Conference of Nuclear Cardiology, Florence, Italy 1998: Different Scintigraphic Patterns in Ischemic vs. Non‐Ischemic Cardiomyopathy. American College of Cardiology National Meeting, Atlanta, GA 1998: A novel enzymatic Assay of Glycogen Phosphorylase ISO‐enzyme GG as a Marker of Ischemia in Patients Presenting to the Emergency Room with Chest Pain. World Congress of Cardiology, Rio de Janeiro, Brazil 1998: Are the Scintigraphic patterns different in Ischemic vs. Non‐Ischemic Cardiomyopathy? World Congress of Cardiology, Rio de Janeiro, Brazil 1998: Can Glycogen Phosphorylase ISO‐Enzyme BB be used as a Marker if Ischemia in Patients Undergoing Exercise Testing? American Society of Nuclear Medicine Annual Meeting, Toronto, Canada


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1998: Can Glycogen Phosphorylase ISO‐enzyme BB be used as a Marker of Ischemia in Patients Presenting to the Emergency Room with Chest Pain? American Heart Association Meeting, Dallas, TX 1999: Meet the Expert: How to Interpret the Difficult Perfusion Scan. Sixth International Conference of Nuclear Cardiology, Athens, Greece 2000: Long Term Reproducibility of a Normal myocardial Perfusion Scan. Annual Meeting of the Society of Nuclear Medicine, St. Louis, MO 2001: Hot Spots Artifacts on Myocardial Perfusion SPECT Images: A Retrospective Study of Potential Causes and Impact on Specificity. May 2001, Fifth International Congress of Nuclear Cardiology, Vienna, Austria 2001: SPECT Myocardial Perfusion Imaging Correlates in Patients with and without Inducible Ventricular Tachycardia during Electro physiologic testing. Fifth International Congress of Nuclear Cardiology Vienna, Austria

2001: Poster display of national and regional working group of the American Society of Nuclear

Cardiology: Long Island Working Group. ICNC 5, Vienna, Austria

INVITED/REFEREED PRESENTATIONS AT LOCAL/REGIONAL MEETINGS 1984: Quantification of Myocardial Infarct Size using Single‐Photon Emission Computerized Tomography. Experiment validation in the dog. Western Regional Meeting, Society of Nuclear Medicine, Monterey, CA 1984: Quantification of myocardial infarct size using single‐photon computerized tomography. Experimental validation in the dog. Young Investigators’ Forum, American Heart Association, Greater Los Angeles Affiliate, Torrance, CA 1985: Comparison of Single Photon Emission Computerized Tomography and Planar Imaging for Quantification of Experimental Myocardial Infarct Size. Society of Nuclear Medicine, Western Regional Meeting, Palm Springs, CA 1985: Comparative methods for Quantifying total LV Infarct size in Vivo by Single photon Emission Computerized tomography. Young Investigators’ Forum, American Heart Association, Greater Los Angeles Affiliate 1985: Stress‐redistribution T1‐201 Single Photon Emission Computerized Tomography: Development of a scheme for computerized localization of coronary artery disease, Society of Nuclear Medicine Western Regional Meeting, Palm Springs, CA. 1987: New Concepts in Thallium‐201 Scintigraphy. South Florida Technologist Chapter, Parkway Hospital, Miami, FL 1987: New Developments in Cardiac Magnetic Resonance Imaging. American Heart Association, Greater Miami Chapter


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1988: Application of Magnetic Resonance to Cardiac Imaging. Picker International and the University of Miami Teaching Course, Miami, FL 1988: New Cardiac Imaging Modalities. Florida Chapter of the American College of Cardiology, Orlando 1989: Quantification of % hypoperfused myocardium by TL‐201 SPECT: Development of an algorithm of correction for variation of myocardial slice mass in man. Young Investigator Competition, American Heart Association, Greater Los Angeles Affiliate, Los Angeles, CA 1989: Study of the Effect of Motion on Thallium‐201 SPECT images. Western Regional Meeting of the Society of Nuclear Medicine, Monterey, CA 1989: Optimal acquisition and processing parameters for Tc‐99m Sestamibi myocardial imaging. Western Regional Meeting of the Society of Nuclear Medicine, Monterey, CA 1989: Assessment of the prevalence of ambulatory ST segment depression in patients referred for thallium‐201 stress testing. Western regional meeting of the Society of Nuclear Medicine 1989: Correlation of ischemic indices during stress thallium‐201 scintigraphy and ambulatory electrocardiography. Western Regional Meeting of the Society of Nuclear Medicine. 1990: Quantification of total left ventricular infarct size with gated Tc‐99m Sestamibi SPECT. Young investigator competition of the American Heart Association Greater Los Angeles Affiliate, Los Angeles CA 1990: Meta‐analysis of experienced reader’ interpretation of Thallium‐201 SPECT studies. New York Chapter of the Society of Nuclear Medicine, New York, NY 1990: Case Review with the Experts Presentation: Presenter. Joint Symposium of the Northeastern American Society of Nuclear Cardiology Working Groups, New York, NY 1996: Comparison between low‐level and symptom limited Thallium‐201 SPECT imaging in patients following myocardial infarction. Long Island American Heart Association Chapter: Annual Meeting, North Shore University Hospital, Manhasset, NY 1997: Difference in Scintigraphic pattern in Ischemic vs. Non‐Ischemic Cardiomyopathies. Stony Brook Department of Medicine Annual Meeting, Nassau County Medical Center, Hempstead, NY 1997: Is the extent of ischemia similar on low level and symptom limited thallium‐201 SPECT imaging in patients following myocardial infarction. Stony Brook Department of Medicine Annual Meeting, Nassau County Medical Center, Hempstead, NY. 1997: Comparison between low‐level and symptom limited myocardial perfusion studies in patients following myocardial infarction. Long Island American Association Chapter: Annual Meeting, North Shore University Hospital, Manhasset, NY 1998: Case Review with the Experts Presentation: Symposium on pharmacological Imaging. Joint Symposium of the Northeastern American Society of Nuclear Cardiology Working Groups New York, NY


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1998: A Novel enzymatic Assay of Glycogen Phosphorylase ISO‐Enzyme BB as a Marker of Ischemia in Patients Presenting to the Emergency Room with Chest Pain. SUNY Stony Brook Department of Medicine Annual Meeting, Stony Brook, NY 1998: Can Glycogen phosphorylase ISO‐Enzyme BB be used as a Marker in Patients Undergoing Exercise Testing? SUNY Stony Brook Department of Medicine Annual Meeting, Stony Brook, NY 1999: Diagnostic Utility of glycogen Phosphorylase ISO‐Enzyme BB in Elderly Patients with Acute Coronary Syndrome. Comparison with Troponin. Society of Geriatric Cardiology, New Orleans, LA 2000: Radionuclide Assessment of Myocardial Viability: Long Island Society of Nuclear Technologists, Huntington Hospital, NY; (audience: technologists and physicians) 2000: Advances in Pharmacological Stress Testing: Long Island Society of Nuclear Medicine Technologists, Huntington Hospital, Huntington, NY; (audience: technologists and physicians) 2002: Meet with the expert presentation”. “Advancements in Nuclear Cardiology”. Combined Northeast ASNC Working Groups Meeting, New York, NY 2005: Case Presentation. “Stress testing in presence of WPW syndrome”. Michigan Chapter of the American Society of Nuclear Cardiology, Fellow’s Competition, Ann Arbor, MI 2005: Judge, Michigan Chapter of the American Society of Nuclear Cardiology Fellow’s competition, Ann Arbor, Michigan INVITED SEMINARS AND GRAND ROUNDS 1980: Use of new Vasodilator, Nicergoline in Cardiac Surgery. Working Group for Anesthesia for Cardiac Surgery. Hospital de la Pitie‐Salpetriere, Paris France 1984: Cardiology Grand Rounds : Quantitative stress redistribution thallium myocardial Perfusion Imaging; Hospital Charles Nicole, Rouen France 1985: Clinical Applications of Nuclear Cardiology: Lecture to the Cardiology House‐staff. Veterans Administration Hospital, UCLA School of Medicine, Sepulveda, CA 1986: Introduction to Nuclear Cardiology. Invited lecture to Medicine House‐staff. Veterans Administration Hospital, UCLA School of Medicine, Sepulveda, CA 1987: Radiology Grand Rounds: New Developments in Nuclear Cardiology; Cedars Medical Center, Miami FL 1988: Radiology Grand Rounds: Nuclear Medicine and Magnetic Resonance in Cardiac Imaging, Broward General Hospital, Miami Shores, FL 1990: Nuclear Cardiology: Cases review with the experts: Myocardial Perfusion Imaging Reading Sessions; American College of Cardiology Extra‐Mural Programs. Cedars Sinai Medical Center, Los Angeles, CA


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1990: Nuclear Cardiology: Case review with the experts: Radionuclide Ventriculography Reading Sessions; American College of Cardiology Extra‐Mural Programs. Cedars Sinai Medical Center, Los Angeles, CA 1990: “Late Thrombolysis” Ancillary Protocol: Volume study with Radionuclide Ventriculography. Toronto, Canada 1990: Nuclear Cardiology studies for the assessment of the extent and severity of coronary artery disease and myocardial viability; Nuclear Cardiac Imaging with new Tracers: Columbia University College of Physicians and Surgeons. New York, NY 1990: Medicine Grand Rounds; Advances in Nuclear Cardiology. St. Luke’s /Roosevelt Medical Center, New York, New York move to grand rounds 1992: Cardiology Grand Rounds: Nuclear Cardiology: Basic Principles and Clinical Applications; Centre Cardio‐Thoracique de Monaco, Monaco 1995: Department of Medicine Grand Rounds: New Developments in Nuclear Cardiology; Winthrop University Hospital, Minneola, NY 1996: Combined Medicine/Radiology Grand Rounds: Advances in Pharmacological Stress Testing; White Plains Medical Center, White Plains, NY 2001: Radio Pharmaceuticals and Protocols. Practical Applications of Nuclear Cardiology: a fellow’s tutorial. Metropolitan Hotel, New York, NY; Organized by the American Society of Nuclear Society 2007: WSU Department of Medicine Grand Rounds: Hybrid Cardiac Imaging 2009: WSU Department of Medicine Grand Rounds: Multimodality Imaging


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APPENDIX CONTINOUS MEDICAL EDUCATION 2004‐PRESENT 2004‐present Continuous Education Program, Cardiology, Harper University Hospital 2004 Symposium on Attenuation Correction, Cardiovascular Imaging Technology, Kansas

City, MO 2004 Preceptorship in Cardiac PET: Cardiovascular Imaging Technology, Kansas City, MO 2004,05,06 American Society of Nuclear Cardiology Annual National Meeting 2005 Preceptorship in Cardiac PET and Cardiac CT: Cardiovascular Imaging Technology,

Kansas City, MO 2005 Cardiovascular MRI and CTA Angiography for the Cardiologist: American College of

Cardiology Foundation. Washington, DC 2005 Investigator meeting “Prognosis usefulness of I‐123 mIBG Scintigraphy for

identifying subjects with Heart Failure who will experience an adverse cardiac event 2005, 06, 07, and 08 Cardiovascular CT for the Cardiologist: Credentialing Course of the American

Society of Nuclear Cardiology for CT Angiography. Milwaukee, WI 2005 3 Day Course‐CT Angiography Vitrea Training Course, Minneapolis, MN 2005 Coronary Computed Tomography and Hybrid Systems, Cleveland Clinic, Cleveland,

OH 2006, 07, 08, 09 Society Nuclear Medicine Annual Meeting 2006 Cardiac CT Course, University of Michigan, Ann Arbor, MI 2007 CT Training at Beaumont hospital, Royal Oak, MI, 1 week 2008 CITTI examination

2008 Society of Cardiac Computed Tomography: Second Annual Meeting and Board Review course

2009 Society of Cardiac Computed Tomography: Third Annual Meeting and Board Review

course 2009 Level 3 Training: MD imaging network. Course for level III Preparation

2009 American Heart Association, Annual Scientific Sessions


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CONTINOUS MEDICAL EDUCATION (Before 2004): CARDIOLOGY: 1988‐1990 Continuous Education Program, Cedars Sinai Medical Center, Los Angeles, CA 1982‐2000 American Heart Association, Annual Scientific Sessions 1983‐1985 American Heart Associations, Greater LA Affiliate, CA: Fall Meeting 1984‐1992 American College of Cardiology, Annual Scientific Sessions 1994, 1997‐2000 American College of Cardiology, Annual Scientific Sessions 1990‐1992 Continuous Education Program, St. Luke’s / Roosevelt Medical Center 1994‐2003 Continuous Education Program, Winthrop University Hospital, Minneola, NY NUCLEAR MEDICINE / NUCLEAR CARDIOLOGY MRI CT: 1983, 1992, 1994 Society of Nuclear Medicine Annual Meeting 1996, 1998, 2000 Society of Nuclear Medicine Annual Meeting 1983‐1985, 1989 Western Regional Meetings of the Society of Nuclear Medicine 1985‐1987 Symposium on MRI (Educational Symposia), Orlando, FL 1990 Investigator Meeting on Antimyosin Antibodies 1990‐93 Manhattan Nuclear Medicine Annual Meetings 1993 South‐Eastern Chapter, Society of Nuclear Medicine 1993‐1995 International Congress of Nuclear Cardiology 1997, 99, 2001 American Society of Nuclear Cardiology Annual National Meeting 1993‐2000 American Society of Nuclear Cardiology Annual National Meeting 1994 Diagnostic & Therapeutic Applications of Radio labeled Antibodies and Receptors for

Diagnostic and Therapeutic Purposes. University of Miami, FL 1996 Training in PET Imaging. Department of Nuclear Medicine UCLA School of Medicine,

Los Angeles, CA OTHER COURSES: 1990‐2005 Domestic Violence and HIV/AIDS to Satisfy Requirements for Licensing in Florida


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1998 Introduction to Computers, Winthrop University Hospital, NY 1998, 2000, 2002 Infection Control, Winthrop University, NY 1998, 2000, 2001 Conscious Sedation, Winthrop University, NY 2001 WUH Training Course for Investigational Review Board Members 2001 NIH Course: “Human participant Protections Education for Research” FORMER EDUCATION: 1963‐1970 Junior High and High School: Lycee de Lillebonne, 76, France (Categories:

Mathematics and Physics) OTHER EDUCATION: 1974 Medical School, summer 1974, Albany University Medical Center, Albany NY OTHER EXAMINATIONS: 1967 “BEPC” (Examination at the end of Junior High School)

Documents

florence prigent, md, bs, facc, fasnc