AboutTheJob.

Department of Human MetabolismFaculty of Medicine, Dentistry and Health

Senior Lecturer in Musculoskeletal Biology

Pursue the extraordinary

The Faculty of Medicine, Dentistry and Health is one of the major UK centres for education and research in health and related subjects. With origins dating back to 1828, the faculty has a longstandingtradition of excellence in clinical education and research.

Over 2,500 students study in the faculty each year on over 40 different courses. In addition, over 200 students are registered on research degrees, supporting a faculty research portfolio in excess of £30M.

Independent assessments of our teaching and research quality rate us as among the best in theUK.

For more information on the Faculty of Medicine, Dentistry & Health, please seehttp://www.shef.ac.uk/faculty/medicine-dentistry-health/

The Department of Human Metabolism combines strong basic and clinical science groups to create a major focus on translational research. This is well illustrated by the integration of the Biomedical Research Unit for Bone within the department. The research strengths are in the fields of Musculoskeletal Research, Endocrinology, Diabetes and Reproductive Medicine with cross-cutting themes in Clinical Pharmacology.

Research activity is supported by state of the art molecular biology laboratories, dedicated clinical research facilities and access to the latest imaging technology including MR, NMR and PET scanning. The department has strong links with the Sheffield Institute for Maternal, Fetal and Neonatal Imaging (SIMFANI). The main areas of musculoskeletal research are in osteoporosis, childhood bone disease, inflammatory arthritis, bone oncology, bone responses to endocrine and environmental stimuli, and the Mellanby Centre for Bone Research is located within the department. Reproductive research is in fertility, andrology and the department hosts one of the most successful Assisted Conception Units in the country, with facilities for human embryonic stem cell derivation. The Diabetes Group has a focus on hypoglycaemia, neuropathy and diabetic education. The Endocrinology Group has expertise in pituitary and autoimmune thyroid disease with research programmes

About the Department

Overview

directed at optimising endocrine replacement therapy. The Clinical Pharmacology Group has extensive expertise in pharmacokinetic-pharmacodynamic modelling, human drug metabolism and pharmacogenetics.

Research activity is supported through a broad portfolio of research funding. This includes project and programme grant support from major UK funding organizations such as the Medical Research Council, NIHR, the Arthritis Research Council, Diabetes UK and Leukaemia and Lymphoma Research. Substantial support from biotechnology and pharmaceutical companies has formed the basis for a significant knowledge transfer activity and the department supports four University spinout companies (Asterion, Diurnal, Medella, Health Care Solutions). A major emphasis of the department is in career development. This has been demonstrated by the success of members of the theme in attaining personal support through Fellowship schemes, which include NIHR, Arthritis Research Council Clinician Scientist and Clinical Research Fellowship awards.

For more information on the Department of Human Metabolism, please seehttp://www.shef.ac.uk/medicine/humanmetabolism

Library FacilitiesThe University Clinical Library is housed on ‘C’ Floor of the Royal Hallamshire Hospital. TheMedical Library is in the main University Library which is within half a mile of the RoyalHallamshire Hospital and offers excellent lending reference and national lending (Boston Spa)facilities.As part of the Faculty of Medicine Dentistry and Health’s Medical School redevelopment, theHealth Sciences Library (HSL) at RHH was reconfigured and refurbished during 2012. Moreinformation can be found at www.shef.ac.uk/library/libnews/rhhrefurb

This post has arisen as a result of investment in areas of research strength in musculoskeletal biology and oncology. Reporting to the Head of Department of Human Metabolism, you will play a key role in the development of collaborative links between the Mellanby Centre for Bone Research, the new Cancer Research UK /YCR Centre and the multidisciplinary Insigneo Institute. It is anticipated that you will use those links as leverage for further large awards. Research interests in the area of

Job Role

cancer cells interactions with bone cells and small animal imaging may be an advantage, but expertise in other areas of musculoskeletal biology would be appropriate.

The University's expectations of the qualities and responsibilities of its academic staff are captured by the concept of the Sheffield Academic. The role of the Sheffield Academic is underpinned by a number of core values and qualities that are essential to the scholarly pursuit and communication of knowledge in this University. Among them is the recognition that the pursuit of research excellence and the pursuit of teaching excellence are closely linked. Please see www.sheffield.ac.uk/hr/sheffieldacademic/statement.html for further information.

Main Duties and Responsibilities

Contribute fully as a researcher, teacher and leader, in fulfilment of the ideals of the

‘Sheffield Academic’ (http://www.shef.ac.uk/jobs/uni/sheffieldacademic).Lead and conduct innovative research and scholarship of a substantial internationalreputation in the field of bone research. Maintain high output of publications in highimpactjournals, influential monographs, highly-regarded books, conferenceproceedings or other academic recognised works within the field.Foster collaborations with researchers in the Mellanby Centre for Bone Research(MCBR), Cancer Research UK/YCR centre, Insigneo Institute and the wider Faculty,University and clinical environment in Sheffield.Contribute to the development of the MCBR centre of excellence in bone.Generate income through winning research grants in excess of the UK median for thediscipline. This will include obtaining funding from research councils. Manage/co-manageexternal research funding and contracts over period of grant(s).Recruit candidates to external research fellowships, increase postgraduate researchstudent numbers.Participate in the implementation of innovative teaching methods. Proactively support

Job Description

the implementation of teaching policy. Act as a role model for colleagues, helping theirdevelopment with regard to teaching quality.Carry out course evaluation including facilitating student feedback; reflecting on ownteaching design and delivery and implementing ideas for improving performance.Contribute to formulation of teaching policy.Carry out a pastoral role for students and clinical trainees such as acting as a PersonalTutor, or as Course Director or Mentor to counsel students. If necessary refer them tothe appropriate authority for guidance.Supervise and develop undergraduate and postgraduate research students, clinicaltraining fellows and research staff.Provide academic leadership and mentorship both within the department and morebroadly in the discipline.Act in roles at faculty/school/departmental committees in order to contribute to thedevelopment of teaching/learning policy locally.Grow the external recognition of the Department and the University through academicachievement and involvement in external professional activities such as refereeing papers,editorial board positions with scientific journals, refereeing research grants, externalexamining, or participating in the organisation of international conferences.Undertake teaching-related and administrative work allocated by the Head ofDepartment.Lead a research project and/or group, planning its work and delegating work to theappropriate staff.Manage Research Assistants and/or Research Associates and/or Clinical Training Fellows.Deal with reactive requests daily such as those relating to teaching, supervising researchstaff and students and administrative tasks.Any other duties, commensurate with the seniority of the post.

Applicants should provide evidence in their applications that they meet the following

Person Specification

criteria. We will use a range of selection methods to measure candidates’ abilities in these areas including reviewing your on-line application, seeking references, inviting shortlisted candidates to interview and other forms of assessment action relevant to the post.

Criteria Essenti Desirable

Qualifications and experience1. Bachelor’s degree in a relevant subject and a higher research

degree e.g. PhD (or equivalent experience).X

2. Previous experience in an academic position. X3. Significant personal record of research in the relevant subject

area, with a proven track record of producing high quality publications.

X

4. Evidence of scholarship that is recognised internationally in terms of originality, significance and rigour.

X

5. Current grants including a proven ability to attract research grants as a Principal Investigator.

X

Supporting staff performance6. Evidence of scholarship that is recognised internationally in

terms of originality, significance and rigour.X

7. Experience in small group teaching and lecturing to larger groups at undergraduate and post-graduate students.

X

8. Experience of successful supervision of doctoral students. X9. Experience of academic leadership and the ability to

contribute to departmental management.X

Management skills10. Experience of managing research projects. X11. Experience of formal/informal supervision of students,

technical staff and research staff.X

12. Ability to manage interdisciplinary working. X13. Ability to lead a research team. X

Communication skills14. Excellent communication skills, both written and verbal,

including effective use of technology where appropriate.X

15. Responsible for maintaining effective collaborations and liaising with collaborators both nationally and abroad.

X

Team working16. Experience of leading and motivating a team undertaking X

collaborative and multidisciplinary research.17. Experience of developing a team and aligning the day-to-day

work and goal of the team with the organisation’s strategic vision.

X

18. Ability to motivate high performance in others. X19. Experience of reviewing individual/team progress and

performance and embedding organisational strategy into individual performance planning.

X

Project management20. Excellent organisational skills and the ability to manage

multiple projects.X

21. Ability to take responsibility for own progress and plan appropriate contingences.

X

22. Ability to assess and organise resources, and plan and progress work activities.

X

Personal effectiveness23. Experience of developing and maintaining a network of

contacts throughout own work area.X

24. Ability to work accurately in order to meet tight deadlines. X25. Excellent interpersonal skills. X26. Well-established personal reputation and professional

standing.X

27. Experience of adapting own skills to new circumstances. X28. Ability to think and act strategically. X

This post is full-time: This role has been identified as a full-time post, but we are committed to exploring flexible working opportunities with our staff which benefit both the individual and the University. Therefore, we would consider flexible delivery of the role subject to meeting the business needs of the post. See www.sheffield.ac.uk/hr/wellbeing/info/wlb.html for more information.

Further Information

Benefits

Terms and conditions of employment: Will be those for Grade 9 staff. Salary for this grade: £47,314 - £53,233 per annum. Potential to progress to £61,689through sustained exceptional contribution.

More details on salaries, terms and conditions and our wide range of benefits for staff are available at www.sheffield.ac.uk/hr/reward/structures

*Please note that any current and previous salary details included in your application may beviewed by members of the selection panel.*

Closing date: 16 October 2013

Informal enquiries:For all on-line application system queries and support, contact: e-Recruitment@sheffield.ac.uk .

For informal enquiries about this job and department, contact: Professor Tim Skerry, Head of Department on hodhm@sheffield.ac.uk or 0114 271 2414.

Following the closing date, you will be informed by email whether or not you have been shortlisted to be invited to participate in the next stage of the selection process. Please note that due to the large number of applications that we receive, it may take up to two working weeks following the closing date before the recruiting department will be able to contact you.

It is anticipated that interviews and other selection action will be held on XXX. Full details will be provided to invited candidates.

The University of Sheffield is committed to achieving excellence through inclusion.

The University of Sheffield is proud to be a Two Ticks employerwww.sheffield.ac.uk/hr/equality/support/twoticks/

Selection-Next Step

The University has achieved the Athena SWAN award for Women in Science, Engineering and Medicine.

The Medical School has achieved the Athena SWAN silver award for Women in Science, Engineering and Medicine.

The Faculty of Medicine, Dentistry & Healthhttp://www.shef.ac.uk/faculty/medicine-dentistry-health/

Pursue the extraordinary

The Faculty of Medicine, Dentistry and Health is one of the major UK centres for education and research in health and related subjects. With origins dating back to 1828, the faculty has a longstanding tradition of excellence in clinical education and research.

Over 2,500 students study in the faculty each year on over 40 different courses. In addition, over200 students are registered on research degrees, supporting a faculty research portfolio in excessof £30M.

Independent assessments of our teaching and research quality rate us as among the best in the UK.

With over 250 academic and clinical staff, and 250 research associates, the faculty has the trainingand development of staff at the centre of its strategic priorities. A tailored training programme -Think Ahead - in line with the Concordat to Support the Career Development of Researchers isavailable to all researchers in the faculty. This includes an induction process; workshops linked toworking-based learning opportunities; employer lead career days; and tailored support in preparation for the end of a contract. A newly developed career mentoring scheme with academic, industrial and alternative careers' strands gives practical support for career development in your chosen destination. The portfolio of transferable skills and career development courses is continuously updated and tailored to the researcher and the employer needs and to fit with the strategic aims of the faculty. For more information on current opportunities see http://www.sheffield.ac.uk/faculty/medicine-dentistry-health/thinkahead or email Lucy Lee (L.Lee@sheffield.ac.uk).

The Medical Schoolhttp://www.sheffield.ac.uk/medicine/Sheffield School of Medicine was founded in 1828, subsequently merging with Firth College (1879),forerunner of the University, and Sheffield Technical School (1884) to form University College Sheffield in 1897. The University of Sheffield was granted a Royal Charter in May 1905.

The Medical School today is home to more than one thousand students at undergraduate andpostgraduate levels. Our aim is to provide high quality, innovative teaching and research to ensuretomorrow's doctors are best equipped to tackle disease.

The school's activities incorporate teaching, research and the practice of medicine. Our coursesexpose medical students to best current practice, through learning with the excellent Primary andSecondary care providers in the region.Equally important is the research we engage in to contribute to developing the medicine oftomorrow. In the 2008 Research Assessment Exercise, we submitted to 6 Units of Assessment.Overall, 90% of our research was assessed as internationally recognised with 60% of research inUoAs 2 and 4 being rated world-leading or internationally excellent. We increased substantially thenumber of staff submitted and our research power ranks us 11th out of the 20 Russell GroupMedical Schools.

Department of Infection and Immunityhttp://www.shef.ac.uk/medicine/infectionandimmunity

The department combines basic science research in molecular cell biology, with a particular focuson innate immunity, with clinical specialties including Respiratory Medicine, Infectious Diseases,Renal Medicine, Rheumatology and Dermatology.

There is a very substantial base of Wellcome Trust, MRC and BHF grant funding. The departmentincludes two MRC and one Wellcome Trust Senior Clinical Fellows and one Wellcome IntermediateClinical Fellow. There are also a number of Clinical and Non-Clinical Research Fellows funded byMRC, Wellcome Trust, ARC and Kidney Research UK.

There is extensive expertise in vertebrate and mammalian models of chronic inflammatory andinfectious diseases. There is also a strong track record of high quality clinical and translationalresearch. There are strategic links to the MRC Centre for Developmental and Biomedical Geneticsand to the Department of Molecular Biology and Biotechnology within the University of Sheffield.

Department of Human Metabolismhttp://www.shef.ac.uk/medicine/humanmetabolism

The Department of Human Metabolism combines strong basic and clinical science groups to create a major focus on translational research. This is well illustrated by the integration of the Biomedical Research Unit for Bone within the department. The research strengths are in the fields of Musculoskeletal Research, Endocrinology, Diabetes and Reproductive Medicine with cross-cutting themes in Clinical Pharmacology.

Research activity is supported by state of the art molecular biology laboratories, dedicated clinicalresearch facilities and access to the latest imaging technology including MR, NMR and PET scanning. The department has strong links with Sheffield Institute for Maternal, Fetal and Neonatal Imaging (SIMFANI). The main areas of musculoskeletal research are in osteoporosis, childhood bone disease, inflammatory arthritis and bone oncology and the Mellanby Centre for Bone Research is located within the department. Reproductive research is in fertility, andrology and the department hosts one of the most successful Assisted Conception Units in the country, with facilities for human embryonic stem cell derivation. The Diabetes Group has a focus on hypoglycaemia, neuropathy and diabetic education. The Endocrinology Group has expertise in pituitary and autoimmune thyroid disease with research programmes directed at optimising endocrine replacement therapy. The Clinical Pharmacology Unit has extensive expertise in pharmacokinetic-pharmacodynamic modelling, human drug metabolism and pharmacogenetics.

Research activity is supported through a broad portfolio of research funding. This includes projectand programme grant support from major UK funding organizations such as the Medical Research

Council, NIHR, the Arthritis Research Council, Diabetes UK and the Leukaemia Research Fund.Substantial support from biotechnology and pharmaceutical companies has formed the basis for a

significant knowledge transfer activity and the department supports four university spinoutcompanies (Asterion, Diurnal, Medella, Health Care Solutions). A major emphasis of thedepartment is in career development. This has been demonstrated by the success of members ofthe theme in attaining personal support through Fellowship schemes, which include NIHR, ArthritisResearch Council Clinician Scientist and Clinical Research Fellowship awards.

Department of Oncologyhttp://www.shef.ac.uk/medicine/oncology

The Department of Oncology at The University of Sheffield has an extensive research programmefrom basic science through to clinical trials. The department is part of the Sheffield Cancer RearchCentre supported by CRUK and YCR. There are three main groupings in the department. The Institute for Cancer Studies (Head, Professor Mark Meuth) receives core funding from Yorkshire Cancer Research and the major focus of research relates to genomic instability and DNA repairmechanisms. The clinical trials unit at Weston Park Hospital (Head, Professor Robert Coleman)has major areas of research in the field of bone oncology, particularly the role of bisphosphonatesin the prevention and management of patients with bone metastases. The third major area ofresearch is tumour microcirculation and micro environment (Professor Gill Tozer and ProfessorNicola Brown) and the tumour targeting group, (Professor Claire Lewis). There are many otheropportunities for both clinical and scientific research in a range of disciplines ( breast, GI, Urological cancers and sarcoma) Cancer research in the Department of Oncology receives

extensive funding from Cancer Research UK, Yorkshire Cancer Research, NIHR, LeukaemiaResearch Fund and other national and local research organisations.

In addition to these areas, the department includes the Academic Units of Urology, SupportiveCare, Human Nutrition and Ophthalmology. All of these have strong areas of research activity bothwithin their specific fields and integrating with the areas outlined above.

Together with Medical Education and the other four departments that comprise the MedicalSchool, the Department of Oncology makes a substantial contribution to teaching in theundergraduate medical curriculum. The department also hosts the Undergraduate degree coursein Optometry and a Postgraduate Master’s course in Human Nutrition contributing to the Master’scourse in Molecular Medicine.

Department of Neurosciencehttp://www.shef.ac.uk/medicine/neuroscience

The Neuroscience Department comprises multidisciplinary groups from Neurology,Neuropathology, and Academic Clinical Psychiatry (that also includes a strong interest inneuroimaging) working in both basic and clinical neuroscience. The major areas of researchinterest are in neurodegenerative diseases (diseases of the motor system, basal ganglia anddementia); psychiatric disorders (psychosis and major affective disorders) and neuroimaging. TheNeurodegenerative Disease group research portfolio includes genetic, cellular, molecular andclinical research into common disorders including motor neuron diseases, Parkinson’s disease,Huntington’s disease and the ageing brain and dementia. The research focus is stronglytranslational and a new 2,800m2 research facility, the Sheffield Institute of Translational

Neuroscience (SITraN) was officially opened by Her Majesty The Queen, in November 2010. TheAcademic Clinical Psychiatry group within which the Sheffield Cognition and NeuroimagingLaboratory (SCANLab) resides, has major research programmes investigating perception inauditory and visual modalities and their interaction; time perception and processing; social cognition and executive function in health and psychiatric disease. Structural and functional MRIare the main neuroimaging techniques used to define these processes.

There are strong collaborative links with other Neuroscience groups within the University ofSheffield, including: the neuroradiology group which focuses on the investigation of the causes andsequelae of cerebrovascular disease; neurodegenerative processes and foetal and childhooddevelopmental brain abnormalities; the MRC Centre for Development and Biomedical Genetics(CDBG) which has major strengths in developmental neuroscience and in model systems forneurodegenerative disease; the Cognitive Neuroscience and Neuroimaging groups in theDepartment of Psychology and with tissue engineering and nanotechnology groups within theKroto Institute.

Research activity within the Neuroscience Department is supported through a broad portfolio ofresearch funding. This includes project and programme grant support from major UK fundingorganizations such as the Wellcome Trust; Medical Research Council; NIHR; EU and multipleneurological and psychiatric disease related charities. Substantial funding from biotechnology andpharmaceutical companies supports our translational and clinical research programmes. TheNeuroscience Department attaches great importance to career development. We have an

excellent track record of attracting prestigious external fellowship awards and six of these fellowshave recently progressed to faculty positions within the department.

Department of Cardiovascular Sciencehttp://www.sheffield.ac.uk/cardiovascularscience/index

The Department of Cardiovascular Science has sustainable, internationally excellent research andteaching in the core areas of Cardiovascular Biomechanics (including Virtual PhysiologicalHuman concepts translated to man), Vascular Inflammation and Thrombosis andHaemostasis. There is particular expertise in pulmonary hypertension (PH), vascular biology,magnetic resonance (MR) imaging, experimental models of disease, systems biology, datasimulation and management and translational clinical science, particularly in coronary arterydisease and PH.

Research activity is supported by state-of the art laboratories for experimental models (includingbiological services and aquaria), cell and molecular studies. There is a dedicated NIHR clinicalresearch facility (CRF) (www.sheffield.crf.nihr.ac.uk) as well as the Sheffield Institute for Maternal,Fetal and Neonatal Imaging (SIMFANI). We have considerable expertise with preclinical imaging andimaging in man including the use of hyperpolarised gases.

The department is funded by programme and project grants from the EU, MRC, Wellcome, BHF,BBSRC and NIHR. There are several clinical and non-clinical research training fellows and lecturersfunded by MRC, NIHR and BHF. The department teaches a highly successful CardiovascularPathway within the MSc in Molecular Medicine.

The department has strong links with The University of Sheffield Centre for Developmental and

Biomedical Genetics (CDBG), Insigneo (Institute for in silico medicine) and with Sheffield TeachingHospitals NHS Foundation Trust, particularly through close integration with the academicdirectorates of cardiology and cardiothoracic surgery and respiratory medicine (PH).

Academic Unit of Medical Educationhttp://www.shef.ac.uk/aume/index.html

The goal of the Academic Unit of Medical Education is to provide high level professionaleducational services to support and enhance the teaching role of the medical school. In doing so, itwill undertake research and development activities which will establish a national and internationalreputation as a centre of excellence in the field of medical education.

The academic unit provides high level professional educational services to support and enhancethe teaching role of the medical school. Academic staff in the unit undertake research anddevelopment activities, which seek to establish a national and international reputation as a centreof excellence in the field of medical education.

The unit has responsibility for:Curriculum development, management and enhancementStaff developmentResearch in medical educationOperating the clinical skills centreOverseeing the Patients as Educators programmeThe use of information technology for curriculum management and communicationbetween staff and students, via Minerva, our managed learning environmentCollaborative and consultancy activities, locally, nationally and internationally

Academic staff in the unit have a range of research interests including, competency based assessment, professionalism, curriculum evaluation and interprofessional education.The curriculum of the MBChB course integrates clinical medicine and medical sciences throughout

all years. Both academic staff and NHS clinicians teach and assess students. There are opportunities for students to undertake intercalated Bachelor of Medical Sciences courses andshort research attachments lasting a few weeks as part of the MBChB curriculum.