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WHAT IS INFLAMMATION
o The word "inflammation" traces back to the Latin for "set afire."
o Inflammation refers to your body's process of fighting against
things that harm it to heal itself (such as infections, injuries and
toxins). When something damages your cells, the body releases
chemicals that trigger a response from the immune system.
o Inflammation is good in the short run. It's part of your immune
system's natural response to heal an injury or fight an infection.
It's supposed to stop after that. But if it becomes a long-lasting
habit in your body, it can be bad for you. Long-term, or "chronic,"
inflammation is seen in many diseases and conditions.
TYPES OF INFLAMMATION
o Inflammation can be either short-lived (acute) or long-lasting (chronic):
o • 5 cardinal signs characterize acute inflammation: Calor or Heat (Due to increased
blood flow), Rubor or Redness (Due to dilation of blood vessels), Tumor or Swelling,
formally called “localized oedema” (Due to increased permeability of vessels and
resultant extravasation of protein-rich fluid), Dolor or Pain (Due to chemical
mediators such as bradykinin), and Functio laesa or Loss of function. Acute
inflammation is generally considered a process which lasts several days. Following
this time, several outcomes may result.
o • Chronic inflammation is also called persistent because it produces a steady, low-
level of inflammation throughout the body. A perceived internal threat can trigger low
levels of inflammation, even when there isn't a disease to fight or an injury to heal,
and sometimes this signals the immune system to respond. As a result, white blood
cells swarm but have nothing to do and nowhere to go, and they may eventually start
attacking internal organs or other healthy tissues and cells. Researchers are still
working to understand the implications of chronic inflammation on the body and the
mechanisms involved in the process. Yet, it's known to play a role in the development
of many diseases. Conditions linked to chronic inflammation include Cancer, Heart
disease, Diabetes, Asthma, Alzheimer's disease, depression, etc.
OUTCOME
Acute Chronic
CauseHarmful pathogens or
tissue injury.
Pathogens that the body cannot
break down, including some types
of viruses, foreign bodies that
remain in the system, or
overactive immune responses.
Onset Rapid. Slow.
Duration A few days. From months to years.
Outcomes
Inflammation improves, or
an abscess develops or
becomes chronic.
Tissue death, thickening, and
scarring of connective tissue.
The following table summarizes some key differences between acute and
chronic inflammation. It is essential to identify and manage inflammation
and related diseases to prevent further complications.
RISK FACTORS
Factors that may increase the risk of inflammation include:
o Older age
o Compromised immune system
o Obesity
o A diet that is rich in unhealthful fats and added sugar
o Smoking
o Low sex hormones
o High levels of stress
o Sleep problems
o Deficiencies
o Sedentary lifestyle
o Pollution (including EMF and Smog)
YOUR DIET MATTERS
If you want to reduce inflammation, eat fewer inflammatory foods and more anti-inflammatory foods.
o Base your diet on whole, nutrient-dense foods that contain antioxidants — and avoid processed products.
o Antioxidants work by reducing levels of free radicals. These reactive molecules are created as a natural part of your metabolism but can lead to inflammation when they're not held in check. Your anti-inflammatory diet should provide a healthy balance of protein, carbs, and fat at each meal. Make sure you also meet your body's needs for vitamins, minerals, fiber, and water.
o Three diets are considered anti-inflammatory: the Mediterranean diet, which has been shown to reduce inflammatory markers, such as CRP and IL-6. A low-carb diet also reduces inflammation, particularly for people who are obese or have metabolic syndrome. Lastly, vegetarian diets are linked to reduced inflammation
o The types of food you eat affect how much inflammation you have. Get plenty of fruits, vegetables, whole grains, plant-based proteins (like beans and nuts), food rich in omega-3 fatty acids (such as fish, algae, seeds and nuts), and healthier oils, like olive oil. Also, eat foods with pre and probiotics. Limit saturated fats, found in meats, whole-fat dairy products, and processed foods.
FOODS TO AVOID
Some foods are associated with an increased risk of chronic inflammation. Consider minimizing or cutting these out completely:
o Sugary beverages: Sugar-sweetened drinks and fruit juices
o Refined carbs: White bread, white pasta, etc.
o Desserts: Cookies, candy, cake, and ice cream
o Processed meat: Hot dogs, sausages, etc.
o Processed snack foods: Crackers, chips, and pretzels
o Additives, dyes, preservatives, and other ingredients regularly added to foods all have the potential to trigger or aggravate inflammation, particularly if you have a weaker gut barrier
o Certain oils: Processed seed and vegetable oils like soybean and corn oil
o Trans fats: Foods with partially hydrogenated ingredients
o Alcohol: Excessive alcohol consumption
FOODS TO EAT
Include plenty of these anti-inflammatory foods:
o Vegetables: Broccoli, kale, Brussels sprouts, cabbage, cauliflower, etc.
o Fruit: Especially deeply coloured berries like grapes and cherries
o High-fat fruits: Avocados and olives
o Healthy fats: Olive oil and coconut oil
o Fatty fish: Salmon, sardines, herring, mackerel, and anchovies
o Nuts: Almonds and other nuts
o Peppers: Bell peppers and chilli peppers
o Chocolate: Dark chocolate
o Spices: Turmeric, fenugreek, cinnamon, etc.
o Green tea
o Red wine: Up to 5 ounces (140 ml) of red wine per day for women and 10 ounces (280 ml) per day for men
THE 7 FIGHTERS
o Omega-3 fatty acids influence inflammation through a variety of mechanisms;
o Vitamin B can reduce acute and chronic inflammation and modulate immune reaction.
o Zinc is a potent anti-inflammatory that may support the immune system and reduce several markers of inflammation.
o Gold shows anti-inflammatory, antibacterial, antivirus effects.
o Vitamin C is an antioxidant that helps get rid of free radicals that can damage cells and tissue, which means fewer triggers for inflammation. Regularly intake of Vitamin C can lower the chance of chronic inflammation and heart disease.
o Curcumin, which is an active ingredient in turmeric, is shown to be helpful in reducing inflammation and speeds up wound healing.
o Boswellia serrata resin, or frankincense, can ease both inflammation and pain.
NANO GOLD
o Gold is taken into intracellular organelles and stored in lysosomes. There, it both inhibits the
processing of antigenic agents and blocks the reactive processes that produce and release
inflammatory cytokines.
o Research that was initially directed at the use of gold in rheumatoid arthritis evolved to show
potential applications in antimicrobial therapy as well as antiviral therapy. The same
mechanisms of action are being explored for possible anticancer and antimicrobial effects. Gold
nanoparticles in a cancer cell appear to accelerate cell death as well as upregulate tumour-
suppressing signals.
o Gold has also been shown to both inhibit cell growth of certain infectious microbes and make
these cells more susceptible to oxidative stress and death. Laboratory researchers have
demonstrated that relatively low intracellular concentrations of gold microparticles exhibit
decisive inhibitory action against cultures of methicillin-resistant Staphylococcus aureus. Many
studies show the anti-inflammatory, analgesic and anti-tumour effects of Gold nanoparticles.
o Gold assists in the programming of RNA and DNA and protect the nucleic acids from free
radical damage.
o Take 10-30ml of Nano Gold in the evening for calming. Hold it for a minute in the mouth to
allow the mineral to be absorbed directly into the bloodstream through the sublingual duct
under the tongue and surrounding tissue.
NANO ZINC
o Zinc plays an intricate function during an immune response; its homeostasis is critical for sustaining proper immune function. It is proven that mild deficiency in Zinc decreases T-cell proliferative responses by 20%.
o Zinc deficiency results in increased susceptibility to infectious disease, due to reduced thymus size, depleted macrophages and lymphocytes in the spleen, and decrease T-cell function and antibody responses.
o The immune system is especially affected by the modification of zinc homeostasis. Achieving an optimal immune response to different stimuli and avoiding damage of tissues and organs requires a delicate balance that relies, amongst other factors, on the regulation of Zinc in extracellular and intracellular compartments.
o Zinc is involved in many biochemical activities as a cofactor of many enzymes, such as superoxide dismutase, an antioxidant enzyme.
o According to a 2014 paper, Zinc decreased inflammation and oxidative stress among older adults. Oxidative stress triggers inflammation and may increase the risk of a host of conditions. Zinc also reduced the rate of infections by 66%.
o Take 10-60 ml Nano Zinc as desired during the day or before going to sleep. Keep in the mouth for about 1 minute before swallowing to promote direct absorption from the oral mucosa into the bloodstream.
RESISTANCE RX
o Curcumin is a component of the spice turmeric. It provides several impressive health benefits.
Curcumin also appears to be very beneficial for reducing inflammation and improving symptoms
of osteoarthritis and rheumatoid arthritis. One randomized controlled trial found that people with
metabolic syndrome who took curcumin had significantly reduced levels of the inflammation
markers compared to those who received a placebo. In another study, when 80 people with solid
cancerous tumours were given 150 mg of curcumin, most of their inflammatory markers
decreased much more than those in the control group. Their quality of life score also increased
significantly. Also, a 2011 study found that curcumin may help reduce inflammation from obesity-
related metabolic conditions. Curcumin altered several inflammatory pathways, reducing insulin
resistance, hyperglycemia, and hyperlipidemia.
o Curcumin is poorly absorbed, so it needs to be boosted – Micellar delivery is the answer!
o Olibanum, or frankincense, can ease both inflammation and pain. It also helps reduce cartilage
loss and reverse autoimmune symptoms. It is a fast-acting supplement that may help with
osteoarthritis pain in just 5 days. Combining frankincense with curcumin may increase its
potency, and some research has found that people tolerate this combination better than the non-
steroids anti-inflammatory medications.
o Vitamin C is known for helping keep the immune system healthy and functioning well. Moreover,
research shows vitamin C can get rid of free radicals responsible for inflammation. Vitamin C also
helps lower C-reactive proteins, a compound responsible for inflammation.
PHYTALITY ULTANA PHYTOPLANKTON
o Omega 3 is associated with changes in the fatty acid composition of cell
membranes. Changes in these compositions can modify membrane fluidity, cell
signaling leading to altered gene expression, and the pattern of lipid mediator
production. EPA and DHA give rise to newly discovered Resolvins which are anti-
inflammatory and inflammation resolving. Resolvins are a group of molecules
derived from omega-3 fatty acids. They are part of a biochemical program that
allows inflamed tissues to return to homeostasis once the need for the
inflammatory response is over.
o Vitamin B can lower your levels of homocysteine, an amino acid linked to a higher
risk for heart disease, rheumatoid arthritis, other chronic inflammation and
modulate immune reaction. Also, oeople with low vitamin B6 will often have high
C-reactive proteins, another compound responsible for inflammation, especially in
autoimmune diseases such as rheumatoid arthritis. To reduce inflammation and
increase vitamin B6, try consuming foods high in B vitamins, including kale, bell
peppers, and mushroom, cantaloupe, tuna, and poultry. A study found even low
doses of folic acid (also known as folate, another B vitamin) supplementation
taken daily and for short periods can reduce inflammation.
o Take 1 flat teaspoon or 3 capsules (1 gram) a day in the morning.
FOR LUNG INFLAMMATION ADD NANO PLATINUM
o Imbalance oxidative status occurs when the production of ROS and the oxidative
stress is higher in the body due to exposure or inflammation.
o Reoccurrence of oxidative stress in the lung cells will eventually lead to inflammation
and oedema, which will result in a severe prognosis of lung diseases. A 2015 study
shows that Platinum nanoparticles (PtNPs) are one of the powerful antioxidants that
can quench free radicals. The mechanistic pathway may involve Protein Kinase C,
which correlates well with the expression of the Epithelial Sodium Channel (ENaC).
These channels play an important role in sodium uptake, thus stimulate lung liquid
clearance. The failure of lung clearance will interrupt gaseous exchange, thus
eventually lead to death. The antioxidant effect of the PtNPs optimizes these
function, freeing the lungs from excessive fluid production.
o A 2008 study investigated the therapeutic effects of Platinum Nanoparticles on
pulmonary inflammation by cigarettes smoke (CS). CS exposure caused depletion of
antioxidant capacity, NF activation, and neutrophilic inflammation in the lungs.
Intranasal administration of PtNPs was found to inhibit these changes, and it did not
elicit pulmonary inflammation or toxicity. In in vitro experiments, PtNPs inhibited cell
death after exposure to a CS extract. These results suggest that platinum
nanoparticles may act as antioxidant inhibiting pulmonary inflammation induced by
cigarette smoking and other pollutants.
LIFESTYLE
o Stay Active.
o Get Some Sleep.
o Reduce Allergens.
o Stop Smoking
o Reduce stress
o Alkalise your body
o Drink lots of water
o Integrate herbs and spices to your diet
o Consider intermittent fasting (IF)
o Reduce EMF Exposure
HERBS & SUPPLEMENTS
o Vitamin E is an antioxidant that also has anti-inflammatory action
o Vitamin A plays a role in keeping your immune system from overreacting and causing
inflammation. Some studies on beta-carotene point to a slower progression of rheumatoid
arthritis.
o Vitamin K lowers levels of inflammatory signs. But we don't know yet if that also reduces
your risk for related diseases.
o Vitamin D shows a significant anti-inflammatory effect on cells. There's also some
evidence that D can lessen the ongoing pain from inflammation. Low vitamin D levels
have been linked to inflammatory diseases, including rheumatoid arthritis, lupus,
inflammatory bowel disease, and multiple sclerosis.
o CBD (otherwise known as the non-psychoactive component of hemp) has real substance
and efficacy, especially when it comes to chronic inflammation. CBD is gaining traction as
a fantastic anti-inflammatory supplement for many conditions raging from chronic
inflammation to anxiety, stress reactions, and more.
o Bromelain is a group of enzymes found in pineapple juice and the pineapple stem. People
use it as a medicine. It is used for pain, muscle soreness, and many other conditions and
to reduce swelling.
o Garlic contains diallyl disulfide, an anti-inflammatory compound that limits the effects of
pro-inflammatory cytokines. Therefore, garlic can help fight inflammation and may even
help prevent cartilage damage from arthritis.
THANK YOU!
Susanna Saiu
Noble Naturals Nation Trainer Manager
Email: [email protected]
This information is provided for training
purposes only and it is not a substitute for
professional advice. All content is the
property of Noble Naturals Ltd. protected
by copyright laws, do not copy, reproduce,
distribute, publish or display this
information without the prior written
permission from Noble Naturals Ltd.