Fat Soluble Vitamins: Functions and Its Deficiency

7/29/2019 Fat Soluble Vitamins: Functions and Its Deficiency

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PRINCIPLE OF HUMAN NUTRITION

FAT SOLUBLE VITAMINS: FUNCTIONSAND ITS DEFICIENCY


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What do

Vitamins

contain?

Fat-solubleVitamins

(A,D,E,K)

Water-soluble

Vitamins(C, B

complex)

Vitamins should contain


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What is the difference

between fat-soluble

Vitamins and water-soluble

vitamins?

Fat-soluble vitamins

are stored in theliver and fatty

tissues.

Water-soluble vitaminstravel into the blood and

stored in water-filled

parts of body. Eg;kidney


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Fat-solubleVitamins


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VITAMIN


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What is

Vitamin A?

Previtamin A:

- Retinol

- Retinal

- Retinoic Acid Provitamin A:

- Carotenoids

(beta-carotene)


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Functions

Vision

- Generates pigments for the retina- Maintains surface lining of eye s

Bone growth

Reproduction

Cell division and differentiation

Healthy Skin

Regulate Immune System


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Where does

it come

from?


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Signs of

Deficiency

*Night blindness

*Decreased resistance to infections

*Extremely dry skin, hair or nails


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Too MuchCan Be

Toxic!!

*Hypovitaminosis A leads to toxic

symptoms:- GI system: Liver abnormalities

- Bone & Tooth: < bone mineral

density

- CNS: Headache

- Other: Retinoid embryopathy


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VITAMIN


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What is

Vitamin D?

Provitamin D:

- Cholecalciferol (vitamin D3)

Active Vitamin D:

- 1,25-dihydroxytamin D3

also called

- 1,25-dihydroxycholecalciferol

(calcitriol)


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Functions

Hormone-like

- mineralization of bones

- Cell metabolism


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Where does

it come

from?


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Toxicity can

result in:

*GI System: nausea and

vomiting

*Cardiovascular: High bloodCalcium

* Other: Kidney stones


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VITAMIN


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What is

Vitamin E?

- Family of compounds called

tocopherols and tocotrienolsthat are naturally in foods. It

has strong antioxidants.

- An antioxidant are molecules

which can safely interact with

free radicals and terminate the

chain reaction before vital

molecules are damaged.

mj


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Vegetable oils (such as wheatgerm, sunflower, safflower, corn,and soybean oils)Nuts (such as almonds, peanuts,and hazelnuts/filberts)Seeds (such as sunflower seeds)Green leafy vegetables (such asspinach and broccoli)Fortified breakfast cereals, fruitjuices, margarine, and spreads


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Cardiovascular system:- Hemolytic anemia in infants

Central Nervous System:

- Neuropathy in the geneticdisorder

Neuromuscular system:

- Skeletal weakening in the

genetic disorder


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Too MuchCan Be

Toxic!!

*Only described when taken in veryhigh levels as supplement

High intake of vitamin E can potentially

interfere with vitamin K role in

blood clotting and act as a pro-

oxidant, increase red blood cell

hemolysis


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VITAMIN


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What is

Vitamin K?

- Vitamin K refers to two

naturally occurring fat-soluble

vitamins, vitamin K1 and

vitamin K2.

- Vitamin K1 is also known asphylloquinone while vitamin

K2 known as naphthaquinones


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Blood Clotting

Bone Metabolism


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o No disease name, rareexcept with newborns and

following certain medical

measures.

o Cardiovascular system:Increase clotting time,

heamorrhaging with a cut

or injury


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Too MuchCan Be

Toxic!!

*Poor described in adults

Cardiovascular system:

- Interferes with anti-blood

clotting medications.

GI system:

- Jaundice and liver damage in

infants


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SUMMARYToxicities and deficiencies take

longer to develop for FSV rather

than WSV.

The FSV are group by their

solubility in oil.

The FSV have specific chemical

forms and function in the body.

Deficiencies and toxicity signs andsymptoms are unique for each

nutrient as are food source.


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THANK

YOU

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Fat Soluble Vitamins: Functions and Its Deficiency