RISK FACTOR OF STROKENur Latifa Mursiana Helma Kumala, S. KedSTASE NEUROLOGIRSUD dr. DORIS SYLANUS ! "K UN#AR#ALANGKA RAYA$%&'Risk Factors of StrokeKhan H, Arfdi AK, Ashraf S. Pak J Med Sci. !!". #o$.%o. &The ro$e of h'(ertension ) the risk of stroke*ersh +J, Freed,an JE, *ran-er C+. Re. Es( Cardio$. !//0"12134"!5"6Chronic Endothelial Injury hypothesis in atherosclerosis formsK7,ar, A88as, Fa7sto, Mitche$$. Ro88ins +asic Patho$o-'. 6th ed. !!9.H'(othetica$ se:7ence of ce$$7$ar interactions in atherosc$erosisAtherosclerosis and its major complication, myocardial infarction, are strongly linked to cigarette smoking.ATHEROSCLEROSIS ATHEROSCLEROSIS In(reased )latelet a**re*ati+nDe(reased t,res,+ld f+r -entri(ular ./rillati+nDe(reased m0+(ardial +10*en su))l02O )r+du(ed /0 (i*arette sm+3e In(reased O$ demand Hypoxia+Signifcant lung diseaseK7,ar, A88as, Fa7sto, Mitche$$. Ro88ins +asic Patho$o-'. 6th ed. !!9.Ho; atria$ f8ri$$ation can ca7ses stroke =onne$$ CP. Ph'sio$ Re. ?!4 19@//, !/!.A%TIHAPERTE%SI#E =RB*S I% SPECIAC CO%=ITIO%SNur Latifa Mursiana Helma Kumala, S. KedSTASE NEUROLOGIRSUD dr. DORIS SYLANUS ! "K UN#AR#ALANGKA RAYA$%&'+$ood (ress7re ,od7$ationK7,ar, A88as, Fa7sto, Mitche$$. Ro88ins +asic Patho$o-'. 6th ed. !!9.+$ood (ress7re and the RAAS*enera$ (atho-enesis of H'(ertensionK7,ar, A88as, Fa7sto, Mitche$$. Ro88ins +asic Patho$o-'. 6th ed. !!9.Possi8$e co,8inations of c$asses of antih'(ertensi.e dr7-sDIURETIKA2E4I 5 AR6Ca$ci7, Channe$ +$ocker 2CC+3Men*,am/at in7u3s 2a$8 )ada sel +t+t )+l+s )em/ulu, dara, 5 mi+3ard.Rela3sasi terutama arteri+l, sedan* -ena 3uran* di)en*aru,i.G+l. Di,idr+)iridin 9DH#, 0a3ni nifedi)in, ni3ardi)in, isradi)in, fel+di)in, 5 aml+di)in: /ersifat -as3ul+sele3tif men*untun*3an 3;