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EUROACTIONA model for secondary and primary preventive care to
achieve ‘25 by 25’
Professor David A WoodGarfield Weston
Professor of Cardiovascular MedicineInternational Centre for Circulatory Health
Imperial College London United Kingdom
Cardiopulmonary rehabilitation
“Cardiac rehabilitation is a branch of rehabilitation medicine dealing with
optimizing physical function in patients with cardiac disease”
Wickipedia September 2nd 2013
Cardiac rehab §°
95% CI Secondary prevention ¶
95% CI
Total mortality 0.80 0.68, 0.93 0.85 0.77, 0.94
CHD mortality 0.74 0.61, 0.90 - -
Myocardial re-infarction 0.79 0.57, 1.09 0.83 0.74, 0.94
§ Taylor R et al, Am J Med 2004; 116:682-692 ¶ Clark A M et al Annals of Internal Medicine 2005;143:659-672. °Heran B S, et al Cochrane Database of Systematic Reviews 2011
Randomised controlled trials of cardiac rehabilitation and secondary
prevention
Secondary preventionAll cause mortality
Secondary preventionAll cause mortality
Treatment Control Relative Risk
95% CI
Programmewith no exercise
4598 4604 0.87 0.76, 0.99
Programmewith exercise
2404 2251 0.88 0.74, 1.04
Exercise only 1165 1120 0.72 0.54, 0.95
Overall* 8167 7975 0.85 0.77, 0.94
*p=0.001
Clark A M et al Annals of Internal Medicine 2005;143:659-672
Secondary PreventionRecurrent myocardial infarction
Secondary PreventionRecurrent myocardial infarction
Treatment Control Relative Risk
95% CI
Programmewith no exercise
2787 2742 0.86 0.72, 1.03
Programmewith exercise
2075 1922 0.62 0.44, 0.87
Exercise only 1124 1073 0.76 0.57, 1.01
Overall* 5986 5737 0.83 0.74, 0.94*p=0.002
Clark A M et al Annals of Internal Medicine 2005;143:659-672
Cardiac rehabilitation is a branch of rehabilitation medicine dealing with
optimizing physical function in patients with cardiac disease.
While the ‘glue’ of cardiac rehabilitation is exercise, programmes are evolving to
become comprehensive prevention centerswhere all aspects of
care are delivered.
Wickipedia September 2nd 2013
Comprehensive prevention centers where all aspects of care are
delivered.
Wickipedia September 2nd 2013
Lifestyle (smoking cessation, diet, physical activity) intervention, taking account of
psycho-social factors, and using a behavioural approach
Measuring, monitoring and managing other risk factors (blood pressure, lipids and
glucose) to target Understanding of, and adherence with,
cardioprotective drug therapies for life
SCORE: the European Risk Prediction SystemSCORE: the European Risk Prediction System
1994199820033rd Joint European Societies Task Force
2004European Society of Cardiology
Score enabled HeartScore, an interactive tool
• 12 European cohort studies• wide geographic spread of
countries at different levels of cardiovascular risks
• 3-million person-years of observation
• 7,934 fatal cardiovascular events
Data from:
SCORE
SCORE: the European Risk Prediction SystemSCORE: the European Risk Prediction System
1994199820033rd Joint European Societies Task Force
2004European Society of Cardiology
Score enabled HeartScore, an interactive tool
• 12 European cohort studies• wide geographic spread of
countries at different levels of cardiovascular risks
• 3-million person-years of observation
• 7,934 fatal cardiovascular events
Data from:
SCORE
Total risk assessment
SCORE: the European Risk Prediction SystemSCORE: the European Risk Prediction System
1994199820033rd Joint European Societies Task Force
2004European Society of Cardiology
Score enabled HeartScore, an interactive tool
• 12 European cohort studies• wide geographic spread of
countries at different levels of cardiovascular risks
• 3-million person-years of observation
• 7,934 fatal cardiovascular events
Data from:
SCORE
Total risk assessment
Total risk management
Lifestyle (smoking cessation, diet, physical activity) intervention, taking account of
psycho-social factors, and using a behavioural approach
Measuring, monitoring and managing other risk factors (blood pressure, lipids and
glucose) to target Understanding of, and adherence with,
cardioprotective drug therapies for life
Wood D A, et al Lancet 2008; 371: 1999-2012
EUROACTIONA European Society of Cardiology demonstration project:8 countries and 24 hospital and general practice centres
General hospitals and general practices
Dr Antonio Salvador, Cristina Buigues, Ana Bonet, Arancha Ruescas and Rosario Cuevas
Hospital General de Dr. Peset
Dr Jorge Navarro and Gemma Medez Perez
Centro de Salud de San Pau
Ambulatory nurse-coordinated multidisciplinary approach
The EUROACTION team in Boldrini Hospital, Thiene, Italy The EUROACTION nurse and
the lead GP in Hoensbroek, The Netherlands
Lifestyle change in families• No smoking• Saturated Fat: <10% total
Energy• Fruits and vegetables:
>400g/day• Fish: >20g/day• Oily Fish: >3 times/week• 30-45 minutes of physical
activity at 60–75% of the average maximum heart rate on four-five days of the week
• Weight reduction ≥ 5%• Waist <94 cm in men and
<80 cm in women
Smoking cessation
IncreasingPhysical activity
Healthy eating,Weight
management
Thiene, Italy
Halmstad, Sweden Valencia, Spain
Supervised hospital and home based physical activity
programme
One year assessment
Identification
Intervention
Randomisation
INT
PROGRAMME16 week hospital
1 year primary care
1965PATIENTS
UC
A CLUSTER RANDOMISED CONTROLLED TRIAL
Initial assessment
580SUB-SAMPLE
2179PATIENTS
2778PATIENTS
1632PARTNERS
910PARTNERS
626PARTNERS
2613PATIENTS
1999PATIENTS
1634PARTNERS
698PARTNERS
EUROACTION: HospitalSmoking cessation at one year in coronary patients who were smokers in the month
prior to their event
p = 0.06
+ 10% ( - 0.3% to + 21%)
EUROACTION: Hospitals Smoking status at baseline, 16 weeks and one year
(validated breath CO) in coronary patients
Proportions of patients achieving the European targets for a
healthy dietHospital General Practice
Intervention Usual Care
p = 0.005
p = 0.26
p = 0.13
p = 0.009
p = 0.004
p = 0.91
p = 0.04
Proportions of partners achieving the European targets for a
healthy dietHospital General Practice
p = 0.002
p = 0.42
p = 0.09
p = 0.31 p = 0.002
p = 0.98
p = 0.77
Intervention Usual Care
P = 0.002
General Practice+ 29% ( + 11% to + 48%)
Hospital+ 36% (+20% to + 51%)
P = 0.001
Proportion of patients achieving European Guidelines for physical
activity
Proportion of partners achieving European Guidelines for physical
activity
P = 0.06
General PracticeHospital
p = 0.03
+ 19% (- 0.6% to + 38%) + 27% (+ 4% to + 50%)
Proportion of patients achieving the European target for
blood pressure
P = 0.04
General PracticeHospital
p = 0.03
+ 17% (+ 2% to + 32%)+ 10% (+ 0.6% to + 20%)
Intervention Usual Care
Proportion of patients achieving European target for blood pressure
p = 0.04*
+ 17% (+ 0.5% to + 33%)
* random effects modelling
%
+ 19% (+ 1% to + 37%)
p = 0.04*
Patients without diabetes
Patients with diabetes
Proportion of patients on cardiovascular protective drug therapy
General PracticeHospital
Intervention Usual Care
p=0.28
p=0.16
p=0.26
p=0.53
p=0.04
p=0.06
p=0.91p=0.02
p=0.24
p=0.03
0.19
TerminologyCardiac rehabilitation
Cardiovascular rehabilitationRehabilitation and secondary
preventionCardiac rehabilitation and
preventionCardiovascular prevention and
rehabilitation
NICE Guideline: MI - secondary prevention
Cardiac rehabilitation programme is defined as:
ExerciseHealth education and information
Psychology and social support
NICE Guideline: MI - secondary prevention
Cardiac rehabilitation does NOT include:Lifestyle changes after MI:
Smoking cessationChanging dietary regimen
Alcohol consumptionWeight managementDrug therapy after MI
TerminologyCardiac rehabilitation
Cardiovascular rehabilitationRehabilitation and secondary
preventionCardiac rehabilitation and
preventionCardiovascular prevention and
rehabilitation
Cardiac rehabilitation and secondary prevention for patients with
established atherosclerotic disease+
Primary prevention for asymptomatic individuals at high risk of developing CVD including patients with diabetes
mellitus, CKD and other high risk diseases
MyAction is a modern preventive cardiology programmeintegrating secondary
and primary prevention in prevention centres
Victoria Medical Centre
St John & St Elizabeth, St. Johns Wood
Stowe Centre, Harrow Rd
MyAction Westminster: Centres
St Marys
Hospital
Victoria Medical Centre
St John & St Elizabeth, St. Johns Wood
Stowe Centre, Harrow Rd
MyAction Westminster: Prevention Centres
St Marys
Hospital
MyActionCommunity based
Integrates secondary and primary prevention
Nurse led and multidisciplinary:dieticians,
physiotherapists, psychologist, community cardiologist
Family centredProtocol based
Measures outcomes