The project is supported by the European Commission in the framework of the Public Health Programme.

DELIVERABLE D1 - PROJECT PRESENTATION

PROJECT’S INFORMATION

Start date 1st of November 2008

End date 30th of April 2011

Project duration 30 months

Coordinator GiViTI

Number of partner 8

Total cost € 1.343.633

Budget (60%) € 806.177

GENERAL OBJECTIVE

The aim is to promote patient safety and quality improvement in critical care towards a

significant reduction of observed mortality rates and economic costs

THE LEADING IDEAS

Self-evaluation is the most powerful means by whichan institution can experience a discontinuity ofperception that can drive improvement.

Comparing own performance against others is the bestway to promote self-evaluation.

PROSAFE provides ICUs with a method to continuously,easily, rigorously, and confidently measure ownperformance against others. By joining the project, an ICUwill be helped to find out more about its adjustedmortality rate and to analyze the contributing factors.

S Strengths W Weaknesses

O Opportunities T Threats

PROSAFE will help ICUs to identify theirown Strengths and Weaknesses, and tofind out the Opportunities and Threatsinvolved in improving performance incritical care.

WHAT CAN AN ICU RECEIVE?This ICU has an overall mortality rate in line with what is expectedfrom its case-mix. Nonetheless, analysis of the Calibration curve (aPROSAFE output) shows that the unit has strengths in less severepatients (with expected mortality lower than 30%) and weaknessesin sicker ones (with expected mortality between 40% and 70%). ThisICU will have to concentrate on improving performance in the lattergroup.

This ICU experienced 13 more deaths than expected.The VLAD curve (an output of the project) shows twoperiods of crisis in performance: from February to theend of May and from September to the end ofNovember. The unit must find out what happened inthese periods to improve performance.

CONSORTIUM

GiViTI (Italian Group for the Evaluation of Interventions in Intensive Care Medicine)“Mario Negri” Institute,Italy

Semmelweis University,Hungary

Warsaw Medical University,Poland

General hospital Novo Mesto,Slovenia

Nicosia General Hospital,Cyprus

Intensive Care Forum NGO,Cyprus

Friedrich-Schiller-Universitat Jena,Germany

UCL Center for Intensive Care Medicine & Bloomsbury Institute of Intensive Care Medicine,United Kigdom

ABOUT THE PROJECT

The project will be carried out by an Intensive care network composed of a Coordination

centre based in Italy (GIVITI group), a consolidated network which involves about 350

Italian ICUs, 3 pilot sites which involve 5-10 Intensive care units each (Poland, Hungary

and Slovenia), 1 future network which involves 1 ICU in Cyprus. Moreover a future

network will be established in Brazil as an external collaboration. Project activities will be

monitored by an advisory board composed of experts in the domain from Germany and

UK. The EU network will benefit from Italy's long consolidated experience (Margherita

project) in the field of critical care.

THE NETWORK

WP8

Coordination

of the project

WP9

Dissemination of the results

WP10

Evaluation

of the

project

WP2

System implementation

and localization

WP3

Critical care data

collection

WP4

Statistical analysis and

reporting

WP5

ICUs networks

management & good

practices exchange across

Europe

WP1

Case Report Form

Start: 1 End: 30

WP Leader: Slovenia

Start: 9 End: 30

WP Leader: Poland

Start: 1 End: 9

WP Leader: Hungary

Start: 1 End: 30

WP Leader: Germany

Start: 1 End: 30

WP Leader:

GiViTI

Start: 2 End: 30

WP Leader: UK

WORKPACKAGES STRUCTURE

Start: 6 End: 30

WP Leader: GiViTI

Start: 1 End: 18

WP Leader: GiViTI

WP1 – Case report form (Leader: Hungary)Discuss and agree the core dataset to be collected (M4)State of the art and input to standard nomenclature and codifications

WP2 – System implementation and localization (Leader: GiViTI)

Develop the data collection system (beta version M9 – final version M12)Localize in national language the system (M9)

WP3 – Critical care data collection (Leader: Poland)

Data collection (M9-M30)

6 months – Draft report

12 months – Final reportM12 M24

Data Collection scheme

M12 M18

WP4 – Statistical analysis and data reporting (Leader: GiViTI)

Specification of statistical analysis and core indicators (M9)

Data analysis and performances comparison (M10-M30)

Statistic Reports (Draft M18-20, Final M24-28)

WP5 - ICU networks management and good clinical practices exchange across EU (Leader: Slovenia)

Manage 1 consolidated network (Italy), establish and manage 3 pilot networks (Hungary, Poland, Slovenia), establish and manage 2 future networks (Cyprus, Brazil)

Fellowships in centres of excellence(M18-30)

WP8 – Coordination of the project (Leader: GiViTI)Project management

Technical management, data management

Technical and financial reports

WP9 – Dissemination of results (Leader: Germany)

Disseminate project results

Organize international workshop and national meetings

WP10 – Evaluation of the project (Leader: UK)

Continuous project evaluation

PUBLIC PROJECT DELIVERABLES

Deliverable

No

Deliverable title Delivery date Confidentiality

level

D 1 Project presentation : This deliverable includes a project presentation and a project leaflet that summarize

the project activities and aim to enhance future collaborations

M6 Public

D 3 Case report form: This deliverable includes the description of data to be collected through the system and

lists the quality indicators identified for statistical analysis

M4 Public

D 5.1 General report of critical care quality improvement and patient safety at EU level: This deliverable

presents a description of all data collected at EU level and provides statistical analysis results as an

instrument to improve quality of care and patient safety in critical care

M28 Public

D 5.2 National reports of critical care at country level: This deliverable presents data and statistical analysis of

each country in the network and allows performance to be compared at national level

M28 Public

D 6 International guidelines: this deliverable contains the results of knowledge consolidation in ICU

management and will propose protocols and guidelines with regard to specific procedures in critical care

domain

M 28 Public

D 8 Dissemination report: this deliverable describes the dissemination strategy, the activities performed to

divulgate project results, the stakeholders contacted and other information related to dissemination

activities.

M 30 Public

Name Date Description

Kick-off meeting Month 1November 2008

Project start (presentation of roles, activities, partners) + initial discussion concerning case report form (international core and national cores)

Technical meeting Month 4February 2009

CASE REPORT FORM, system specifications

Mid-term technical meeting and review

Month 10 August 2009

Presentation of beta version of web-based data collection system + discussion concerning statistics and reports

International workshop + final meeting

Month 28 February 2011 Presentation of project results to project participants and to external target groups + project finalization

National meetings Month 12- Month 14 October 2009-December2009

Presentation of PROSAFE system to participating ICUs in each pilot country and collection data start (Hungary, Poland, Slovenia)

National meeting Month 28 February 2011

Presentation of PROSAFE results and planning for taking up of the future network established in Cyprus

National meeting Month 28 February 2011

Presentation of PROSAFE results and planning for taking up of the future network established in Brazil

EXPECTED RESULTS

The main expected outcomes of the project are:

Web-based multilingual data collection system

Comparison of statistics and performance

across the participating ICUs

Good practice exchange

CONTACTSGiViTI (Italian Group for the Evaluation of Interventions in Intensive Care Medicine)Mario Negri Institute for Pharmacological ResearchVilla Camozzi, via Camozzi 3, 24020 Ranica Bergamo, Italy

Guido Bertolini, Project leader - Physician and Epidemiologist

Phone: +39 035 45 35 313

Fax: +39 035 45 35 371

E-mail: giviti@marionegri.it

Skype contact: giviti

Site: http://prosafe.marionegri.it