Effects of Pesticides Identified in the Hematopoietic System

Pesticide Health Effects Medical Education Database (PHEMED)

Effects

• Hemolysis • Methemoglobinemia • Hypoprothrombinemia • Hyperkalemia • Hypocalcemia • Hypercalcemia • Carboxyhemoglobinemia • Anemia

• Leukopenia, thrombocytopenia

• Elevated LDH, GOT, GPT, alkaline phosphatase, ALT, AST enzymes

• Depressed RBC acetylcholinesterase & plasma pseudocholinesterase

Hematopoietic

• Hemolysis • Naphthalene • Sodium chlorate • Arsine

• Hypoprothrombinemia • Coumarins • Indandiones

• Methemoglobinemia • Sodium chlorate • Creosote

• Carboxyhemoglobinemia • Organotin compounds

EffectEffect Characteristic of poisoning w/Characteristic of poisoning w/

• Leukopenia • Thrombocytopenia

• Inorganic arsenicals

• Anemia • Naphthalene • Sodium chlorate • Arsine • Inorganic arsenicals

HematopoieticEffectEffect Characteristic of poisoning w/Characteristic of poisoning w/

Blood ChemistriesBlood Chemistries

• Hyperkalemia • Sodium chlorate• Naphthalene • Arsine

• Hypocalcemia • Fluoride

• Hypercalcemia • Cholecalciferol

EffectEffect Characteristic of poisoning w/Characteristic of poisoning w/

Elevated LDH, GOT, GPT, alkaline phosphatase, ALT, AST enzymes

• Carbon tetrachloride• Chloroform• Phosphine

• Depressed RBC acetylcholinesterase and plasma pseudo-cholinesterase

• Organosphosphates

EnzymesEnzymesEffectEffect Characteristic of poisoning w/Characteristic of poisoning w/