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DR.FAİK ORUCOV
İSTANBUL SURGERY HOSPİTALDEPARTMANT OF CATARACT AND REFRACTİVE
SURGERY
Accomodative and Multifocal IOL implantations
i s t a n b u l c e r r a h i h a s t a n e s i
Crystalens AT-45
Accomodative,monofocal IOL,pupil independent
4.5 mm silicon optic (now also available as 5 mm)
Plate haptic 1.5 mm thickness Lens responds to the
natural accommodative response(with the ciliary
muscle contraction vitreus pressure increases pushes the IOL optic forward)
11.5 mm diameter
i s t a n b u l c e r r a h i h a s t a n e s i
56 eyes of 30 patientsCataract surgery
between december 2002- september 2005 with facoemulsification
AT-45 Crystalens implantation
14 male 16 female 4 years follow up
Crystalens i s t a n b u l c e r r a h i h a s t a n e s i
Review: multifocal IOLs
Retrospective analysis of 124 patients(223 eyes)
Surgeries from October 05 –May 07 Postop expected bcva 20/40 or over (can be
measured by potential acuity meter) with No anterior segment or retinal pathology
Small incision facoemulsification Monoculer,binoculer implantationMix-match
i s t a n b u l c e r r a h i h a s t a n e s i
Demographics:
Female: 62 % Male: 38 %Age: 7-82 (Mean=60.7)Preop refraction Seq -14.25 to +9.25 78 myopic 26 emetropic 119 hypermetropic eyes6 months to 2 years follow up timeAverage one year28 % ≤ 6 months72 % ≥ 6months
i s t a n b u l c e r r a h i h a s t a n e s i
Diffractive
1st generation zonal refractive
far focusnear focus
Refractive monofocal
far focus
Optical Principles of IOLs
near focus far focus
AMO Rezoom-Refractive multifocal IOL
Large distant dominant central zone in bright light conditions and
four periferal zones that provide near,intermediate and distance focus
Pupil dependent +3.5 D near add acrylic hydrophobic OptiEdge (less capsule opasification) Biconvex ModC, Angle 5° Haptics PMMA Optic 6.0, length 13.0mm Power +6.0 +30.0 D (steps 0.5D) A-constant 118.4
i s t a n b u l c e r r a h i h a s t a n e s i
Rezoom i s t a n b u l c e r r a h i h a s t a n e s i
near focus far focus
1st generation zonal refractive principle
Tecnis IOL
Diffractive posterior surface with 32 concentric rings
Light distribution of 50 % for distance vision, 50% for near vision
add +4:0 DTecnis:distribution of focus is independent of pupil size5-34 DSiliconA-constant 119
i s t a n b u l c e r r a h i h a s t a n e s i
Diffractive TECNIS ZM001
+ ACE Cornea
near focus far focus
Acri.lisa IOL
Distance –dominant -diffractive multifocal IOLIndependent of pupil sizeSmooth steps in the refractive diffractive
structureLight distribution is not equal for far and near
vision (Asymmetrical light distribution) 65/35% AcrylicA-constant 11810-30 dpt
i s t a n b u l c e r r a h i h a s t a n e s i
ReSTOR multifocal IOL
• Appodized(gradually decreasing steps) diffractive optic at the center of the anterior surface ,refractive optical zones towards periphery
• 10-3o dpt• A-constant 118.2• +4.0 Add • Reduced photic phenomena like glare,halos,low
contrast sensitivity
i s t a n b u l c e r r a h i h a s t a n e s i
Pre-op examinations
Preop full examinations:BcvaDominant –nondominant eye selectionOculer TensionRetina and anterior segment examinationTopographyOculyzer –PentacamContrast sensitivityPotential acuity meterPupillometryBiometryPachymeter Tear film quality (punctum plugs if required)
i s t a n b u l c e r r a h i h a s t a n e s i
IOL selection
Expectations should be well discussed in detail
before the operation Driving,computer usage,reading,working
distanceDistance vision may be affected by glare at low
light conditionsNeuro-adaptation (takes time)Possibility of another procedure(lasik) for better
visionMay need reading glasses in dim light
i s t a n b u l c e r r a h i h a s t a n e s i
Biometry
Repeated measurementsCheck keratometer measurementsSrk-t for emetropics,myopicsHaigis for high hyperopiasCheck first eye’s refraction at least one week
after the operation and then plan the second eyeFor crystalens binoculer implantations postop -
0.5 D myopia planning for the first eye , emmetropia for the second eye
i s t a n b u l c e r r a h i h a s t a n e s i
Surgery
FacoemulsificationTopical anesteshiaCorneal tunnel incision in the steepest axis
(don’t consider astigmatism due to crystalline lens)
Capsulorexis smaller than optic diameter Posterior capsule polishingCare to the optic of the IOLIntracapsuler ring may be implanted if
necessary!
i s t a n b u l c e r r a h i h a s t a n e s i
Post-op testing
Ucva at distant, intermediate and nearBcva at distant, distant corrected
intermediate and nearContrast sensitivity and glare was checked by
Ophtec 6500 sine wave gratings of 5 different spatial frequencies: 1.5, 3, 6, 12, cycle per degree
Patient satisfaction questionarie
i s t a n b u l c e r r a h i h a s t a n e s i
Crystalens – Four Year Results
First week after the surgery with the back and front movement of the IOL -0.5 and -2.0D transient myopia was found but disappeared in one week
Post op mean refractive error Seq was :±0.75Bcva for distant is between 20/32-20/20Distance corrected near vision (40 cm) is between J 7
–J9Distance corrected intermediate vision (80 cm) is
between J5 - J7 Mean addition required for reading was
1.5 ± 0.35 D 6 months after the operation 2.25±0.25 D 4 years after operation, increased in time
i s t a n b u l c e r r a h i h a s t a n e s i
Crystalens results
According to the two years follow up, accomodative IOLs are satisfactory for the daily activities but 85 % patients need glasses for near reading
Near vision reading capacity decreased in time Overall patient satisfaction mean score was 2 over
4 Patient satisfaction depends on occupation and
daily activitiesHigh patient satisfaction for distance
i s t a n b u l c e r r a h i h a s t a n e s i
Multifocal IOL - Results
Capsuler ring was placed in two eyes because of zonnuler defect
3 implantations to sulcus (posterior capsula perforation)Three eyes had inflammation 2 weeks after Tecnis IOL
implantationTwo of them undergone seconder IOL exchange
operationYag capsulotomy was needed in 7 patientsPostop secondary excimer lazer treatment was
performed in 12 patients (5 %)Mean monoculer post operative refractive error Seq
after secondary treatment was ±0.50
i s t a n b u l c e r r a h i h a s t a n e s i
Contrast Sensitivity-Results
Contrast sensitivity functions of all multifocal and accomodating IOLs were within the reference rate of normal limits, but lower than monofocal group
At the middle and high spatial frequencies contrast sensitivity in the diffractive group was lower than refractive group
i s t a n b u l c e r r a h i h a s t a n e s i
3 Main groups
Mix-match:Rezoom-Tecnis 26 patientsRezoom-Acri.Lisa 21 patients Bilateral -multifocal same IOL:Rezoom-Rezoom 21 patientsAcri.Lisa-Acri.Lisa 12 patients Monoculer- multifocal implantation(other eye not
operated):Rezoom one eye 22 patientsAcri.Lisa one eye 13 patientsTecnis 9 patients
i s t a n b u l c e r r a h i h a s t a n e s i
MIX-MATCH
PATIENT NO
FREE OF GLASSE
S
HALOGLARE
NEAR
INTERMEDIATE FAR
RezoomTecnis
26 98% 75% J1.6 J2 20/20
Rezoom Acri.Lisa
21 75% 60% J 1.6 J2 20/25
i s t a n b u l c e r r a h i h a s t a n e s i
BINOCULER SAME IOL
PATIENT NO
FREE OF GLASSES
HALOGLARE
NEAR INTERMEDIATE FAR
Acri.LisaAcri.Lisa
12 85% 70% J 1.5 J 2 20/20
Rezoom Rezoom
21 75% 60% J 2 J 2 20/25
i s t a n b u l c e r r a h i h a s t a n e s i
MONOCULER DISTANCE CORRECTED VISUAL ACUITIES
NEAR INTERMEDIATE DISTANT
Tecnis J1.6 J2.1 20/20
Rezoom J2.2 J1.8 20/25
Acri.Lisa J1.5 J2 20/20
Restor J2 J2.2 20/20
i s t a n b u l c e r r a h i h a s t a n e s i
Questionnaries
Halo,glare(subjective experience)Near,intermediate, distant visionDriving (day,night)Reading (newspaper,maps,prescriptions)Activities(sports, shopping)Patient satisfaction1-bad2-fair3-good4-very good
i s t a n b u l c e r r a h i h a s t a n e s i
PATIENT SATISFACTION
HALO GLARE
NEAR INTERMADIATE DISTANT
Rezoom 2 3 4 3
Tecnis 3 4 2 4
Acri.Lisa 3 4 3 4
Restor 3 3 2 3
i s t a n b u l c e r r a h i h a s t a n e s i
Overall glare
11%
2%
10%
5%
17%
55%
night driving
night
at bright light
always
none
room light
i s t a n b u l c e r r a h i h a s t a n e s i
Night driving
Night
At bright light
Always
None
Room light
Glare
Rezoom 76 %Tecnis 62 %Acrilisa 58 %ReStor 56 %Crystalens 50%
i s t a n b u l c e r r a h i h a s t a n e s i
Multifocal IOL Patient Satisfaction
Overall satisfaction rate is 3.592% of the patients would have the same
implant again70% of the patients have some complaints while
night driving79 % glasses free(computer, newspaper,outdoor
activities)18 % wear glasses for reading smallprints3 % wear glasses for distant (driving)
i s t a n b u l c e r r a h i h a s t a n e s i
Conclusions
Diffractive IOLs are pupil independent and for myopic patients who read alot
Reezoom more pupil-size dependet Too small (pupils) poor reading ability , Too large - more halos
Refractive IOL’s (Rezoom) optical performance is better for intermediate vision
With monofocal-multifocal combination :satisfactory binoculer near vision (%70)
Best near vision with acri.Lisa is from 30-35 cm with ReZoom 45 cm
i s t a n b u l c e r r a h i h a s t a n e s i