Disinformation from Press Releases? Peter Steele Current Patents Ltd London W1T 4LB [email protected] Current Patents Ltd

Disinformation from Press Releases?

Peter Steele

Current Patents LtdLondon W1T 4LB

[email protected]

www.current-patents .com

Current Patents Ltd - ACS, San Diego, April 2001

Background


10,000 pharma/biotech press releases analysedeach year for Investigational Drugs database (IDdb)

10% with IP implications - four per day

Analysis for technical intelligence by skilled analysts

Grey Literature


Formal

JournalsPatentsTechnical ReportsMeetings

Grey

AdvertisementsNewspapersBrochuresBroadcastsAnalysts’ BriefingsAnnual ReportsPress releases

Grey Literature


Formal

Journals(Patents) Technical ReportsMeetings

GreyPatentsAdvertisementsNewspapersBrochuresBroadcastsAnalysts’ BriefingsAnnual ReportsPress releases

Intelligence = Effort


Press Releases DOLPHIN(Database of All Pharmaceutical Inventions)

One analyst – 3 to 4 days/week

Sources - general (1)


•PR Newswire•Business Newswire•Canada Newswire

Medical, Hospital and Biotech sections

•Direct email from companies



•CAS Chemical industry newswww.cas.org/reuters/chemnews.html

•Daily industry news, individually profiledwww.office.com



•Pharmaceutical News & Informationwww.coreynahman.com

•Pharmalicensingwww.pharmalicensing.com

•Hoover’s Onlinewww.hoovershbn.hoovers.com

•Bioresearch Onlinewww.news.bioresearchonline.com

Sources - Patent


•USPTO Official Gazettewww.uspto.gov/web/offices/com/sol/og

•UK Official Journalwww.patent.gov.uk/patent/notices

•Australian PO Decisionswww.austlii.edu.au/au/cases/cth/APO

•UK Court Judgementswww.wood.ccta.gov.uk/courtser/judgements.nsf

Country of Origin


US 235UK 17Canada 16Germany 8Switzerland 7Others (NL,FR,IL,JP

DK,SE,AT) 17

State of Origin


CA 97NJ 30MA 28WA 14PA 10NY 9MD 8Others (16) 40

Multinationals’ PRs


Issuing Party – 30/300 (10%)

Second Party – 68/300 (23%)

Non-Government – 68/200 (34%)

Three or more PRs issued


Abgenix,AntexAriadArquleCoulterGenzyme

IncyteMaxygenMyriadSciCloneViragenVivusXTL

Partnerships in Press Releases


First (issuing) party with Second Party etc

67% Company with Company/Institution

33% Company with Government Agency22% USPTO11% FDA

Technology Types


65% Fundamental (“platform”)

35% Product Oriented (69)Preclinical (21)Phase I (16)Phase II (12)Phase III (6)Marketed (14)

Details to Cite


Patent Number - get it right!!!

Inventor Names

Date and country of origin

Identity of Originator – other interests?

Name of Product/Technology

Case Study (1): Immutech


“…….announced today it had been issued US Patent No 6172104B1entitled “Dicationic dibenzofuran……..” March 26,2001

Actually issued January 9, 2001Assignee is University of North CarolinaUS Government (NIH) retains interestOriginates from joint program with Georgia, Duke &Auburn universities

Case Study (2): “Interleukin Genetics…


….announced today that it was awarded Patent No 6210877 for the discovery that certain IL-1 gene variations…receiveda Notice of Allowance in June 2000” March 29, 2001

US6210877 was not published until April 3, 2001Published previously as PCT (WO9840517, Sept 1998)June 2000 announcement referring to PCT wouldhave been more helpful!

Case Study (3): Roche…..


…receives EU approval for Herceptin…..discovered anddeveloped by Genentech…… Aug 30, 2000

Protein Design Labs and the US Army hold fundamentalpatents covering many humanized antibodiesGenentech is a non-exclusive licensee of PDL

Case Study (4): Abbott…


…and Triangle Pharma….results of phase I/II trial in which DAPD…UNC investigators conducting study….

DAPD claimed by Emory University in 1992Emory has interference & opposition actions with BioChem Pharma

Press Releases: Conclusions


Take nothing for grantedExpect contradictionsExpect old informationExpect wrong numbers/dates………

“At best, a good press release can be an excellent source of

technical intelligence – but that applies to only 10-20% of

examples……”


“….at worst there can be a lot of skilled effort required to extract and codify that intelligence, and

sometimes there is nothing of substance to be said.”


Disinformation from Press Releases?

Yes, if you’re not careful!

Peter Steele

Current Patents Ltd, [email protected] .com


Documents

Disinformation from Press Releases? Peter Steele Current Patents Ltd London W1T 4LB [email protected] Current Patents Ltd