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DETERMINATION OF UNSTEADY CONTAINER TEMPERATURES DURING FREEZING OF THREE-DIMENSIONAL ORGANS WITH CONSTRAINED THERMAL STRESSES Brian Dennis Aerospace Engineering Penn State University G.S. DULIKRAVICH Multidisciplinary Analysis, Inverse Design, and Optimization (MAIDO) Department of Mechanical and Aerospace Engineering The University of Texas at Arlington

DETERMINATION OF UNSTEADY CONTAINER TEMPERATURES DURING FREEZING OF THREE-DIMENSIONAL ORGANS WITH CONSTRAINED THERMAL STRESSES Brian Dennis Aerospace Engineering

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Page 1: DETERMINATION OF UNSTEADY CONTAINER TEMPERATURES DURING FREEZING OF THREE-DIMENSIONAL ORGANS WITH CONSTRAINED THERMAL STRESSES Brian Dennis Aerospace Engineering

DETERMINATION OF UNSTEADY CONTAINER TEMPERATURES DURING FREEZING OF THREE-DIMENSIONAL

ORGANS WITH CONSTRAINED THERMAL STRESSES

Brian DennisAerospace EngineeringPenn State University

G.S. DULIKRAVICHMultidisciplinary Analysis, Inverse Design, and Optimization (MAIDO)

Department of Mechanical and Aerospace EngineeringThe University of Texas at Arlington

Page 2: DETERMINATION OF UNSTEADY CONTAINER TEMPERATURES DURING FREEZING OF THREE-DIMENSIONAL ORGANS WITH CONSTRAINED THERMAL STRESSES Brian Dennis Aerospace Engineering

Objectives

• Use finite element method(FEM) model of transient heat conduction and thermal stress analysis together with a Genetic Algorithm(GA) to determine the time varying temperature distribution that will cool the organ at the maximum cooling rate allowed without exceeding allowed stresses

Page 3: DETERMINATION OF UNSTEADY CONTAINER TEMPERATURES DURING FREEZING OF THREE-DIMENSIONAL ORGANS WITH CONSTRAINED THERMAL STRESSES Brian Dennis Aerospace Engineering

Mathematical Model

0Xu2Gzx

w2

yx

v2

2x

u2 G

Thermoelasticity

0Yv2Gzy

w2

2y

v2

yx

u2 G

0Zw2G2z

w2

zy

v2

zx

u2 G

12

EG ,

211

E

x

TG23X

y

TG23Y

z

TG23Z

Page 4: DETERMINATION OF UNSTEADY CONTAINER TEMPERATURES DURING FREEZING OF THREE-DIMENSIONAL ORGANS WITH CONSTRAINED THERMAL STRESSES Brian Dennis Aerospace Engineering

Mathematical ModelHeat Conduction

Tk t

TCeffective

dT

dHCeffective

2

1

222

222

dzdT

dydT

dxdT

dzdH

dydH

dxdH

dT

dH

Page 5: DETERMINATION OF UNSTEADY CONTAINER TEMPERATURES DURING FREEZING OF THREE-DIMENSIONAL ORGANS WITH CONSTRAINED THERMAL STRESSES Brian Dennis Aerospace Engineering

Comparison with Analytic Solution

0 1 2 3 4Time

25

30

35

40

45T

AnalyticNumerical

Page 6: DETERMINATION OF UNSTEADY CONTAINER TEMPERATURES DURING FREEZING OF THREE-DIMENSIONAL ORGANS WITH CONSTRAINED THERMAL STRESSES Brian Dennis Aerospace Engineering

Geometry and Material Properties

• Actual Geometry from MRI or other sources was not available so a kidney like object was constructed from analytical functions

• Some material properties are available in various publications but some had to be estimated for this test case

• The procedure can be easily repeated when accurate geometry and material data are available

Page 7: DETERMINATION OF UNSTEADY CONTAINER TEMPERATURES DURING FREEZING OF THREE-DIMENSIONAL ORGANS WITH CONSTRAINED THERMAL STRESSES Brian Dennis Aerospace Engineering

Algorithm

Ti = Tinitial

t = 0

run GA with analysisusing t=tI to tf and T=Ti

tf=tI+t

Ti=Tbest

is kidneyTmax < Tfrozen

N

Y

END

START

Page 8: DETERMINATION OF UNSTEADY CONTAINER TEMPERATURES DURING FREEZING OF THREE-DIMENSIONAL ORGANS WITH CONSTRAINED THERMAL STRESSES Brian Dennis Aerospace Engineering

Outer Boundary

-1

-0.5

0

0.5

1

Z

-1

-0.5

0

0.5

1

X

-1

-0.5

0

0.5

1

Y

X Y

Z

Page 9: DETERMINATION OF UNSTEADY CONTAINER TEMPERATURES DURING FREEZING OF THREE-DIMENSIONAL ORGANS WITH CONSTRAINED THERMAL STRESSES Brian Dennis Aerospace Engineering

Kidney Cortex

X

Y

Z

Page 10: DETERMINATION OF UNSTEADY CONTAINER TEMPERATURES DURING FREEZING OF THREE-DIMENSIONAL ORGANS WITH CONSTRAINED THERMAL STRESSES Brian Dennis Aerospace Engineering

Kidney Medula

X Y

Z

Page 11: DETERMINATION OF UNSTEADY CONTAINER TEMPERATURES DURING FREEZING OF THREE-DIMENSIONAL ORGANS WITH CONSTRAINED THERMAL STRESSES Brian Dennis Aerospace Engineering

Kidney Cortex and Medula

X

Y

Z

Page 12: DETERMINATION OF UNSTEADY CONTAINER TEMPERATURES DURING FREEZING OF THREE-DIMENSIONAL ORGANS WITH CONSTRAINED THERMAL STRESSES Brian Dennis Aerospace Engineering

Parameterization

• Outer sphere (cooling container) divided into six equally spaced patches.

• Each patch is covered by biquadratic Lagrange polynomials with nine nodes

• 26 design variables describing container surface temperature

• Allowed to vary from +20 C to -30 C

Page 13: DETERMINATION OF UNSTEADY CONTAINER TEMPERATURES DURING FREEZING OF THREE-DIMENSIONAL ORGANS WITH CONSTRAINED THERMAL STRESSES Brian Dennis Aerospace Engineering

Objective Function

2

yield

maxPt

TF

If( max stress > yield stress)

P = 100

else

P = 0

Minimize average cooling rate with max. stress as a constraint

Page 14: DETERMINATION OF UNSTEADY CONTAINER TEMPERATURES DURING FREEZING OF THREE-DIMENSIONAL ORGANS WITH CONSTRAINED THERMAL STRESSES Brian Dennis Aerospace Engineering

Numerical Results• Time interval for outer loop was 5

minutes

• Time step for analysis was 15 seconds

• Was run for 30 minutes (6 surface temperature distribution optimizations)

• Grid with 5184 parabolic tetrahedral elements was used for heat conduction

• Grid with 5184 linear elements was used for stress analysis

Page 15: DETERMINATION OF UNSTEADY CONTAINER TEMPERATURES DURING FREEZING OF THREE-DIMENSIONAL ORGANS WITH CONSTRAINED THERMAL STRESSES Brian Dennis Aerospace Engineering

GA Parameters Used• Each design variable represented with 4-bit

binary string• Uniform crossover operator was used• 50% probability of crossover, 2% probability

of mutation• 15 generations were run for each optimization• Used a population size of 31• Was run on a 32 processor parallel computer

composed of commodity components• One optimization takes ~45 minutes

Page 16: DETERMINATION OF UNSTEADY CONTAINER TEMPERATURES DURING FREEZING OF THREE-DIMENSIONAL ORGANS WITH CONSTRAINED THERMAL STRESSES Brian Dennis Aerospace Engineering

Numerical Results

10 20 30time(min)

2

4

6

8

10

12

14

16

18

maxstress

(MPa)

Page 17: DETERMINATION OF UNSTEADY CONTAINER TEMPERATURES DURING FREEZING OF THREE-DIMENSIONAL ORGANS WITH CONSTRAINED THERMAL STRESSES Brian Dennis Aerospace Engineering

Numerical Results

10 20 30time(min)

-2.25

-2

-1.75

-1.5

-1.25

-1

-0.75

-0.5

averagedT/dt(degreesC/sec)

Page 18: DETERMINATION OF UNSTEADY CONTAINER TEMPERATURES DURING FREEZING OF THREE-DIMENSIONAL ORGANS WITH CONSTRAINED THERMAL STRESSES Brian Dennis Aerospace Engineering

Numerical Results

5 10 15generation

-0.007

-0.006

-0.005

-0.004

-0.003

-0.002

-0.001

0

0.001

0.002

0.003

0.004

0.005

averagedT/dt

Page 19: DETERMINATION OF UNSTEADY CONTAINER TEMPERATURES DURING FREEZING OF THREE-DIMENSIONAL ORGANS WITH CONSTRAINED THERMAL STRESSES Brian Dennis Aerospace Engineering

Numerical Results

-1 -0 .8 -0 .6 -0 .4 -0 .2 0 0 .2 0 .4 0 .6 0 .8 1Y

-2 0

-10

0

10

T

T a t 1 0 m inT a t 1 5 m inT a t 2 0 m inT a t 2 5 m inT a t 3 0 m in

Page 20: DETERMINATION OF UNSTEADY CONTAINER TEMPERATURES DURING FREEZING OF THREE-DIMENSIONAL ORGANS WITH CONSTRAINED THERMAL STRESSES Brian Dennis Aerospace Engineering

Conclusion• An algorithm was developed for the inverse

determination of surface temperature distributions in the freezing of a kidney organ

• Current results show that after 30 minutes the kidney is not entirely frozen and more time intervals are needed

• This simulation process was made practical through the use of parallel optimization algorithms(GA) and cheap parallel computer composed of PC components

Page 21: DETERMINATION OF UNSTEADY CONTAINER TEMPERATURES DURING FREEZING OF THREE-DIMENSIONAL ORGANS WITH CONSTRAINED THERMAL STRESSES Brian Dennis Aerospace Engineering

Results(movie)

Animation of temperature contours along slice at z=0 for every 5 minute interval

Page 22: DETERMINATION OF UNSTEADY CONTAINER TEMPERATURES DURING FREEZING OF THREE-DIMENSIONAL ORGANS WITH CONSTRAINED THERMAL STRESSES Brian Dennis Aerospace Engineering

Results( movie)

Animation of container surface temperature contours for every 5 minute interval